Abstract: The present invention relates to novel compositions having anti-viral activity and in particular it relates to synergistic compositions active against Hepatitis C virus (HCV). The invention also relates to methods for retarding, reducing or otherwise inhibiting HCV growth and/or functional activity.

Abstract: Systems and methods for displaying content pre-delivered to a user device, playing back content pre-delivered to a user device, and/or pre-delivering content to a user device during concurrent content playback, are described. In some embodiments, the systems and methods include or interact with a mobile application that displays descriptions of content available for playback via the mobile application along with indicators that represent a state of delivery (e.g., a state of pre-delivery) for the content items.

Abstract: Systems and methods for displaying content pre-delivered to a user device, playing back content pre-delivered to a user device, and/or pre-delivering content to a user device during concurrent content playback, are described. In some embodiments, the systems and methods include or interact with a mobile application that displays descriptions of content available for playback via the mobile application along with indicators that represent a state of delivery (e.g., a state of pre-delivery) for the content items.

Abstract: Systems and methods for discovering content sources and/or delivering content to applications resident on mobile devices are described. In some embodiments, the systems and methods transmit information identifying one or more applications resident on a mobile device to a server, receive, from the server, information associated with content items available for retrieval from a content server and associated with the identified one or more applications, and cause the mobile device to retrieve at least one of the content items available for retrieval from the content server.

Abstract: The present invention relates to novel compositions having anti-viral activity and in particular it relates to synergistic compositions active against Hepatitis C virus (HCV). The invention also relates to methods for retarding, reducing or otherwise inhibiting HCV growth and/or functional activity.

Abstract: A handheld calculator with disable/re-enable capability. The calculator includes a keypad, a display screen, and circuitry internal to the calculator. The circuitry includes a microprocessor, a storage unit for storing data and programs for execution by the microprocessor to implement calculator functions. The storage unit has stored therein a disable/re-enable program that recognizes a first predetermined calculator event and in response thereto disables one or more programs, and that recognizes a second predetermined calculator event and in response thereto re-enables the disabled program. The invention allows Apps, programs and additional information that may be embedded within the Apps and programs in a calculator or other handheld calculating device to be rendered temporarily inaccessible within a relatively short period of time, and then to be restored to the calculator, again, in a relatively short period of time.

Abstract: A handheld calculator with disable/re-enable capability. The calculator includes a keypad, a display screen, and circuitry internal to the calculator. The circuitry includes a microprocessor, a storage unit for storing data and programs for execution by the microprocessor to implement calculator functions. The storage unit has stored therein a disable/re-enable program that recognizes a first predetermined calculator event and in response thereto disables one or more programs, and that recognizes a second predetermined calculator event and in response thereto re-enables the disabled program. The invention allows Apps, programs and additional information that may be embedded within the Apps and programs in a calculator or other handheld calculating device to be rendered temporarily inaccessible within a relatively short period of time, and then to be restored to the calculator, again, in a relatively short period of time.

Abstract: A two component reactive composition is described, each component, before they are mixed together, contains a filler having thin platelet structure, e.g. a nanoclay, and a further filler that interacts with the platelets. The individual components can have a filler loading that makes them flowable and therefore the components can readily be mixed together for ready dispensing. When the components are mixed thoroughly together, the resulting resin may have a viscosity higher than that of the individual components. The loading of the filler is preferably chosen so that the resulting blended resin is capable of being applied on to a vertical surface without experiencing significant slump. The viscosity of the mixed material can be up to 5 to 10 times or more than that of the individual components before mixing. The composition can be used in adhesives, modelling pastes, coatings, sealants, putties, mastics, stopping compounds, caulking materials, encapsulants and surface coatings.

Abstract: A two component reactive composition is described, each component, before they are mixed together, contains a filler having thin platelet structure, e.g. a nanoclay, and a further filler that interacts with the platelets. The individual components can have a filler loading that makes them flowable and therefore the components can readily be mixed together for ready dispensing. When the components are mixed thoroughly together, the resulting resin may have a viscosity higher than that of the individual components. The loading of the filler is preferably chosen so that the resulting blended resin is capable of being applied on to a vertical surface without experiencing significant slump. The viscosity of the mixed material can be up to 5 to 10 times or more than that of the individual components before mixing. The composition can be used in adhesives, modelling pastes, coatings, sealants, putties, mastics, stopping compounds, caulking materials, encapsulants and surface coatings.

Abstract: Neutral lipid formulations for nucleic acid delivery are provided according to the invention. The neutral lipid formulations include hydrophobically modified polynucleotides and fat mixtures. Methods of using the neutral lipid formulations are also provided.

Abstract: A two component reactive composition is described. Each component, before they are mixed together, contains a filler having thin platelet structure, e.g. a nanoclay, and a further filler that interacts with the platelets. The individual components can have a filler loading that makes them flowable and therefore the components can readily be mixed together for ready dispensing. When the components are mixed thoroughly together, the resulting resin may have a viscosity higher than that of the individual components. The loading of the filler is preferably chosen so that the resulting blended resin is capable of being applied on to a vertical surface without experiencing significant slump. The viscosity of the mixed material can be up to 5 to 10 times or more than that of the individual components before mixing. The composition can be used in adhesives, modelling pastes, coatings, sealants, putties, mastics, stopping compounds, caulking materials, encapsulants and surface coatings, e.g. paints.

Abstract: The present invention relates to novel compositions having anti-viral activity and in particular it relates to synergistic compositions active against Hepatitis C virus (HCV). The invention also relates to methods for retarding, reducing or otherwise inhibiting HCV growth and/or functional activity.

Abstract: Imidazole-substituted 4-anilino-3-cyanoquinolines are described, which selectively inhibit IFGR kinase activity and are useful for treating disorders associated with IGFR kinases.

Abstract: The present invention relates to a polypeptide monobody which includes a modified acid sequence and renders the polypeptide monobody able to bind selectively to ???3 integrin. Fusion proteins and conjugates which include the polypeptide monobody, as well as compositions containing the polypeptide monobody, fusion proteins, or conjugates are also disclosed. Uses thereof include: treating or preventing an ???3 integrin-mediated disease or disorder, inhibiting ???3 integrin activity, treating a cancerous or precancerous condition, imaging tissues using positron emission tomography or magnetic resonance imaging, assessing the metastatic characteristics of a tumor, and delivering DNA to a cell.

Abstract: The present invention relates to a polypeptide monobody which includes a modified acid sequence and renders the polypeptide monobody able to bind selectively to ?v?3 integrin. Fusion proteins and conjugates which include the polypeptide monobody, as well as compositions containing the polypeptide monobody, fusion proteins, or conjugates are also disclosed. Uses thereof include: treating or preventing an ?v?3 integrin-mediated disease or disorder, inhibiting ?v?3 integrin activity, treating a cancerous or precancerous condition, imaging tissues using positron emission tomography or magnetic resonance imaging, assessing the metastatic characteristics of a tumor, and delivering DNA to a cell.

Abstract: A two component reactive composition is described. Each component, before they are mixed together, contains a filler having thin platelet structure, e.g. a nanoclay, and a further filler that interacts with the platelets. The individual components can have a filler loading that makes them flowable and therefore the components can readily be mixed together for ready dispensing. When the components are mixed thoroughly together, the resulting resin may have a viscosity higher than that of the individual components. The loading of the filler is preferably chosen so that the resulting blended resin is capable of being applied on to a vertical surface without experiencing significant slump. The viscosity of the mixed material can be up to 5 to 10 times or more than that of the individual components before mixing. The composition can be used in adhesives, modelling pastes, coatings, sealants, putties, mastics, stopping compounds, caulking materials, encapsulants and surface coatings, e.g. paints.

Abstract: A handheld calculator with disable/re-enable capability. The calculator includes a keypad, a display screen, and circuitry internal to the calculator. The circuitry includes a microprocessor, a storage unit for storing data and programs for execution by the microprocessor to implement calculator functions. The storage unit has stored therein a disable/re-enable program that recognizes a first predetermined calculator event and in response thereto disables one or more programs, and that recognizes a second predetermined calculator event and in response thereto re-enables the disabled program. The invention allows Apps, programs and additional information that may be embedded within the Apps and programs in a calculator or other handheld calculating device to be rendered temporarily inaccessible within a relatively short period of time, and then to be restored to the calculator, again, in a relatively short period of time.

Abstract: A graphing calculator (10) having an X=Editor with inequalities. The calculator (10) is programmed to provide an X=Editor which displays one or more “X=” to allow input of a vertical line inequality. The X=Editor allows the user to input an inequality symbol and a constant for each X, allows the user to select or deselect each X, and a graph function to graph each selected X on the X=Editor display.

Abstract: A graphing calculator (10) or other computer based teaching tool that displays inequalities on a display screen. In contrast to prior art devices, the present invention provides displays of inequalities that are mathematically correct and consistent with non-electronic display of inequalities such as textbooks and black board representations to reinforce traditional teaching methods and help the student or user to readily see and understand the mathematical concepts involved. The display methods of the present invention are particularly useful for small, low-resolution displays that are typical of handheld computers and calculators.

Abstract: A computer spreadsheet application program on a graphing calculator or other computer that allows the user to lock and unlock individual or blocks of cells, and identifies those cells to the user. Similarly, other embodiments include the same user interface functionality in a ROM software application package that is executed on a graphing calculator or other handheld device.