Abstract: The present invention relates to 3D cell cultures, which contains hepatic cells and are infected by a pathogen, methods for preparing such cell cultures and uses thereof.

Abstract: A computer-implemented method is provided for comparing the security profile of a particular entity to peer entities. The method can include receiving, for a particular entity, (i) a value for at least one feature and (ii) a number of security records of one or more security risk types. The method can include determining peer entities based on the value of the features; obtaining, for each peer entity, a number of security records; and adjusting the number of peer security records based on the number of entity security records. The method can further include comparing, for one or more security risk types, the received number of security records for the particular entity to the respective adjusted number of security records for each peer entity; and comparing a security profile of the particular entity to security profiles of the population of peer entities based on the comparison for the security risk types.

Abstract: A computer-implemented method is provided for comparing the security profile of a particular entity to peer entities. The method can include receiving, for a particular entity, (i) a value for at least one feature and (ii) a number of security records of one or more security risk types. The method can include determining peer entities based on the value of the features; obtaining, for each peer entity, a number of security records; and adjusting the number of peer security records based on the number of entity security records. The method can further include comparing, for one or more security risk types, the received number of security records for the particular entity to the respective adjusted number of security records for each peer entity; and comparing a security profile of the particular entity to security profiles of the population of peer entities based on the comparison for the security risk types.

Abstract: A computer-implemented method is provided for comparing the security profile of a particular entity to peer entities. The method can include receiving, for a particular entity, (i) a value for at least one feature and (ii) a number of security records of one or more security risk types. The method can include determining peer entities based on the value of the features; obtaining, for each peer entity, a number of security records; and adjusting the number of peer security records based on the number of entity security records. The method can further include comparing, for one or more security risk types, the received number of security records for the particular entity to the respective adjusted number of security records for each peer entity; and comparing a security profile of the particular entity to security profiles of the population of peer entities based on the comparison for the security risk types.

Abstract: A detection system including a detection device and an assay device. The detection device includes a space for receiving an assay device, a drive arrangement engaging the assay device to rotate the assay device, a light source arranged to direct light towards the assay device, and a diffuser arranged to diffuse light from the light source. The diffuser is arranged between the light source and the space. The detection device includes a light receiver arranged to receive light from the light source that has passed through the assay device.

Abstract: The present application discloses a sintered ceramic material having high fracture toughness and bending strength, which is obtained from an yttria-stabilized Zirconia powder, the powder composition for obtaining said material, sintered ceramic pieces and manufacturing process thereof. One of the solutions of the present invention discloses a sintered ceramic material which is obtained from an yttria-stabilized zirconia powder, comprising between 1.8 and 2.1 mol % yttria, wherein the sintered ceramic material has a percentage of tetragonal phase greater than 90% at room temperature, a grain size between 0.1 to 0.25 ?m, the bending strength is between 1150-2100 MPa, and simultaneously a toughness greater than 10 MPa·m1/2. This material may be applied in different sintered ceramic pieces, including pieces for the automotive sector, for diverse machinery, ornamental applications such as timepieces or pieces for biomedical applications, among others.

Abstract: A rotary energy recovery device (11) wherein a multi-channel cylindrical rotor (15) revolves with its end faces (32) juxtaposed in sealing relationship with end surfaces (33) of a pair of flanking end covers (19, 21), and wherein inlet and outlet fluid passageways (27, 29) are provided in each end cover. Fluid may be directed into the rotor channels (16) and allowed to exit therefrom in an axial direction parallel to the axis of the rotor; however, rotor revolution is self-driven as a result of the interior design of the channels (16) which extend axially through the rotor and are shaped so that fluid flow therethrough creates a torque.

Abstract: Described embodiments provide devices, systems and methods for sequencing liquid flow in response to a driving force by entrapping and releasing gas between volumes of liquid in a controlled manner. In one particular form, a centrifugal “lab on a disk” device is provided to drive liquid flow and sequencing by virtue of the centrifugal force and in one particular form a radially inward bend conduit is used in connection with controllably trapping and releasing gas between liquid volumes.

Abstract: Described embodiments provide devices, systems and methods for sequencing liquid flow in response to a driving force by entrapping and releasing gas between volumes of liquid in a controlled manner. In one particular form, a centrifugal “lab on a disk” device is provided to drive liquid flow and sequencing by virtue of the centrifugal force and in one particular form a radially inward bend conduit is used in connection with controllably trapping and releasing gas between liquid volumes.

Abstract: Described embodiments provide devices, systems and methods for sequencing liquid flow in response to a driving force by entrapping and releasing gas between volumes of liquid in a controlled manner. In one particular form, a centrifugal “lab on a disk” device is provided to drive liquid flow and sequencing by virtue of the centrifugal force and in one particular form a radially inward bend conduit is used in connection with controllably trapping and releasing gas between liquid volumes.

Abstract: The present application discloses a sintered ceramic material having high fracture toughness and bending strength, which is obtained from an yttria-stabilized Zirconia powder, the powder composition for obtaining said material, sintered ceramic pieces and manufacturing process thereof. One of the solutions of the present invention discloses a sintered ceramic material which is obtained from an yttria-stabilized zirconia powder, comprising between 1.8 and 2.1 mol % yttria, wherein the sintered ceramic material has a percentage of tetragonal phase greater than 90% at room temperature, a grain size between 0.1 to 0.25 ?m, the bending strength is between 1150-2100 MPa, and simultaneously a toughness greater than 10 MPa·m1/2. This material may be applied in different sintered ceramic pieces, including pieces for the automotive sector, for diverse machinery, ornamental applications such as timepieces or pieces for biomedical applications, among others.

Abstract: A system for detecting the presence of an analyte in a moving substrate or sample handling device is disclosed, providing means (26,30) for integrated triggering of data acquisition with a detector means (28) and data acquisition with a detector means (28). In particular, a surface Plasmon resonance “lab on disk” reader system is disclosed.

Abstract: Described embodiments provide devices, systems and methods for sequencing liquid flow in response to a driving force by entrapping and releasing gas between volumes of liquid in a controlled manner. In one particular form, a centrifugal “lab on a disk” device is provided to drive liquid flow and sequencing by virtue of the centrifugal force and in one particular form a radially inward bend conduit is used in connection with controllably trapping and releasing gas between liquid volumes.

Abstract: A rotary energy recovery device (11) wherein a multi-channel cylindrical rotor (15) revolves with its end faces (32) juxtaposed in sealing relationship with end surfaces (33) of a pair of flanking end covers (19, 21), and wherein inlet and outlet fluid passageways (27, 29) are provided in each end cover. Fluid may be directed into the rotor channels (16) and allowed to exit therefrom in an axial direction parallel to the axis of the rotor; however, rotor revolution is self-driven as a result of the interior design of the channels (16) which extend axially through the rotor and are shaped so that fluid flow therethrough creates a torque.

Abstract: A system for detecting the presence of an analyte in a moving substrate or sample handling device is disclosed, providing means (26,30) for integrated triggering of data acquisition with a detector means (28) and data acquisition with a detector means (28). In particular, a surface Plasmon resonance “lab on disk” reader system is disclosed.

Abstract: A rotary pressure transfer device utilizes a multi-channel, generally cylindrical rotor (15) that revolves with its flat end faces juxtaposed with flat end surfaces of a pair of flanking end covers (19, 21) in which inlet and outlet passageways are provided. The design is such that there are only oblique ramps (65) in the passageways on the high pressure side which create directional flow of liquid to cause rotor revolution in the desired direction. Passageways (27a, 27b) on the low pressure side may be shaped so that there is essentially axial or longitudinal flow entry and discharge of liquid between the channels and the passageways, or passageways (71) may be constructed to create directional flow that slightly retards rotor revolution in such desired direction.