Abstract: An atomizing spray nozzle device includes plural inlets that receive different phases of materials of a coating. The device also includes an atomizing zone housing portion fluidly coupled with the inlets and shaped to mix the different phases of the materials into a mixed phase slurry. The device also includes a plenum housing portion fluidly coupled with the atomizing housing portion along the center axis of the device. The plenum housing portion includes an interior plenum that is elongated along the center axis of the device. The plenum is configured to receive the mixed phase slurry from the atomizing zone. The device also includes one or more delivery nozzles fluidly coupled with the plenum. The one or more delivery nozzles provide one or more outlets from which the mixed phase slurry is delivered onto one or more surfaces of a target object as a coating on the target object.

Abstract: A motor driven propulsor of an aircraft includes magnets disposed in fan shrouds of fan blades connected with a fan hub, a stator having individual conductive coils in a nacelle located radially outside of the fan hub, and a distributed inverter assembly having several inverter power stages and gate drivers, each of the inverter power stages coupled with a separate gate driver of the gate drivers and a separate coil of the coils in the stator. Each of the gate drivers is configured to individually control supply of direct current to the corresponding inverter power stage. Each of the inverter power stages is configured to convert the direct current supplied to the inverter power stage to an alternating current that is supplied to the corresponding coil in the stator to rotate the magnets and the fan blades around a center line of the fan hub for propelling the aircraft.

Abstract: The present disclosure provides particles with a polymeric core containing a pharmaceutically active agent; and an antibody fragment conjugated to the surface of the particle, wherein the antibody fragment targets an endogenous immune cell subset (e.g., an endogenous T-cell or a myeloid-derived suppressor cell). The present invention provides methods for forming and methods for using the particles. The particles described herein may be useful in treating and/or preventing proliferative disease, inflammatory disease, or neoplastic disorders (e.g., cancer, autoimmune diseases). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a particle described herein.

Abstract: Method, systems, crosspoint arrays, and systems for tuning a neural network. A crosspoint array includes: a set of conductive rows, a set of conductive columns intersecting the set of conductive rows to form a plurality of crosspoints, a circuit element coupled to each of the plurality of crosspoints configured to store a weight of the neural network, a voltage source associated with each conductive row, a first integrator attached at the end of at least one of the conductive column, and a first variable resistor attached to the integrator and the end of the at least one conductive column.

Abstract: Provided are drug delivery compositions and devices useful for the treatment and/or prevention of cancer and metastatic tumors. For example, a drug delivery device is provided that comprises a biodegradable scaffold carrying one or more anti-cancer therapeutic agents that activate the innate immune system (e.g., STING agonists) and/or the adaptive immune system (e.g., anti-PD-1 antibodies). The compositions and devices may include a cytokine (e.g., IL-15 superagonist). The drug delivery device can be implanted in the void volume of a resected tumor to prevent tumor regrowth and tumor metastasis. Also provided are methods of making the drug delivery compositions and devices as well as kits containing materials to provide the compositions and devices.

Abstract: The described embodiments provide thermal energy via solar powered heat exchangers. This energy can be implemented to heat hot water or heat residential/commercial structures. Parallel mounted vacuum insulated tubes heat water within a geometric heat transfer piping system. This thermal energy is transferred via a piping system to an insulated tank. A digital controller monitors and controls the temperature of the water within the system as well as provides frost/freezing protection. An electrical active pumping system is connected to the digital controller to circulate water within the solar heat exchanger. The electric active pump can be connected to a solar photovoltaic (electric) panel for reliable and uninterrupted heat/hot water delivery.

Abstract: Provided are drug delivery compositions and devices useful for the treatment and/or prevention of cancer and metastatic tumors. For example, a drug delivery device is provided that comprises a biodegradable scaffold carrying one or more anti-cancer therapeutic agents that activate the innate immune system (e.g., STING agonists) and/or the adaptive immune system (e.g., anti-PD-1 antibodies). The compositions and devices may include a cytokine (e.g., IL-15 superagonist). The drug delivery device can be implanted in the void volume of a resected tumor to prevent tumor regrowth and tumor metastasis. Also provided are methods of making the drug delivery compositions and devices as well as kits containing materials to provide the compositions and devices.

Abstract: An atomizing spray nozzle device includes an atomizing zone housing that receives different phases of materials used to form a coating. The atomizing zone housing mixes the different phases of the materials into a two-phase mixture of ceramic-liquid droplets in a carrier gas. The device also includes a plenum housing fluidly coupled with the atomizing housing and extending from the atomizing housing to a delivery end. The plenum housing includes an interior plenum that receives the two-phase mixture of ceramic-liquid droplets in the carrier gas from the atomizing zone housing. The device also includes one or more delivery nozzles fluidly coupled with the plenum chamber. The delivery nozzles provide outlets from which the two-phase mixture of ceramic-liquid droplets in the carrier gas is delivered onto one or more surfaces of a target object as the coating on the target object.

Abstract: Provided are drug delivery compositions and devices useful for the treatment and/or prevention of cancer and metastatic tumors. For example, a drug delivery device is provided that comprises a biodegradable scaffold carrying one or more anti-cancer therapeutic agents that activate the innate immune system (e.g., STING agonists) and/or the adaptive immune system (e.g., anti-PD-1 antibodies). The compositions and devices may include a cytokine (e.g., IL-15 superagonist). The drug delivery device can be implanted in the void volume of a resected tumor to prevent tumor regrowth and tumor metastasis. Also provided are methods of making the drug delivery compositions and devices as well as kits containing materials to provide the compositions and devices.

Abstract: According to some embodiments, a lossless protection procedure may be applied to control distribution of a print geometry of an industrial asset item. For example, an item definition data store may contain electronic records defining a geometry of the industrial asset item. A signature identifier encoder platform may determine a unique signature identifier associated with the industrial asset item and modify the geometry of the industrial asset item to encode therein information about the unique signature identifier. In some cases, for example, this may be done by adjusting a scanning pattern of a fill region (e.g., stripe, checkerboard, etc.) or a support structure of the industrial asset item. An authentication platform may then receive, from a sensor (e.g., an X-ray), a measured characteristic parameter of an item to be authenticated and determine a signature identifier of the item (which can be used to authenticate the item).

Abstract: Provided are drug delivery compositions and devices useful for the treatment and/or prevention of cancer and metastatic tumors. For example, a drug delivery device is provided that comprises a biodegradable scaffold carrying one or more anti-cancer therapeutic agents that activate the innate immune system (e.g., STING agonists) and/or the adaptive immune system (e.g., anti-PD-1 antibodies). The compositions and devices may include a cytokine (e.g., IL-15 superagonist). The drug delivery device can be implanted in the void volume of a resected tumor to prevent tumor regrowth and tumor metastasis. Also provided are methods of making the drug delivery compositions and devices as well as kits containing materials to provide the compositions and devices.

Abstract: A processing unit, including a first circuit part, and a capacitor connected to the first circuit part. The capacitor is charged or discharged by the first circuit part.

Abstract: A coated component including a slotted ceramic coating with a reactive phase coating disposed thereon for improved resistance to environmental contaminant compositions, along with methods of its formation, is provided. The coated component may include a substrate defining a surface, a ceramic coating disposed on the surface of the substrate, and a reactive phase coating disposed on the layer of environmental contaminant compositions. The ceramic coating includes a plurality of slots disposed in the ceramic coating forming segments of ceramic coating material.

Abstract: Provided are drug delivery compositions and devices useful for the treatment and/or prevention of cancer and metastatic tumors. For example, a drug delivery device is provided that comprises a biodegradable scaffold carrying one or more anti-cancer therapeutic agents that activate the innate immune system (e.g., STING agonists) and/or the adaptive immune system (e.g., anti-PD-1 antibodies). The compositions and devices may include a cytokine (e.g., IL-15 superagonist). The drug delivery device can be implanted in the void volume of a resected tumor to prevent tumor regrowth and tumor metastasis. Also provided are methods of making the drug delivery compositions and devices as well as kits containing materials to provide the compositions and devices.

Abstract: An atomizing spray nozzle device includes plural inlets that receive different phases of materials of a coating. The device also includes an atomizing zone housing portion fluidly coupled with the inlets and shaped to mix the different phases of the materials into a mixed phase slurry. The device also includes a plenum housing portion fluidly coupled with the atomizing housing portion along the center axis of the device. The plenum housing portion includes an interior plenum that is elongated along the center axis of the device. The plenum is configured to receive the mixed phase slurry from the atomizing zone. The device also includes one or more delivery nozzles fluidly coupled with the plenum. The one or more delivery nozzles provide one or more outlets from which the mixed phase slurry is delivered onto one or more surfaces of a target object as a coating on the target object.

Abstract: An atomizing spray nozzle device includes an atomizing zone housing that receives different phases of materials used to form a coating. The atomizing zone housing mixes the different phases of the materials into a two-phase mixture of ceramic-liquid droplets in a carrier gas. The device also includes a plenum housing fluidly coupled with the atomizing housing and extending from the atomizing housing to a delivery end. The plenum housing includes an interior plenum that receives the two-phase mixture of ceramic-liquid droplets in the carrier gas from the atomizing zone housing. The device also includes one or more delivery nozzles fluidly coupled with the plenum chamber. The delivery nozzles provide outlets from which the two-phase mixture of ceramic-liquid droplets in the carrier gas is delivered onto one or more surfaces of a target object as the coating on the target object.

Abstract: A processing unit includes a circuit including a current mirror, and a capacitor providing a weight based on a charge level of the capacitor. The capacitor is charged or discharged by the current mirror.

Abstract: A vertical injection punchthrough based metal oxide semiconductor (VIPMOS) device and method of manufacturing the same, include a control gate, an erase gate, a floating gate, and an active area where the control gate, the erase gate, and the floating gate are coplanar and perpendicular to the active area.

Abstract: A virtual aerodynamic component for a wind turbine including at least one rotor blade connected to a hub. The at least one rotor blade defines an inner portion and a profiled outer portion. The virtual aerodynamic component includes one or more air-blowing units configured to provide a flow of air substantially opposed to an incoming wind. The flow of air defines the virtual aerodynamic component in front of the inner portion of the at least one rotor blade and provides for redirection of the incoming wind toward the profiled outer portion of the at least one rotor blade in an operational state and allows the incoming wind to flow toward the inner portion of the at least one rotor blade in a non-operational state. Further described is a wind turbine including the above-described virtual aerodynamic component and method for aerodynamic performance enhancement of an existing wind turbine.

Abstract: Provided are drug delivery compositions and devices useful for the treatment and/or prevention of cancer and metastatic tumors. For example, a drug delivery device is provided that comprises a biodegradable scaffold carrying one or more anti-cancer therapeutic agents that activate the innate immune system (e.g., STING agonists) and/or the adaptive immune system (e.g., anti-PD-1 antibodies). The compositions and devices may include a cytokine (e.g., IL-15 superagonist). The drug delivery device can be implanted in the void volume of a resected tumor to prevent tumor regrowth and tumor metastasis. Also provided are methods of making the drug delivery compositions and devices as well as kits containing materials to provide the compositions and devices.