Abstract: The present invention provides Bacillus natto for producing menaquinone-7. Bacillus natto is deposited at the China General Microbiological Culture Collection Center, the accession number being CGMCC No. 21799. The strain has few requirements for nutrients, has a high yield, has mild metabolism, is easy to regulate and control, and is suitable for industrial scale-up.

Abstract: An air conditioner includes an outdoor unit, a plurality of indoor units, and a controller. The outdoor unit includes a first throttling device. The indoor unit includes a second throttling device. The controller is configured to: regulate an opening degree of the first throttling device, so that a first supercooling temperature is within a first supercooling temperature range in a case where the air conditioner is in a cooling mode; regulate opening degrees of a plurality of second throttling devices in a case where the air conditioner is in a heating mode, so that a plurality of second supercooling temperatures are each within a second supercooling temperature range, and an absolute value of a difference between each of the plurality of second supercooling temperatures and an average value of the plurality of second supercooling temperatures is less than or equal to a first threshold.

Abstract: Embodiments of the disclosure relate to methods for metal gapfill of a logic device with lower resistivity. Specific embodiments provide integrated separate tungsten PVD processes with plasma-etch to solve the overhang issue caused by tungsten PVD and the high resistivity caused by nucleation.

Abstract: The present invention provides antibodies that bind specifically to TrkB and methods of using the same. According to certain embodiments, the antibodies of the invention are agonist antibodies that are neuroprotective, as shown by their effect on enhancing the survival of retinal ganglion cells in vitro. As such, these agonist antibodies may be used to treat diseases or disorders of the eye, such as, but not limited to glaucoma. In addition, other neuronal diseases or disorders may benefit from treatment with these agonist antibodies, including any disease or disorder characterized in part by neuronal damage. In certain embodiments, the invention includes antibodies that bind TrkB and mediate cell signaling. The antibodies of the invention may be fully human, non-naturally occurring antibodies.

Abstract: The present invention relates to an electronic device, a wireless communication method, and a computer readable medium. According to one embodiment, the electronic device used for wireless communication comprises a processing circuit. The processing circuit is configured to perform control to send data and information related to retransmission of the data to a target user equipment by means of a sidelink. The processing circuit is further configured to control operation for the retransmission of the data.

Abstract: A multi-station turning tool includes a lower bottom plate mechanism. A first hydraulic pipeline arranged in hydraulic fluid to an upper and an end face clamping hydraulic cylinders; a supporting plate mechanism internally provided with an air-detection pipeline; a positioning mechanism includes a substrate and a plurality of supporting blocks; an upper clamping mechanism includes a V-shaped clamping block connected to an upper clamping big arm that's connected to the upper clamping hydraulic cylinder; an end face clamping mechanism includes an end face clamping block that's connected to an end face clamping big arm that's connected to the end face clamping hydraulic cylinder through a piston ejector rod; an end face clamping air-detection mechanism includes an air pressure detection component, connected to a controller, and is capable of detecting a pressure of the air-detection pipeline to identify working states of the positioning mechanism and the upper clamping mechanisms.

Abstract: In some embodiments, a method transcodes a first location from a spatial region. The first location is associated with a first pattern defining a structure of splitting a location into smaller shapes. A bit string of bits is included for the first pattern in an encoded bitstream. The method determines the first location in the spatial region when the first pattern of the first location can be reused for a second pattern of a second location. The first location is one of a plurality of locations in the spatial region. Information for the second location is included in the encoded bitstream that indicates the first location in the spatial region without including a bit string of bits for the second pattern. The first location allows the bit string of bits for the first pattern to be retrieved for use to decode the second location from the encoded bitstream.

Abstract: A toothed power transmission belt with a smooth back side surface has a back jacket on the back side surface; wherein the back jacket comprises a closed-mesh, knit fabric tube. The fabric tube may be knitted on a circular weft knitting machine and may be heat set after knitting. The fabric tube may be treated with an epoxy, RFL or other treatment to provide for oil resistance, adhesion, frictional properties, etc.

Abstract: A method includes transcoding a first block from a spatial region. The first block is associated with a first block tree pattern defining a structure of splitting a block into smaller blocks. A bit string of bits for the first block tree pattern is included in an encoded bitstream. The method determines a location of the first block in the spatial region when the first block tree pattern of the first block can be reused for a second block tree pattern of a second block. The spatial region includes blocks and the location is based on the first block being in the spatial region. Information for the second block is included in the encoded bitstream that indicates the location of the first block in the spatial region. The location allows the bit string for the first block tree pattern to be retrieved for use to decode the second block.

Abstract: Provided, in part, are an anti-human transferrin receptor antigen-binding proteins and fusion proteins comprising an anti-human transferrin receptor antigen-binding proteins (e.g., in scFv, Fab or antibody format) which may be fused to a payload for delivery of the payload to a targeted tissue (e.g., past the blood-brain barrier and to the brain). Payloads include, for example, alpha-glucosidase (GAA) polypeptide. Methods for treating various diseases with such molecules, e.g., glycogen storage diseases, such as Pompe Disease, with the fusions are provided.

Abstract: Nucleic acid constructs and compositions that allow insertion of a multidomain therapeutic protein (e.g., GAA fusion protein) coding sequence into a target genomic locus such as an endogenous ALB locus and/or expression of the multidomain therapeutic protein (e.g., GAA fusion protein) coding sequence are also provided. The nucleic acid constructs and compositions can be used in methods of integration of a multidomain therapeutic protein (e.g., GAA fusion protein) nucleic acid into a target genomic locus, methods of expression of a multidomain therapeutic protein (e.g., GAA fusion protein) in a cell, methods of reducing glycogen accumulation, methods of treating Pompe disease or GAA deficiency in a subject, and method of preventing or reducing the onset of a sign or symptom of Pompe disease in a subject, including neonatal cells and subjects.

Abstract: In some embodiments, a method performs a first calculation to select an anchor point based on a first reference block in a first reference frame and a second reference block in a second reference frame. The first reference frame is selected as the anchor point. A third reference block in the second reference frame is selected based on the first reference frame being selected as the anchor point. The method performs a second calculation to select the anchor point based on the first reference block in the first reference frame and the third reference block in the second reference frame and determines whether to use the first reference block and the third reference block as a prediction for a current block based on the second calculation.

Abstract: A method includes transcoding a first block from a spatial region. The first block is associated with a first block tree pattern defining a structure of splitting a block into smaller blocks. A bit string of bits for the first block tree pattern is included in an encoded bitstream. The method determines a location of the first block in the spatial region when the first block tree pattern of the first block can be reused for a second block tree pattern of a second block. The spatial region includes blocks and the location is based on the first block being in the spatial region. Information for the second block is included in the encoded bitstream that indicates the location of the first block in the spatial region. The location allows the bit string for the first block tree pattern to be retrieved for use to decode the second block.

Abstract: Technologies are disclosed for resource mapping during URL changes in multi-tenant distributed computing systems. The distributed computing system may resolve a URL by using a tenant and/or site name extracted from the URL to retrieve an entry in a site map table. The entry includes an address to a database that contains the requested content. After a tenant or site name has been changed, or if the tenant or site have been moved, the distributed computing system will resolve pre-existing URLs to the old entry, resulting in a file not found error. In some embodiments, during an operation that changes a tenant or site name, a redirect URL containing the new tenant and/or site name is added to the old entry. When a request addressed to a URL containing the old tenant and/or site names is received, the distributed system sends a redirect response that includes the redirect URL.

Abstract: A method includes transcoding a first block of a video. The first block is associated with a first block tree pattern defining a structure of splitting a block into smaller blocks. A bit string of bits for the first block tree pattern is included in an encoded bitstream for the video. The method determines that the first block tree pattern of the first block can be reused for a second block tree pattern of a second block and includes information in the encoded bitstream that indicates that the first block tree pattern is to be used to decode the second block from the encoded bitstream.

Abstract: A power transmission belt having a belt body, a tensile cord embedded in the belt body, and a jacket defining a pulley contact surface, where the jacket has been treated on at least the pulley contact surface with an aqueous fabric treatment or dip which includes an aqueous PEEK dispersion as part of the dip. The aqueous dip may further include an epoxy and a rubber latex. The aqueous dip may further include graphene or graphene oxide. The fabric may include aramid or nylon fibers. The jacket may cover the teeth of a toothed belt.

Abstract: Textile reinforced elastomeric composites having a textile reinforcement embedded in an elastomeric matrix. The textile reinforcement includes fibers or yarns and an adhesive treatment applied to the fibers wherein the adhesive treatment comprises graphene or graphene oxide. The textile reinforcement may be a fabric or a tensile cord. The fibers may be polyester, aramid, carbon fiber, glass fiber, PBO, PEN, or polyamide. The adhesive treatment may be an epoxy treatment, an epoxy-latex treatment, an acrylic polymer treatment, a latex treatment, a polyurethane treatment, an RFL treatment, a rubber cement, or combinations thereof. The composite may be in the form of a toothed belt wherein the textile reinforcement is a tooth cover or a helically wound tensile cord embedded in the belt.

Abstract: The present invention provides antibodies that bind specifically to TrkB and methods of using the same. According to certain embodiments, the antibodies of the invention are agonist antibodies that are neuroprotective, as shown by their effect on enhancing the survival of retinal ganglion cells in vitro. As such, these agonist antibodies may be used to treat diseases or disorders of the eye, such as, but not limited to glaucoma. In addition, other neuronal diseases or disorders may benefit from treatment with these agonist antibodies, including any disease or disorder characterized in part by neuronal damage. In certain embodiments, the invention includes antibodies that bind TrkB and mediate cell signaling. The antibodies of the invention may be fully human, non-naturally occurring antibodies.

Abstract: Non-human animal genomes, non-human animal cells, and non-human animals comprising a humanized TRKB locus and methods of making and using such non-human animal genomes, non-human animal cells, and non-human animals are provided. Non-human animal cells or non-human animals comprising a humanized TRKB locus express a human TRKB protein or a chimeric transthyretin protein, fragments of which are from human TRKB. Methods are provided for using such non-human animals comprising a humanized TRKB locus to assess in vivo efficacy of human-TRKB-targeting reagents such as nuclease agents designed to target human TRKB.