Patents by Inventor Michael Wolfe

Michael Wolfe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10538586
    Abstract: The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: January 21, 2020
    Assignee: MHS CARE-INNOVATION LLC
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Publication number: 20190322738
    Abstract: The present disclosure is directed to the treatment of ischemic heart disease and clinical conditions associated with ischemic heart disease. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in cardioprotective effects against acute myocardial infarction, such as a decrease in circulating triglycerides, total cholesterol, and low-density lipoproteins, and an increase in the ratio of high-density lipoprotein to total cholesterol.
    Type: Application
    Filed: July 10, 2019
    Publication date: October 24, 2019
    Inventor: M. Michael Wolfe
  • Patent number: 10196441
    Abstract: The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: February 5, 2019
    Assignee: THE METROHEALTH SYSTEM
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Publication number: 20190020392
    Abstract: Systems and methods for operating an antenna providing a coverage area using beamforming and carrier aggregation techniques. The proposed system aims to optimize the use of carrier aggregation for beamforming systems. The system may include a beamforming module coupled to first array and second arrays of radiating elements, the first array being configured to provide wireless coverage on a first frequency carrier in a first coverage area, and the second array being configured to provide wireless coverage on a second frequency carrier in a second coverage area. The beamforming module may be configured to receive one or more indicators associated with one or more user equipments (UEs) in the coverage area. Based on the one or more indicators, the beam-forming module may be configured to dynamically adjust, in the RF domain, at least one of a location of the second coverage area and a size of the second coverage area.
    Type: Application
    Filed: January 5, 2017
    Publication date: January 17, 2019
    Inventors: Ray BUTLER, Scott MICHAELIS, Pedro TORRES MARTOS, Louis MEYER, Martin ZIMMERMAN, Sammit PATEL, Mohamed Nadder HAMDY, Morgan KURK, Michael WOLFE
  • Publication number: 20180140630
    Abstract: A combination of an antacid, alginate, and a histamine H2-receptor antagonist, and methods of using the same for providing fast and lasting relief of symptoms of episodic heartburn are provided.
    Type: Application
    Filed: November 22, 2017
    Publication date: May 24, 2018
    Inventors: M. Michael Wolfe, Steven B. Landau, Abhijeet Waghray, Nisheet Waghray
  • Publication number: 20180030133
    Abstract: The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
    Type: Application
    Filed: September 25, 2017
    Publication date: February 1, 2018
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Publication number: 20180028618
    Abstract: The present disclosure is directed to the treatment of diseases or conditions characterized by the buildup of fatty tissue, or hyperphagia, such as Prader-Willi syndrome, obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain, weight loss, and/or reduction in fatty tissue, and a marked decrease in lipid synthesis and accumulation.
    Type: Application
    Filed: September 25, 2017
    Publication date: February 1, 2018
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Patent number: 9771422
    Abstract: The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: September 26, 2017
    Assignee: MHS CARE-INNOVATION LLC
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Publication number: 20170044254
    Abstract: The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
    Type: Application
    Filed: October 26, 2016
    Publication date: February 16, 2017
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Patent number: 9280076
    Abstract: A toner includes a core including a homogenized mixture of a first polyester latex, a styrene/acrylate latex, and a compatibilizing agent latex that includes a graft polyester-styrene/acrylate copolymer and a shell that includes a polyester latex. A process includes (1) homogenizing a mixture to form a plurality of core particles, the mixture including a first polyester latex, a styrene/acrylate latex, and a compatibilizing agent latex comprising a graft polyester-styrene/acrylate copolymer and (2) adding a shell polyester latex to the plurality of core particles to form a plurality of core-shell structures.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: March 8, 2016
    Assignee: XEROX CORPORATION
    Inventors: Shigeng Li, Christopher Michael Wolfe, Yanjia Zuo, Randy Pheav Tin, John L. Pawlak, Jay Lee Schneider, Peter Nguyen, Jordan Frank, Chieh-Min Cheng
  • Patent number: 9122179
    Abstract: A method of forming toner particles includes aggregating a mixture of a latex, a wax, and an optional pigment to form pre-toner particles, and coalescing the pre-toner particles at a substantially constant target temperature selected within a range from about the glass transition temperature of the pre-toner particles to about 75° C., thereby creating toner particles having a substantially constant particle size distribution during the coalescing step.
    Type: Grant
    Filed: August 21, 2013
    Date of Patent: September 1, 2015
    Assignee: XEROX CORPORATION
    Inventors: Jay Lee Schneider, Abdisamed Sheik-Qasim, Randy Pheav Tin, Christopher Michael Wolfe, Richard Philip Nelson Veregin, Mark Elliott, Melanie Davis, Cuong Vong, Shigang Steven Qiu
  • Publication number: 20150166657
    Abstract: The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
    Type: Application
    Filed: December 17, 2014
    Publication date: June 18, 2015
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Publication number: 20150056551
    Abstract: A method of forming toner particles includes aggregating a mixture of a latex, a wax, and an optional pigment to form pre-toner particles, and coalescing the pre-toner particles at a substantially constant target temperature selected within a range from about the glass transition temperature of the pre-toner particles to about 75° C., thereby creating toner particles having a substantially constant particle size distribution during the coalescing step.
    Type: Application
    Filed: August 21, 2013
    Publication date: February 26, 2015
    Applicant: XEROX CORPORATION
    Inventors: Jay Lee Schneider, Abdisamed Sheik-Qasim, Randy Pheav Tin, Christopher Michael Wolfe, Richard Philip Nelson Veregin, Mark Elliott, Melanie Davis, Cuong Vong, Shigang Steven Qiu
  • Patent number: 7908264
    Abstract: Queries to an enterprise data system based on discrete groups of servers may display the sets of data satisfying a query as if the query results originated from a single data repository. Further, queries within the system may efficiently search through a large set of satisfying records while accounting for data latency or system performance.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: March 15, 2011
    Assignee: Mypoints.com Inc.
    Inventors: James John Bohannon, Greg Michael Wolfe
  • Patent number: 7777480
    Abstract: An antenna orientation sensor, having a base, a pivoting support coupled to the base. An actuator operable to move the pivoting support through a calibration movement with respect to the base. A magnetic sensor on the pivoting support and a position sensor operable to sense the position of the pivoting support within the calibration movement.
    Type: Grant
    Filed: September 8, 2007
    Date of Patent: August 17, 2010
    Inventor: Michael Wolfe
  • Publication number: 20090291883
    Abstract: The present invention provides methods and compositions for the treatment and prevention of neoplasia by administering an effective amount of a NSAID in combination with an effective amount of an immunosuppressant agent. In particular, the present invention provides methods and compositions for the treatment and prevention of neoplasia by administering an effective amount of COX-2 inhibitor in combination with an effective amount of an immunosuppressant agent.
    Type: Application
    Filed: July 16, 2007
    Publication date: November 26, 2009
    Applicant: BOSTON MEDICAL CENTER CORPORATION
    Inventors: M. Michael Wolfe, Min Yao
  • Publication number: 20090066323
    Abstract: An antenna orientation sensor, having a base, a pivoting support coupled to the base. An actuator operable to move the pivoting support through a calibration movement with respect to the base. A, for example, three axis magnetic sensor on the pivoting support and a position sensor operable to sense the position of the pivoting support within the calibration movement.
    Type: Application
    Filed: September 8, 2007
    Publication date: March 12, 2009
    Applicant: ANDREW CORPORATION
    Inventor: Michael Wolfe
  • Publication number: 20080214619
    Abstract: Pharmaceutical proton pump inhibitor (PPI) medications and methods are disclosed for preventing and/or treating gastrointestinal disorders characterized by abnormalities in gastric acid secretion at anytime of the day or night without the need for food effect or to be taken with food. The medications comprise a PPI and a cholinergic agonist for inducing rapid onset of PPI action, for increasing the duration of PPI efficacy and for optimizing clinical PPI effectiveness that may be administered at any time of the day or night without food or on an empty stomach, and possibly on an as-needed or on demand basis. In carrying out the methods, a PPI and cholinergic agonist may be administered together as a single unitary dose in the form of a liquid or solid, or administered together, but separately as either liquids or solids or a combination thereof. Preferably, an oral solid dosage form of the present invention allows for release of a proton pump inhibitor at a pH of about 5 or higher, e.g., pH about 5.5, 6, 6.
    Type: Application
    Filed: July 30, 2007
    Publication date: September 4, 2008
    Inventors: M. Michael Wolfe, Larry R. Brown, Peter J. Manso
  • Publication number: 20080182795
    Abstract: In one embodiment, this invention provides an antagonist of glucose-dependent insulinotropic polypeptide (GIP) consisting essentially of a 24 amino acid polypeptide corresponding to positions 7-30 of the sequence of GIP. In another embodiment, this invention provides a method of treating non-insulin dependent diabetes mellitus in a patient comprising administering to the patient an antagonist of glucose-dependent insulinotropic polypeptide (GIP). In yet another embodiment, this invention provides a method of improving glucose tolerance in a mammal comprising administering to the mammal an antagonist of glucose-dependent insulinotropic polypeptide (GIP).
    Type: Application
    Filed: March 4, 2008
    Publication date: July 31, 2008
    Applicant: Boston Medical Center
    Inventors: M. Michael Wolfe, Chi-Chuan Tseng, Linda Neville
  • Publication number: 20080125371
    Abstract: In one embodiment, this invention provides an antagonist of glucose-dependent insulinotropic polypeptide (GIP) consisting essentially of a 24 amino acid polypeptide corresponding to positions 7-30 of the sequence of GIP. In another embodiment, this invention provides a method of preventing and treating obesity and non-insulin dependent diabetes mellitus (Type II) in a patient comprising administering to the patient an antagonist of glucose-dependent insulinotropic polypeptide (GIP). In yet another embodiment, this invention provides a method of improving glucose tolerance in a mammal comprising administering to the mammal an antagonist of glucose-dependent insulinotropic polypeptide (GIP).
    Type: Application
    Filed: August 15, 2006
    Publication date: May 29, 2008
    Inventors: M. Michael Wolfe, Chi-Chuan Tseng, Linda Neville