Patents by Inventor Michael Wong
Michael Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12215327Abstract: The present disclosure provides genetically modified host cells that produce a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative. The present disclosure provides methods of synthesizing a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative.Type: GrantFiled: November 14, 2022Date of Patent: February 4, 2025Assignee: The Regents of the University of CaliforniaInventors: Jay D. Keasling, Leo D'Espaux, Jeff Wong, Xiaozhou Luo, Michael Reiter, Charles Denby, Anna Lechner
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Publication number: 20250037120Abstract: Various aspects of the subject technology relate to systems, methods, and machine-readable media for cross-chain communication in a blockchain platform. Various aspects may include accepting, at a first blockchain, a first transaction including a message and a message payload. Aspects may also include validating, at the first blockchain, the message by signing the message using signature keys of one or more validators in a first set of validators of the first blockchain. Aspects may also include generating an aggregate signature based on the signature keys of the one or more validators in a first set of validators. Aspects may also include submitting a second transaction on to a second blockchain, the second transaction including the message and the aggregate signature. Aspects may include validating, at the second blockchain, the second transaction based on a shared registry.Type: ApplicationFiled: October 8, 2024Publication date: January 30, 2025Inventors: Michael Edmond Kaplan, Stephen Buttolph, Daniel Laine, Alexander Dunn, Cameron John Schultz, Aaron Buchwald, Patrick Robert O'Grady, Bernard Wong
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Patent number: 12210360Abstract: A method includes receiving sensor data collected by an autonomous mobile robot as the autonomous mobile robot moves about an environment, the sensor data being indicative of sensor events and locations associated with the sensor events. The method includes identifying a subset of the sensor events based on the locations. The method includes providing, to a user computing device, data indicative of a recommended behavior control zone in the environment, the recommended behavior control zone containing a subset of the locations associated with the subset of the sensor events. The method includes defining, in response to a user selection from the user computing device, a behavior control zone such that the autonomous mobile robot initiates a behavior in response to encountering the behavior control zone, the behavior control zone being based on the recommended behavior control zone.Type: GrantFiled: September 23, 2022Date of Patent: January 28, 2025Assignee: iRobot CorporationInventors: Shipra Arora, Michael Foster, Frank Judge, Brandon Rohrer, Christopher Shumaker, Matthew Weyant, Alex Wong, Lauren D. Stern
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Patent number: 12210040Abstract: Systems and methods described herein are directed towards integrating a shield layer into a current sensor to shield a magnetic field sensing element and associated circuitry in the current sensor from electrical, voltage, or electrical transient noise. In an embodiment, a shield layer may be disposed along at least one surface of a die supporting a magnetic field sensing element. The shield layer may be disposed in various arrangements to shunt noise caused by a parasitic coupling between the magnetic field sensing element and the current carrying conductor away from the magnetic field sensing element.Type: GrantFiled: January 19, 2022Date of Patent: January 28, 2025Assignee: Allegro MicroSystems, LLCInventors: Shaun D. Milano, Bryan Cadugan, Michael C. Doogue, Alexander Latham, William P. Taylor, Harianto Wong, Sundar Chetlur
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Publication number: 20250025629Abstract: A treatment delivery system includes a fluid delivery system connected to a first fluid reservoir and a second fluid reservoir. The system directs a first fluid from the first fluid reservoir to a treatment site and directs a second fluid from the second fluid reservoir to the treatment site and a control unit to control the fluid delivery system according to a treatment process comprising a flow of the first fluid and the second fluid, the treatment process including multiple phases. A first phase includes a controlled delivery of the first fluid from the first fluid reservoir to the treatment site. A second phase of the plurality of phases includes a controlled delivery of the second fluid from the second fluid reservoir to the treatment site, the control unit automatically activating a transition from at least the first phase to the second phase.Type: ApplicationFiled: October 8, 2024Publication date: January 23, 2025Inventors: Robert C. Hutton, Brian C. de Beaubien, Matthew Gill, Douglas Lorang, James McCrea, Jude Paganelli, Andrew Sauter, Michael Wong
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Publication number: 20250026801Abstract: Provided herein are methods of treating a subject by administering a combination of an activatable cytokine construct (ACC) and a PD-1/PD-L1 pathway inhibitor in which the ACC includes: a first monomer construct including an optional first peptide mask (PM1), an optional third cleavable moiety (CM3), a first mature cytokine protein (CP1), a first cleavable moiety (CM1), and a first dimerization domain (DD1), wherein the CM1 is positioned between the CP1 and the DD1; and a second monomer construct including an optional second peptide mask (PM2), an optional forth cleavable moiety (CM4), a second mature cytokine protein (CP2), a second cleavable moiety (CM2), and a second dimerization domain (DD2), wherein the CM2 is positioned between the CP2 and the DD2; wherein the DD1 and the DD2 bind to each other thereby forming a dimer of the first monomer construct and the second monomer construct; and where the ACC is characterized by a reduction in at least one activity of the CP1 and/or CP2 as compared to a control lType: ApplicationFiled: January 25, 2024Publication date: January 23, 2025Applicant: CytomX Therapeutics, Inc.Inventors: Alexey Yevgenyevich Berezhnoy, Nicole G. Lapuyade, Na Cai, Michael B. Winter, Kenneth Wong, Madan M. Paidhungat, Dylan L. Daniel, Erwan Le Scolan
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Publication number: 20250018940Abstract: Vehicles and related systems and methods are provided for mitigating lane departures, alternatively referred to as lane keeping assistance. One method of assisting vehicle operation involves determining a control trajectory for the vehicle over a prediction horizon that satisfies one or more steering angle constraints for operating a steering system of the vehicle based at least in part on a current steering angle, a first difference between the control trajectory and a reference lateral trajectory for the vehicle and a second difference between the control trajectory and a lane boundary, for example, by minimizing a weighted sum of the differences. The method continues by determining a steering angle command for the vehicle based at least in part on the control trajectory and autonomously operating one or more actuators onboard the vehicle in accordance with the steering angle command prior to the vehicle crossing the lane boundary.Type: ApplicationFiled: July 14, 2023Publication date: January 16, 2025Applicant: GM GLOBAL TECHNOLOGY OPERATIONS LLCInventors: Reza Zarringhalam, Jimmy Lu, Jackson Barry McGrory, Mohammed Raju Hossain, Kin Man Michael Wong, Amirreza Mirbeygi Moghaddam
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Publication number: 20240427753Abstract: A performance measurement indexing system indexes a data store containing data entries indicative of message processing by an application. The application includes a plurality of checkpoints, and the data store contains data logged upon each message traversing the checkpoints in the application. The performance measurement indexing system determines which data entries relate to messages that satisfy a delay condition, and limits queries run on the data store to those data entries, thereby increasing the speed and efficiency with which queries can be serviced.Type: ApplicationFiled: September 6, 2024Publication date: December 26, 2024Applicant: Chicago Mercantile Exchange Inc.Inventors: Kyle Dennis Kavanagh, José Antonio Acuña-Rohter, David Michael Wong
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Publication number: 20240408342Abstract: A respiratory mask system includes a mask interface and a headgear assembly. The headgear assembly is adjustable and comprised of an elastic portion, a non-elastic portion and a restriction mechanism configured to provide a force resisting movement of the non-elastic portion when the elastic portion is extended. There is a support beam coupled to the non-elastic portion and extending along a portion of the headgear that is curved along its longitudinal extent. In this way particular seal modules can be comfortably fitted to a user and any blow off force is mitigated. A particular example of the respiratory mask system includes provision for removable attachment between the seal and a mask frame, the mask frame and a yoke of the headgear; and between a conduit and the mask frame.Type: ApplicationFiled: June 21, 2024Publication date: December 12, 2024Inventors: Christopher Gareth SIMS, Fadi Karim Moh'd MASHAL, Vitaly KAPELEVICH, Mark Arvind MCLAREN, Silas Sao Jin SIEW, Jonathan Mark DOWNEY, Christopher Michael WONG, Matthew Aaron BRADLEY, Janine Elizabeth COLLINS, Dillan PATEL, Steve THOMAS, Chris Onin Limpin HIPOLITO, Priyanka Ferdinand PEREIRA, Matthew Robert Geoff SLIGHT, David Monroy FELIX, Xin Yue ZHU, Jonathan Tong Lok SNG, Arvin San Jose GARDIOLA, Stephen Francis HEFFERNAN, Christine Marie LYNCH, Wen Dong HUANG, Bruce Michael WALLS, Jeremy Owen YOUNG, Tony William SPEAR, Jake Baker HOCKING, Melissa Catherine BORNHOLDT
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Patent number: 12102764Abstract: A respiratory mask system includes a mask interface and a headgear assembly. The headgear assembly is adjustable and comprised of an elastic portion, a non-elastic portion and a restriction mechanism configured to provide a force resisting movement of the non-elastic portion when the elastic portion is extended. There is a support beam coupled to the non-elastic portion and extending along a portion of the headgear that is curved along its longitudinal extent. In this way particular seal modules can be comfortably fitted to a user and any blow off force is mitigated. A particular example of the respiratory mask system includes provision for removable attachment between the seal and a mask frame, the mask frame and a yoke of the headgear; and between a conduit and the mask frame.Type: GrantFiled: June 26, 2018Date of Patent: October 1, 2024Assignee: Fisher & Paykel Healthcare LimitedInventors: Christopher Gareth Sims, Fadi Karim Moh'd Mashal, Vitaly Kapelevich, Mark Arvind McLaren, Silas Sao Jin Siew, Jonathan Mark Downey, Christopher Michael Wong, Matthew Aaron Bradley, Janine Elizabeth Collins, Dillan Patel, Steve Thomas, Chris Onin Limpin Hipolito, Priyanka Ferdinand Pereira, Matthew Robert Geoff Slight, David Monroy Felix, Xin Yue Zhu, Jonathan Tong Lok Sng, Arvin San Jose Gardiola, Stephen Francis Heffernan, Christine Marie Lynch, Wen Dong Huang, Bruce Michael Walls, Jeremy Owen Young, Tony William Spear, Jake Baker Hocking, Melissa Catherine Bornholdt
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Patent number: 12105693Abstract: A performance measurement indexing system indexes a data store containing data entries indicative of message processing by an application. The application includes a plurality of checkpoints, and the data store contains data logged upon each message traversing the checkpoints in the application. The performance measurement indexing system determines which data entries relate to messages that satisfy a delay condition, and limits queries run on the data store to those data entries, thereby increasing the speed and efficiency with which queries can be serviced.Type: GrantFiled: August 29, 2023Date of Patent: October 1, 2024Assignee: Chicago Mercantile Exchange Inc.Inventors: Kyle Dennis Kavanagh, José Antonio Acuña-Rohter, David Michael Wong
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Patent number: 12084075Abstract: In accordance with an exemplary embodiment, methods and systems are provided for controlling steering of an autonomous vehicle. The method includes: operating, by a processor, the autonomous vehicle in a semi-automated mode; receiving, by the processor, driver input including a measured driver torque; receiving, by the processor, threat data; determining, by the processor, a steering command bias based on an impedance relation, impedance parameters, the measured driver torque, and the threat data; determining, by the processor, a reference angle based on the steering command bias and a desired angle; and generating, by the processor, control data to control the steering of the autonomous vehicle based on the reference angle.Type: GrantFiled: December 1, 2021Date of Patent: September 10, 2024Assignee: GM GLOBAL TECHNOLOGY OPERATIONS LLCInventors: Jimmy Lu, Reza Zarringhalam, Kin Man Michael Wong, Jackson Barry McGrory, Mehdi Abroshan, Puneet Bagga, Zhi Li
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Publication number: 20240256238Abstract: A monitoring system monitors processing of incoming messages by an application, and logs data related to performance of the application. The application includes a plurality of checkpoints, and the monitoring system logs data upon each message traversing the checkpoints in the application. The monitoring system is configured to dynamically modify checkpoints within the application based on latency detection of portions of the application, resulting in improved granularity/resolution of the data collected from congested portions of the application, and reducing the performance penalty of the monitoring system from portions of the application that are not congested.Type: ApplicationFiled: April 2, 2024Publication date: August 1, 2024Applicant: Chicago Mercantile Exchange Inc.Inventors: Kyle Dennis Kavanagh, José Antonio Acuña-Rohter, David Michael Wong
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Publication number: 20240221968Abstract: A method for producing Actinium-225 from proton spallation of thorium targets via a radium generator. The method includes dissolving a thorium target into a thorium solution, evaporating the thorium solution thereby resulting in a dried thorium salt, reconstituting the dried thorium salt in sulfuric acid for formation of neutral thorium species, passing neutral thorium species through a cation exchange chromatography column for bulk thorium removal, conducting extraction chromatography in a mixed resin bed thereby eluting radium, evaporating the radium containing eluent, reconstituting dried radium, and conducting extraction chromatography to elute a purified radium fraction thereby constructing a radium generator.Type: ApplicationFiled: December 27, 2023Publication date: July 4, 2024Inventors: Patrick CAUSEY, Blake TAMBOLINE, Michael WONG, Alexander K. LEE
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Publication number: 20240199088Abstract: Methods and systems are provided for alerting a driver to take control of a vehicle. In one embodiment, a method includes: determining, by a processor, a driver alertness level based on a weighted summation of a first set of feature data; determining, by the processor, a required alertness level based on a weighted summation of a second set of feature data; determining, by the processor, an escalation index based on the driver alertness level and the required alertness level; and generating, by the processor, alert notification data based on the escalation index.Type: ApplicationFiled: December 15, 2022Publication date: June 20, 2024Applicant: GM GLOBAL TECHNOLOGY OPERATIONS LLCInventors: Parisa Mahvelatishamsabadi, Milad Jalaliyazdi, Zhi Li, Mohammadali Shahriari, Peitong Hu, Kin Man Michael Wong
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Publication number: 20240195739Abstract: Disclosed is a self-contained mesh radio extension unit, comprising a receiving sleeve having an open volume and a first data connector for communicative coupling to a communication device or cellular phone inserted in the open volume. A low-gain internal antenna and a high-gain external antenna are coupled to a digital data link (DDL) with a first DDL operating frequency. The DDL provides bidirectional internet protocol (IP) connectivity between the first data connector and a peer-to-peer meshed communication network, controlling one or more of the antennae as transceivers at the first DDL operating frequency. An integrated power supply system powers the DDL and includes a rechargeable internal battery and an external power interface. A control system automatically routes IP packets received or transmitted by the DDL and includes a network address translation (NAT) router and an IP addressing service for assigning and tracking IP addresses across the peer-to-peer meshed communication network.Type: ApplicationFiled: January 12, 2024Publication date: June 13, 2024Applicant: Fenix Group, Inc.Inventors: Matthew Drapp, Stefan Schaner, Michael Wong
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Patent number: 12005933Abstract: In accordance with an exemplary embodiment, methods and systems are provided for controlling steering of an autonomous vehicle. The method includes: operating, by a processor, the autonomous vehicle in a path-based automated driving assist mode; receiving, by the processor, driver input including a driver torque; classifying, by the processor, an operation mode based on a type of the path-based automated driving assist mode; determining, by the processor, an override threshold for overriding the path-based automated driving assist mode on a first lateral side of the autonomous vehicle based on the operation mode; determining, by the processor, a driver override status based on the override torque threshold; and generating, by the processor, control signals to control the steering of the autonomous vehicle based on the driver override status and the driver torque.Type: GrantFiled: November 30, 2021Date of Patent: June 11, 2024Assignee: GM GLOBAL TECHNOLOGY OPERATIONS LLCInventors: Kin Man Michael Wong, Matthew P Kempeinen, Jimmy Lu, Brian Porto, Reza Zarringhalam
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Patent number: 11972239Abstract: A monitoring system monitors processing of incoming messages by an application, and logs data related to performance of the application. The application includes a plurality of checkpoints, and the monitoring system logs data upon each message traversing the checkpoints in the application. The monitoring system is configured to dynamically modify checkpoints within the application based on latency detection of portions of the application, resulting in improved granularity/resolution of the data collected from congested portions of the application, and reducing the performance penalty of the monitoring system from portions of the application that are not congested.Type: GrantFiled: October 31, 2022Date of Patent: April 30, 2024Assignee: Chicago Mercantile Exchange Inc.Inventors: Kyle Dennis Kavanagh, José Antonio Acuña-Rohter, David Michael Wong
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Publication number: 20240018258Abstract: CD47+ disease cells such as cancer cells are treated using a combination of CD47 blocking agent and a CD38 antibody such as daratumumab. The anti-cancer effect of SIRP?Fc is enhanced in the presence of daratumumab. Specific combinations include SIRP?Fc forms that comprise an Fc that is either IgG1 or IgG4 isotype. These combinations are useful particularly to treat blood cancers including lymphomas, leukemias and myelomas.Type: ApplicationFiled: August 30, 2023Publication date: January 18, 2024Applicant: Pfizer Inc.Inventors: Gloria Hoi Ying LIN, Natasja Nielsen VILLER, Mark Michael WONG, Jeffrey Todd WINSTON, Robert Adam UGER
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Patent number: 11877353Abstract: Disclosed is a self-contained mesh radio extension unit, comprising a receiving sleeve having an open volume and a first data connector for communicative coupling to a communication device or cellular phone inserted in the open volume. A low-gain internal antenna and a high-gain external antenna are coupled to a digital data link (DDL) with a first DDL operating frequency. The DDL provides bidirectional internet protocol (IP) connectivity between the first data connector and a peer-to-peer meshed communication network, controlling one or more of the antennae as transceivers at the first DDL operating frequency. An integrated power supply system powers the DDL and includes a rechargeable internal battery and an external power interface. A control system automatically routes IP packets received or transmitted by the DDL and includes a network address translation (NAT) router and an IP addressing service for assigning and tracking IP addresses across the peer-to-peer meshed communication network.Type: GrantFiled: August 11, 2021Date of Patent: January 16, 2024Assignee: Fenix Group, Inc.Inventors: Matthew Drapp, Stefan Schaner, Michael Wong