Patents by Inventor Michele Cargill

Michele Cargill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETIC POLYMORPHISMS ASSOCIATED WITH RHEUMATOID ARTHRITIS, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20140234291
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with rheumatoid arthritis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: November 15, 2013
    Publication date: August 21, 2014
    Applicant: Celera Corporation
    Inventors: Michele CARGILL, Ann B. BEGOVICH, Victoria CARLTON, Steven J. SCHRODI, Heather C. ALEXANDER
  • GENETIC POLYMORPHISMS ASSOCIATED WITH CARDIOVASCULAR DISORDERS AND DRUG RESPONSE, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20140221484
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with cardiovascular disorders, particularly acute coronary events such as myocardial infarction and stroke, and genetic polymorphisms that are associated with responsiveness of an individual to treatment of cardiovascular disorders with statin. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: October 3, 2013
    Publication date: August 7, 2014
    Applicants: BRISTOL-MYERS SQUIBB COMPANY, CELERA CORPORATION
    Inventors: Michele CARGILL, Olga IAKOUBOVA, James J. DEVLIN, Zenta TSUCHIHASHI, Peter SHAW, Lynn Marie PLOUGHMAN, Kim E. ZERBA, Koustubh RANADE, Todd KIRCHGESSNER
  • GENETIC POLYMORPHISMS ASSOCIATED WITH ALZHEIMER'S DISEASE, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20140199290
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with Alzheimer's disease. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: November 14, 2013
    Publication date: July 17, 2014
    Applicant: CELERA CORPORATION
    Inventors: Andrew GRUPE, Yonghong LI, Michele CARGILL
  • GENETIC POLYMORPHISMS ASSOCIATED WITH LIVER FIBROSIS, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20140072957
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with liver fibrosis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: February 11, 2013
    Publication date: March 13, 2014
    Applicant: Celera Corporation
    Inventors: Hongjin HUANG, Michele CARGILL
  • GENETIC POLYMORPHISMS ASSOCIATED WITH LIVER FIBROSIS, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20130029327
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with liver fibrosis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: May 25, 2012
    Publication date: January 31, 2013
    Applicant: CELERA CORPORATION
    Inventors: Hongjin HUANG, Ramasubbu VENKATESH, Michele CARGILL
  • METHODS AND SYSTEMS FOR GENOMIC ANALYSIS USING ANCESTRAL DATA
    Publication number: 20130013217
    Abstract: The present disclosure provides methods and systems for assessing an individual's genotype correlations to a phenotype by analyzing the individual's genomic profile and using ancestral data to determine the correlations between genotypes and phenotypes.
    Type: Application
    Filed: September 12, 2012
    Publication date: January 10, 2013
    Applicant: NAVIGENICS, INC.
    Inventors: Dietrich A. STEPHAN, Jennifer Wessel, Michele Cargill, Eran Halperin
  • GENETIC POLYMORPHISMS ASSOCIATED WITH LIVER FIBROSIS METHODS OF DETECTION AND USES THEREOF
    Publication number: 20120276528
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with liver fibrosis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: October 27, 2011
    Publication date: November 1, 2012
    Applicant: CELERA CORPORATION
    Inventors: Michele CARGILL, Hongjin HUANG
  • Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof
    Patent number: 8211638
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with liver fibrosis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: July 3, 2012
    Assignee: Celera Corporation
    Inventors: Hongjin Huang, Ramasubbu Venkatesh, Michele Cargill
  • GENETIC POLYMORPHISMS ASSOCIATED WITH PSORIASIS, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20120082678
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: April 5, 2011
    Publication date: April 5, 2012
    Applicant: CELERA CORPORATION
    Inventors: Yonghong LI, Ann BEGOVICH, Monica CHANG, Michele CARGILL, Steven SCHRODI
  • GENETIC POLYMORPHISMS ASSOCIATED WITH PSORIASIS, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20120010274
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: July 1, 2011
    Publication date: January 12, 2012
    Applicant: CELERA CORPORATION
    Inventors: Ann BEGOVICH, Ellen BEASLEY, Michele CARGILL, Steven SCHRODI
  • Genetic polymorphisms associated with psoriasis, methods of detection and uses thereof
    Patent number: 7993833
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: August 9, 2011
    Assignee: Celera Corporation
    Inventors: Ann Begovich, Ellen Beasley, Michele Cargill, Steven Schrodi
  • GENETIC POLYMORPHISMS ASSOCIATED WITH LIVER FIBROSIS METHODS OF DETECTION AND USES THEREOF
    Publication number: 20110129831
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with liver fibrosis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: September 20, 2010
    Publication date: June 2, 2011
    Applicant: CELERA CORPORATION
    Inventors: Michele CARGILL, Hongjin HUANG
  • Genetic polymorphisms associated with psoriasis, methods of detection and uses thereof
    Patent number: 7947451
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: May 24, 2011
    Assignee: Celera Corporation
    Inventors: Yonghong Li, Ann Begovich, Monica Chang, Michele Cargill, Steven Schrodi
  • GENETIC ANALYSIS SYSTEMS AND METHODS
    Publication number: 20100293130
    Abstract: The present invention provides methods of determining a Genetic Composite Index score by assessing the association between an individual's genotype and at least one disease or condition. The assessment comprises comparing an individual's genomic profile with a database of medically relevant genetic variations that have been established to associate with at least one disease or condition.
    Type: Application
    Filed: November 30, 2007
    Publication date: November 18, 2010
    Inventors: Dietrich A. Stephan, Melissa Floren Filippone, Jennifer Wessel, Michele Cargill, Eran Halperin
  • Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof
    Patent number: 7811794
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with rheumatoid arthritis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: March 18, 2004
    Date of Patent: October 12, 2010
    Assignee: Celera Corporation
    Inventors: Michele Cargill, Ann Bethea Begovich, Heather Camille Alexander
  • GENETIC POLYMORPHISMS ASSOCIATED WITH RHEUMATOID ARTHRITIS, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20100215645
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with rheumatoid arthritis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: May 4, 2010
    Publication date: August 26, 2010
    Applicant: CELERA CORPORATION
    Inventors: Michele CARGILL, Ann Bethea BEGOVICH, Victoria Elizabeth Hope CARLTON, Steven Jon SCHRODI, Heather Camille ALEXANDER
  • GENETIC POLYMORPHISMS ASSOCIATED WITH LIVER FIBROSIS, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20100216154
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with liver fibrosis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: April 29, 2010
    Publication date: August 26, 2010
    Applicant: CELERA CORPORATION
    Inventors: Hongjin HUANG, Ramasubbu VENKATESH, Michele CARGILL
  • GENETIC POLYMORPHISMS ASSOCIATED WITH CARDIOVASCULAR DISORDERS AND DRUG RESPONSE, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20100190172
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with cardiovascular disorders, particularly acute coronary events such as myocardial infarction and stroke, and genetic polymorphisms that are associated with responsiveness of an individual to treatment of cardiovascular disorders with statin. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: January 6, 2010
    Publication date: July 29, 2010
    Applicant: CELERA CORPORATION
    Inventors: Michele CARGILL, Olga IAKOUBOVA, James J. DEVLIN, Zenta TSUCHIHASHI, Peter SHAW, Lynn Marie PLOUGHMAN, Kim E. ZERBA, Koustubh RANADE, Todd KIRCHGESSNER
  • Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof
    Patent number: 7727725
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with liver fibrosis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: April 26, 2007
    Date of Patent: June 1, 2010
    Assignee: Celera Corporation
    Inventors: Hongjin Huang, Ramasubbu Venkatesh, Michele Cargill
  • Methods and Systems for Incorporating Multiple Environmental and Genetic Risk Factors
    Publication number: 20100070455
    Abstract: The present disclosure provides methods and systems for incorporating multiple environmental and genetic risk factors into an individual's genomic profile. Methods include assessing the association between an individual's genotype and at least one disease or condition by incorporating multiple genetic risk factors, environmental risk factors, or a combination of both.
    Type: Application
    Filed: September 11, 2009
    Publication date: March 18, 2010
    Applicant: Navigenics, Inc.
    Inventors: Eran Halperin, Jennifer Wessel, Michele Cargill, Dietrich A. Stephan