Abstract: The invention discloses an implant. The implant may include a first flap and a second flap. The first flap may further include a first portion, a second portion and a transition region. The first portion may be configured to be attached proximate a sacrum. The second portion may be configured to be attached to an anterior vaginal wall. The transition region lies between the first portion and the second portion. The second flap may be fabricated such that a portion of the second flap is configured to be attached to a posterior vaginal wall. The implant may be configured such that a value corresponding to a biomechanical parameter defining a biomechanical attribute of the portion of the first flap attaching to the anterior wall is different from a value of the biomechanical parameter defining the biomechanical attribute of the portion of the second flap attaching to the posterior wall.

Abstract: A retrieval device attachable to a scope includes a handle which has an attachment portion configured to couple the handle to the scope; a shaft coupled to the handle having a wire immovably coupled to the handle; and a sheath movable relative to the handle over the wire between a distal position and a proximal position via an actuator of the handle. The actuator actuates a slider assembly of the handle. The slider assembly is coupled to the sheath and movable relative to the attachment portion to move the sheath and an expandable end effector coupled to the distal end of the wire. The end effector is movable between a collapsed configuration when the sheath is moved distally to the distal position to cover the end effector and an expanded configuration when the sheath is moved proximally to the proximal position, uncovering the end effector.

Abstract: A ureteroscope system includes a handle; an elongated shaft extends from the handle to a distal end and includes a working channel which is opened at the distal end; an external member extends from a proximal end to a distal end and is coupled to the shaft, the member includes a hub and a tube defining a first external channel; and a coupling mechanism defines first and second tubes and is coupled the distal end of the member to the distal end of the shaft. The first tube defines a first lumen and the second tube defines a second lumen which is sized and shaped to receive a distal end of the member. A proximal portion of the first tube is sized and shaped to be inserted into a distal portion of the shaft such that the first lumen is opened to the working channel.

Abstract: A fluid management system may include a fluid pump capable of generating a pulsatile flow of fluid, a fluid pathway for transporting the pulsatile flow of fluid from a fluid source through the fluid pump to a medical device, a dampening element in fluid communication with the fluid pathway and operably independent of the fluid pump, the dampening element comprising one or more barrels, each barrel including a movable seal member disposed within the barrel and a biasing member disposed within the barrel and engaged with the movable seal member, the dampening element being responsive to pressure fluctuations of the pulsatile fluid flow to actively dampen the pressure fluctuations, and a fluid flow sensor disposed along the fluid pathway between the dampening element and the medical device to measure a flow rate of the smoothened pulsatile fluid flow in both flow directions.

Abstract: The invention discloses an implant. The implant may include a first flap and a second flap. The first flap may further include a first portion, a second portion and a transition region. The first portion may be configured to be attached proximate a sacrum. The second portion may be configured to be attached to an anterior vaginal wall. The transition region lies between the first portion and the second portion. The second flap may be fabricated such that a portion of the second flap is configured to be attached to a posterior vaginal wall. The implant may be configured such that a value corresponding to a biomechanical parameter defining a biomechanical attribute of the portion of the first flap attaching to the anterior wall is different from a value of the biomechanical parameter defining the biomechanical attribute of the portion of the second flap attaching to the posterior wall.

Abstract: Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.

Abstract: A handle assembly includes a drive wire coupled to an expandable end effector, the wire having a diameter of no more than 3 French and a handle cannula receiving the wire therethrough, rotation of the handle cannula transferring torque to rotate the wire. The assembly also includes a shaft receiving the handle cannula, rotation of the shaft transferring torque to rotate the handle cannula. The assembly further includes an actuation assembly receiving the shaft, the actuation assembly coupled to a sheath sized to receive the wire and end effector therethrough, the actuation assembly moveable between a proximal configuration in which the sheath is moved proximally to expand the end effector and a distal configuration in which the sheath is moved distally to retract the end effector, the actuation assembly including a rotation mechanism transferring torque to the shaft to rotate the shaft.

Abstract: A medical device may include an introducer sheath, having a distal and a proximal end and a lumen extending from the distal end to the proximal end. The introducer sheath may also include a tab formed at the distal end and extending distal to the lumen, and a frangible portion extending between the distal end and the proximal end.

Abstract: A device may include a first portion coupled to a shaft of an insertable medical device. The first portion may extend along a first portion longitudinal axis between a proximal end and a distal end. The first portion may include a protrusion extending radially outwardly of the first portion longitudinal axis. At least a portion of the first portion may be received within a lumen of a second portion. The second portion may be axially moveable along the first portion longitudinal axis relative to the first portion. The second portion may include a longitudinally extending channel. A spring may be located radially between the first portion and the second portion.

Abstract: An actuation mechanism for an endoscope is disclosed. The actuation mechanism includes a housing configured to be attached to a handle of the endoscope and a thumbwheel coupled to the housing. Rotation of the thumbwheel causes longitudinal translation of an elongated medical device through a working channel of the endoscope. In some instances, the actuation mechanism includes a drive wheel and/or a roller wheel, wherein the elongate medical device is compressively positioned between the roller wheel and/or the drive wheel. Rotation of the thumbwheel may cause the drive wheel and/or the roller wheel to rotation in opposite rotational directions.

Abstract: An insertion device includes an elongate member and a stylet. The elongate member has a proximal end portion, a distal end portion, and defines a lumen therethrough. The stylet has a distal end portion, a proximal end portion, and is slidably coupled to the elongate member. The stylet is configured to move from a first position to a second position with respect to the elongate member. The distal end portion of the stylet is configured to removably couple a mesh carrier thereto. A portion of the distal end portion of the stylet is disposed outside of the lumen of the elongate member when the stylet is in its first position and is disposed within the lumen when the stylet is in its second position.

Abstract: An adaptor may include a shell and a plunger positioned at a first end of the shell and moveable between an undepressed state and a depressed state. The adaptor may further include a ramp extending from a second end of the shell and a carrier coupled to the ramp. In the undepressed state, the carrier may be located at a first position along the ramp, and wherein, in the depressed state, the carrier may be located at a second position along the ramp, wherein the second position may be closer to the second end of the shell than the first position.

Abstract: A first tubular medical device having a lumen through which a guidewire is insertable and over which the first tubular medical device may be guided to a target site within a patient. The proximal end of the guidewire may be extended into a lumen defined through a second medical device so the second medical device may be guided over the guidewire alongside the first tubular medical device to the target site. The guidewire may be extended into a distal opening in the first tubular medical device and out a side opening of the first tubular medical device to be available for guiding the second medical device alongside the first tubular medical device.

Abstract: An actuation mechanism for an endoscope is disclosed. The actuation mechanism includes a housing configured to be attached to a handle of the endoscope and a thumbwheel coupled to the housing. Rotation of the thumbwheel causes longitudinal translation of an elongated medical device through a working channel of the endoscope. In some instances, the actuation mechanism includes a drive wheel and/or a roller wheel, wherein the elongate medical device is compressively positioned between the roller wheel and/or the drive wheel. Rotation of the thumbwheel may cause the drive wheel and/or the roller wheel to rotation in opposite rotational directions.

Abstract: An insertion device includes an elongate member and a stylet. The elongate member has a proximal end portion, a distal end portion, and defines a lumen therethrough. The stylet has a proximal end portion, a distal end portion, and is slidably coupled to the elongate member. The stylet is configured to move from a first position to a second position with respect to the elongate member. The proximal end portion of the stylet is configured to removably couple a mesh carrier thereto. A portion of the proximal end portion of the stylet is disposed outside of the lumen of the elongate member when the stylet is in its first position and is disposed within the lumen when the stylet is in its second position.

Abstract: In one example, a medical device may be adapted for use with a delivery device, and the medical device may include a handle including at least one actuator; a body adapted to releasably mount to a distal portion of the delivery device, the body supporting a pair of jaws rotatably coupled to the body; and a control wire coupled to the pair of jaws and the actuator. The actuator may be configured to open and close the pair of jaws.

Abstract: Aspects of stone identification methods and systems are described. According to one aspect, an exemplary method comprises: transmitting to a processing unit, with an imaging element mounted on a distal end of a scope, image data about a stone object inside a body cavity; generating from the image data, with the processing unit, a visual representation of the stone object and the body cavity; establishing from a user input, with the processing unit, a scale for the visual representation; determining from the visual representation, with the processing unit, a size of the stone object on the scale; comparing, with the processing unit, the size of the stone object with a predetermined maximum size to determine a removal status; and augmenting, with the processing unit, the visual representation to include an indicator responsive to the removal status. Associated systems are also described.

Abstract: A medical device, comprising a fastening assembly, wherein the fastening assembly includes an adapter defining an opening therethrough, a fastener releasably coupled to the adapter, wherein the fastener includes at least two jaws pivotable relative to one another, the fastener having a first configuration wherein the jaws are open and a second configuration wherein the jaws are closed, and at least one cable coupled to the fastener and the adapter, the at least one cable being configured to apply tension to the fastener to transition between the first configuration and the second configuration while the fastener is coupled to the adapter, and to control release of the fastener from the adapter.

Abstract: An endoscopic device includes a handle body operatively couplable to a shaft housing. The handle body includes an actuator for controlling a distal end of an endoscopic shaft extending from the shaft housing. The device also includes a pull wire attachment configured to operatively couple to a pull wire extending through the shaft housing and the endoscopic shaft to the distal end. Applying tension to the pull wire deflects the distal end of the endoscopic shaft. In addition, the device includes a pulling mechanism coupled to the actuator and having the pull wire attachment extending therefrom. When the pull wire attachment is operatively coupled to the pull wire, actuation of the actuator applies tension to the pull wire and deflects the distal end of the endoscopic shaft.

Abstract: A retrieval device attachable to a scope includes a handle which has an attachment portion configured to couple the handle to the scope; a shaft coupled to the handle having a wire immovably coupled to the handle; and a sheath movable relative to the handle over the wire between a distal position and a proximal position via an actuator of the handle. The actuator actuates a slider assembly of the handle. The slider assembly is coupled to the sheath and movable relative to the attachment portion to move the sheath and an expandable end effector coupled to the distal end of the wire. The end effector is movable between a collapsed configuration when the sheath is moved distally to the distal position to cover the end effector and an expanded configuration when the sheath is moved proximally to the proximal position, uncovering the end effector.