Patents by Inventor Michele Cargill

Michele Cargill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETIC POLYMORPHISMS ASSOCIATED WITH CORONARY HEART DISEASE, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20090264453
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with coronary heart disease, and in particular MI, and response to drug treatment. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: April 27, 2009
    Publication date: October 22, 2009
    Applicant: CELERA CORPORATION
    Inventors: Dov SHIFFMAN, Michele CARGILL, James J. DEVLIN
  • GENETIC POLYMORPHISMS ASSOCIATED WITH ALZHEIMER'S DISEASE, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20090196875
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with Alzheimer's disease. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: January 12, 2009
    Publication date: August 6, 2009
    Applicant: CELERA CORPORATION
    Inventors: Michele CARGILL, Andrew GRUPE, Yonghong LI
  • GENETIC POLYMORPHISMS ASSOCIATED WITH MYOCARDIAL INFARCTION, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20090176235
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with myocardial infarction. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: December 18, 2008
    Publication date: July 9, 2009
    Applicant: CELERA CORPORATION
    Inventors: Michele CARGILL, James J. DEVLIN, Olga IAKOUBOVA
  • GENETIC POLYMORPHISMS ASSOCIATED WITH STROKE, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20090170111
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with vascular diseases, particularly stroke. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: December 22, 2008
    Publication date: July 2, 2009
    Applicant: CELERA CORPORATION
    Inventors: May M. LUKE, James J. DEVLIN, Michele CARGILL
  • GENETIC POLYMORPHISMS ASSOCIATED WITH PSORIASIS, METHODS OF DETECTION AND USES THEREOF
    Publication number: 20090162348
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: December 1, 2008
    Publication date: June 25, 2009
    Applicant: CELERA CORPORATION
    Inventors: Yonghong LI, Ann BEGOVICH, Monica CHANG, Michele CARGILL, Steven SCHRODI
  • Genetic polymorphisms associated with myocardial infarction, methods of detection and uses thereof
    Publication number: 20090118217
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with myocardial infarction. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: October 8, 2008
    Publication date: May 7, 2009
    Applicant: Celera Corporation
    Inventors: Michele Cargill, James J. Devlin, Olga Iakoubova
  • Methods and Systems for Genomic Analysis Using Ancestral Data
    Publication number: 20090099789
    Abstract: The present disclosure provides methods and systems for assessing an individual's genotype correlations to a phenotype by analyzing the individual's genomic profile and using ancestral data to determine the correlations between genotypes and phenotypes.
    Type: Application
    Filed: September 26, 2008
    Publication date: April 16, 2009
    Inventors: Dietrich A. STEPHAN, Jennifer Wessel, Michele Cargill, Eran Halperin
  • Genetic polymorphisms associated with myocardial infarction, methods of detection and uses thereof
    Patent number: 7482117
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with myocardial infarction. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: January 27, 2009
    Assignee: Celera Corporation
    Inventors: Michele Cargill, James J. Devlin, Olga Iakoubova
  • Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof
    Publication number: 20080299554
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with liver fibrosis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: April 26, 2007
    Publication date: December 4, 2008
    Applicant: APPLERA CORPORATION
    Inventors: Hongjin Huang, Ramasubbu Venkatesh, Michele Cargill
  • Genetic polymorphisms associated with myocardial infarction, methods of detection and uses thereof
    Publication number: 20080248476
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with myocardial infarction. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: October 23, 2007
    Publication date: October 9, 2008
    Applicant: APPLERA CORPORATION
    Inventors: Michele Cargill, James J. Devlin, Olga Iakoubova, Dov Shiffman
  • Genetic polymorphisms associated with psoriasis, methods of detection and uses thereof
    Publication number: 20080108713
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: August 31, 2007
    Publication date: May 8, 2008
    Applicant: APPLERA CORPORATION
    Inventors: Ann Begovich, Ellen Beasley, Michele Cargill, Steven Schrodi
  • Genetic polymorphisms associated with stroke, methods of detection and uses thereof
    Publication number: 20070059710
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with vascular diseases, particularly stroke. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: February 25, 2005
    Publication date: March 15, 2007
    Applicant: APPLERA CORPORATION
    Inventors: May Luke, James Devlin, Michele Cargill
  • Polymorphisms in nucleic acid molecules encoding human enzyme proteins, methods of detection and uses thereof
    Publication number: 20070054278
    Abstract: The present invention is based on the discovery of polymorphisms in enzyme genes and encoded enzyme protein variants. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: November 17, 2004
    Publication date: March 8, 2007
    Applicant: APPLERA CORPORATION
    Inventor: Michele Cargill
  • Genetic polymorphisms associated with myocardial infarction, methods of detection and uses thereof
    Publication number: 20070042382
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with myocardial infarction. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: March 10, 2004
    Publication date: February 22, 2007
    Applicant: APPLERA CORPORATION
    Inventors: Michele Cargill, James Devlin, Olga Iakoubova, Dov Shiffman
  • Genetic polymorphisms associated with stenosis, methods of detection and uses thereof
    Publication number: 20070031847
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with stenosis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: March 10, 2004
    Publication date: February 8, 2007
    Applicant: APPLERA CORPORATION
    Inventors: Michele Cargill, James Devlin, May Luke
  • Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof
    Publication number: 20070031848
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with rheumatoid arthritis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: March 18, 2004
    Publication date: February 8, 2007
    Applicant: APPLERA CORPORATION
    Inventors: Michele Cargill, Ann Begovich, Heather Alexander
  • Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof
    Publication number: 20070031846
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with rheumatoid arthritis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: January 30, 2004
    Publication date: February 8, 2007
    Applicant: APPLERA CORPORATION
    Inventors: Michele Cargill, Ann Begovich, Victoria Carlton, Steven Schrodi, Heather Alexander
  • Genetic polymorphisms associated with coronary heart disease, methods of detection and uses thereof
    Publication number: 20060228715
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with coronary heart disease, and in particular MI, and response to drug treatment. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: March 7, 2005
    Publication date: October 12, 2006
    Applicant: APPLERA CORPORATION
    Inventors: Dov Shiffman, Michele Cargill, James Devlin
  • Genetic polymorphisms associated with coronary heart disease, methods of detection and uses thereof
    Publication number: 20060223093
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with coronary heart disease and in particular stenosis and MI and response to drug treatment. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: March 13, 2006
    Publication date: October 5, 2006
    Applicant: APPLERA CORPORATION
    Inventors: May Luke, James Devlin, Dov Shiffman, Michele Cargill
  • Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof
    Publication number: 20060024700
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with liver fibrosis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: May 9, 2005
    Publication date: February 2, 2006
    Applicant: APPLERA CORPORATION
    Inventors: Michele Cargill, Hongjin Huang