Abstract: The present invention relates to an anastomotic device (10) comprising a first ring (20) having a first contact surface (21) and a second ring (30) having a second contact surface (31). The rings (20, 30) are suitable to be approached in the axial direction (X) such as to move said contact surfaces (21; 31) towards each other. The anastomotic device is characterized in that the contact surfaces (21, 31) have an undulated shape relative to a plane (?) perpendicular to the axis (X) of the rings (20, 30). According to another aspect thereof, the invention also relates to an apparatus (60) for the implantation of the anastomotic device (10). According to a further aspect thereof, the invention relates to a kit comprising an anastomotic device (10) and an apparatus (60) for the implantation of the same.

Abstract: An instrumentation for performing an endoluminal or transluminal anastomosis, comprises an anastomotic ring device including a proximal ring (5) having two guide wire seats (22) adapted to slidably receive two guide wires (1, 2) and a distal ring (6) having two guide wire seats (25) adapted to slidably receive the two guide wires (1, 2), the proximal ring 5 and the distal ring 6 being snap-connectable to each other, a surgical probe (7) comprising an elongate insertion shaft (30) and a probe head (32) adapted to be endoluminally advanced to a proximal tissue portion (3), the insertion shaft (30) defining guide wire canals (8, 9) extending into two guide wire exit openings (31) defined in the probe head (32) and adapted to deliver the distal ends (1?, 2?) of said guide wires (1, 2) to said proximal tissue portion (3).

Abstract: An anastomotic device (10) is suitable for approximating and keeping close to each other a first tissue portion (12) and a second tissue portion (14) intended to form an anastomosis. The anastomotic device (10) comprises an abutment portion (18) suitable for the abutment against a surface of the first tissue portion (12) and a locking portion (20) suitable for being placed opposite the abutment portion (18) with respect to the first and second tissue portion (12, 14). The locking portion (20) and the abutment portion (18) are mutually connectable through the first and second tissue portions approximated, to keep them connected. The anastomotic device (10) is suitable for being connected to a guide means comprising at least one guide wire (A, B).

Abstract: A surgical instrument, such as a surgical stapling instrument (1), comprises a tissue manipulating portion (2) which is intended to be introduced in the body of a patient, a handle portion (3) with an actuating mechanism (7) adapted to generate actuating movements for the actuation of the tissue manipulating portion (2) and comprising at least a pair of rotary output members (33; 40) and an actuating transmission device (5, 5?; 6, 6?) connecting the actuating mechanism (7) of the handle portion (3) to the tissue manipulating portion (2) and comprising at least one pair of rotary rods (17, 17?; 19, 19?) for transmitting rotational actuating movements from the pair of rotary output members (33; 40) to the tissue manipulating portion (2). The actuating mechanism (7) comprises synchronization means (31, 32, 32?; 38, 20 39, 39?) which link the movements of the two rotary output members (33; 40) of the pair of rotary output members such that they counter-rotate at substantially the same speed.

Abstract: A positioning device for deploying at least one locking portion (20) of an anastomotic device (10) for drawing together a first tissue portion (12) and a second tissue portion (14) to be connected by means of anastomosis is suitable for sliding along a guide means comprising at least one guide wire (A, B) and comprises an elongated structure (50). A head (52) of the positioning device is suitable to be interference-inserted on a distal end of the elongated structure (50). The head (52) comprises elastic tabs (54) extending from a proximal end of the head and at least one channel (56) suitable for receiving a guide wire. The head (52) comprises a distal end defining a thrust surface (58) for a locking portion (20) of the anastomotic device (10).

Abstract: A surgical instrument (1) for performing controlled myotomies, particularly for performing internal anal sphincterotomies, comprises a proximal handle portion (2), an elongate insertion shaft (3) connected with the handle portion (2) and extending distally therefrom, a distal incision tip (4) arranged at a distal end of the insertion shaft (3) and adapted to incise tissue distally to the insertion shaft (3), a lateral incision member (5) arranged at the insertion shaft (3) and adapted to incise tissue laterally to the insertion shaft (3), wherein the lateral incision member (4) is movable from a rest position, in which it is retracted towards or inside the insertion shaft (3) and an operational position in which it protrudes laterally from the insertion shaft (3).

Abstract: Traction means (14) for excising a tissue sample comprising a distal portion (14a), comprising at least one clip (20) suitable for being fixed to at least one portion (12) of tissue to be excised and a proximal portion (14b) suitable for being subjected to traction. Said at least one clip (20) is suitable for being connected to a distal end (22a) of a suture (22) to pull the tissue to be excised, said suture (22) extending between said distal end (22a) and a proximal end corresponding to the proximal portion of said traction means (14). Moreover, said at least one clip (20) is connected to a ring (24) formed at a distal end (24a) of said suture (22) to pull the tissue to be excised.

Abstract: An Instrumentation for performing an endoluminal or transluminal anastomosis, comprises an anastomotic ring device including a proximal ring (5) having two guide wire seats (22) adapted to slidably receive two guide wires (1, 2) and a distal ring (6) having two guide wire seats (25) adapted to slidably receive the two guide wires, the proximal ring and the distal ring being snap-connectable to each other, a surgical probe (7) comprising an elongate insertion shaft (30) and a probe head (32) adapted to be endoluminally advanced to a proximal tissue portion (3), the insertion shaft defining guide wire canals (8, 9) extending into two guide wire exit openings (31) defined in the probe head and adapted to deliver the distal ends (1?, 2?) of said guide wires to said proximal tissue portion.

Abstract: A biopsy device includes a cutter defining a cutter lumen and a tissue sample holder for collecting tissue samples. In one example, the tissue sample holder has a rotatable manifold that is configured to redirect fluid from one axial direction to an opposite axial direction. The tissue sample holder also has a plurality of tissue sample trays through which fluid may be communicated. The tissue sample trays define chambers that are each configured to separately hold tissue samples. The tissue sample trays are removable relative to the manifold. A cup is configured to cover the manifold and trays. A tissue sample holder rotation mechanism is operable to rotate the manifold to successively index each chamber of the tissue sample trays with the cutter lumen. A feature may prevent rotation of the manifold when one part of the biopsy device is separated from another part of the biopsy device.

Abstract: An equipment to approximate tissue portions, which are intended to form an anastomosis comprises a guide means suitable for passing through a first tissue portion (12) and a second tissue portion (14) to be connected by anastomosis. This equipment further comprises an anastomotic device (10) to approximate the first tissue portion (12) and the second tissue portion (14) to be connected by anastomosis. The guide means consists of at least two guide wires (A, B), suitable for passing through the tissue portions to be connected, to receive and drag at least said anastomotic device (10) to approximate the first tissue portion (12) and the second tissue portion (14) to be connected by anastomosis. The guide wires (A, B) are located side by side to each other and are suitable for forming a loop which passes through the tissue portions to be connected.

Abstract: A device for drawing tissues together and creating an anastomosis comprises a main guide wire (66, 86) suitable to receive and draw anastomotic devices (10; 16; 24) in order to draw together portions (A; B) of tissues to be joined by means of anastomosis. The main guide wire (66, 86) is suitable to be shaped like an open ring crossing the portions (A, A?; B, B?) of tissues to be joined by means of anastomosis (66, 86), wherein the ends of the main guide wire (66, 86) are different and distinguishable from each other. The main guide wire (66, 86) has a tubular or hollow structure suitable to house at least one needle for a push or radiofrequency perforation of the tissues.

Abstract: A biopsy device may be used to obtain and store multiple tissue samples. The device permits the tissue samples to be stored in a sequenced fashion within a generally transparent tissue storage chamber disposed at a proximal end of the biopsy device. The tissue samples can be stored on flexible tissue sample strips arranged around the circumference of a rotating vacuum manifold disposed within the chamber.

Abstract: A biopsy device may be used to obtain and store multiple tissue samples. The device permits the tissue samples to be stored in a sequenced fashion within a generally transparent tissue storage chamber disposed at a proximal end of the biopsy device. The tissue samples can be stored on flexible tissue sample strips arranged around the circumference of a rotating vacuum manifold disposed within the chamber.

Abstract: 1. Instrumentation for carrying out a gastrointestinal bypass comprising: means (4, 6, 12) for creating a gastric sleeve (21, 22) from the lesser curvature (13) of the stomach (1), means for creating a gastrointestinal bypass involving said gastric sleeve (21, 22), in which said means for creating a gastrointestinal bypass include: means for creating a gastroenteroanastomosis (26) between two closely approximated gastric and intestinal tissue portions, maintaining the continuity of the intestinal duct after the creation of the gastroenteroanastomosis, means for creating an enteroenteroanastomosis (29) between two closely approximated tissue portions (27, 28) of the intestine, maintaining the continuity of the intestinal duct after the creation of the enteroenteroanastomosis (29), means for sectioning the intestine (20) between the gastroenteroanastomosis (26) and the enteroenteroanastomosis (29).

Abstract: A laparoscopic surgical access device comprises a first frame and a second frame having relative axial positions. A flexible and resilient iris valve is connected to the first and second frames and has a closed position and an opened position based on the relative angular position of the first and second frames. A lock is connected to the first and second frames, the lock being selectively operative to prevent relative rotational movement in a first rotational direction. One embodiment uses a ratchet and pawl mechanism operable with a control ring. Another embodiment uses a ratchet and pawl mechanism operable with a button. Yet another embodiment uses a wedge track and ball mechanism.

Abstract: A laparoscopic surgical access device comprises a first frame and a second frame having relative axial positions. A flexible and resilient iris valve is connected to the first and second frames and has a closed position and an opened position based on the relative angular position of the first and second frames. A lock is connected to the first and second frames, the lock being selectively operative to prevent relative rotational movement in a first rotational direction. One embodiment uses a ratchet and pawl mechanism operable with a control ring. Another embodiment uses a ratchet and pawl mechanism operable with a button. Yet another embodiment uses a wedge track and ball mechanism.

Abstract: An anastomotic device, particularly a circular stapler (10), comprises a handle (12) and a stem (14). A channel suitable to receive a guide wire at least partially develops along the length of the stapler. The stem (14) is made of a flexible material, such as to facilitate reaching the site requiring anastomosis. The circular stapler (10) comprises an anvil (16) suitable to be introduced on the free end of the stem (14). The anvil (16) comprises a channel (22) suitable to receive a guide wire (66) and extending along the anvil, and a portion (20) suitable to act as a striker against the wall of one of the portions (A; B) of the tissues to be joined.

Abstract: A diagnostic device for pathologies of tubular anatomical structures comprises a tubular elongated structure having a proximal end and a distal end. The distal end is suitable to be inserted in the tubular anatomical structure. The device includes a means for locally dilating the walls of the tubular anatomical structure that are associated with the distal end of said elongated structure. The means for locally dilating is movable between a closed position for introducing the device and at least one open position for viewing and evaluating the pathology. The device also has a control means on the proximal end of the elongated structure. The control means is operatively connected to the means for locally dilating, in order to move them between the closed position and the open position, and vice versa.

Abstract: A device for drawing tissues together and creating an anastomosis comprises a main guide wire (66, 86) suitable to receive and draw anastomotic devices (10; 16; 24) in order to draw together portions (A; B) of tissues to be joined by means of anastomosis. The main guide wire (66, 86) is suitable to be shaped like an open ring crossing the portions (A, A?; B, B?) of tissues to be joined by means of anastomosis (66, 86), wherein the ends of the main guide wire (66, 86) are different and distinguishable from each other. The main guide wire (66, 86) has a tubular or hollow structure suitable to house at least one needle for a push or radiofrequency perforation of the tissues.

Abstract: A surgical stapling instrument including a staple fastening assembly with a curved cartridge device and a curved anvil. The cartridge device has at least one curved open row of staples which are formed by a staple forming face of the anvil (12). The anvil can be moved relatively with respect to the cartridge device (10) the device further includes a handle in the proximal end region of the instrument and is operatively connected to the staple fastening assembly. A flexible backbone, preferably an endoscope, is arranged between the handle and the staple fastening assembly and guides force transmitters of the moving device and the staple driving device.