Patents by Inventor Mikael O. Trollsas

Mikael O. Trollsas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Implantable drug delivery devices having alternating hydrophilic and amphiphillic polymer layers
    Patent number: 8343529
    Abstract: An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: January 1, 2013
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F. A. Hossainy, Mikael O. Trollsas, Lothar W. Kleiner
  • Coatings of acrylamide-based copolymers
    Patent number: 8333984
    Abstract: An implantable device including conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: December 18, 2012
    Assignee: Abbott Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Thierry Glauser, Mikael O. Trollsas
  • Poly(ester-amide) and poly(amide) coatings for implantable medical devices for controlled release of a protein or peptide and a hydrophobic drug
    Patent number: 8323676
    Abstract: This invention is generally related to coatings for implantable medical devices, such as drug delivery vascular stents. The coating includes a drug reservoir layer above the outer surface of the device body, the drug reservoir layer with a peptide or protein, a hydrophobic drug, and a polymer with a weight average molecular weight between about 10,000 to about 150,000 Daltons. A preferred polymer is a poly(ester amide) polymer.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: December 4, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Florencia Lim, Mikael O. Trollsas, Xinmin Xu, Bozena Zofia Maslanka
  • SOLUBLE COATING COMPRISING POLYELECTROLYTE WITH HYDROPHOBIC COUNTERIONS
    Publication number: 20120276185
    Abstract: The present invention provides an implantable device having a biosoluble coating comprising a polyelectrolyte and a counterion and the methods of making and using the same.
    Type: Application
    Filed: July 9, 2012
    Publication date: November 1, 2012
    Inventors: Syed F.A. Hossainy, Mikael O. Trollsas, Lothar W. Kleiner
  • Implantable Drug Delivery Devices Having Alternating Hydrophilic And Amphiphilic Polymer Layers
    Publication number: 20120225303
    Abstract: An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed.
    Type: Application
    Filed: May 17, 2012
    Publication date: September 6, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F.A. Hossainy, Mikael O. Trollsas, Lothar W. Kleiner
  • Implantable drug delivery devices having alternating hydrophilic and amphiphilic polymer layers
    Patent number: 8202529
    Abstract: An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: June 19, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F. A. Hossainy, Mikael O. Trollsas, Lothar W. Kleiner
  • POLY(AMIDE) AND POLY(ESTER-AMIDE) POLYMERS AND DRUG DELIVERY PARTICLES AND COATINGS CONTAINING SAME
    Publication number: 20110311596
    Abstract: The current invention relates to poly(amide) and poly(ester-amide) polymers, coatings including the polymers, and narrow polydispersity drug delivery particles including the polymers.
    Type: Application
    Filed: August 30, 2011
    Publication date: December 22, 2011
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Michael Huy Ngo, Mikael O. Trollsas, Thierry Glauser, Jinping Wan, Bozena Zofia Maslanka
  • COATINGS OF ACRYLAMIDE-BASED COPOLYMERS
    Publication number: 20110293675
    Abstract: An implantable device including conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided.
    Type: Application
    Filed: August 9, 2011
    Publication date: December 1, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Thierry Glauser, Mikael O. Trollsas
  • Implantable Medical Device With Poly(Vinylidene Fluoride-Co-Hexafluoropropylene)/Zotarolimus Drug Layer
    Publication number: 20110229548
    Abstract: This invention relates to an implantable medical device for and method of treating a vascular disease where the device is preferably a stent comprising a drug reservoir layer comprising poly(vinylidene fluoride-co-hexafluoropropylene) and zotarolimus.
    Type: Application
    Filed: March 18, 2010
    Publication date: September 22, 2011
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Florencia Lim, Shawn Chin Quee, Mikael O. Trollsas
  • Coatings of acrylamide-based copolymers
    Patent number: 8017141
    Abstract: An implantable device including conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: September 13, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Thierry Glauser, Mikael O. Trollsas
  • Hygroscopic coating on a balloon device
    Publication number: 20110129514
    Abstract: The present invention provides a hygroscopic coating on a balloon for an implantable device and methods of making and using the same.
    Type: Application
    Filed: September 6, 2007
    Publication date: June 2, 2011
    Inventors: Syed F.A. Hossainy, Mikael O. Trollsas, Keith Cromack
  • Thioester-ester-amide copolymers
    Patent number: 7927621
    Abstract: A poly(thioester ester amide) copolymer and method of making and using the same are disclosed.
    Type: Grant
    Filed: June 25, 2007
    Date of Patent: April 19, 2011
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Mikael O. Trollsas, Nam D. Pham, Michael H. Ngo, Bozena Zofia Maslanka
  • Implantable medical devices comprising semi-crystalline poly(ester-amide)
    Patent number: 7771739
    Abstract: The current invention relates to an implantable medical device made of semi-crystalline poly(ester amide) (PEA) polymer.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: August 10, 2010
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Mikael O. Trollsas, David C. Gale, Yunbing Wang
  • Biodegradable Poly(Ester-Amide) And Poly(Amide) Coatings For Implantable Medical Devices With Enhanced Bioabsorption Times
    Publication number: 20100047319
    Abstract: This invention is generally related to coating layers for implantable medical devices, such as drug delivery vascular stents, and methods of fabricating coated implantable medical devices. Specifically various embodiments of the present invention include methods of fabricating and modulating of coating layers to enhance bioabsorption. The coating layers include poly(ester-amide) and/or poly(amide) polymers.
    Type: Application
    Filed: August 21, 2008
    Publication date: February 25, 2010
    Inventors: Michael Huy Ngo, Syed F. A. Hossainy, Florencia Lim, Mikael O. Trollsas
  • Poly(Ester-Amide) And Poly(Amide) Coatings For Implantable Medical Devices For Controlled Release Of A Protein Or Peptide And A Hydrophobic Drug
    Publication number: 20090324672
    Abstract: This invention is generally related to coatings for implantable medical devices, such as drug delivery vascular stents. The coating includes a drug reservoir layer above the outer surface of the device body, the drug reservoir layer with a peptide or protein, a hydrophobic drug, and a polymer with a weight average molecular weight between about 10,000 to about 150,000 Daltons. A preferred polymer is a poly(ester amide) polymer.
    Type: Application
    Filed: June 30, 2008
    Publication date: December 31, 2009
    Inventors: Florencia Lim, Mikael O. Trollsas, Xinmin Xu, Bozena Zofia Maslanka
  • Poly(Amide) And Poly(Ester-Amide) Polymers And Drug Delivery Particles And Coatings Containing Same
    Publication number: 20090324671
    Abstract: The current invention relates to poly(amide) and poly(ester-amide) polymers, coatings including the polymers, and narrow polydispersity drug delivery particles including the polymers.
    Type: Application
    Filed: June 30, 2008
    Publication date: December 31, 2009
    Inventors: Michael Huy Ngo, Mikael O. Trollsas, Thierry Glauser, Jinping Wan, Bozena Zofia Maslanka
  • BIOSOLUBLE COATING COMPRISING ANTI-PROLIFERATIVE AND ANTI-INFLAMMATORY AGENT COMBINATION FOR TREATMENT OF VASCULAR DISORDERS
    Publication number: 20090297578
    Abstract: Drug-delivery systems such as drug-delivery stents having an anti-proliferative agent such as everolimus and an anti-flammatory agent such as clobetasol are provided. Also disclosed are methods of treating a vascular impairment such as restenosis or vulnerable plaque.
    Type: Application
    Filed: June 3, 2008
    Publication date: December 3, 2009
    Inventors: MIKAEL O. TROLLSAS, Michael H. Ngo, Florencia Lim, Syed F.A. Hossainy, Bozena Zofia Maslanka
  • Implantable Drug Delivery Devices Having Alternating Hyrdrophilic And Amphiphilic Polymer Layers
    Publication number: 20090297575
    Abstract: An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed.
    Type: Application
    Filed: May 30, 2008
    Publication date: December 3, 2009
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F.A. Hossainy, Mikael O. Trollsas, Lothar W. Kleiner
  • BIOSOLUBLE COATING WITH LINEAR OVER TIME MASS LOSS
    Publication number: 20090297584
    Abstract: Implantable devices such as stents having a biosoluble coating with linear over time mass loss are provided. Also disclosed are methods of making and using the implantable device.
    Type: Application
    Filed: August 20, 2008
    Publication date: December 3, 2009
    Inventors: FLORENCIA LIM, Michael H. Ngo, Mikael O. Trollsas
  • IMPLANTABLE MEDICAL DEVICES AND COATINGS THEREFOR COMPRISING BLOCK COPOLYMERS OF POLY(ETHYLENE GLYCOL) AND A POLY(LACTIDE-GLYCOLIDE)
    Publication number: 20090285873
    Abstract: The present invention provides a block copolymer for a coating on an implantable device for controlling release of drug and methods of making and using the same.
    Type: Application
    Filed: June 15, 2009
    Publication date: November 19, 2009
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: FLORENCIA LIM, Mikael O. Trollsas, Michael H. Ngo, Jie Hu, Syed F. A. Hossainy, David J. Sherman