Abstract: A process for identifying and treating cells in a living organism. The cells are labeled, circulated within the organism, detected with an implanted detector, and then either isolated or ablated.

Abstract: An apparatus for treating a biological organism comprising a device for emitting and delivering energy to the biological organism, a programmable controller for varying the type and amount of energy emitted, and apparatus for sensing a condition of the biological organism.

Abstract: A cardiac assist device senses conditions of a heart and controls the generation of various electrical stimuli in response to sense conditions of the heart. The cardiac assist device generates a electrical pulse so as to defibrillate a fibrillated heart when the cardiac assist device determines from the sensed conditions a state of fibrillation. The cardiac assist device generates a chaos control electrical signal so as to bring a pre-fibrillated heart condition back into a normal beating condition when the cardiac assist device determines from the sensed conditions a pre-state of fibrillation. Lastly, the cardiac assist device generates an electrical enhancement signal that causes a threshold of pacing cells in the heart to be exceeded in response to a subthreshold stimulus when the cardiac assist device determines from the sensed conditions a subthreshold pacing signal.

Abstract: A coherent radiation imaging system that produces digital images with a reduced amount of speckle. Radiation from a long coherence length source is used to form an image of a sample. The output coherent wave is temporally divided into a plurality of wavelets. The spatial phase of each wavelet is then modulated a known and different amount. Each phase modulated wavelet illuminates the sample and is perturbed by its interaction with the sample. A spatial phase map of each perturbed wavelet is then created and converted to a sample image with an image reconstruction program. The plurality of sample images thus formed is statistically averaged to form a final averaged image. The high frequency speckle that is not optically resolvable tends to average to zero with continual statistical averaging, leaving only the optically resolvable lower frequency phase information.

Abstract: An apparatus and method for performing rapid DNA sequencing, such as genomic sequencing, is provided herein. The method includes the steps of preparing a sample DNA for genomic sequencing, amplifying the prepared DNA in a representative manner, and performing multiple sequencing reaction on the amplified DNA with only one primer hybridization step.

Abstract: An electromagnetic shield has a first patterned or apertured layer having non-conductive materials and conductive material and a second patterned or apertured layer having non-conductive materials and conductive material. The conductive material may be a metal, a carbon composite, or a polymer composite. The non-conductive materials in the first patterned or apertured layer may be randomly located or located in a predetermined segmented pattern such that the non-conductive materials in the first patterned or apertured layer are located in a predetermined segmented pattern with respect to locations of the non-conductive materials in the second patterned or apertured layer.

Abstract: An electromagnetic shield has a first patterned or apertured layer having non-conductive materials and conductive material and a second patterned or apertured layer having non-conductive materials and conductive material. The conductive material may be a metal, a carbon composite, or a polymer composite. The non-conductive materials in the first patterned or apertured layer may be randomly located or located in a predetermined segmented pattern such that the non-conductive materials in the first patterned or apertured layer are located in a predetermined segmented pattern with respect to locations of the non-conductive materials in the second patterned or apertured layer.

Abstract: An electromagnetic shield has a first patterned or apertured layer having non-conductive materials and conductive material and a second patterned or apertured layer having non-conductive materials and conductive material. The conductive material may be a metal, a carbon composite, or a polymer composite. The non-conductive materials in the first patterned or apertured layer may be randomly located or located in a predetermined segmented pattern such that the non-conductive materials in the first patterned or apertured layer are located in a predetermined segmented pattern with respect to locations of the non-conductive materials in the second patterned or apertured layer.

Abstract: An electromagnetic shield has a first patterned or apertured layer having non-conductive materials and conductive material and a second patterned or apertured layer having non-conductive materials and conductive material. The conductive material may be a metal, a carbon composite, or a polymer composite. The non-conductive materials in the first patterned or apertured layer may be randomly located or located in a predetermined segmented pattern such that the non-conductive materials in the first patterned or apertured layer are located in a predetermined segmented pattern with respect to locations of the non-conductive materials in the second patterned or apertured layer.

Abstract: An electromagnetic shield has a first patterned or apertured layer having non-conductive materials and conductive material and a second patterned or apertured layer having non-conductive materials and conductive material. The conductive material may be a metal, a carbon composite, or a polymer composite. The non-conductive materials in the first patterned or apertured layer may be randomly located or located in a predetermined segmented pattern such that the non-conductive materials in the first patterned or apertured layer are located in a predetermined segmented pattern with respect to locations of the non-conductive materials in the second patterned or apertured layer.

Abstract: Disclosed is an artificial organ comprised of a conduit adapted to be connected to a blood pool, the blood pool comprising a first analyte and a second analyte; a cell culture media comprised of a first cell culture and a second cell culture, each of which are capable of producing the first analyte and said second analyte respectively; and a controller that is capable of measuring a concentration of the first and second analyte in the blood pool, and delivering a specified amount of the first and second analyte from the cell culture media to the blood pool, and delivering a specified amount of the second analyte from the cell culture media to the blood pool.

Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.

Abstract: A medical device containing a device for connecting the medical device to a substrate, for furnishing electrical impulses from the medical device to the substrate, for ceasing the furnishing of electrical impulses to the substrate, for receiving pulsed radio frequency fields, for transmitting and receiving optical signals, and for protecting the substrate and the medical device from currents induced by the pulsed radio frequency fields. The medical device contains a control circuit comprised of a parallel resonant frequency circuit.

Abstract: A Voice-driven control device for a media system includes a housing; a controller; a first communication port to enable communication of instructions between a data processing system and the controller; and a second communication port to enable communication of instructions between a media device and the controller. The controller includes a voice recognition system to recognize human speech and to convert the human speech into a first set of commands and into a second set of commands. The first set of commands provides instructions to the data-processing system to enable voice driven control of a media presentation. The second set of commands provides instructions to the media device to enable voice driven control of a functionality of the media device.

Abstract: The present invention relates to the field of fluid dynamics. More specifically, this invention relates to methods and apparatus for conducting densely packed, independent chemical reactions in parallel in a substantially two-dimensional array. Accordingly, this invention also focuses on the use of this array for applications such as DNA sequencing, most preferably pyrosequencing, and DNA amplification.

Abstract: An implantable device used to monitor and maintain at least one physiologic function, which is capable of operating in the presence of damaging electromagnetic interference. The implantable device includes primary and secondary modules, each independently protected from EMI damage via at least one shielding and/or filtering, and a non-electrical communication device for communicating in at least one direction between the primary and the secondary modules. The primary module, in response to input from electrical sensing leads, activates the secondary module in a failsafe mode. In the failsafe mode, the secondary module carries out a physiologic function upon activation and in the presence of electromagnetic interference.

Abstract: An apparatus and method for interactive transmission and reception of tactile information, comprising means for creating a signal representative of a human tactile event, means for transmitting the signal to a remote recipient, and, means for decoding the signal in a manner which conveys tactile information to a recipient.

Abstract: The present invention relates to the field of fluid dynamics. More specifically, this invention relates to methods and apparatus for conducting densely packed, independent chemical reactions in parallel in a substantially two-dimensional array. Accordingly, this invention also focuses on the use of this array for applications such as DNA sequencing, most preferably pyrosequencing, and DNA amplification.

Abstract: A process for determining the status of a living organism. In this process, cellular material which contains a first microtubule, a second microtuble, and a multiplicity of microtubule associated proteins is imaged to determine both the positions of the microtubles and the positions of the microtubule associated proteins located between the microtubules. The pattern of microtubules associated protein attachment is therein correlated with historic phenotypic data to determine whether there is any abnormality in the sample specimen.

Abstract: A controllable, wearable MRI-compatible, fixed-rate (VOO) pacemaker includes a self-contained power source and a pulse generator housed at the proximal end of a photonic catheter in a first enclosure designed to operate externally of a patient's body. Electrical pulses output by the pulse generator are converted into light energy and directed into the proximal end of the photonic catheter. The photonic catheter includes an optical conduction pathway over which is formed a covering of biocompatible material. Light entering the proximal end of the photonic catheter is transmitted through the optical conduction pathway, where it is collected and converted back to electrical energy at a second enclosure located at the distal end of the photonic catheter. The second enclosure houses an opto-electrical transducer that converts the optical pulses to electrical pulses and delivers them to bipolar heart electrodes.