Abstract: The invention encompasses methods and test strips for detecting the presence of cerebrospinal fluid (CSF) in a biological sample with a lateral flow device which uses lectin conjugates, anti-antigen conjugates, an immobilized serum line, and an immobilized anti-antigen line.

Abstract: The invention encompasses methods and test strips for detecting the presence of cerebrospinal fluid (CSF) in a biological sample with a lateral flow device which uses lectin conjugates, anti-antigen conjugates, an immobilized serum line, and an immobilized anti-antigen line.

Abstract: Disclosed are a one-pot biosensor and an immunoassay method using the same. The one-pot biosensor includes a photocatalyst substrate deposited with metal nanoparticles; and a reaction pad which is disposed on an upper surface of the photocatalyst substrate and includes a first binding material-fluorescent material complex specifically binding to a molecule to be detected, and the immunoassay method using the same. The one-pot biosensor may detect a target by once solution injection and has a size enough to be portable. Accordingly, since the one-pot biosensor can detect the target by only once solution injection without a washing step, because of a sensor platform capable of being easily used by an individual other than a diagnostic expert, it is predicted to be positioned as a means capable of confirming the health condition of the individual without seeing the doctor, such as a pregnancy diagnostic kit which has been currently commercialized.

Abstract: The invention encompasses methods and test strips for detecting the presence of cerebrospinal fluid (CSF) in a biological sample with a lateral flow device which uses lectin conjugates, anti-antigen conjugates, an immobilized serum line, and an immobilized anti-antigen line.

Abstract: Disclosed is an all-in-one molecular diagnostics device, and more particularly, a molecular diagnostics device comprising a binding pad specifically binding to a diagnostic target molecule, a transfer pad including an elution buffer in a dry state that separates the diagnostic target molecule from the binding pad, and an amplification pad where an amplification reaction for the diagnostic target molecule occurs.

Abstract: The present invention relates to an aptamer screening method, and the aptamer screened by the screening method of the present invention binds to a site other than a site where the antibody binds to the target substance to be applicable in various fields such as sandwich-type biosensors and reduce a significant time without requiring a separate pairing selection process. In addition, such an aptamer has excellent stability and sensitivity compared to conventional preparations comprising an antibody, can be mass-produced at low cost in a short time by a chemical synthesis method, and is easily transformed in various ways to increase a binding force. In addition, the immunoassay method using the aptamer screened by the aptamer screening method of the present invention selectively amplifies only the aptamer binding to the target substance in a heterogeneous sandwich structure to detect a relative fluorescence signal, thereby detecting the target substance sensitively and quickly.

Abstract: The present invention relates to a conjugate for immunodetection, an immunodetection sensor including same, and an immunodetection method and an immunodetection signal amplification method using same. Specifically, the present invention has the technical features of: a conjugate for immunodetection based on lateral flow assay, the conjugate including nanoparticles, a polymer conjugated to the nanoparticles and including a plurality of enzymes, and a first binder conjugated to the surface of the polymer and specifically binding to a target specimen; and a use thereof. Accordingly, detection sensitivity is remarkably improved, thereby enabling ultra-high-sensitivity detection, and various antigens and diseases can be simply, quickly, and effectively diagnosed, so that the present invention can be advantageously used.

Abstract: Disclosed is an amplification/detection kit comprising: a sample pad on which a PCR reaction solution is placed; a transfer pad positioned in contact with the sample pad; a reaction pad into which the PCR reaction solution flowing from the sample pad through the transfer pad flows and which includes a gold thin film deposited on a first surface; and a sealing tape configured to cover and seal a first surface of the transfer pad and a first surface of the reaction pad.

Abstract: The invention encompasses methods and test strips for detecting the presence of cerebrospinal fluid (CSF) in a biological sample comprising removing sialo-transferrin and selectively detecting or measuring asialo-transferrin in the biological sample.

Abstract: Disclosed are a one-pot biosensor and an immunoassay method using the same. The one-pot biosensor includes a photocatalyst substrate deposited with metal nanoparticles; and a reaction pad which is disposed on an upper surface of the photocatalyst substrate and includes a first binding material-fluorescent material complex specifically binding to a molecule to be detected, and the immunoassay method using the same. The one-pot biosensor may detect a target by once solution injection and has a size enough to be portable. Accordingly, since the one-pot biosensor can detect the target by only once solution injection without a washing step, because of a sensor platform capable of being easily used by an individual other than a diagnostic expert, it is predicted to be positioned as a means capable of confirming the health condition of the individual without seeing the doctor, such as a pregnancy diagnostic kit which has been currently commercialized.

Abstract: A membrane strip sensor according to an embodiment of the present disclosure, the membrane strip sensor includes: a support; a sample pad; a conjugate pad; a reaction membrane; a absorption pad; and a secondary reagent pad.

Abstract: Techniques for modulating peripheral nerves using focused ultrasound (FUS) are provided. Methods include locating a peripheral nerve in a subject using an imaging probe, providing a FUS having one or more ultrasound parameters to a location on the peripheral nerve, and modulating the peripheral nerve. The methods can further include eliciting and measuring a physiological response from the FUS modulation, generating tissue deformation in the vicinity of the FUS modulation, and imaging the nerve and the tissue deformation simultaneously with FUS modulation. Systems for use in the modulation of peripheral nerves are also provided.

Abstract: A multiple molecular diagnosis chip structure according to one embodiment of the present invention comprises: a reaction pad; a channel pad; and a transfer pad.

Abstract: The present invention relates to a reusable optical fiber aptasensor using a photo-thermal effect, and more particularly, to a reusable optical fiber aptasensor using white light and a laser. The aptasensor includes a light emitting unit for selectively emitting one of white light and a laser, a sensor unit including a plurality of aptamers, a plurality of gold nanorods, and a silver mirror, a detector for analyzing a wavelength of inputted light, and an optical fiber for connecting the light emitting unit with the sensor unit, and connecting the detector with the sensor unit, wherein the light emitted from the light emitting unit is totally reflected in the optical fiber and irradiated to the sensor unit, and light reflected from the silver mirror of the sensor unit is irradiated to the detector. Accordingly, the aptasensor easily measures concentration of a target material in a sample using the optical fiber.

Abstract: Disclosed is a platform detecting glycated hemoglobin as an indicator for diabetes in the blood based on upconverting nanoparticles excited by near-infrared light and luminescence resonance energy transfer.

Abstract: A colorimetric detection sensor includes a porous membrane and a detection unit formed on the porous membrane. The detection unit includes a water-soluble chitosan derivative and a color-developing reagent.

Abstract: A control method for a motor-driven vehicle is provided. The method includes calculating a correction torque of a drive motor through a difference between speeds of wheels or a variance rate of the difference between speeds of the wheels and comparing a calculated correction torque with a current required torque of the drive motor. When the calculated correction torque is greater than the current required torque, the drive motor is operated based on the current required torque. When the calculated correction torque is less than or equal to the current required torque, the drive motor is operated based on the calculated correction torque, or the required torque of the drive motor is corrected to correspond to the calculated correction torque and the drive motor is operated based on a corrected required torque of the drive motor.

Abstract: Techniques for selective modulation of motor neuronal activity in a peripheral nervous system using a focused ultrasound assembly are provided. Methods include adjusting a pulse repetition frequency parameter of a focused ultrasound to selectively modulate a location on a peripheral nerve and modulating the peripheral nerve with the focused ultrasound to increase a temperature of the peripheral nerve. The modulating can comprise one or more of exciting and inhibiting the peripheral nerve with the focused ultrasound, either separately or in combination. Methods can further include locating the peripheral nerve using an imaging probe, monitoring a physiological response to the modulating, and changing the one or more ultrasound parameters in response to the physiological response. Systems for use in the modulation of peripheral nerves are also provided.

Abstract: Techniques for modulating peripheral nerves using focused ultrasound (FUS) are provided. Methods include locating a peripheral nerve in a subject using an imaging probe, providing a FUS having one or more ultrasound parameters to a location on the peripheral nerve, and modulating the peripheral nerve. The methods can further include eliciting and measuring a physiological response from the FUS modulation, generating tissue deformation in the vicinity of the FUS modulation, and imaging the nerve and the tissue deformation simultaneously with FUS modulation. Systems for use in the modulation of peripheral nerves are also provided.

Abstract: A control method for a motor-driven vehicle is provided. The method includes calculating a correction torque of a drive motor through a difference between speeds of wheels or a variance rate of the difference between speeds of the wheels and comparing a calculated correction torque with a current required torque of the drive motor. When the calculated correction torque is greater than the current required torque, the drive motor is operated based on the current required torque. When the calculated correction torque is less than or equal to the current required torque, the drive motor is operated based on the calculated correction torque, or the required torque of the drive motor is corrected to correspond to the calculated correction torque and the drive motor is operated based on a corrected required torque of the drive motor.