Patents by Inventor Michael Vazquez

Michael Vazquez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210309618
    Abstract: The present invention relates to the discovery of novel N-(substituted)-1H-1,2,4-triazole-3-carboxamide compounds capable of inhibiting DksA activity in a bacteria cell. In certain embodiments, the compounds are capable of killing or weakening bacteria. In another aspect, the invention relates to methods of treating bacterial infection in a subject in need thereof, the method comprising administering to the subject a compound of the invention.
    Type: Application
    Filed: August 22, 2019
    Publication date: October 7, 2021
    Inventors: Michael Fitzpatrick WEMPE, Andres VAZQUEZ-TORRES, Shaodong DAI
  • Publication number: 20210315074
    Abstract: A luminaire adapted to apply an auto-gradient effect across pixels has an interface coupled by a connection to a controller. The controller has electronic circuitry that receives a predetermined start light parameter for a start pixel of a luminaire and receives a predetermined end light parameter for an end pixel of the first luminaire, the predetermined end light parameter greater than the predetermined start light parameter. The controller circuitry then automatically interpolates a gradient effect for a middle light parameter of each of a plurality of middle pixels of the luminaire based on the start and end predetermined light parameters. The controller circuitry then outputs control signals having the start, end and middle light parameters to the start, end and middle light pixels, respectively, through the connection and to the interface.
    Type: Application
    Filed: April 5, 2021
    Publication date: October 7, 2021
    Inventors: Albert DeMayo, Alejandro Vazquez, Lee Ford Parker, Thomas Kong, Michael Wagner
  • Publication number: 20210277880
    Abstract: A pumping system utilizes a linear actuator to move a shaft attached to two pistons within cylinders to pump a working fluid. A housing is designed with coolant passageways and one-way valves such that movement of the shaft also pumps coolant past cooling fins and over a motor. The shaft is formed of several sections joined by couplers which slide within a bore of the housing. The couplers have a non-round shape and the bore has a complimentary non-round cross section such that rotation of the shaft is prevented.
    Type: Application
    Filed: March 9, 2020
    Publication date: September 9, 2021
    Applicant: Schaeffler Technologies AG & Co. KG
    Inventors: Andre Vazquez, Craig Hooker, Michael White, Michael Conlin, Eric Ovendorf
  • Publication number: 20140068432
    Abstract: The present application is directed towards systems and methods for providing audience interaction with a broadcast media program. A producer, utilizing an intuitive interface provided by a computing device can request audience input by providing polls or questions, which may be transmitted to a plurality of remote computing devices of the audience. An audience member may record a brief audio or video file, of up to a predetermined length, in response to a question via an application executed by their remote computing device. The application may transmit the recorded file to the computing device of the producer, who may review the recorded file and delete it, post it to a website, or download it for playback on air. Accordingly, the resulting system provides the ease, efficiency, and safety of asynchronous communication systems, while allowing audience members to hear their own comments and own voices on air.
    Type: Application
    Filed: August 30, 2012
    Publication date: March 6, 2014
    Inventors: Ezra Kucharz, Adam Wiener, Christopher Oliviero, Adam Bloom, Serafin Michael Vazquez, JR., Allan Bressler, Andrew Dirnberger
  • Publication number: 20080118969
    Abstract: Selected bis-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, compositions, and methods for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.
    Type: Application
    Filed: January 29, 2008
    Publication date: May 22, 2008
    Applicant: G.D. Searle LLC
    Inventors: Daniel Getman, Gary DeCrescenzo, John Freskos, Michael Vazquez, James Sikorski, Balekudru Devadas, Srinivasan Nagarajan, David Brown, Joseph McDonald
  • Publication number: 20080103311
    Abstract: N-heterocyclic moiety containing hydroxyethylamino compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Application
    Filed: December 11, 2007
    Publication date: May 1, 2008
    Applicant: Pharmacia Corporation
    Inventors: John Tally, Daniel Getman, Gary DeCrescenzo, Kathryn Reed, Ko-Chung Lin, John Freskos, Michael Clare, Donald Rogier, Robert Heintz, Michael Vazquez, Richard Mueller
  • Publication number: 20070078146
    Abstract: A class of pyrazole derivatives is described for use in treating p38 kinase medicated disorders. Compounds of particular interest are defined by Formula IA wherein R1, R2, R3 and R4 are as described in the specification.
    Type: Application
    Filed: May 5, 2004
    Publication date: April 5, 2007
    Inventors: Ashok Naraian, Michael Clare, Paul Collins, Joyce Crich, Rajesh Devraj, Daniel Flynn, Lifeng Geng, Matthew Graneto, Cathleen Hanau, Gunnar Hanson, Susan Hartmann, Michael Hepperle, He Huang, Ish Khanna, Francis Koszyk, Shuyuan Liao, Suzanne Metz, Win Naing, Richard Partis, Thao Perry, Shashidhar Rao, Shaun Selness, Michael South, Michael Stealey, John Talley, Michael Vazquez, John Walker, Richard Weier, Xiangdong Xu, Syaulan Yang, Yi Yu
  • Publication number: 20070078173
    Abstract: ?- and ?-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Application
    Filed: September 25, 2006
    Publication date: April 5, 2007
    Applicant: G.D. Searle & Co.
    Inventors: Michael Vazquez, Richard Mueller, John Talley, Daniel Getman, Gary DeCrescenzo, John Freskos, Robert Heintz, Deborah Bertenshaw
  • Publication number: 20070037754
    Abstract: Selected bis-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, compositions, and methods for inhibiting retroviral proteases, such as human inmmunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.
    Type: Application
    Filed: August 10, 2006
    Publication date: February 15, 2007
    Applicant: G.D. Searle & Co.
    Inventors: Daniel Getman, Gary DeCrescenzo, John Freskos, Michael Vazquez, James Sikorski, Balekudru Devadas, Srinivasan Nagarajan, David Brown, Joseph McDonald
  • Publication number: 20070004646
    Abstract: Selected heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, compositions, and methods for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.
    Type: Application
    Filed: June 12, 2006
    Publication date: January 4, 2007
    Applicant: G.D. Searle & Co.
    Inventors: Daniel Getman, Gary DeCrescenzo, John Freskos, Michael Vazquez, James Sikorski, Balekudru Devadas, Srinivasan Nagarajan, David Brown, Joseph McDonald
  • Publication number: 20060264483
    Abstract: Selected sulfonylalkanoylamino hydroxyethylamine sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.
    Type: Application
    Filed: April 4, 2006
    Publication date: November 23, 2006
    Applicant: G.D. Searle & Co.
    Inventors: Daniel Getman, Gary DeCrescenzo, John Freskos, Michael Vazquez, James Sikorski, Balekudru Devadas, Srinivasan Nagarajan, Joseph McDonald
  • Publication number: 20060189611
    Abstract: Selected amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.
    Type: Application
    Filed: January 24, 2006
    Publication date: August 24, 2006
    Applicant: G.D. Searle & Co.
    Inventors: Daniel Getman, Gary DeCrescenzo, John Freskos, Michael Vazquez, James Sikorski, Balekudru Devadas, Srinivasan Nagarajan, David Brown, Joseph McDonald
  • Publication number: 20060166895
    Abstract: N-heterocyclic moiety containing hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Application
    Filed: January 13, 2006
    Publication date: July 27, 2006
    Applicant: Monsanto Company (now named Pharmacia Corporation, which is a wholly owned subsidiary of Pfizer, Inc
    Inventors: John Talley, Daniel Getman, Gary DeCrescenzo, Kathryn Reed, Ko-Chung Lin, John Freskos, Michael Clare, Donald Rogier, Robert Heintz, Michael Vazquez, Richard Mueller
  • Publication number: 20060094789
    Abstract: ?- and ?-amino acid hydroxyethylamino sulfonyl urea derivative compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Application
    Filed: September 27, 2005
    Publication date: May 4, 2006
    Applicant: G.D. Searle & Co.
    Inventors: Michael Vazquez, Richard Mueller, John Talley, Daniel Getman, Gary DeCrescenzo, Eric Sun
  • Publication number: 20060020009
    Abstract: Succinoylamino hydroxyethylamino sulfonyl urea derivatives of the formula: wherein R1-R6, R7, R7?, R8, R30-R34, X?, Y, Y?, t, x, and n are as defined herein, are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Application
    Filed: July 18, 2005
    Publication date: January 26, 2006
    Applicant: G.D. Searle & Co.
    Inventors: Michael Vazquez, Richard Mueller, John Talley, Daniel Getman, Gary DeCrescenzo, Eric Sun
  • Publication number: 20050267171
    Abstract: ?- and ?-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
    Type: Application
    Filed: April 21, 2005
    Publication date: December 1, 2005
    Applicant: G.D. Searle & Co.
    Inventors: Michael Vazquez, Richard Mueller, John Talley, Daniel Getman, Gary DeCrescenzo, John Freskos, Deborah Bertenshaw, Robert Heintz
  • Publication number: 20050267214
    Abstract: Certain Alpha- and Beta-amino acid hydroxyethylamino sulfamic acid derivatives represented by the following formula are useful as retroviral protease inhibitors:
    Type: Application
    Filed: June 28, 2005
    Publication date: December 1, 2005
    Applicant: G.D. Searle & Co.
    Inventors: Michael Vazquez, Richard Mueller, John Talley, Daniel Getman, Gary DeCrescenzo, Eric Sun
  • Publication number: 20050256180
    Abstract: The present invention relates to substituted pyrazolyl derivatives, compositions comprising such, intermediates, methods of making substituted pyrazolyl derivatives, and methods for treating cancer, inflammation, and inflammation-associated disorders, such as arthritis.
    Type: Application
    Filed: April 25, 2005
    Publication date: November 17, 2005
    Inventors: Arija Bergmanis, Michael Clare, Joyce Crich, Lifeng Geng, Timothy Hagen, Gunnar Hanson, Stephen Houdek, He Huang, Donna Iula, Francis Koszyk, Shuyuan Liao, Scott Mohler, Maria Nguyen, Richard Partis, Michael Stealey, Michael Tollefson, Richard Weier, Xiangdong Xu, Dominique Bonafoux, Theresa Fletcher, Bruce Hamper, Patrick Lennon, Subo Liao, Suzanne Metz, David Oburn, Thomas Owen, Angela Scates, Michael Vazquez, Serge Wolfson
  • Patent number: D804599
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: December 5, 2017
    Assignee: Lights Out Productions, LLC
    Inventors: Michael Vazquez, Jose Manuel Suris
  • Patent number: D805596
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: December 19, 2017
    Assignee: Lights Out Productions, LLC
    Inventors: Michael Vazquez, Jose Manuel Suris