Patents by Inventor Michael Schwarm

Michael Schwarm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of producing optically active pyrrolidines with high enantiomeric purity
    Patent number: 5585500
    Abstract: A method of producing optically active pyrrolidines of the general formula ##STR1## in which R.sup.1 is hydrogen or OH,R.sup.2 is a benzyl group which can have one or more alkyl-, alkoxy- and/or halogen substituents on the aromatic, and* is and/or can be an asymmetric center,by reducing the corresponding, enantiomerically pure pyrrolidinediones using activated alkali boron hydride.
    Type: Grant
    Filed: July 17, 1995
    Date of Patent: December 17, 1996
    Assignee: Degussa Aktiengesellschaft
    Inventors: Karlheinz Drauz, Matthias Kottenhahn, Michael Kraft, Michael Schwarm
  • Method of producing optically active 1,3-imidazolidine-4-ones
    Patent number: 5386035
    Abstract: 2.2. 1,3-imidazolidine-4-ones having the General Formula: ##STR1## are obtained in a pure form especially by means of precipitation, in which production an optically active acid can be used at 0.5-0.8 eq. for the separation of racemates. The non-desired enantiomer can be racemized in an inert solvent and the cyclization to imidazolidinone can take place by means of the optically active acid, whereupon the separation of racemates takes place directly thereafter. 1,3-imidazolidine-4-ones are valuable educts for the preparation of branched or unbranched, proteinogenic or non-proteinogenic .alpha.-amino acids by means of diastereoselective alkylation and subsequent ring splitting.
    Type: Grant
    Filed: November 12, 1992
    Date of Patent: January 31, 1995
    Assignee: Degussa Aktiengesellschaft
    Inventors: Dieter Seebach, Karlheinz Drauz, Matthias Kottenhahn, Hermann Lotter, Michael Schwarm