Patents by Inventor Min Fu
Min Fu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12630876Abstract: The present invention provides a mass spectrometry-based method and a kit for genotyping of platelet and neutrophil antigens and glycoproteins, which are used for genotyping of platelet-specific antigens, platelet CD36 glycoproteins and neutrophil antigens; by designing an optimal primer combination, problems such as homologous sequences and rich GC are overcome, moreover, by improving amplification reaction conditions and using nucleic acid mass spectrometry as a platform, 35 platelet-specific antigen polymorphic sites, 10 CD36 polymorphic sites and 8 neutrophil antigen polymorphic sites can be simultaneously detected in 2 reactions. The present invention has the characteristics of high specificity and sensitivity, and fast and high throughput, and can be used in clinic, scientific research, platelet donor routine screening, etc.Type: GrantFiled: January 19, 2023Date of Patent: May 19, 2026Assignee: SHANGHAI BLOOD CENTERInventors: Luyi Ye, Huijun Zhu, Ruishu Li, Min Fu, Ping Lu, Ziyan Zhu
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Publication number: 20260028443Abstract: Provided are a polymer medicament for treating hyperkalemia, and a preparation method thereof. Specifically, a polymer is provided, and the polymer includes repeating units obtained by polymerizing a monomer and a crosslinking agent. A molar ratio of the monomer to the crosslinking reagent ranges from 1:0.02 to 1:0.20. The monomer includes an acidic group and a pKa-reducing group next to the acidic group. The acidic group is selected from the group consisting of sulfonic acid group (—SO3?), sulfuric acid group (—OSO3?), carboxylic group (—CO2?), phosphonic acid group (—OPO32?), phosphate group (—OPO32?), and sulfamic acid group (—NHSO3?). The pKa-reducing group is selected from the group consisting of nitro, cyano, carbonyl, trifluoromethyl, and halogen atoms. The crosslinking agent has three or four reaction sites. The polymer can be used to treat hyperkalemia.Type: ApplicationFiled: September 29, 2025Publication date: January 29, 2026Inventors: Min FU, Huiling TANG, Tongtong LI, Minglong HU, Kang BIE, Ying LIANG, Jian CUI, Faming ZHANG
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Patent number: 12526320Abstract: Provided are network security defense method and network security defense system. The method includes: processing data multiple times using a preset processing strategy, where the processing strategy includes a first strategy and a second strategy, the first strategy is used for eliminating an influence of generalized disturbance on the second strategy, the second strategy after being eliminated the influence is applied to the data for calculation, storage and communication of the data, the first strategy includes an encoding strategy, a decoding strategy and a memory elimination strategy, and the generalized disturbance includes random disturbance and/or non-random disturbance; triggering a feedback control strategy based on a decoding result of the multiple processing results; and adjusting the first strategy according to the feedback control strategy.Type: GrantFiled: June 7, 2021Date of Patent: January 13, 2026Assignees: China National Digital Switching System Engineering & Technological R&D Center, Zhuhai Comleader Information Science & Technology Corp., Ltd.Inventors: Jiangxing Wu, Lei He, Quan Ren, Jun Zhou, Min Fu, Weili Zhang, Ruihao Ding, Yiwei Guo, Jinsuo Zhou
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Publication number: 20260005308Abstract: A lithium ion battery electrolyte with improved wettability and a lithium ion battery is disclosed. The electrolyte includes 10% to 17% of lithium salt, 1.8% to 3.7% of film-forming additive, 0.5% to 10% of wetting additive with the balance being solvent. The wetting additive is fluorobenzene and a silanyl fluorobenzene compound, with a mass fraction of fluorobenzene in the electrolyte being at least 3% and a mass fraction of the silanyl fluorobenzene compound being not less than 1%. Two types of silanyl fluorobenzene compounds provided are mainly composed of silanyl groups which absorb HF and reduce surface tension and fluorophenyl groups which reduce surface tension. By using the silanyl fluorobenzene compounds together with fluorobenzene, a problem of performance deviation caused by generation of HF by fluorobenzene at high temperature can be solved, and wettability of the electrolyte can also be provided.Type: ApplicationFiled: August 8, 2025Publication date: January 1, 2026Inventors: Min FU, Lanlan SHI, Min SU
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Patent number: 12416119Abstract: A rubber particle-doped composite chip seal and a construction method thereof. The rubber particle-doped composite chip seal includes a coarse aggregate in a lower layer, a fine aggregate in an upper layer, and an SBS-modified emulsified asphalt binding and encapsulating the coarse aggregate and the fine aggregate into a whole, wherein the coarse aggregate is a gravel having a particle size of 4.75 mm to 7.1 mm, the fine aggregate is rubber particles having a particle size of 1.18 mm to 4.75 mm after pre-treatment, and the fine aggregate has a doping amount of 30% to 45% of a volume of all aggregates.Type: GrantFiled: March 8, 2024Date of Patent: September 16, 2025Assignee: CHANGSHA UNIVERSITY OF SCIENCE & TECHNOLOGYInventors: Jianguo Wei, Yuming Zhou, Hao Yue, Anmin Zou, Ping Li, Haolong Ju, Qiucai Nan, Min Fu
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Publication number: 20250286622Abstract: Disclosed is an optical fiber distributed wireless signal coverage system based on a radio over fiber (ROF) technology, including a signal access intelligent unit, configured to perform radio frequency signal magnitude conditioning and then radio frequency amplification on a first wireless signal to obtain a first downlink electrical signal and combine the first downlink electrical signal, an OOK modulating signal, and a first radio frequency signal together and convert the same into a downlink laser signal, and output the signal to a first optical fiber interface; and further configured to convert a resultant uplink laser signal into an uplink electrical signal and perform radio frequency amplification and radio frequency signal magnitude conditioning on the uplink electrical signal to output the signal from a radio frequency interface; an optical fiber splitter, configured to divide the downlink laser signal into downlink laser sub-signals; and at least one multi-standard remote radio unit.Type: ApplicationFiled: February 26, 2025Publication date: September 11, 2025Inventors: MIN FU, GUOPENG LUO, QINGHUA LIAO, JIANGUO CHEN, XIAOQIN LI, CHIGUANG HE
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Publication number: 20250145829Abstract: Disclosed are a rubber particle-doped composite chip seal and a construction method thereof. The chip seal includes: a coarse aggregate in a lower layer, a fine aggregate in an upper layer, and an SBS-modified emulsified asphalt binding and encapsulating the coarse aggregate and the fine aggregate into a whole, wherein the coarse aggregate is a gravel having a particle size of 4.75 mm to 7.1 mm, the fine aggregate is rubber particles having a particle size of 1.18 mm to 4.75 mm after pre-treatment, and the fine aggregate has a doping amount of 30% to 45% of a volume of all aggregates.Type: ApplicationFiled: March 8, 2024Publication date: May 8, 2025Inventors: Jianguo WEI, Yuming ZHOU, Hao YUE, Anmin ZOU, Ping LI, Haolong JU, Qiucai NAN, Min FU
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Patent number: 12267303Abstract: A structural encoding unit and an error correction decoding unit are divided. The structure encoding unit is divided into input branch processor and an input proxy processor; and the error correction decoding unit is divided into an output routing processor, an output proxy processor, an adjudication branch processor, an adjudication proxy processor and a voting processor. The input branch processor is used for duplicating and distributing messages, the arbitration branch processor is used for duplicating and distributing data, the voting processor is used for performing voting, and the output routing processor is used for selecting an output result from processing results of the output proxy processor according to a voting result of the voting processor.Type: GrantFiled: June 7, 2021Date of Patent: April 1, 2025Assignees: CHINA NATIONAL DIGITAL SWITCHING SYSTEM ENGINEERING & TECHNOLOGICAL R&D CENTER, PURPLE MOUNTAIN LABORATORIESInventors: Lei He, Jiangxing Wu, Qinrang Liu, Ke Song, Shuai Wei, Jianliang Shen, Libo Tan, Yu Li, Quan Ren, Jun Zhou, Min Fu, Weili Zhang, Ruihao Ding, Yiwei Guo
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Publication number: 20240139234Abstract: Provided herein is a potassium-binding polymer prepared by polymerization reaction of a monomer and a crosslinking agent, wherein the monomer is the compound of formula (V), the crosslinking agent is the compound of formula (VI), and/or the compound of formula (VII), wherein the variables are as defined in the specification; to the use thereof for treating or preventing hyperkalemia.Type: ApplicationFiled: November 4, 2021Publication date: May 2, 2024Applicant: WATERSTONE PHARMACEUTICALS (WUHAN) CO., LTD.Inventors: Min FU, Minglong HU, Tongtong LI, Ying LIANG, Xiaolong WANG, Yao YU, Faming ZHANG
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Publication number: 20230235390Abstract: The present invention provides a mass spectrometry-based method and a kit for genotyping of platelet and neutrophil antigens and glycoproteins, which are used for genotyping of platelet-specific antigens, platelet CD36 glycoproteins and neutrophil antigens; by designing an optimal primer combination, problems such as homologous sequences and rich GC are overcome, moreover, by improving amplification reaction conditions and using nucleic acid mass spectrometry as a platform, 35 platelet-specific antigen polymorphic sites, 10 CD36 polymorphic sites and 8 neutrophil antigen polymorphic sites can be simultaneously detected in 2 reactions. The present invention has the characteristics of high specificity and sensitivity, and fast and high throughput, and can be used in clinic, scientific research, platelet donor routine screening, etc.Type: ApplicationFiled: January 19, 2023Publication date: July 27, 2023Inventors: Luyi YE, Huijun ZHU, Ruishu LI, Min FU, Ping LU, Ziyan ZHU
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Patent number: 11705758Abstract: A wireless power transmitting terminal and control method are disclosed. The wireless power transmitting terminal including an inverter circuit, a resonance circuit and a controller, wherein in a frequency detection state, an alternating current of the inverter circuit is controlled to switch between different candidate frequencies, so as to determine a resonance frequency and a maximum peak value of an electrical parameter of the alternating current at the resonance frequency, and determine an operating state of the power transmitting terminal according to the change of the maximum peak value. Therefore, the wireless power transmitting terminal can dynamically adjust in real time a preset operating state thereof, thereby improving the device adaptability, and avoiding the damage of the device to be charged.Type: GrantFiled: September 28, 2021Date of Patent: July 18, 2023Assignee: Ningbo Weie Electronics Technology Ltd.Inventors: Feng Yu, Lizhi Xu, Weiyi Feng, Min Fu
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Publication number: 20230224333Abstract: Provided are network security defense method and network security defense system. The method includes: processing data multiple times using a preset processing strategy, where the processing strategy includes a first strategy and a second strategy, the first strategy is used for eliminating an influence of generalized disturbance on the second strategy, the second strategy after being eliminated the influence is applied to the data for calculation, storage and communication of the data, the first strategy includes an encoding strategy, a decoding strategy and a memory elimination strategy, and the generalized disturbance includes random disturbance and/or non-random disturbance; triggering a feedback control strategy based on a decoding result of the multiple processing results; and adjusting the first strategy according to the feedback control strategy.Type: ApplicationFiled: June 7, 2021Publication date: July 13, 2023Inventors: Jiangxing WU, Lei HE, Quan REN, Jun ZHOU, Min FU, Weili ZHANG, Ruihao DING, Yiwei GUO, Jinsuo ZHOU
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Publication number: 20230167404Abstract: A urine-derived mesenchymal stem cell mitochondria as well as a transplantation method and use thereof. The urine-derived mesenchymal stem cell mitochondrion is extracted from urine to be used for improving the quality of oocytes. The transplantation method comprises: jointly injecting sperms and the urine-derived mesenchymal stem cell mitochondria into mature oocytes for blastaea culture during the intracytoplasmic sperm microinjection.Type: ApplicationFiled: January 13, 2022Publication date: June 1, 2023Inventors: Huan Shen, Zhixin Jiang, Cheng Shi, Yanbin Wang, Xi Chen, Hongjing Han, Min Fu, Jia Fei
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Publication number: 20230102317Abstract: Provided are a polymer medicament for treating hyperkalemia, and a preparation method thereof. Specifically, a polymer is provided, and the polymer includes repeating units obtained by polymerizing a monomer and a crosslinking agent. A molar ratio of the monomer to the crosslinking reagent ranges from 1:0.02 to 1:0.20. The monomer includes an acidic group and a pKa-reducing group next to the acidic group. The acidic group is selected from the group consisting of sulfonic acid group (—SO3—), sulfuric acid group (—OSO3—), carboxylic group (—CO2—), phosphonic acid group (—OPO32—), phosphate group (—OPO32—), and sulfamic acid group (—NHSO3—). The pKa-reducing group is selected from the group consisting of nitro, cyano, carbonyl, trifluoromethyl, and halogen atoms. The crosslinking agent has three or four reaction sites. The polymer can be used to treat hyperkalemia.Type: ApplicationFiled: March 16, 2022Publication date: March 30, 2023Inventors: Min FU, Huiling TANG, Tongtong LI, Minglong HU, Kang BIE, Ying LIANG, Jian CUI, Faming ZHANG
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Publication number: 20230039521Abstract: Provided is an input/output system applied to a network security defense system. A structural encoding unit and an error correction decoding unit are divided. The structure encoding unit is divided into input branch module and an input proxy module; and the error correction decoding unit is divided into an output routing module, an output proxy module, an adjudication branch module, an adjudication proxy module and a voting module. The input branch module is used for duplicating and distributing messages, the arbitration branch module is used for duplicating and distributing data, the voting module is used for performing voting, and the output routing module is used for selecting an output result from processing results of the output proxy module according to a voting result of the voting module.Type: ApplicationFiled: June 7, 2021Publication date: February 9, 2023Inventors: Lei HE, Jiangxing WU, Qinrang LIU, Ke SONG, Shuai WEI, Jianliang SHEN, Libo TAN, Yu LI, Quan REN, Jun ZHOU, Min FU, Weili ZHANG, Ruihao DING, Yiwei GUO
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Publication number: 20230033253Abstract: Provided are a security defense method and apparatus applied to a network security defense system. The method includes: using memoryless technology in a cyberspace information system, where the memoryless technology includes technology which is not affected by generalized disturbance; eliminating a memory of the cyberspace information system on an effect of random disturbance by using a redundancy and replacement mechanism; and eliminating a memory of the cyberspace information system on an effect of non-random disturbance by eliminating a memory of a program running in the cyberspace information system and/or data in the cyberspace information system. The present solution can block a memory of the cyberspace information system on an error caused by the generalized disturbance including the non-random disturbance and the random disturbance, thereby improving security of the cyberspace information system.Type: ApplicationFiled: June 7, 2021Publication date: February 2, 2023Inventors: Lei HE, Jiangxing WU, Qinrang LIU, Ke SONG, Quan REN, Jun ZHOU, Min FU, Weili ZHANG, Ruihao DING, Yiwei GUO
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Publication number: 20220378704Abstract: A process for the preparation of a nanoparticulate active ingredient comprises the steps of: a) providing a solvent, a pharmaceutical active ingredient dissolved in the solvent, a liquid antisolvent and a stabilizer which is dissolved in the solvent or in the antisolvent and wherein the antisolvent is miscible in the solvent; b) mixing the solvent, the active ingredient, the antisolvent and the stabilizer in a micromixer, thereby obtaining a suspension comprising a precipitate of the active ingredient, the solvent and the antisolvent. The active ingredient precipitate is present in the form of nanoparticles having an average particle size of ?10 nm to ?999 nm and a particle size distribution, determined by dynamic light scattering (DLS) according to ISO 22412:2017, having a polydispersity index of ?0.2.Type: ApplicationFiled: October 5, 2020Publication date: December 1, 2022Inventors: Qingbai CAI, Leslaw MLECZKO, Werner HOHEISEL, Shizhe TIAN, Min FU
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Patent number: 11378858Abstract: The present disclosure provides a liquid crystal display panel, a color resistance layer is disposed on an array substrate corresponding to the bonding terminals, a plurality of conductive components are disposed on a surface of the color resistance layer and one-to-one electrically connected to metal lines, a first silver line is in contact with each of the metal lines and the conductive components corresponding to the metal lines in a thickness direction of the liquid crystal display panel, and a second silver line is in contact with a surface of the conductive components near the color filter substrate, to improve display effect of the liquid crystal display panel.Type: GrantFiled: December 5, 2019Date of Patent: July 5, 2022Inventor: Min Fu
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Publication number: 20220115911Abstract: A wireless power transmitting terminal and control method are disclosed. The wireless power transmitting terminal including an inverter circuit, a resonance circuit and a controller, wherein in a frequency detection state, an alternating current of the inverter circuit is controlled to switch between different candidate frequencies, so as to determine a resonance frequency and a maximum peak value of an electrical parameter of the alternating current at the resonance frequency, and determine an operating state of the power transmitting terminal according to the change of the maximum peak value. Therefore, the wireless power transmitting terminal can dynamically adjust in real time a preset operating state thereof, thereby improving the device adaptability, and avoiding the damage of the device to be charged.Type: ApplicationFiled: September 28, 2021Publication date: April 14, 2022Applicant: NINGBO WEIE ELECTRONICS TECHNOLOGY LTD.Inventors: Feng Yu, Lizhi Xu, Weiyi Feng, Min Fu
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Patent number: D1007041Type: GrantFiled: September 15, 2021Date of Patent: December 5, 2023Assignee: NINGBO FIVEFU TECHNOLOGY LIMITEDInventor: Min Fu