Abstract: Provided herein are electrically conductive scaffolds of various shapes suitable for promoting and stimulating tissue regeneration, particularly in nerve repair.

Abstract: Materials and methods are provided to direct the formation of new lymphatics and to reconnect the disrupted lymphatic network. These materials and methods enable to improve survival of lymph nodes and lymph node fragments and their integration into a lymphatic network, following lymph node and lymph node fragments transplantation. The treatment or prevention of lymphedema is also addressed. In certain embodiments, a bundle of fibers or fibrils presented in the composition is effective to stimulate and direct the formation of new lymphatic and blood vessels. The bundle of fibers or fibrils presented in the composition is effective to promote survival of the lymph node or lymph node fragments and integration of the lymph node or lymph node fragments into a lymphatic network in the mammalian subject, at the site of transfer or transplantation.

Abstract: A novel medical device and a method for delivery of a scaffold for treatment of secondary lymphedema and ischemia is provided. In some embodiments a catheter medical device and a magnetic guidance method are provided for delivering cell-seeded implants for guided lymphatic regeneration.

Abstract: Embodiments of the present invention relate to a therapeutic device (graft) comprising a collagen membrane having an aligned uniaxial or biaxial structure such that mammalian cells plated on the membrane align mainly along the direction of the collagen fibrils. In a further aspect, a graft comprising a substantially tubular body, wherein the body has an exterior surface, an interior surface, and at least one lumen extending therethrough such that a fluid flow through the lumen can direct mammalian cell migration. In a further aspect, mammalian cells or growth and angiogenic factors can be optionally attached to the exterior and/or interior surface of the substantially tubular body. In various aspects, the graft can be used as a vascular prosthesis, a stent, or a nerve regeneration scaffold. Methods of preparing and implanting same are also provided.

Abstract: Described herein are gene-activated fibrillar compositions and methods, processes, devices for the design, preparation, manufacture and/or formulation of thereof which are capable to encode at least one polypeptide of interest. Methods treating a disease, disorder and/or condition in a subject by increasing the level of at least one polypeptide of interest, by administering to said subject the gene-activated fibrillar composition are also disclosed.

Abstract: Embodiments of the present invention relate generally to the field of tissue repair and regeneration. More specifically embodiments of present disclosure relate to devices or constructs and methods to prepare various devices or constructs useful in directing cellular repair and controlling tissue regeneration to prevent or minimize postsurgical or post traumatic adhesions, excessive scars and/or fibrotic reactions of injured tissues.

Abstract: Materials and methods are provided to direct the formation of new lymphatics and to reconnect the disrupted lymphatic network. These materials and methods enable to improve survival of lymph nodes and lymph node fragments and their integration into a lymphatic network, following lymph node and lymph node fragments transplantation. The treatment or prevention of lymphedema is also addressed. In certain embodiments, a bundle of fibers or fibrils presented in the composition is effective to stimulate and direct the formation of new lymphatic and blood vessels. The bundle of fibers or fibrils presented in the composition is effective to promote survival of the lymph node or lymph node fragments and integration of the lymph node or lymph node fragments into a lymphatic network in the mammalian subject, at the site of transfer or transplantation.

Abstract: A novel medical device and method for delivery of a scaffold for treatment of secondary lymphedema and ischemia is provided. In some embodiments a catheter medical device and magnetic guidance method are provided for delivering cell-seeded implants for guided lymphatic regeneration.

Abstract: Embodiments of the present invention relate to a therapeutic device (graft) comprising a collagen membrane having an aligned uniaxial or biaxial structure such that mammalian cells plated on the membrane align mainly along the direction of the collagen fibrils. In a further aspect, a graft comprising a substantially tubular body, wherein the body has an exterior surface, an interior surface, and at least one lumen extending therethrough such that a fluid flow through the lumen can direct mammalian cell migration. In a further aspect, mammalian cells or growth and angiogenic factors can be optionally attached to the exterior and/or interior surface of the substantially tubular body. In various aspects, the graft can be used as a vascular prosthesis, a stent, or a nerve regeneration scaffold. Methods of preparing and implanting same are also provided.

Abstract: Embodiments of the present invention relate generally to the field of tissue repair and regeneration. More specifically embodiments of present disclosure relate to devices or constructs and methods to prepare various devices or constructs useful in directing cellular repair and controlling tissue regeneration to prevent or minimize postsurgical or post traumatic adhesions, excessive scars and/or fibrotic reactions of injured tissues.

Abstract: The present invention relates to a liquid crystal display panel with improved image contrast comprising an array of pixel regions and a sequence of a recycling backlight structure comprising broadband rear interference polar (RI-Polar) having a transmission axis AB with preset orientation, a spatial intensity modulation structure comprising a broadband front interference polar (FI-Polar) having a transmission axis approximately parallel to the transmission axis AB, a spectral filtering structure, and antireflection means. Each said pixel region spatially encompasses a plurality of subpixel regions. The RI-Polar and FI-Polar are multilayer structures of stacked layers. At least one layer of each structure is optically anisotropic, made by means of Cascade Crystallization Process and characterized by a globally ordered biaxial crystalline structure with an intermolecular spacing of 3.4±0.3 ? in the direction approximately parallel to the transmission axis AB.

Abstract: A liquid crystal display with a backlight is described. The liquid crystal cell comprising a front panel and a rear panel with polarizing means on each panel, and the front polarizing means includes a reflective polarizer and a dichroic polarizer.

Abstract: The backlight system including, an anisotropic fluorescent thin crystal film with the optical parameters matched to the spectral characteristics of a light source, and a liquid crystal display incorporating the backlight system are disclosed. The backlight system comprises at least one light source having an emission spectrum with at least one peak in the wavelength range between 250 and 450 nanometers, and an anisotropic fluorescent thin crystal film (AF TCF) placed on at least one element of the backlight system so that it is on a light path of the light emitted by the light source. The anisotropic fluorescent thin crystal film is formed by rodlike supramolecules composed of disc-shaped molecules of at least one polycyclic organic compound with conjugated ?-system, emitting polarized visible light when irradiated by light from said wavelength range.

Abstract: The compensator design, which comprises at least two layers of birefringent material, one of them is a positive A-plate and another one is a negative A-plate, makes possible a significant improvement in color rendering properties and contrast ratios of liquid crystal displays over a wide range of viewing angle.

Abstract: The present invention relates to a liquid crystal display panel with improved image contrast comprising an array of pixel regions and a sequence of a recycling backlight structure comprising broadband rear interference polar (RI-Polar) having a transmission axis AB with preset orientation, a spatial intensity modulation structure comprising a broadband front interference polar (FI-Polar) having a transmission axis approximately parallel to the transmission axis AB, a spectral filtering structure, and antireflection means. Each said pixel region spatially encompasses a plurality of subpixel regions. The RI-Polar and FI-Polar are multilayer structures of stacked layers. At least one layer of each structure is optically anisotropic, made by means of Cascade Crystallization Process and characterized by a globally ordered biaxial crystalline structure with an intermolecular spacing of 3.4±0.3 ? in the direction approximately parallel to the transmission axis AB.

Abstract: The present invention relates to a liquid crystal display panel with improved image contrast comprising an array of pixel regions and a sequence of a recycling backlight structure comprising broadband rear interference polar (RI-Polar) having a transmission axis AB with preset orientation, a spatial intensity modulation structure comprising a broadband front interference polar (FI-Polar) having a transmission axis approximately parallel to the transmission axis AB, a spectral filtering structure, and antireflection means. Each said pixel region spatially encompasses a plurality of subpixel regions. The RI-Polar and FI-Polar are multilayer structures of stacked layers. At least one layer of each structure is optically anisotropic, made by means of Cascade Crystallization Process and characterized by a globally ordered biaxial crystalline structure with an intermolecular spacing of 3.4±0.3 ? in the direction approximately parallel to the transmission axis AB.

Abstract: A method of fabrication of an electrooptical device comprises depositing a colloid system of anisometric particles onto at least one electrode and/or onto at least one substrate and/or onto at least one layer of an isotropic or anisotropic material to form at least one layer of an electrooptical material, externally aligning the colloid system to form a preferred alignment of the colloid system particles, drying the colloid system, and forming at least one electrode and/or at least one layer of an isotropic or anisotropic material on at least a portion of the layer of the electrooptical material.

Abstract: A liquid crystal display is provided which comprises a front panel comprising a front alignment layer having an alignment direction, a rear panel comprising a rear alignment layer having an alignment direction, and a liquid crystal layer between the front and rear alignment layers. The liquid crystal layer has a rotational twist angle of about 90° and a pre-tilt angle of not more then 2°. The alignment, material and thickness of the liquid crystal layer are such that at the mid-point of the rotational twist, the direction of liquid crystal directors coincide with an off-normal viewing direction of the liquid crystal display.

Abstract: The present invention relates to the field of color filters, in particular, to a non-absorbing polarization color filters and to high-brightness color liquid crystal display panel with improved image contrast employing non-absorbing polarization color filters and light recycling among neighboring subpixels. The disclosed invention represents a non-absorbing polarization color filter comprising the following elements: a rear broadband multilayer lossless polarizer, a front broadband multilayer lossless polarizer, and a color polarization rotator. The rear broadband multilayer lossless polarizer has a predefined-oriented transmission axis AB. Said front broadband multilayer lossless polarizer is located approximately in parallel with the rear broadband multilayer lossless polarizer, and has a transmission axis approximately parallel or approximately orthogonal with respect to transmission axis AB.

Abstract: A multilayer plate is provided comprising an optically transparent substrate, a protective layer, a conducting layer, and at least one anisotropic thin crystal film. The anisotropic thin crystal film is made of a substance containing aromatic rings and possessing a structure with an interplanar spacing of 3.4±0.2 ? along one of optical axes. The thin crystal film is situated between the substrate and the conducting layer and is separated from the conducting layer by the protective layer. The transmission of the multilayer plate for UV radiation does not exceed 1% at any wavelength below 380 nm.