Abstract: A surgical stapling instrument (1) comprises a staple fastening assembly (2) including a curved cartridge device (10) and a curved anvil (12). The cartridge device (10) comprises at least one curved open row of staples which are formed by a staple forming face of the anvil (12). The anvil (12) can be moved relatively with respect to the cartridge device (10). A handle (4) in the proximal end region of the instrument is operatively connected to the staple fastening assembly (2). A flexible backbone, preferably an endoscope (6), is arranged between the handle (4) and the staple fastening assembly (2) and guides force transmitters (8, 9) of the moving device and the staple driving device.

Abstract: A surgical instrument (1) for performing controlled myotomies, particularly for performing internal anal sphincterotomies, comprises a proximal handle portion (2), an elongate insertion shaft (3) connected with the handle portion (2) and extending distally therefrom, a distal incision tip (4) arranged at a distal end of the insertion shaft (3) and adapted to incise tissue distally to the insertion shaft (3), a lateral incision member (5) arranged at the insertion shaft (3) and adapted to incise tissue laterally to the insertion shaft (3), wherein the lateral incision member (4) is movable from a rest position, in which it is retracted towards or inside the insertion shaft (3) and an operational position in which it protrudes laterally from the insertion shaft (3).

Abstract: An anastomotic device (10) is suitable for approximating and keeping close to each other a first tissue portion (12) and a second tissue portion (14) intended to form an anastomosis. The anastomotic device (10) comprises an abutment portion (18) suitable for the abutment against a surface of the first tissue portion (12) and a locking portion (20) suitable for being placed opposite the abutment portion (18) with respect to the first and second tissue portion (12, 14). The locking portion (20) and the abutment portion (18) are mutually connectable through the first and second tissue portions approximated, to keep them connected. The anastomotic device (10) is suitable for being connected to a guide means comprising at least one guide wire (A, B).

Abstract: A positioning device for deploying at least one locking portion (20) of an anastomotic device (10) for drawing together a first tissue portion (12) and a second tissue portion (14) to be connected by means of anastomosis is suitable for sliding along a guide means comprising at least one guide wire (A, B) and comprises an elongated structure (50). A head (52) of the positioning device is suitable to be interference-inserted on a distal end of the elongated structure (50). The head (52) comprises elastic tabs (54) extending from a proximal end of the head and at least one channel (56) suitable for receiving a guide wire. The head (52) comprises a distal end defining a thrust surface (58) for a locking portion (20) of the anastomotic device (10).

Abstract: A deployment system for introducing a surgical instrument (2) in a patients body by means of an elongate insertion device (8) which can be inserted in the patients body includes a coupling device (9, 15, 21) connectable with the surgical instrument (2) and shiftably connectable with the insertion device (8) such that the surgical instrument (2) can slide along the insertion device (8) in a guided manner, wherein the coupling device (9) includes one or more roller elements (10) configured to rollably contact the insertion device (8).

Abstract: A surgical instrument, such as a surgical stapling instrument (1), comprises a tissue manipulating portion (2) which is intended to be introduced in the body of a patient, a handle portion (3) with an actuating mechanism (7) adapted to generate actuating movements for the actuation of the tissue manipulating portion (2) and comprising at least a pair of rotary output members (33; 40) and an actuating transmission device (5, 5?; 6, 6?) connecting the actuating mechanism (7) of the handle portion (3) to the tissue manipulating portion (2) and comprising at least one pair of rotary rods (17, 17?; 19, 19?) for transmitting rotational actuating movements from the pair of rotary output members (33; 40) to the tissue manipulating portion (2). The actuating mechanism (7) comprises synchronization means (31, 32, 32?; 38, 20 39, 39?)which link the movements of the two rotary output members (33; 40) of the pair of rotary output members such that they counter-rotate at substantially the same speed.

Abstract: A device for manipulating body tissue comprises a base structure and at least one tubular member having a proximal end and an orientable distal end that defines a seat for supporting a surgical instrument, in which the tubular member is connected to the base structure. An actuation mechanism is suitable for orientating the distal end of the tubular member to take it into certain operative configurations. The actuation mechanism is also connected to the base structure. Means are also foreseen for the connection of the base structure to a distal end portion of an insertion tube of an endoscope or laparoscope, so that the actuation mechanism and the tubular member are arranged outside the insertion tube. The tubular member interacts with the actuation mechanism so that a movement of an actuation portion of the tubular member with respect to the base structure leads to the orientation of the orientable end.

Abstract: Traction means (14) for excising a tissue sample comprising a distal portion (14a), comprising at least one clip (20) suitable for being fixed to at least one portion (12) of tissue to be excised and a proximal portion (14b) suitable for being subjected to traction. Said at least one clip (20) is suitable for being connected to a distal end (22a) of a suture (22) to pull the tissue to be excised, said suture (22) extending between said distal end (22a) and a proximal end corresponding to the proximal portion of said traction means (14). Moreover, said at least one clip (20) is connected to a ring (24) formed at a distal end (24a) of said suture (22) to pull the tissue to be excised.

Abstract: In a rectally insertable surgical system (1), a sleeve device (2) having a proximal end and a distal end (16) is open at its proximal end and has a window area (20) longitudinally extending on one side of the sleeve device (2) up to its distal end region. A shield (4) is adapted to slide along the sleeve device (2) to at least partially close the window area (20). The sleeve device (2) including the shield (4) is insertable into an anus dilator ring (6).

Abstract: An anastomotic device, particularly a circular stapler (10), comprises a handle (12) and a stem (14). A channel suitable to receive a guide wire at least partially develops along the length of the stapler. The stem (14) is made of a flexible material, such as to facilitate reaching the site requiring anastomosis. The circular stapler (10) comprises an anvil (16) suitable to be introduced on the free end of the stem (14). The anvil (16) comprises a channel (22) suitable to receive a guide wire (66) and extending along the anvil, and a portion (20) suitable to act as a striker against the wall of one of the portions (A; B) of the tissues to be joined.

Abstract: A biopsy device may be used to obtain and store multiple tissue samples. The device permits the tissue samples to be stored in a sequenced fashion within a generally transparent tissue storage chamber disposed at a proximal end of the biopsy device. The tissue samples can be stored on flexible tissue sample strips arranged around the circumference of a rotating vacuum manifold disposed within the chamber.

Abstract: A laparoscopic surgical access device comprises a first frame and a second frame having relative axial positions. A flexible and resilient iris valve is connected to the first and second frames and has a closed position and an opened position based on the relative angular position of the first and second frames. A lock is connected to the first and second frames, the lock being selectively operative to prevent relative rotational movement in a first rotational direction. One embodiment uses a ratchet and pawl mechanism operable with a control ring. Another embodiment uses a ratchet and pawl mechanism operable with a button. Yet another embodiment uses a wedge track and ball mechanism.

Abstract: A laparoscopic surgical access device comprises a first frame and a second frame having relative axial positions. A flexible and resilient iris valve is connected to the first and second frames and has a closed position and an opened position based on the relative angular position of the first and second frames. A lock is connected to the first and second frames, the lock being selectively operative to prevent relative rotational movement in a first rotational direction. One embodiment uses a ratchet and pawl mechanism operable with a control ring. Another embodiment uses a ratchet and pawl mechanism operable with a button. Yet another embodiment uses a wedge track and ball mechanism.

Abstract: A biopsy device includes a cutter defining a cutter lumen and a tissue sample holder for collecting tissue samples. In one example, the tissue sample holder has a rotatable manifold that is configured to redirect fluid from one axial direction to an opposite axial direction. The tissue sample holder also has a plurality of tissue sample trays through which fluid may be communicated. The tissue sample trays define chambers that are each configured to separately hold tissue samples. The tissue sample trays are removable relative to the manifold. A cup is configured to cover the manifold and trays. A tissue sample holder rotation mechanism is operable to rotate the manifold to successively index each chamber of the tissue sample trays with the cutter lumen. A feature may prevent rotation of the manifold when one part of the biopsy device is separated from another part of the biopsy device.

Abstract: An anastomotic device, particularly a positioning device (24) extending along a longitudinal axis (30) comprises a first component, or proximal component (26) and a second component, or distal component (28). The proximal and distal components are suitable to lock an elastic ring (52) in a deformed configuration therebetween. The proximal component (26) has a substantially cylindrical outer structure with a cavity (32) for receiving a proximal end (52a) of the elastic ring (52). The distal component (28) comprises a head (42) and a stem (44) developing along the longitudinal axis (30). The head (42) has a cone or truncated-cone shape.

Abstract: A diagnostic device (10) for pathologies of tubular anatomical structures comprises a tubular elongated structure (12, 28) developing between a proximal end and a distal end and is suitable to be inserted in the tubular anatomical structure, means (22, 32) for locally dilating the walls of the tubular anatomical structure that are associated with the distal end of said elongated structure, said means for locally dilating being movable between a closed position for introducing the device and at least one open position for viewing and evaluating the pathology, and control means being associated with the proximal end of the elongated structure, said control means being operatively connected to said means for locally dilating, in order to move them between the closed position and the open position, and vice versa.

Abstract: A diagnostic device (10) for pathologies of tubular anatomical structures comprises a tubular elongated structure (12, 28) developing between a proximal end and a distal end and is adapted to be inserted in the tubular anatomical structure, means (22) for locally dilating the walls of the tubular anatomical structure being associated with the distal end of said elongated structure, said means for locally dilating being movable between a closed position for introducing the device and at least one open position for viewing and evaluating the pathology, and control means being associated with the proximal end of the elongated structure, said control means being operatively connected to said means for locally dilating, in order to move them between the closed position and the open position, and vice versa.

Abstract: An instrumentation for carrying out a gastrointestinal bypass comprises means for bringing close together a first tissue portion (12) of the intestine and second tissue portion (14) of the stomach by realising a first intestine loop (A), means for creating a gastroenteroanastomosis (16) between the two close tissue portions, for example a linear stapler, maintaining or restoring the continuity of the intestinal duct after the realisation of the gastroenteroanastomosis, means for bringing close together an additional first tissue portion (18) of the intestine, arranged distally with respect to the gastroenteroanastomosis (16) with reference to the natural flow of the food along the intestinal duct, and an additional second tissue portion (20) of the intestine arranged proximally with respect to the gastroenteroanastomosis (16) with reference to the natural flow of the food along the intestinal duct, realising a second loop (B) of the intestine, wherein said additional second tissue portion (20) of the intestin