Abstract: A magnetometer that finds a magnitude of an ambient magnetic field, comprising: a) a diamond cubic structure crystal, with an ensemble of paramagnetic defects oriented along each of the crystal's four tetrahedral axes; b) a microwave source that produces a microwave field at the crystal, of controllable frequency over a range that includes microwave resonance frequencies of paramagnetic defects oriented along all four axes; c) a light source that illuminates the paramagnetic defects with light that causes fluorescent emission from the paramagnetic defects; d) a light detector that measures the fluorescent emission; and e) a controller configured to: 1) measure the fluorescent emission at different microwave frequencies within the range, to obtain a spectrum of the paramagnetic defect ensemble; 2) calculate a variance property of the spectrum; and 3) calculate the magnitude of the ambient magnetic field from the variance property.

Abstract: An example method for quantitative systems pharmacology (QSP) includes analyzing, using a computing device, RNA sequencing (RNA-seq) data for a plurality of patients having a disease. The analysis identifies a plurality of differentially expressed genes (DEGs) and a plurality of differentially enriched biological pathways. Additionally, the method includes deriving, using the computing device, a plurality of gene expression signatures associated with each of a plurality of disease states of the disease using the DEGs and the differentially enriched biological pathways. The method also includes identifying, using the computing device, a plurality of drugs predicted to reverse a particular gene expression signature associated with a particular disease state of the disease. The method further includes prioritizing, using the computing device, the drugs predicted to normalize the particular gene expression signature associated with the particular disease state of the disease for further experimental testing.

Abstract: A system for representing quantum information, such as for storing and processing quantum information, is formed from a chain of quantum objects. The number of quantum objects is at least six, and each quantum object is characterized by a local quantum degree of freedom. A plurality of coupling elements couple the local quantum degrees of freedom of the quantum objects: and the system has at least two quantum mechanical states of different energy. useable for representing information. The strengths of the couplings provided by the coupling elements are such that: (i) the two quantum mechanical states are invariant under the action of a translation operator. the action of the translation operator being to displace each quantum object to a nearest neighbor quantum object: and (ii) the two quantum mechanical states are eigenstates of an inversion operator with opposite eigenvalues. the action of the inversion operator being to invert the quantum objects about a point of symmetry.

Abstract: Disclosed herein are methods of identifying a compound for treating or preventing an infection with an infectious microbe, such as a coronavirus, in a subject in need thereof. Also disclosed herein are compounds and compositions identified by said methods, and methods of use thereof.

Abstract: In various embodiments, hairstyling devices utilize liquid agents for styling, bleaching, coloring, and/or other hair treatments. Leakage of the liquid agents is prevented by use of a vacuum source that removes excess liquid from the device, sufficient liquid for treatment remaining within the device in one or more absorbent pads.

Abstract: A magnetometer that finds a magnitude of an ambient magnetic field, comprising: a) a diamond cubic structure crystal, with an ensemble of paramagnetic defects oriented along each of the crystal's four tetrahedral axes; b) a microwave source that produces a microwave field at the crystal, of controllable frequency over a range that includes microwave resonance frequencies of paramagnetic defects oriented along all four axes; c) a light source that illuminates the paramagnetic defects with light that causes fluorescent emission from the paramagnetic defects; d) a light detector that measures the fluorescent emission; and e) a controller configured to: 1) measure the fluorescent emission at different microwave frequencies within the range, to obtain a spectrum of the paramagnetic defect ensemble; 2) calculate a variance property of the spectrum; and 3) calculate the magnitude of the ambient magnetic field from the variance property.

Abstract: Disclosed are compositions and methods for screening drugs that treat neurodegenerative disorders and methods of treating neurodegenerative orders with combinations of said drugs.

Abstract: Disclosed are compositions and methods for screening drugs that treat neurodegenerative disorders and methods of treating neurodegenerative orders with combinations of said drugs.

Abstract: A nozzle deposits a filament of viscous, molten glass onto a print bed, while the print bed rotates about a vertical axis and translates in x, y, and z directions. The deposition is computer controlled, such that the resulting deposited filament forms a desired glass object that is solid after it anneals. One or more motors rotate the print bed such that the direction of deposition of the molten glass is constant relative to the nozzle, even though the print bed is translating in different directions relative to the nozzle. Keeping the direction of deposition constant relative to the nozzle tends to prevent the extruded filament of molten glass from experiencing large, changing, tensile and shear forces that would otherwise occur and that would otherwise damage the filament.

Abstract: In illustrative implementations of this invention, a crucible kiln heats glass such that the glass becomes or remains molten. A nozzle extrudes the molten glass while one or more actuators actuate movements of the nozzle, a build platform or both. A computer controls these movements such that the extruded molten glass is selectively deposited to form a 3D glass object. The selective deposition of molten glass occurs inside an annealing kiln. The annealing kiln anneals the glass after it is extruded. In some cases, the actuators actuate the crucible kiln and nozzle to move in horizontal x, y directions and actuate the build platform to move in a z-direction. In some cases, fluid flows through a cavity or tubes adjacent to the nozzle tip, in order to cool the nozzle tip and thereby reduce the amount of glass that sticks to the nozzle tip.

Abstract: Methods of image breathing correction. Implementations may include capturing and displaying a first image to a user using a lens, an image sensor, memory, and a display included in a camera unit, adjusting a position of the lens, capturing a second image and storing data of the second image collected by the image sensor in the memory. The method may include determining a second position of the lens using a lens position sensor included in the camera unit and calculating a change in magnification from the first image to the second image using a processor and a breathing correction model. The method may include rescaling the data of the second image to generate corrected second image data using the processor and displaying the corrected second image to a user. The corrected second image may be substantially free from breathing effects when compared with the first image.

Abstract: A switch comprises a first strip conductor and a second strip conductor, arranged orthogonally in a first plane. Moreover, the switch comprises a first switching conductor, having an orthogonally angled shape relative to the first plane. The switch comprises a switching actuator, which is mechanically connected to the first switching conductor and adapted to move vertically relative to the first plane to a first position and to a second position. The switching actuator is configured, so that in the first position, the first strip conductor is in contact with the first switching conductor and the second strip conductor is in contact with the first switching conductor, and so that in the second position, the first strip conductor and the second strip conductor are not in contact with the first switching conductor.

Abstract: A switch comprises a first elastic element, an actuator-element mechanically coupled to a first side of the first elastic element, and a first switching conductor, mechanically coupled to a second side of the first elastic element. The switching conductor is configured for moving between a first conductor position and a second conductor position. The actuator-element is configured from moving between a first actuator-element position and a second actuator-element position separated by a predefined actuator-element lift, thereby moving the first side of the first elastic element. The first elastic element moreover is configured for converting a movement of the first side of the first elastic element by the predefined actuator-element lift into the movement of the second side of the first elastic element with a predefined elastic force.

Abstract: Methods of image breathing correction. Implementations may include capturing and displaying a first image to a user using a lens, an image sensor, memory, and a display included in a camera unit, adjusting a position of the lens, capturing a second image and storing data of the second image collected by the image sensor in the memory. The method may include determining a second position of the lens using a lens position sensor included in the camera unit and calculating a change in magnification from the first image to the second image using a processor and a breathing correction model. The method may include rescaling the data of the second image to generate corrected second image data using the processor and displaying the corrected second image to a user. The corrected second image may be substantially free from breathing effects when compared with the first image.

Abstract: A high frequency switch is provided. The high frequency switch comprises a first high frequency connector, comprising a first inner conductor, integrally formed with a first strip conductor. Moreover, the high frequency switch comprises a second strip conductor arranged orthogonally in a first plane relative to the first strip conductor, a third strip conductor, arranged orthogonally in the first plane relative to the first strip conductor, a first switching conductor, having an orthogonally angled shape relative to the first plane, a second switching conductor, having an orthogonally angled shape relative to the first plane. A switching actuator is mechanically connected to the first switching conductor and to the second switching conductor adapted to move vertically relative to the first plane, to a first position and to a second position.

Abstract: A method for forming curved image sensors may include applying positive pressure to the face of an image sensor, forcing the image sensor to adhere the curved surface of a substrate. The pressure may be applied to the face of the image sensor in a variety of ways, including using pneumatic pressure, hydraulic pressure, or pressure from an elastic or inelastic solid. Processing may occur on either a single image sensor die or an image sensor wafer. When an image sensor wafer is processed, a substrate may be used that has a number of cavities defined by respective curved surfaces with each cavity corresponding to a respective image sensor. When pressure is applied to the image sensor, the image sensor may deform until the curvature of the image sensor matches the curvature of the curved surface of the underlying substrate.

Abstract: A nozzle deposits a filament of viscous, molten glass onto a print bed, while the print bed rotates about a vertical axis and translates in x, y, and z directions. The deposition is computer controlled, such that the resulting deposited filament forms a desired glass object that is solid after it anneals. One or more motors rotate the print bed such that the direction of deposition of the molten glass is constant relative to the nozzle, even though the print bed is translating in different directions relative to the nozzle. Keeping the direction of deposition constant relative to the nozzle tends to prevent the extruded filament of molten glass from experiencing large, changing, tensile and shear forces that would otherwise occur and that would otherwise damage the filament.

Abstract: In illustrative implementations of this invention, a crucible kiln heats glass such that the glass becomes or remains molten. A nozzle extrudes the molten glass while one or more actuators actuate movements of the nozzle, a build platform or both. A computer controls these movements such that the extruded molten glass is selectively deposited to form a 3D glass object. The selective deposition of molten glass occurs inside an annealing kiln. The annealing kiln anneals the glass after it is extruded. In some cases, the actuators actuate the crucible kiln and nozzle to move in horizontal x, y directions and actuate the build platform to move in a z-direction. In some cases, fluid flows through a cavity or tubes adjacent to the nozzle tip, in order to cool the nozzle tip and thereby reduce the amount of glass that sticks to the nozzle tip.

Abstract: Example implementations relate to a retention assembly. One example retention assembly includes a support member extending from a printed circuit board. The support member includes a body region having a slot and a first flange extending from the body region. The retention assembly also includes a locking member slidably coupled to the support member via the slot. The locking member includes a second flange. The second flange includes a protruded region, and wherein the protruded region and the first flange are to secure a proximal end of expansion module.

Abstract: A nozzle deposits a filament of viscous, molten glass onto a print bed, while the print bed rotates about a vertical axis and translates in x, y, and z directions. The deposition is computer controlled, such that the resulting deposited filament forms a desired glass object that is solid after it anneals. One or more motors rotate the print bed such that the direction of deposition of the molten glass is constant relative to the nozzle, even though the print bed is translating in different directions relative to the nozzle. Keeping the direction of deposition constant relative to the nozzle tends to prevent the extruded filament of molten glass from experiencing large, changing, tensile and shear forces that would otherwise occur and that would otherwise damage the filament.