Patents by Inventor Michel Bernier

Michel Bernier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10772849
    Abstract: This disclosure concerns the discovery of the use of fenoterol analogues for regulating cannabinoid (CB) receptor activity-related disorders and disease, such as dysregulated CB receptors, including treating a disorder or disease, such as a glioblastoma, hepatocellular carcinoma, liver cancer, colon cancer, and/or lung cancer, which is associated with altered cannabinoid receptor activity. In one example, the method includes administering to a subject having or at risk of developing a disorder or disease regulated by CB receptor activity an effective amount of a fenoterol analogue to reduce one or more symptoms associated with the disorder or disease regulated by CB receptor activity.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: September 15, 2020
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Irving W. Wainer, Michel Bernier, Rajib K. Paul
  • Publication number: 20200247383
    Abstract: Monitoring is provided for a drive belt of a continuously variable transmission (CVT) mounted in a vehicle having a motor driving the CVT. A rotational speed of the motor and a power level of the motor are sensed. An abuse indicator for the drive belt is set when, concurrently, the rotational speed of the motor increases at a rate that exceeds a change threshold and the power level of the motor exceeds a power threshold. A level of abuse of the drive belt is calculated based on a speed of the vehicle and on a drive belt temperature. Damage to the drive belt may be prevented by limiting a power output of the motor when an accumulated level of abuse exceeds an abuse threshold. A vehicle having an electronic control unit configured to perform the method is also disclosed.
    Type: Application
    Filed: January 31, 2020
    Publication date: August 6, 2020
    Inventors: Xavier-Pierre AITCIN, Bruno SCHUEHMACHER, Marc GIGUERE, Michel BERNIER
  • Publication number: 20200197332
    Abstract: This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogues for the treatment of a tumor expressing a ?2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a ?2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analogue or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject.
    Type: Application
    Filed: March 2, 2020
    Publication date: June 25, 2020
    Applicants: The USA, as represented by the Secretary, Department of Health and Human Services, SRI International
    Inventors: Irving W. Wainer, Michel Bernier, Lawrence Robert Toll, Lucita Arenas Jimenez
  • Patent number: 10617654
    Abstract: This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogues for the treatment of a tumor expressing a ?2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a ?2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analogue or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: April 14, 2020
    Assignees: The USA, as represented by the Secretary, Department of Health and Human Services, SRI International
    Inventors: Irving W. Wainer, Michel Bernier, Lawrence Robert Toll, Lucita Arenas Jimenez
  • Publication number: 20200080504
    Abstract: An internal combustion engine (ICE) includes a crankshaft, a cylinder head defining in part a variable combustion chamber of the ICE, a direct fuel injector mounted on the cylinder head, a power source, an electric turning machine (ETM) rotating the crankshaft, an absolute position sensor providing an indication of an angular position of a rotor of the ETM, and an engine control unit (ECU) operatively connected to the absolute position sensor. The ECU controls a delivery of electric power from the power source to the ETM based on the angular position of the rotor of the ETM and causes the direct fuel injector to inject fuel directly in the combustion chamber at a time selected based on the angular position reached by the rotor of the ETM.
    Type: Application
    Filed: November 12, 2019
    Publication date: March 12, 2020
    Inventors: Normand LEBREUX, Michel BERNIER, David MONFETTE, Bruno SCHUEHMACHER
  • Publication number: 20200080505
    Abstract: A method for controlling delivery of electric power between a power source and an electric turning machine (ETM) comprises applying a start signal to a start-up power electronic switch to cause turning on of the start-up power electronic switch and to allow delivery of electric power from the power source to the ETM via the start-up power electronic switch. A recharge signal is applied to a run-time power electronic switch to cause turning on of the run-time power electronic switch for delivery of electric power from the ETM to the power source via the run-time power electronic switch. A circuit comprises a discharging circuit including the start-up power electronic switch for delivering the electric power when the start-up power electronic switch is turned on. A charging circuit includes the run-time power electronic switch for delivering the electric power when the run-time power electronic switch is turned on.
    Type: Application
    Filed: November 12, 2019
    Publication date: March 12, 2020
    Inventors: Normand Lebreux, Michel Bernier, David Monfette, Bruno Schuehmacher
  • Publication number: 20200080503
    Abstract: A method for starting an internal combustion engine (ICE) having a crankshaft and an electric turning machine (ETM) operatively connected to the crankshaft comprises energizing an absolute position sensor adapted for providing an indication of an angular position of a rotor of the ETM and applying a current to the ETM to generate a sufficient torque to rotate the crankshaft.
    Type: Application
    Filed: November 12, 2019
    Publication date: March 12, 2020
    Inventors: Normand LEBREUX, Michel BERNIER, David MONFETTE, Bruno SCHUEHMACHER
  • Publication number: 20200056559
    Abstract: A method and a system for starting an internal combustion engine (ICE) having a crankshaft and an electric turning machine (ETM) operatively connected to the crankshaft are disclosed. An absolute angular position of the crankshaft related to a top dead center position of a piston in a combustion chamber of the ICE is determined. Electric power is delivered to the ETM at a first level to rotate the crankshaft. Electric power is then delivered to the ETM at a second level greater than the first level when the piston reaches a predetermined position before the TDC position. Fuel is injected in the combustion chamber after the piston has passed beyond the TDC position. The fuel is then ignited. In an implementation, the ICE is started in less than 110 degrees of rotation of the crankshaft.
    Type: Application
    Filed: May 12, 2017
    Publication date: February 20, 2020
    Inventors: Normand LEBREUX, Michel BERNIER, David MONFETTE, Bruno SCHUEHMACHER
  • Publication number: 20200030261
    Abstract: This disclosure concerns the discovery of the use of fenoterol analogues for regulating cannabinoid (CB) receptor activity-related disorders and disease, such as dysregulated CB receptors, including treating a disorder or disease, such as a glioblastoma, hepatocellular carcinoma, liver cancer, colon cancer, and/or lung cancer, which is associated with altered cannabinoid receptor activity. In one example, the method includes administering to a subject having or at risk of developing a disorder or disease regulated by CB receptor activity an effective amount of a fenoterol analogue to reduce one or more symptoms associated with the disorder or disease regulated by CB receptor activity.
    Type: Application
    Filed: October 11, 2019
    Publication date: January 30, 2020
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Servic
    Inventors: Irving W. Wainer, Michel Bernier, Rajib K. Paul
  • Patent number: 10485771
    Abstract: This disclosure concerns the discovery of the use of fenoterol analogues for regulating cannabinoid (CB) receptor activity-related disorders and disease, such as dysregulated CB receptors, including treating a disorder or disease, such as a glioblastoma, hepatocellular carcinoma, liver cancer, colon cancer, and/or lung cancer, which is associated with altered cannabinoid receptor activity. In one example, the method includes administering to a subject having or at risk of developing a disorder or disease regulated by CB receptor activity an effective amount of a fenoterol analogue to reduce one or more symptoms associated with the disorder or disease regulated by CB receptor activity.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: November 26, 2019
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Irving W. Wainer, Michel Bernier, Rajib K. Paul
  • Patent number: 10450968
    Abstract: A snowmobile includes a frame with a tunnel, a fuel tank disposed thereon and an engine connected thereto. A throttle body fluidly communicates with the engine. A throttle valve is disposed in the throttle body for regulating fluid flow through the throttle body into the engine, a position of the throttle valve being movable between an open position and a closed position. A throttle operator connected to the frame to control the position of throttle valve is moveable between an idle position and a drive position. A throttle valve actuator operatively connected to the throttle valve and the throttle operator controls a position of the throttle valve based at least in part on the throttle operator position, the throttle valve actuator being an electric throttle valve actuator and disposed longitudinally between the fuel tank and the engine. Vehicles and methods of operating the vehicles are also disclosed.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: October 22, 2019
    Assignee: BOMBARDIER RECREATIONAL PRODUCTS INC.
    Inventors: Michel Bernier, Benoit Pion, Pierre-Luc Milot, Jean-Sebastien Pard, Michel Lefebvre
  • Patent number: 10337078
    Abstract: Described are solid agglomerates of fine metal particles and methods for manufacturing same. A liquid oily lubricant is used in the manufacture of the solid agglomerates. The manufacturing comprises blending fine metal particles with the liquid oily lubricant and compacting the oily metallic mixture obtained to desired solid form. Advantageously, the solid agglomerates possess a desirable density, a suitable resistance to crumbling and dusting during handling, and they can resist to high temperature and to humidity. Solid agglomerated metal products, according to the invention, may be useful for different purposes such as quality charge material for steel plants, blast furnaces and foundries.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: July 2, 2019
    Assignee: GESTION MCMARLAND INC.
    Inventors: Michel Beaudoin, Raymond Bernier, Martin Gagne, Marie-Josee Robichaud
  • Publication number: 20190153989
    Abstract: A method for operating an electric turning machine (ETM) operatively connected to an internal combustion engine (ICE) are disclosed. An engine control unit (ECU) controls the ETM to operate as a motor with a first control strategy and as a generator with a second control strategy. The second control strategy is distinct from the first control strategy. The ECU controls switching the operation of the ETM from the first control strategy to the second control strategy when a sensor senses that a rotational speed of the ICE is equal to or above a minimum revolution threshold.
    Type: Application
    Filed: January 22, 2019
    Publication date: May 23, 2019
    Inventors: Normand LEBREUX, Michel BERNIER, Jasmin ROULEAU, David MONFETTE
  • Publication number: 20190153988
    Abstract: A system for starting an internal combustion engine (ICE) having a crankshaft is introduced. An electric turning machine (ETM) is co-axially mounted to the crankshaft. The crankshaft is rotated using a recoil starter for starting the ICE. A position sensor detects the rotation of the crankshaft. While the crankshaft is rotating, an engine control unit (ECU) operatively connected to the position sensor controls a delivery of electric power from a power source to the ETM for starting the ICE. An ICE integrating the system for starting the ICE and the crankshaft with a cylinder, a cylinder head connected to the cylinder, and a piston connected to the crankshaft and disposed in the cylinder to define a variable volume combustion chamber between the piston and the cylinder head is also disclosed.
    Type: Application
    Filed: January 22, 2019
    Publication date: May 23, 2019
    Inventors: Normand LEBREUX, Michel BERNIER, Jasmin ROULEAU, David MONFETTE
  • Publication number: 20190153990
    Abstract: A system for operating an electric turning machine (ETM) operatively connected to an internal combustion engine (ICE) are disclosed. An engine control unit (ECU) controls the ETM to operate as a motor with a first control strategy and as a generator with a second control strategy. The second control strategy is distinct from the first control strategy. The ECU controls switching the operation of the ETM from the first control strategy to the second control strategy when a sensor senses that a rotational speed of the ICE is equal to or above a minimum revolution threshold.
    Type: Application
    Filed: January 22, 2019
    Publication date: May 23, 2019
    Inventors: Normand LEBREUX, Michel BERNIER, Jasmin ROULEAU, David MONFETTE
  • Publication number: 20190008802
    Abstract: This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogues for the treatment of a tumor expressing a ?2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a ?2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analogue or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject.
    Type: Application
    Filed: September 12, 2018
    Publication date: January 10, 2019
    Applicants: The USA, as represented by the Secretary, Departme nt of Health and Human Services, SRI International
    Inventors: Irving W. Wainer, Michel Bernier, Lawrence Robert Toll, Lucita Arenas Jimenez
  • Publication number: 20190000781
    Abstract: This disclosure concerns the discovery of the use of fenoterol analogues for regulating cannabinoid (CB) receptor activity-related disorders and disease, such as dysregulated CB receptors, including treating a disorder or disease, such as a glioblastoma, hepatocellular carcinoma, liver cancer, colon cancer, and/or lung cancer, which is associated with altered cannabinoid receptor activity. In one example, the method includes administering to a subject having or at risk of developing a disorder or disease regulated by CB receptor activity an effective amount of a fenoterol analogue to reduce one or more symptoms associated with the disorder or disease regulated by CB receptor activity.
    Type: Application
    Filed: September 12, 2018
    Publication date: January 3, 2019
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Serv
    Inventors: Irving W. Wainer, Michel Bernier, Rajib K. Paul
  • Publication number: 20180347534
    Abstract: A method and a system for operating an electric turning machine (ETM) operatively connected to an internal combustion engine (ICE) are disclosed. The ETM operates as a motor with a first control strategy and as a generator with a second control strategy, the second control strategy being distinct from the first control strategy. The system comprises an engine control unit adapted for controlling an operation of the ETM according to the first and second control strategies. Electric and assisted start procedures are available for starting the ICE by delivering electric power from a power source to the ETM which is co-axially mounted to a crankshaft of the ICE. Assisted start includes delivering the electric power to the ETM while a recoil starter is used to rotate the crankshaft. A manual start procedure is also available. The power source is charged by the ETM when the ICE is running.
    Type: Application
    Filed: November 11, 2016
    Publication date: December 6, 2018
    Inventors: Normand LEBREUX, Michel BERNIER, Jasmin ROULEAU, David MONFETTE
  • Patent number: 10130593
    Abstract: This disclosure concerns the discovery of the use of fenoterol analogs for regulating cannabinoid (CB) receptor activity-related disorders and disease, such as dysregulated CB receptors, including treating a disorder or disease, such as a glioblastoma, hepatocellular carcinoma, liver cancer, colon cancer, and/or lung cancer, which is associated with altered cannabinoid receptor activity. In one example, the method includes administering to a subject having or at risk of developing a disorder or disease regulated by CB receptor activity an effective amount of a fenoterol analog to reduce one or more symptoms associated with the disorder or disease regulated by CB receptor activity.
    Type: Grant
    Filed: August 1, 2016
    Date of Patent: November 20, 2018
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Irving William Wainer, Michel Bernier, Rajib Kumar Paul
  • Patent number: 10130594
    Abstract: This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogs for the treatment of a tumor expressing a ?2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a ?2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analog or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject.
    Type: Grant
    Filed: September 22, 2016
    Date of Patent: November 20, 2018
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, SRI International
    Inventors: Irving W. Wainer, Michel Bernier, Lawrence Robert Toll, Lucita Arenas Jimenez