Abstract: A valve body with an integral bypass includes a primary valve body portion defining a primary bore extending through the primary valve body portion from a primary upstream end to a primary downstream end, the primary bore defining an axis, the primary bore including a primary upstream bore extending through the primary upstream end and a primary downstream bore extending through the primary downstream end, the primary valve body portion configured to house a valve member between the primary upstream bore and the primary downstream bore; and the bypass seamlessly integrated with the primary valve body portion, the bypass defining a bypass bore, the bypass bore including a bypass upstream bore and a bypass downstream bore, the bypass including a bypass valve body disposed between the bypass upstream bore and the bypass downstream bore.

Abstract: A system and method which compensates for phase mixer circuit non-linearities within a clock and data recovery (CDR) system during active operation. The CDR system includes compensation circuitry and phase accumulation circuitry. The compensation circuitry generates a first compensation signal based on a first compensation value. The phase accumulation circuitry receives the first compensation signal and a phase accumulator input update signal. The phase accumulation circuitry combines the first compensation signal with the phase accumulator input update signal to compensate for a first non-linearity within phase mixer (PMI) circuitry.

Abstract: Herein is reported a method for determining the binding interaction with a multimeric antigen of an antibody of the human IgG1 subclass that has at least two binding sites specifically binding to the antigen comprising the steps of 1) determining the binding affinity of the antibody for the multimeric antigen, and 2) incubating a mixture comprising the antibody and a polypeptide that is derived from lysine-gingipain of Porphyromonas gingivalis under conditions and for a time sufficient to cleave the antibody into Fabs and Fc-region, and determining the binding affinity of the Fabs of the antibody for the multimeric, whereby the binding affinity of the antibody to the multimeric antigen to be affinity-driven if the binding affinity determined in both steps are comparable and to be avidity-driven if the binding affinity determined in both steps are different.

Abstract: The present invention discloses a process for engineering a host cell comprising the steps of; a) integrating a first polynucleotide cassette including a first selection marker flanked by a first pair of recombination sites; b) removing the first selection marker by the action of a recombinase which recognises the first pair of recombination sites; c) integrating a second polynucleotide cassette including a second selection marker flanked by a second pair of recombination sites; and d) removing the second selection marker by the action of a recombinase which recognises the second pair of recombination sites. Also disclosed is a host cell genome polynucleotide comprising a first recombinantly engineered region and a second recombinantly engineered region, wherein a first single recombination site is adjacent to the first recombinantly engineered region, and a second single recombination site is adjacent to the second recombinantly engineered region.

Abstract: An optical waveguide adapter assembly comprises a solid core optical waveguide extending between a free end and a coupled end and having a solid waveguiding core with an associated first optical mode field size; a hollow core optical waveguide extending between a free end and a coupled end and having a hollow waveguiding core with an associated second optical mode field size; and an optical mode field adapter extending between a first end and a second end and having a waveguiding core configured to change an optical mode field of a waveguided optical signal substantially between the first optical mode field size at the first end of the optical mode field adapter and the second optical mode field size at the second end of the optical mode field adapter, the first end of the optical mode field adapter joined to the coupled end of the solid core optical waveguide to provide optical coupling between the waveguiding core of the solid core optical waveguide and the waveguiding core of the optical mode field adapter

Abstract: A recoil device is provided for a gun having a barrel with a breech. The device includes a breech nut, a brake assembly, a pneumatic spring and a counter-recoil buffer. The breech nut has first and second adjacent sides. The brake assembly includes a brake cylinder that mounts to the breech nut on the first side. The pneumatic spring mounts to the breech nut on the second side. The counter-recoil buffer attaches to the pneumatic spring. The brake cylinder and the pneumatic spring internally push fluids for recoil absorption and return in response to firing the gun.

Abstract: A method includes associating beats with respective initial beat classifications using a trained machine learning model and based on electrocardiogram data. Using an encoder machine learning model, latent space representations of the electrocardiogram data are generated for beats associated with the initial beat classifications. Similar shaped beats are associated with each other based on the latent space representations.

Abstract: In some embodiments, a method for processing an optical fiber includes: drawing an optical fiber through a draw furnace, conveying the optical fiber through a flame reheating device downstream from the draw furnace, wherein the flame reheating device comprises one or more burners each comprising: a body having a top surface and an opposing bottom surface, an opening within the body extending from the top surface through the body to the bottom surface, wherein the optical fiber passes through the opening, and one or more gas outlets within the body; and igniting a flammable gas provided by the one or more gas outlets to form a flame encircling the optical fiber passing through the opening, wherein the flame heats the optical fiber by at least 100 degrees Celsius at a heating rate exceeding 10,000 degrees Celsius/second.

Abstract: Systems and methods for ensuring medical diagnostic test integrity are disclosed. In particular, systems and methods herein can be used to ensure compliance with testing procedures. Some embodiments provide systems and methods for verifying test results. According to some embodiments, test results can be non-human-readable results that can be interpreted by a computing system.

Abstract: Systems and methods of the present disclosure include at least one building component detection sensor device configured to be deployed within (or proximate to) a building comprised of a plurality of building components. The at least one building component detection sensor device is configured to detect data relating to at least one building component of the plurality of building components. In addition, a building component property determination system includes a processor configured to execute instructions stored in memory to determine one or more properties of the at least one building component based at least in part on the data detected by the at least one building component detection sensor device.

Abstract: Systems and methods are provided for a digital beamformed phased array feed. The system may include a radome configured to allow electromagnetic waves to propagate; a multi-band software defined antenna array tile; a power and clock management subsystem configured to manage power and time of operation; a thermal management subsystem configured to dissipate heat generated by the multi-band software defined antenna array tile; and an enclosure assembly. The multi-band software defined antenna array tile may include a plurality of coupled dipole array antenna elements; a plurality of frequency converters; and a plurality of digital beamformers.

Abstract: A system and a method are disclosed for providing recommendations for sets of security operations for improving security of documents created or executed within an online document system. A supplier entity may select sets of security operations to be performed for a request provided to a signing entity. The online document system computes an aggregate measure of security for the selected sets of security operations and compares it to a threshold measure of security. If the aggregate measure is less than the threshold measure, the online document system uses a machine-learned model to identify additional sets of security operations that when added, results in an updated aggregate measure of security greater than the threshold. The additional sets of security operations are presented to the supplier entity for inclusion within a security operation workflow in combination with the selected sets of security operations.

Abstract: Disclosed herein are non-naturally occurring C. autoethanogenum adapted to electrolyzer off-gas feedstock conditions that possess increased growth rates when compared to naturally occurring naturally occurring C. autoethanogenum.

Abstract: Systems and methods for automatically assessing and monitoring information security effectiveness using collected indicia of sensitive content and indicia of security measure information for a plurality of networked organizational assets/systems to provide respective asset/system value at risk ratings. Elements of the system include automated asset discovery, automated hosting provider and location discovery, collection of information harvested from public sources and, optionally non-public sources, analysis of the collected information against public, non-public, and proprietary sources, and/or mathematical models used to infer broader security program conclusions and to rank asset/system values at risk. Estimates of values at risk are used to prioritize allocation of security measures.

Abstract: The present disclosure relates to a filter housing having a bowl and a head. The bowl is configured to house a portion of a filter cartridge. The bowl has an annular groove disposed about a rim of the bowl. The head is configured to mate with the bowl. The head includes an inlet, outlet, and a pair of levers. The inlet is to receive a flow of fluid into the filter housing. The outlet is to release the flow of fluid from the filter housing. The pair of levers are to draw the bowl partially into the head. Each lever has a first arm configured to mate with the annular groove, a second arm having a bearing surface, and a pivot disposed between the first arm and the second arm. A force upon the bearing surface urges the bowl into the head to form a seal.

Abstract: A gas turbine engine having a waste heat recovery system is provided. The gas turbine engine includes a compressor section, a combustion section, a turbine section, and an exhaust section in serial flow order and together defining a core air flowpath, the exhaust section including a primary exhaust flowpath and a waste heat recovery flowpath parallel to the primary exhaust flowpath; and the waste heat recovery system includes a heat source exchanger positioned in thermal communication with a first portion of the waste heat recovery flowpath.

Abstract: Systems and methods are described in which the location of a tap on the body of a handheld device is determined in real time using data streams from an embedded inertial measurement unit (IMU). Taps may be generated by striking the handheld device with an object (e.g., a finger), or by moving the handheld device in a manner that causes it to strike another object. IMU accelerometer, gyroscopic and/or orientation (relative to the magnetic and/or gravitational pull of the earth) measurements are examined for signatures that distinguish a tap at a location on the body of the device compared with signal characteristics produced by taps at other locations. Neural network and/or numerical methods may be used to perform such classifications.

Abstract: A system and method for establishing a gaming session via cloud services with a first device, receiving information at the first device to establish a connection with a second device, and receiving at the first device instructions from the second device via the connection, wherein the instructions control an aspect of the gaming session.

Abstract: A thermally tempered glass element is provided made of glass with two opposite faces that are under compressive stress of at least 40 MPa. The glass has a working point at which the glass has a viscosity of 104 dPa·s of at most 1350° C. The glass has a viscosity versus temperature profile and a coefficient of thermal expansion versus temperature profile of the glass are such that a variable (750° C.-T13)/(CTELiq-CTEsSol) has a value of at most 5*106 K2. The CTELiq is a coefficient of linear thermal expansion of the glass above a glass transition temperature Tg, the CTESol is a coefficient of linear thermal expansion of the glass in a temperature range from 20° C. to 300° C., and the T13 is a temperature at which the glass has a viscosity of 1013 dPa·s.