Abstract: Compounds for use in treating or preventing human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following formula (I) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2, L, W1, W2, X, Y, and Z are as defined herein. Methods associated with the preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: The description relates to automated binary code summarization. In one example, a binary code summarization tool receives binary code and combines the received binary code with natural language in a prompt for a large language model (LLM). The binary code summarization tool receives a semantic summarization from the LLM relating to the received binary code and evaluates the new semantic summarization for malicious functionality in the received binary code.

Abstract: Antigen binding molecules (ABMs) comprising Fab domains in non-native configurations, ABM conjugates comprising the ABMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the ABMs and ABM conjugates, methods of using the ABMs, ABM conjugates and pharmaceutical compositions for treating cancer, nucleic acids encoding the ABMs, cells engineered to express the ABMs, and methods of producing ABMs.

Abstract: Systems, methods, and computer program products are provided for saving memory during training of knowledge graph neural networks. The method includes receiving a training dataset including a first set of knowledge graph embeddings associated with a plurality of entities for a first layer of a knowledge graph, inputting the training dataset into a knowledge graph neural network to generate at least one further set of knowledge graph embeddings associated with the plurality of entities for at least one further layer of the knowledge graph, quantizing the at least one further set of knowledge graph embeddings to provide at least one set of quantized knowledge graph embeddings, storing the at least one set of quantized knowledge graph embeddings in a memory, and dequantizing the at least one set of quantized knowledge graph embeddings to provide at least one set of dequantized knowledge graph embeddings.

Abstract: Systems, methods, and computer readable media are described herein that use a user-agent-based non-extractable cryptographic keypair to generate a cryptographic proof containing a device fingerprint that an authentication system can use to subsequently identify and/or register a known device. Specifically, the systems disclosed herein may generate the device's “fingerprint” in an isolated and secured environment. Although the private key cannot be extracted from the isolated and secured environment, the authentication system can verify the truthfulness of the device's identity. This cryptographic “fingerprint,” in concert with a synchronous authentication system, has the ability to essentially eliminate authentication phishing.

Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, Ebola, Zika, West Nile, Dengue, and HCV.

Abstract: Embodiments described herein relate to methods of recycling battery waste. In some aspects, a method can include applying a first heat treatment at a temperature of between about 100° C. and about 700° C. to the battery waste, the first heat treatment decomposing at least about 80 wt % of the binder, separating the electrode material from the current collector, and applying a second heat treatment at a temperature between about 400° C. and about 1,200° C. to the electrode material to produce a regenerated electrode material, the second heat treatment decomposing at least 90 wt % of binder remaining in the electrode material to produce a regenerated electrode material. In some embodiments, the method can include applying a surface treatment to the electrode material to remove surface coatings and/or surface impurities from the electrode material. In some embodiments, the surface treatment can include applying a solvent to the electrode material.

Abstract: Data structures, methods and tiling engines for storing tiling data in memory wherein the tiles are grouped into tile groups and the primitives are grouped into primitive blocks. The methods include, for each tile group: determining, for each tile in the tile group, which primitives of each primitive block intersect that tile; storing in memory a variable length control data block for each primitive block that comprises at least one primitive that intersects at least one tile of the tile group; and storing in memory a control stream comprising a fixed sized primitive block entry for each primitive block that comprises at least one primitive that intersects at least one tile of the tile group, each primitive block entry identifying a location in memory of the control data block for the corresponding primitive block. Each primitive block entry may comprise valid tile information identifying which tiles of the tile group are valid for the corresponding primitive block.

Abstract: A tray for a seat of a passenger vehicle including: (a) a first article that is at least partially transparent to a wavelength or wavelength range within the visible spectrum of electromagnetic radiation comprising a first primary surface; and (b) a first display separated from an external environment by the first article, the first display, when activated, at least partially visible through the first article from the external environment. A seat of a passenger vehicle including a seatback and the tray coupled to the seatback. The tray can be manipulable to, from, and between a stowed position and a deployed position. The first display is activated when the tray is in the deployed position. The tray can include a second display that is activated when the tray is in the stowed position to be viewable by a passenger rearward of the seatback to which the tray is coupled.

Abstract: The present invention pertains to the pharmaceutical field, and particularly relates to a pharmaceutical combination comprising a Bcl-2 inhibitor or a Bcl-2/Bcl-xL inhibitor and one or more anticancer reagents, and the use of the combination to treat a disease such as cancer, specifically acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL) or multiple myeloma (MM) resistant or insensitive to Bcl-2 inhibitors and/or carrying Bcl-2 mutation and/or TP53 mutation. The invention also relates to a pharmaceutical composition or kit comprising the combination.

Abstract: Some examples of the disclosure are directed to systems and methods for selectively displaying an image of a portion of a physical environment of an electronic device with enhanced visibility. In some examples, the image is displayed overlaid on a portion of a view of the physical environment. In some examples, the electronic device displays the image in accordance with one or more first criteria being satisfied. In some examples, the electronic device forgoes displaying the image in accordance with the one or more criteria not being satisfied.

Abstract: A modular programmable widget for a vehicle includes a front housing and a back housing defining an enclosure; one or more physical controls provided on a front face of the enclosure; a contact pad exposed by the enclosure for electrical connection to a dock, the contact pad providing for transmission of data and power between the modular programmable widget and the dock; and one or more features for mechanical connection and securing of the modular programmable widget to the dock.

Abstract: A charging connector adapter is nested within a holster of an electric vehicle supply equipment (EVSE). If the adapter is to be used, the EVSE automatically locks the charging connector to the charging connector adapter and unlocks the charging connector adapter from the holster of the EVSE thereby allowing the charging cable with the charging connector adapter to be removed from the holster and used for connecting the charging connector adapter to an inlet of an electric vehicle. When the charging connector adapter is inserted back into the holster, the EVSE locks the charging connector to the holster and unlocks the charging connector from the charging connector adapter.

Abstract: A dock for receiving modular programmable widgets includes a body defining a securing channel for receiving the modular programmable widgets, the securing channel being sized to conform with a profile of an attachment body of the rear of the modular programmable widgets; a plurality of dock connectors configured to receive contact pads of the modular programmable widgets; and locators defined by the securing channel into the securing channel to aid in placement of the modular programmable widgets in positions where the contact pads of the modular programmable widgets are aligned with one of the dock connectors.

Abstract: A storage system for a plane fuselage including at least one storage unit defining an enclosed cargo storage space. At least one monitoring module is disposed proximate the at least one storage unit. The at least one monitoring module is configured to detect a condition within or proximate the at least one storage unit that includes at least one of a temperature, a fire condition, a water leakage, a gas leakage, a chemical leakage, an explosive condition, or a movement of the at least one storage unit. At least one status communication device is in communication with the at least one monitoring module and is configured to alert a user of the detected condition by the at least one monitoring module.

Abstract: A physical toggle button located in a cabin of a vehicle receives input indicating a change in state of the physical toggle button from a first mode in which a plurality of functions of smart home devices are set to a first state to a second mode in which the plurality of functions of the smart home devices are set to a second state. Using a telematics control module of the vehicle, a state change request is sent indicating the change in state to a cloud service maintaining a function mapping including information for setting the plurality of functions between the first state and the second state.

Abstract: The present disclosure provides methods for reducing methane emissions from a ruminant comprising administering to the ruminant a composition comprising a fungal strain, wherein the fungal strain comprises a vanadium-dependent haloperoxidase (VHPO) such as Curvularia sp. strain 4388 (NMI Accession No. V22/011149). The disclosure also provides a cell or a biologically pure culture of Curvularia sp. strain 4388 (NMI Accession No. V22/011149) or a mutant thereof having all identifying characteristics of the strain.

Abstract: Some embodiments relate to a chassis module for a chassis, the chassis module includes an insertion element configured to slide into one of a plurality of receiving compartments of a spine of the chassis. The insertion element includes a first electrical contact and a second electrical contact. The first electrical contact is on a first side of the insertion element and is configured to physically contact a first bus bar of the spine. The second electrical contact is on a second side of the insertion element opposite the first side. The second electrical contact is configured to contact a second bus bar of the spine.

Abstract: Techniques for altering default language, in system outputs, with language included in system inputs are described. A system may determine a word(s) in user inputs, associated with a particular user identifier, correspond to but are not identical to a word(s) in system outputs. The system may store an association between the user identifier, the word(s) in the user inputs, and the word(s) in the system outputs. Thereafter, when the system is generates a response to a user input, the system may replace the word(s), traditionally in the system outputs, with the word(s) that was present in previous user inputs. Such processing may further be tailored to a natural language intent.

Abstract: A reusable shipper container has a container body with a payload chamber for holding goods and a lid operable to access the payload chamber. The reusable shipper container also has one or more sensors in the payload chamber to senses a humidity or temperature of the payload chamber or the goods. The reusable shipper container also has a tablet display screen detachably coupled to the container body that wirelessly communicates with the sensors in the payload chamber and that displays one or more of an electronic shipping label, packing instructions, return instructions and maintenance status.