Abstract: A method for performing online convex optimization is provided. The method includes receiving, from two or more worker nodes, a local decision vector and local data corresponding to each of the two or more worker nodes. The method includes performing a multi-step gradient descent based on the local decision vector and the local data received from the two or more worker nodes. Performing the multi-step gradient descent includes determining a global decision vector and corresponding global information. The method includes sending, to each of the two or more worker nodes, the global decision vector and corresponding global information.

Abstract: A system selecting a process key factor in a commercial chemical process, includes: a data extraction unit that extracts tag data in units of a set period; an outlier discrimination unit that discriminates and aggregates outliers by tag by using an outlier extraction reference master; an outlier processing unit that generates an input mart draft excluding the outliers; a derived variable generation unit that generates derived variables for each tag, and generates an advanced input mart having the derived variable added thereto; a yield calculation unit that backs up the result of calculation of a yield by realizing a target value via exclusion and correction of the outliers; and a key factor extraction unit that extracts a yield key factor by calculating importance of each tag, and backs up importance data for each tag.

Abstract: Disclosed herein are an antimicrobial reinforced floor and a method for preparing the same. In the method, a substrate and an impregnated paper impregnated with an inorganic antimicrobial agent and an organic antimicrobial agent are subjected to hot press forming to produce the antimicrobial reinforced floor.

Abstract: Copolymers comprising recurring units of a phenyl glycidyl ether and alkylene oxides are disclosed. Some of the copolymers comprise a di- or polyfunctional nucleophilic initiator and recurring units of the phenyl glycidyl ether and an alkylene oxide. The di- or polyfunctional nucleophilic initiator is an alcohol, phenol, amine, thiol, thiophenol, sulfinic acid, or deprotonated species thereof. Other copolymers comprise a monofunctional nucleophilic initiator selected from thiols, thiophenols, aralkylated phenols, sulfinic acids, secondary amines, C10-C20 terpene alcohols, and deprotonated species thereof. Pigments dispersions comprising the copolymers are also disclosed. The copolymers meet the growing needs of the industry with their ease of manufacture, diverse structures, and desirable performance attributes for dispersing a wide range of organic and inorganic pigments. Agricultural applications for the copolymers are also disclosed.

Abstract: A system for predicting process changes by using key factors in a commercial chemical process, includes: a key factor extraction and individual tag importance backup unit that extracts yield key factors by calculating the importance of each tag, and backs up importance data for each tag; and a yield prediction model training and yield prediction performing unit that performs yield prediction model training by using the importance of each tag accumulated in the key factor extraction and individual tag importance backup unit, and performs yield prediction so as to output a yield prediction result, evaluates performance, and selects an optimal prediction model.

Abstract: Disclosed herein are modified Clostridial Botulinum neurotoxin (BoNT) polypeptides with a modified receptor binding domain of Clostridial Botulinum serotype A1 or A2. Modifications include substitution amino acid mutations. Isolated modified receptor binding domains, chimeric molecules, pharmaceutical compositions, and methods of using the same are also disclosed.

Abstract: Compositions of self-crosslinking composite binders for silicon-based electrodes, associated processes of forming silicon-based electrodes using the composite binders, as well as batteries utilizing the silicon-based electrodes formed using the composite binders are disclosed herein. In certain examples, the composite binder can include a first component configured to provide structural integrity in a silicon-based electrode and a second component configured to form a mesh-like structural network with the first component to provide flexibility of the silicon-based electrode and adhesiveness toward a current collector. The flexible mesh-like structural network is formed via gradient hydrogen bonds between chains of the first component and chains of the second components.

Abstract: The disclosure provides fusion proteins comprising a pleckstrin homology (PH) domain and a variant of Botulinum neurotoxin E (BoNT E) protease that cleaves certain non-canonical protein targets (e.g., PTEN). Fusion proteins described in the disclosure are useful for cleaving target proteins found in a cell, that is, in an intracellular environment. Aspects of the disclosure provide methods for inhibiting PTEN amount, activity, or function in a cell or subject, the methods comprising administering to a call or subject a fusion protein described herein.

Abstract: Embodiments of a method and network node for managing wireless devices (WDs) in a network are disclosed. In some embodiments, the method comprises grouping the plurality of WDs into clusters based at least in part on correlations between channels of the WDs. The method also includes determining beam forming weights for each cluster, the grouping into clusters and the determining of beam forming weights being performed to minimize a total transmit power to the plurality of WDs.

Abstract: A stator lamination includes a middle part, an annular yoke, and a plurality of stator teeth. The middle part includes a central hole. The plurality of stator teeth extend from the inner side of the annular yoke and are evenly distributed. A wire slot is formed between every two adjacent stator teeth, whereby the annular yoke includes a plurality of wire slots. Each of the plurality of stator teeth includes a tooth root and a pole shoe disposed at one end of the tooth root. The stator lamination has an outer diameter ranging from 61.75 mm to 68.25 mm, and the central hole has a diameter ranging from 31.6 mm to 35 mm. The plurality of wire slots are evenly distributed around an edge of a circle, and the bottom part of each wire slot is tangent to the circle.

Abstract: Disclosed herein are means for the detection and characterization of neurotoxins such as botulinum neurotoxin (BoNT) or tetanus neurotoxin. The present disclosure provides methods for determining potency and activity of neurotoxins in vitro and in vivo. Also disclosed are polypeptides comprising N- and C-terminal fragments of a reporter protein that are split by a linker comprising a neurotoxin cleavage site. Cleavage of the linker by a neurotoxin decreases reporter protein activity, thereby indicating activity of the neurotoxin. Compositions and kits comprising the disclosed polypeptides, nucleic acids comprising nucleotide sequences encoding such polypeptides, and cells expressing such polypeptides are also disclosed.

Abstract: Sulfate and sulfonate derivatives of unsaturated fatty alcohols, processes for making them, and methods of using them are disclosed. In one aspect, a monounsaturated fatty alcohol composition is made by reducing a metathesis-derived monounsaturated alkyl ester. The fatty alcohol composition is then converted to a sulfate or sulfonate derivative by one or more of alkoxylation, sulfation, sulfonation, and sulfitation. Of particular interest are the sulfate and ether sulfate derivatives. Microscopy studies indicate that the unsaturated sodium sulfates in particular have a lamellar phase that should enable formulation at high actives levels. Sulfate compositions comprising 40 to 60 wt. % of a monounsaturated fatty primary alcohol sulfate and 40 to 60 wt. % of a secondary hydroxyalkyl primary alcohol sulfate are also disclosed.

Abstract: A method and network node configured to perform wireless network virtualization to allocate resources of an infrastructure provider (InP) among a plurality of service providers (SPs) are provided. According to one aspect, a method in a network node includes, in each of a plurality of successive time slots in a time interval, T: receiving precoding feedback information from each SP, allocating a virtual transmit power to each cell served by an SP based at least in part on the received precoding feedback information and determining a precoding matrix for each SP. The method also includes minimizing a loss function based at least in part on the received precoding feedback information received in multiple previous time slots.

Abstract: The present disclosure relates to a passive fiber optic cabinet and a system for detecting a state of a door of a passive fiber optic cabinet. A passive fiber optic cabinet is provided, comprising: a housing; a door coupled to the housing and configured to be switchable between an open state and a closed state; a switch sensor module including a detection fiber Bragg grating (FBG) sensor and a stress applying mechanism corresponding to the detection FBG sensor, the stress applying mechanism configured to apply a stress o the detection FBG sensor, one of the detection FBG sensor and the stress applying mechanism being positioned at the door, and the other of the detection FBG sensor and the stress applying mechanism being positioned at the housing.

Abstract: A method and network node for distributed coordinated downlink precoding for multi-cell multiple input multiple output (MIMO) wireless network virtualization are disclosed. According to one aspect, a network node is configured to, in each of a plurality of successive transmission time periods: transmit to each of a plurality of SPs a corresponding set of channel information; receive from each of the plurality of SPs a service demand and a normalized precoding matrix, the normalized precoding matrix being determined by the corresponding SP based on the corresponding set of channel information; allocate a virtual transmit power to each of the plurality of SPs based at least in part on the received service demands and normalized precoding matrices; and determine a downlink precoding matrix to transmit messages to WDs, the downlink precoder matrix being based at least in part on the received service demands and normalized precoding matrices.

Abstract: Deimmunized botulinum toxin light chain (e.g., botulinum toxin serotype A light chains (BoNT/A-LC)) or fragments thereof are provided. Methods for treating or preventing diseases or disorders comprising administering to a subject a deimmunized botulinum toxin light chain (e.g., BoNT/A-LC) are provided.

Abstract: A method and network node for online coordinated multi-cell precoding are provided. According to one aspect, a method includes receiving from each of the plurality of service providers a virtual precoder matrix determined by the corresponding service provider. The method also includes determining a precoder matrix by minimizing a precoding deviation from a virtualization demand of the network subject to at least one power constraint, the virtualization demand being based at least in part on a product of a channel state matrix and a virtual precoder matrix. The method further includes applying the determined precoder matrix to signals applied to a plurality of antennas to achieve a sum of throughputs for the plurality of service providers that is greater than a sum of throughputs for the plurality of service providers achievable when the virtual precoder matrices are applied to the signals.

Abstract: Disclosed herein are means for the detection and characterization of neurotoxins such as botulinum neurotoxin (BoNT) or tetanus neurotoxin. The present disclosure provides methods for determining potency and activity of neurotoxins in vitro and in vivo. Also disclosed are polypeptides comprising N- and C-terminal fragments of a reporter protein that are split by a linker comprising a neurotoxin cleavage site. Cleavage of the linker by a neurotoxin decreases reporter protein activity, thereby indicating activity of the neurotoxin. Compositions and kits comprising the disclosed polypeptides, nucleic acids comprising nucleotide sequences encoding such polypeptides, and cells expressing such polypeptides are also disclosed.

Abstract: In accordance with some aspects of the disclosure, a modular telecommunications patch panel system is shown and described. The panel can include a mounting frame extending between a first end and a second end, the mounting frame defining a plurality of apertures for receiving telecommunications components, a first mounting ear forming a snap-fit connection with the mounting frame first end, in a first orientation, and a second mounting ear, identical to the first mounting ear, forming a snap-fit connection with the mounting frame second end, in a second orientation.

Abstract: A splice cassette (100) includes a housing (114) which defines a first and a second interiors (132,134) facing in opposite directions. A first splice region (150) is disposed in the first interior (132) and a second splice region (152) is disposed in the second interior (134). A splice holder (180,185) can be mounted removably at one or more of the splice regions (150,152).