Abstract: Host nucleic acids and host proteins that participate in viral infection, such as human immunodeficiency virus (HIV), influenza A, and Ebola virus, have been identified. Interfering with or disrupting the interaction between a host nucleic acid or host protein and a virus or viral protein confers an inhibition of or resistance to infection. Thus, interfering with such an interaction in a host subject can confer a therapeutic or prophylactic effect against a virus. The sequences identified can be used to identify agents that reduce or inhibit viral infection.

Abstract: A fiber optic sensor assembly capable of deployment down an instrumentation tube located in a well bore, including a flexible protective tube having a lumen encasing an optical fiber having a core portion and a cladding portion disposed within the flexible tube. The flexible protective tube protects the optical fiber from the oil, water or hydrogen gas within the well bore. A method of deploying the optical fiber down the well bore, is also provided. An optical fiber having a core and a cladding surrounded by the flexible protective tubing is deployed into the lumen of a tube disposed within the well bore by pumping a high pressure fluid into the lumen of the tube, thereby causing the deployment of the optical fiber down the well bore. The protective tubing is impermeable of hydrogen and other corrosive materials.

Abstract: A system and method for deploying and/or retrieving a cable underwater. In an embodiment, a system comprises a cage, comprising a guidance system adapted to be remotely operable subsea by a vessel; a communications link operatively linking the guidance system and the vessel; and a non-palletized reel rotatably and removably mounted within the cage, the reel adapted to receive an unspoolable length of cable, the cable comprising two fee ends. In an exemplary method, the reel, onto which cable is spooled is removably and rotatably housed in a cage adapted for remote control use underwater and the cage lowered by a vessel to a position proximate a seafloor. The cage is maneuvered along a predefined flight pattern in substantially a single plane with respect to the seafloor while selectively releasing the cable from the reel.

Abstract: A dynamic content security parser (DCSP) that provides hardware assisted parallel processing technology for servicing complex web service security transactions at a high rate of throughput as an embeddable software product having a core DCSP engine that utilizes a content security policy to process documents in order to provide digital signature services, content encryption, XML filtering and SAML generation.

Abstract: To achieve a large thickness of conductive metal-containing material in a feature of a product unit processed with a liquid-based etch process, the desired thickness of material is apportioned to the two opposing surfaces of a substrate to create a two-part feature. Conventional features are made by identically patterning two same-thickness metal-containing layers and electrically connecting the resulting patterned parts in any suitable manner. However, features may also be made that do not have identical parts on opposite sides of the substrate, the two parts being electrically connected but differing in thickness, in shape, or both Moreover, having two metal-containing layers separated by an insulator is also useful for allowing different sections of the same feature or circuit to cross one another without shorting, or to overlap in whole or in part without shorting.

Abstract: A digitally controlled angle noise signal generator for generating a signal with precise and accurate noise. The signal generator is formed of a digital noise generator for generating a digital noise signal &thgr;N, and a digital signal generator for forming an internal signal S. The digital signal generator receives the digital noise signal &phgr;N and modulates the internal signal S with the digital noise signal &phgr;N to generate a digitally controlled signal yg=S{&thgr;N}, where is the modulation operator, with precise and accurate noise.

Abstract: A digitally controlled angle noise signal generator for generating a signal with precise and accurate noise. The signal generator is formed of a digital noise generator for generating a digital noise signal &thgr;N, and a digital signal generator for forming an internal signal S. The digital signal generator receives the digital noise signal &phgr;N and modulates the internal signal S with the digital noise signal &phgr;N to generate a digitally controlled signal yg=S{&thgr;N}, where is the modulation operator, with precise and accurate noise.

Abstract: The invention provides for processing of data to determine the likelihood of default of an entity. The processing may comprise obtaining a data set relating to an entity, the data set including at least a first likelihood of default indicator (LDI) value and a second LDI value; determining a LDI rate of change, based on the first LDI value and the second LDI value, to provide a LDI slope value; and determining the likelihood of default of the entity based on the LDI slope value and the first LDI value.

Abstract: A power amplifier circuit (30, 60) improves the linearity of an amplified output signal. The power amplifier circuit (30, 60) includes an input (33, 63) for receiving a carrier signal (34, 64) and an array of combined amplifiers (32, 62) of a predetermined type for amplifying the carrier signal (34, 64). At least one amplifier (48, 78) of the predetermined type is located between the input (33, 63) and the array of combined amplifiers (32, 62) for amplifying the carrier signal (34, 64) to produce a predistorted carrier signal (34b1, 64b1) with a carrier signal component and a distortion component to condition the carrier signal (34, 64) for input into the array of combined amplifiers (32, 62), and specifically to compensate for nonlinearities produced by the array of combined amplifiers (32, 62).

Abstract: A power amplifier circuit (30, 60) improves the linearity of an amplified output signal. The power amplifier circuit (30, 60) includes an input (33, 63) for receiving a carrier signal (34, 64) and an array of combined amplifiers (32, 62) of a predetermined type for amplifying the carrier signal (34, 64). At least one amplifier (48, 78) of the predetermined type is located between the input (33, 63) and the array of combined amplifiers (32, 62) for amplifying the carrier signal (34, 64) to produce a predistorted carrier signal (34b1, 64b1) with a carrier signal component and a distortion component to condition the carrier signal (34, 64) for input into the array of combined amplifiers (32, 62), and specifically to compensate for nonlinearities produced by the array of combined amplifiers (32, 62).

Abstract: Cell based screens for studying drug transport are described and improved methods for the preparation of cell monolayers for use in such screens are disclosed.

Abstract: Apparatus for identifying wireless subscriber units and for determining if access to a communications network should be granted. A plurality of wireless subscriber units each generates a wireless subscriber signal including internal data traits and external signal traits. The internal data traits include an identification code. A RF downconverter is located remote from the wireless subscriber units and receives the wireless subscriber signal. A characterizing device is connected to the RF downconverter and extracts parameters that characterize the external signal traits of the wireless subscriber units. A decision device computes the likelihood that the observed parameters belong to the validated wireless subscriber unit to determine if access to the wireless subscriber service should be granted. The apparatus may be used to prevent cellular telephone cloning fraud.

Abstract: Validating identification clusters formed of unique transmitter intercepts and validating clusters based on information within the cluster data with or without the aid of specific intercepts. Transmitter validation signals are allocated for validating specific ones of the transmitters. Analyzers identify specific received intercepts from specific ones of the transmitters to form an identification signal. Storage is provide for storing the specific received intercepts with corresponding identification clusters for marking the specific identification cluster as validated or invalidated. The valid and invalid states of the stored clusters are used to authorize or prevent access by the transmitters to the communication system.

Abstract: The present invention is directed to an apparatus and method for safely transporting mobility devices on the rear of a motor vehicle. The apparatus and method includes wheel wells to receive the drive wheels of the mobility device, and L-shaped members which automatically retain the undercarriage of the mobility device when it is being lifted into position for transport and which automatically disengage from the undercarriage when the mobility device is being lowered to the ground for unloading.

Abstract: A dimpled golf ball is provided with a regular repeating dimple pattern by projecting on to the surface of the ball the edges of a regular octahedron, thereby forming eight equilateral triangles on the surface. Each of the eight equilateral triangles can then be divided into sub-triangles so that there are four, six, seven or nine dimple-free great circles on the ball.

Abstract: An X-ray contrast composition comprising particles consisting essentially of a non-radioactive crystalline organic x-ray contrast agent having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than 400 nm, and a pharmaceutically acceptable carrier therefor is useful in x-ray diagnostic medical imaging methods. The agents can be delivered to a specific tissue or fluid site, for example, the blood pool, liver or spleen. In one embodiment involving intravenous administration, preferred compositions provide effective imaging of the blood pool for remarkably long times.

Abstract: In a set of golf iron heads, at least part of the striking face of each head is of a material selected for characteristics desired for the particular iron in the set, and at least some of the heads are multi-component heads in which at least part of the striking face area of the head comprises at least one face-piece component of material having at least one characteristic different from the rest of the head.There is also provided a multi-component golf iron head in which at least part of the striking face area of the head comprises at least one face-piece component, the face-piece component being: (a) of material selected for its surface friction and/or flexural modulus characteristics affecting the spin behavior of golf balls when struck by the head, and/or (b) of specific gravity and/or geometric configuration selected to contribute to the desired weight distribution in the head.

Abstract: In a set of golf iron heads, one of the components for each of the heads is a face-piece forming at least a portion of a striking face of the head, the thickness of the face-piece increasing from the toe to the heel of the head in at least one iron of the set and increasing from the heel to the toe of the head in at least one other iron of the set. Alternatively, the thickness of the face-piece increases from the top edge to the sole in at least one head of the set, and increases from the sole to the top edge in at least one other head of the set.

Abstract: An X-ray contrast composition comprising particles consisting essentially of a non-radioactive crystalline organic x-ray contrast agent having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than 400 nm, and a pharmaceutically acceptable carrier therefor is useful in x-ray diagnostic medical imaging methods. The agents can be delivered to a specific tissue or fluid site, for example, the blood pool, liver or spleen. In one embodiment involving intravenous administration, preferred compositions provide effective imaging of the blood pool for remarkably long times.