Abstract: Numerous applications for hollow glass bodies made from low melting glass material require an increase in the chemical resistance of the interior surface of the glass body. In order to avoid a disadvantageous de-alkalizing process the hollow glass body must be provided with an interior coating in a comparatively expensive prior art process. In an improved process according to the invention a glass tube acting as a semifinished product from which the hollow glass body is made is provided with an interior coating of oxide material, preferably SiO2, Al2O3, TiO2 or mixtures thereof, having a predetermined coating thickness according to the required chemical resistance or working conditions for forming the glass body and then the hollow glass body is made from the glass tube. The coating is advantageously provided by means of a PICVD process.

Abstract: The invention is a glass container which can be sterilized for medical purposes, including the storage of pharmaceutical or diagnostic products, further including solutions. The container is made from glass containing a stabilizer which inhibits the deleterious effects of high energy radiation, wherein the surface which is in direct contact with the product or solution has a coating that has a thickness of less than 400 nm and is formed from oxides or nitrides of the elements Si, Ti, Ta, AI or a mixture thereof.

Abstract: In order to guarantee that individual elastomeric components used for medicinal or pharmaceutical purposes have improved inertness and static and sliding friction properties, a suitable layer is provided on the elastomeric components for this purpose by the method of the invention. This method includes providing an extended flat mat made of elastomeric material including connected protruding elastomeric components; coating at least one side of the mat including the connected elastomeric components by means of a PECVD or PICVD method to provide a silicon dioxide layer containing carbon, hydrogen and/or nitrogen on the at least one side of the mat; and punching the connected elastomeric components out of the mat to form individual unconnected elastomeric components, each at least partially coated with a portion of the layer.

Abstract: Medical cannulas are typically provided with a silicone coating to improve incision performance. In order to produce a thin, continuous and even coating layer, silicone oil is provided at one side of an elastic foil and the foil is penetrated by the uncoated cannula from an opposite side. During this operation the cannula is wetted by the silicone oil. During withdrawal of the cannula from the foil, excess silicone oil is removed from the cannula and an even, particle-free thin coating which has no bulge- or bead-forming tendency during incision is obtained. Subsequently, the silicone coating is dried.

Abstract: A method for manufacturing a filled syringe body within a single continuous manufacturing line in a self-contained environment with controlled conditions. The method includes the steps of injection molding the syringe body, sealing the one end of the syringe body, siliconizing the barrel of the syringe body, filling it, sealing the other end of the syringe, and sterilizing it. With this new "injection mold-fill-seal" method, a syringe body can be manufactured as a mass-produced article in one manufacturing line in an inexpensive manner.

Abstract: A glass bottle (1) fitted with a narrowed neck (2) which can be filled under pressure with chiefly a medically active substance sprayable by aerosol and with a propellant and which exhibits an opening which may be closed using a dosage valve (5). This glass bottle (1) has a sprayed-on synthetic coating (4) to protect it against shattering and splintering, preventing the user from being injured by the broken bottle. To substantially enhance this safety, the neck (2) of the bottle (1) has been fitted with a bulge like edge (3) at the opening which is also coated with the synthetic material (4) and onto which the dosage valve (5) is mechanically attached by turning. Furthermore, the coating (4) consists of an elastic synthetic material with pronounced increased shrinkage properties used for the summoning of pre-stressing force on the glass body (1) and it exhibits several hole-like pressure relieving openings (7) permitting rapid pressure release in case of shattering.

Abstract: The pre-filled single-use hypodermic devices must be provided with a needle cap device (1) during storage for protection of the injector needle (4) and the contents of the hypodermic device which is removed prior to use. The two-part needle cap device (1) includes a plastic outer casing (5) of hard elastic transparent material which is provided inside with a lining member (6) sealing the tip of the injector needle and made from a soft elastic material. The injector head (2) and the plastic outer casing (5) have a coupling device for making a mechanical stable form-fitting connection and/or a positive-locking connection with a reliable microbiological seal when the injector head (2) is inserted in the outer casing (5). This coupling device is formed by elements on or features of the injector head (2) and outer casing (5).

Abstract: A plastic vessel has a barrier coating comprising sequentially arranged barrier layers of organic polymer and of inorganic oxides, nitrides or oxynitrides. The barrier coating preferably has at least two inorganic barrier layers. The thickness of the inorganic barrier layers lies between 2 and 300 nm and the thickness of the organic barrier layer lies between 2 and 1000 nm. The total thickness of the layer packet should not exceed 0.1 mm.

Abstract: A gripping strip for prefilled disposable syringes having a syringe cylinder. The gripping strip has a gripping strip element formed as a separate synthetic plastic part fixedly mountable on the syringe cylinder, a plate-shaped abutment provided on the gripping strip element and having a hollow cylindrical receptacle with an outer diameter which is adapted to be smaller than an inner diameter of the syringe cylinder, arresting elements provided in a region of an outer surface of the gripping strip element for mounting with the syringe cylinder in a complimentary inner undercut of the syringe cylinder, a safety ring insertable in an interior of the receptacle for maintaining a working connection, the safety ring being connected with the interior of the receptacle of one piece through locations of desired breakage in an unsecured position, so that during placing the syringe cylinder over the receptacle it is displaceable into a securing position.

Abstract: The invention relates to a device for administering substances at overpressure. The device includes a pressure vessel made of glass and containing a substance to be discharged from the pressure vessel and at least one propellent. The pressure vessel has an opening and an actuable discharge element mounted on the pressure vessel in the opening for releasing the substance from the pressure vessel. A self-supporting housing encloses the pressure vessel and at least a portion of the discharge element to prevent splinters of glass and the discharge element from being propelled away from the device in the event that the pressure vessel bursts. The self-supporting housing has a lower portion made of transparent plastic to facilitate viewing the substance in the pressure vessel.

Abstract: A fully assembled dual chamber prefillable syringe cylinder for the administration of two components having a syringe barrel which, in both its single cylinder and dual chamber cylinder embodiments, is connected to both a syringe head featuring a tip cap as well as to the finger grips and which is closed at its base by means of a moveable plunger with a plunger rod and into which an intermediate plunger is positioned with the intent of separating first and second chambers from each other and which features a bypass located in a first chamber, as well as to a method for the manufacture and filling of said fully assembled prefillable syringe.

Abstract: A plastic vessel has a barrier coating comprising sequentially arranged barrier layers of organic polymer and of inorganic oxides, nitrides or oxynitrides. The barrier coating preferably has at least two inorganic barrier layers. The thickness of the inorganic barrier layers lies between 2 and 300 nm and the thickness of the organic barrier layer lies between 2 and 1000 nm. The total thickness of the layer packet should not exceed 0.1 mm.