Abstract: Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes.

Abstract: The present aspects include a system for de-powdering a three-dimensionally (3D) printed structure. The structure comprising a first component holder configured to removably hold the 3D printed structure at an initial orientation with respect to at least one opening to a hollow portion within the 3D printed structure; a fluid system configured control a fluid to at least apply the fluid to the hollow portion or remove the fluid from the hollow portion to remove a powder from the hollow portion; and a movement system configured to move at least the 3D printed structure or the fluid system according to a movement procedure based on a configuration of the hollow portion.

Abstract: A device to control rotation is disclosed. The device includes a stationary portion having an internal aperture with a frustoconical inner surface. The device also includes a movable portion having a frustoconical outer surface, adapted to engage the frustoconical inner surface, to stop rotation between the movable portion and the stationary portion when engaged. An input sleeve is included, configured to transmit an applied rotational force to the device, also configured so that, as the input sleeve moves in a first axial direction, the moveable portion engages the stationary portion, and as the input sleeve moves in a second and opposite axial direction, the moveable portion is pushed out of engagement with the stationary portion.

Abstract: The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.

Abstract: A blood pump assembly can include various components such as a housing and a sensor configured to detect one or more characteristics of the blood. In some embodiments, the sensor can be coupled to the housing and can include a sensor membrane configured to deflect in response to a change in a blood parameter (e.g., pressure). The blood pump assembly can include a shield that covers at least a portion of the sensor membrane so as to protect the sensor from damage when the blood pump assembly is inserted through an introducer and navigated through the patient's vasculature and/or when the blood pump assembly is inserted into the heart in a surgical procedure. One or more protective layers can be deposited over the sensor membrane to prevent the sensor membrane from being dissolved through interactions with the patient's blood.

Abstract: A medical device, comprising a catheter comprising an end-effector, wherein the end-effector further comprises a proximal portion; and a flexible distal portion, wherein the distal portion further includes a window formed therein; and a flexible ultrasonic waveguide disposed within the end-effector, wherein the waveguide includes an active zone that extends through the window; and a mechanism for bending the waveguide, bending the distal portion, or bending both the waveguide and the distal portion, wherein the mechanism permits desired positioning of the waveguide within a lumen.

Abstract: A vehicle includes a holding tank including a plurality of segments, each configured to hold an individual product, a plurality of suspension assemblies supporting the vehicle, and a volume determination system. The volume determination system is configured to receive image data from at least one imager system of the vehicle during a first filling process of a first segment of the holding tank, analyze the received image data to identify a termination of the first filling process, responsive to identifying the termination of the first filling process, receive first pressure measurements from the plurality of suspension assemblies, based at least partially on the received first pressure measurements, determine a volume of a first product within the first segment of the holding tank, and cause the determined volume of the product within the first segment of the plurality of segments to be output to an operator of the vehicle.

Abstract: A vehicle includes a holding tank having a plurality of segments, each segment configured to hold an individual product, a plurality of suspension assemblies supporting the vehicle, and a volume determination system. The volume determination system is configured to receive an indication when a first segment of the plurality of segments of the holding tank is being filled with a first product via a first filling process, responsive to an input that the first filling process of the first segment is complete, receive first pressure measurements from the plurality of suspension assemblies, based at least partially on the received first pressure measurements, determine a volume of the first product within the first segment of the plurality of segments of the holding tank, and cause the determined volume of the first product within the first segment of the plurality of segments to be output to an operator of the vehicle.

Abstract: The present invention provides methods for treating or preventing aggression, agitation, irritability and/or anger in a subject comprising administrating to a subject in need thereof a therapeutically effective amount of a compound of Formula (I).

Abstract: The present invention discloses a conjugate comprising an antigen (for example a saccharide antigen) covalently linked to a Pseudomonas aeruginosa PcrV carrier protein comprising an amino acid sequence which is at least 80% identical to the sequence of SEQ ID NO:1-4, wherein the antigen is linked (either directly or through a linker) to an amino acid residue of the P. aeruginosa PcrV carrier protein. The invention also discloses Pseudomonas aeruginosa PcrV proteins that contain glycosylation site consensus sequences.

Abstract: A driver assistance system in a host vehicle is provided. The driver assistance system is configured to: track a plurality of obstacles in front of the host vehicle; receive host vehicle driver selection of a follow operating mode for the driver assistance system via a human machine interface (HMI); identify a candidate lead vehicle from the plurality of tracked obstacles; provide, via the HMI, a line of sight view in front of the host vehicle that includes the candidate lead vehicle; receive host vehicle driver selection of the candidate lead vehicle as a lead vehicle to follow; adjust a desired trajectory calculated by the driver assistance system to obtain and maintain a desired headway between the lead vehicle and the host vehicle; and generate control signals for vehicle actuators to control the host vehicle to follow the desired trajectory to follow the lead vehicle.

Abstract: A gas turbine engine that defines a radial direction and axial direction. The gas turbine engine includes a compressor section that includes a high pressure compressor. The high pressure compressor includes an aft-most compressor stage. The aft-most compressor stage includes a rotor, a low pressure shaft, a high pressure shaft drivingly coupled to the high pressure compressor. The high pressure shaft includes a central spool member and a forward spool member. The forward spool member extending between the central spool member and the aft-most compressor stage. The aft-most compressor stage further includes an air guide coupled to the aft-most compressor stage and the high pressure shaft. The air guide and a radially inward side of the forward spool member together defines an air flow passage for providing a cooling air flow.

Abstract: Filaments that contain a filament-forming material and an additive, nonwoven webs, and methods for making such filaments are provided.

Abstract: Methods, devices and systems are disclosed for inter-app communications between software applications on a mobile communications device. In one aspect, a computer-readable medium on a mobile computing device comprising an inter-application communication data structure to facilitate transitioning and distributing data between software applications in a shared app group for an operating system of the mobile computing device includes a scheme field of the data structure providing a scheme id associated with a target software app to transition to from a source software app, wherein the scheme id is listed on a scheme list stored with the source software app; and a payload field of the data structure providing data and/or an identification where to access data in a shared file system accessible to the software applications in the shared app group, wherein the payload field is encrypted.

Abstract: An absorbent article can have a topsheet layer, a liquid impermeable layer, and an absorbent core positioned between the topsheet layer and the liquid impermeable layer. The absorbent article can further include an exudate management layer in fluid communication with the topsheet layer. In various embodiments, the exudate management layer can be positioned on a body facing surface of the topsheet layer. In various embodiments, the exudate management layer can be positioned between the topsheet layer and the absorbent core. The exudate management layer has a first component which defines an opening for direct passage of body exudates into the absorbent core. The exudate management layer has a second component which at least partially overlaps the first component of the exudate management layer and further extends in the longitudinal direction of the absorbent article in a direction towards the posterior region of the absorbent article.

Abstract: Glass articles including one or more 3D printed surface features attached to a surface of a substrate at a contact interface between the 3D printed surface feature and the surface. The 3D printed surface feature(s) include a glass or a glass-ceramic, a compressive stress region at an exterior perimeter surface of the 3D printed surface feature(s), and a central tension region interior of the compressive stress region. The 3D printed surface feature(s) may be formed of a contiguous preformed material 3D printed on a surface of a substrate. The compressive stress region of a 3D printed surface feature may be formed using an ion-exchange process.

Abstract: An excess flow valve (EFV) is disclosed that has an efficient and durable construction. The EFV is efficient in terms of both size and cost. It is durable partly due to a design with few parts and also because of optional all metal construction. In some embodiments, an intumescent material is included that expands to close off the valve by pressing the valve plug into sealing engagement with the valve seat and permanently stopping the flow of gas when a pressure differential or flow velocity threshold is exceeded.

Abstract: Various embodiments of the invention are detection systems and methods for detecting call provenance based on call audio. An exemplary embodiment of the detection system can comprise a characterization unit, a labeling unit, and an identification unit. The characterization unit can extract various characteristics of networks through which a call traversed, based on call audio. The labeling unit can be trained on prior call data and can identify one or more codecs used to encode the call, based on the call audio. The identification unit can utilize the characteristics of traversed networks and the identified codecs, and based on this information, the identification unit can provide a provenance fingerprint for the call. Based on the call provenance fingerprint, the detection system can identify, verify, or provide forensic information about a call audio source.