Abstract: A traffic control system is disclosed as having a locating device configured to generate a location signal indicative of a location of each of a plurality of machines. The traffic control system may also have an onboard controller configured to regulate operation of the plurality of machines based on the location signal, a communication device, and a worksite controller. The worksite controller may be configured to determine a first route for a first of the plurality of machines, and to determine if a first lane of the first route is blocked by a second of the plurality of machines. The worksite controller may also be configured to determine if a second lane of the first route intersects with a second route of the second of the plurality of machines, and to selectively grant permission for travel of the first of the plurality of machines through the second lane.

Abstract: In one embodiment, a medicament system configured to communicate information about a medicament device or about a use of a medicament device, or a combination thereof, to a user, is provided.

Abstract: A resettable injection training device having an outer shell including a proximal end and a distal end, the outer shell defining a chamber there within, an actuation member near a proximal end, and a plunger slidable within the chamber is provided in an embodiment herein. The embodiment further including a safety shield having an extended locked position, an extended unlocked position and a retracted position, a locking sleeve configured to interact with the safety shield, and a reset shuttle disposed within the safety shield at a distal end of the device, wherein the reset shuttle is slidable relative to the safety shield, such that movement of the reset shuttle toward the proximal end of the device unlocks the safety shield.

Abstract: Apparatus and methods for delivery of an implant at a target site in an interior of a bone. The apparatus may include a plate. The plate may include a bottom surface complementing a surface contour of a bone. The plate may define first holes sized for receiving screws. The plate may define second holes sized for receiving fixation elements. The plate may define an opening. The opening may be sized for providing passage of the implant through the plate. When the bottom surface is seated complementarily against the surface contour, the first holes may point into an interior of the bone and into a volume occupied by the implant in the interior when the implant is positioned at a target site and radially expanded to form a mesh cage.

Abstract: In one embodiment, a resettable injection training device is provided herein. The injection training device includes an outer shell comprising a proximal end and a distal end, the outer shell defining a chamber there within, and a plunger slidable within the chamber, the plunger comprising a plunger feature and one or more rail portions. The injection training device further includes a locking safety shield disposed and slidable within the chamber, the safety shield comprising a proximal end and a distal end, the distal end for interfacing with a target surface to actuate the injection training device, the safety shield comprising an extended locked position, an extended unlocked position, and a retracted position.

Abstract: Embodiments of a resettable injection training device are provided herein. The resettable injection training device includes a body and a retractable shield, extendable and retractable relative to the body of the device, in an embodiment. In another embodiment, the resettable injection training device may include an injection simulation member. The retractable shield may be lockable in an extended position, and may be unlocked to retract the shield for a subsequent use of the device in one non-limiting embodiment. In another non-limiting embodiment, a resetting component may be used to retract the shield to reset the device.

Abstract: In one embodiment, a medicament system configured to communicate information about a medicament device or about a use of a medicament device, or a combination thereof, to a user, is provided.

Abstract: A traffic control system is disclosed as having a locating device configured to generate a location signal indicative of a location of each of a plurality of machines. The traffic control system may also have an onboard controller configured to regulate operation of the plurality of machines based on the location signal, a communication device, and a worksite controller. The worksite controller may be configured to determine a first route for a first of the plurality of machines, and to determine if a first lane of the first route is blocked by a second of the plurality of machines. The worksite controller may also be configured to determine if a second lane of the first route intersects with a second route of the second of the plurality of machines, and to selectively grant permission for travel of the first of the plurality of machines through the second lane.

Abstract: A composition comprising a source of metal ions and at least one leveling agent comprising a linear or branched, polymeric imidazolium compound comprising the structural unit of formula L1 (L1) wherein R1, R2, R3 are each independently selected from an H atom and an organic radical having from 1 to 20 carbon atoms, R4 is a divalent, trivalent or mutlivalent organic radical which does not comprise a hydroxyl group in the a or ? position relative to the nitrogen atom of the imidazole rings is an integer.

Abstract: In an embodiment, a resettable shield-activated injection training device is provided. The training device includes an outer housing comprising a proximal end and a distal end, an inner housing comprising a proximal end and a distal end, plunger retention protrusions near the proximal end, and an asymmetrical projection at the distal end.

Abstract: A container for delivering a medicament to a target location includes a housing having a proximal end and a distal end, the housing including a cap locking tab at the distal end, and a vial containing medicament. The container includes a plunger slidable within the vial from the proximal end to the distal end of the vial to dispel the medicament, an injection member associated with the distal end, such that medicament dispelled from the vial passes through the injection member to the target location, and a slidable interaction member associated with the distal end of the vial configured to slide with the vial. An interaction between the slidable interaction member and cap locking tab causes the cap locking tabs to bias outward, and placement of a safety cap on the container after use locks the safety cap onto the container via the interaction with the cap locking tabs.

Abstract: A resettable injection training device having a an outer shell including a proximal end and a distal end, the outer shell defining a chamber there within, an actuation member near a proximal end, and a plunger slidable within the chamber is provided. The device further including a safety shield having an extended locked position, an extended unlocked position and a retracted position, a locking sleeve configured to interact with the safety shield, and a reset shuttle disposed within the safety shield at a distal end of the device, wherein the reset shuttle is slidable relative to the safety shield, such that movement of the reset shuttle toward the proximal end of the device unlocks the safety shield.

Abstract: Method of lightening the color of mixtures comprising imidazolium salts or imidazoles, wherein the mixtures are treated with an oxidant.

Abstract: In an embodiment, a medicament delivery system is provided. The medicament delivery system includes a container for storing a medicament prior to use, the container having a first end and a second end, an injection member in fluid communication with the container, an actuation mechanism associated with the container and configured to deliver the medicament from the container through the injection member when the actuation mechanism is activated. The medicament delivery system further includes at least one detection element associated with the system, wherein in a first mode of operation of the system, medicament is delivered through the injection member and in a second mode of operation of the system, medicament is not delivered through the injection member, and the mode of operation is dependent on an output from the at least one detection element.

Abstract: Embodiments of a resettable injection training device are provided herein. The resettable injection training device includes a body and a retractable shield, extendable and retractable relative to the body of the device, in an embodiment. In another embodiment, the resettable injection training device may include an injection simulation member. The retractable shield may be lockable in an extended position, and may be unlocked to retract the shield for a subsequent use of the device in one non-limiting embodiment. In another non-limiting embodiment, a resetting component may be used to retract the shield to reset the device.

Abstract: In an embodiment, a positioning apparatus for guiding an injection device relative to a target surface having a representative plane is provided. The apparatus includes a housing defining a channel configured to receive an injection device, wherein a first angle is formed between a longitudinal axis of the channel and the representative plane of the target surface so as to guide the injection device through the channel to the target surface at the first angle, and wherein the housing comprises a stabilizing surface configured to abut the target surface to stabilize an injection according to the first angle.

Abstract: In an embodiment, an injection training device configured to interact with an injection device having an injection member is provided herein. The injection training device includes a housing having an opening, a pad component disposed in the opening, wherein the pad component is configured to receive an injection member of an injection device. The injection training device further includes a signal output component and circuitry associated with the housing to receive information about the operation of the injection device and to provide a communication about an operation of the injection device to a user of the injection training device through the signal output component.

Abstract: A process for the preparation of the ether of formula I where R1 and R2 independently from one another are hydrogen or an alkyl group with 1 to 10 C atoms, R3 is an alkyl group with 1 to 10 carbon atoms and X is a bond or a hydrocarbon group with 1 to 10 carbon atoms comprising a) deprotonating the amino alcohol of formula II where R1, R2 and X have the meaning above with a metal as deprotonating agent to give the anion of formula III where R1, R2 and X have the meaning above and b) alkylation of the anion obtained in step a) with an alkylation agent to give the ether of formula I.

Abstract: In an embodiment, a respiratory inhaler training device configured to provide stepwise instructions for using the device to a user in a sequence of steps is provided. The respiratory inhaler training device includes a housing defining a channel with an inlet and an outlet, at least one actuation mechanism simulating provision of medicament, at least one fluid flow rate sensor positioned so as to detect a rate of fluid flow through the channel to determine a fluid flow rate, a signal output component for providing an output, a microprocessor and a timekeeping component, a storage medium component associated with the microprocessor comprising a database of instructions pertaining to the sequence and/or timing of steps for using the device stored thereon.

Abstract: Embodiments of a respiratory inhaler training device to provide stepwise instructions for using the device to a user in a sequence of steps are provided herein.