Patents by Inventor Min Luo

Min Luo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250011430
    Abstract: Provided are an anti-B7H3 antibody and the use thereof. A variable region of the antibody comprises amino acid sequences as shown in SEQ ID NOs: 25-39. The anti-B7H3 antibodies 26B6, 6F7, 2B8, and 23H1 have a significant binding capability to B7H3, can not only bind to purified or free B7H3 protein, but also can bind to B7H3 protein on a cell surface; and after humanized modification, the affinity between the antibody and B7H3 is further improved, and the antibody has important application prospects in clinical diagnosis and/or treatment of B7H3-positive tumors.
    Type: Application
    Filed: December 15, 2020
    Publication date: January 9, 2025
    Inventors: Min Luo, Guangchao Li, Zhao Zhou, Xuejun Wang
  • Publication number: 20240380788
    Abstract: Methods and devices for encrypting Network Configuration Protocol (NETCONF) datastore in communication networks are disclosed. One of the methods is performed by a device using NETCONF. The method comprises enabling a function for NETCONF Datastore Security (DS-SEC). The method further comprises publishing a first indication indicating that the device supports the NETCONF DS-SEC function.
    Type: Application
    Filed: August 16, 2021
    Publication date: November 14, 2024
    Inventors: Daiying Liu, Renwang Liu, Min Luo
  • Patent number: 12087290
    Abstract: A data processing method based on simultaneous interpretation, applied to a server in a simultaneous interpretation system, including: obtaining audio transmitted by a simultaneous interpretation device; processing the audio by using a simultaneous interpretation model to obtain an initial text; transmitting the initial text to a user terminal; receiving a modified text fed back by the user terminal, the modified text being obtained after the user terminal modifies the initial text; and updating the simultaneous interpretation model according to the initial text and the modified text.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: September 10, 2024
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Jingliang Bai, Caisheng Ouyang, Haikang Liu, Lianwu Chen, Qi Chen, Yulu Zhang, Min Luo, Dan Su
  • Publication number: 20240229037
    Abstract: An siRNA targeting 170-hydroxysteroid dehydrogenase type 13 and a siRNA conjugate. Also disclosed are a pharmaceutical composition, cell or kit containing the siRNA, and a method for using the siRNA for the treatment and/or prevention of subjects suffering from HSD17B13-related disorders (such as chronic fibroinflammatory liver disease).
    Type: Application
    Filed: April 22, 2022
    Publication date: July 11, 2024
    Inventors: Jinyu HUANG, Yanfen HUANG, Min LUO, Fang ZHANG
  • Patent number: 12033621
    Abstract: A method for speech recognition based on language adaptivity comprises obtaining voice data of a user. The method also comprises extracting, based on the obtained voice data, a phoneme feature representing pronunciation phoneme information. The phoneme feature is input to a pre-trained language discrimination model that is pre-trained based on a multilingual corpus. A language discrimination result corresponding to the phoneme feature and in accordance with the language discrimination model is obtained. The method also comprises obtaining a speech recognition result of the voice data based on a language acoustic model of a language corresponding to the language discrimination result. The method further comprises determining a speech recognition result of the voice data based on a language acoustic model of a language corresponding to the language discrimination result.
    Type: Grant
    Filed: April 15, 2021
    Date of Patent: July 9, 2024
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Dan Su, Tianxiao Fu, Min Luo, Qi Chen, Yulu Zhang, Lin Luo
  • Publication number: 20240172401
    Abstract: A chassis for an edge device includes a cabinet and a heat exchange component. The heat exchange component is disposed in a space enclosed by the cabinet. The space in the cabinet is divided into a first space and a second space for placement an electronic device. The heat exchange component performs heat transfer between the first space and the second space. A first air inlet and a first air outlet are disposed in the first space, and an airflow entering from the first air inlet flows through a first surface of the heat exchange component and exits from the first air outlet.
    Type: Application
    Filed: January 29, 2024
    Publication date: May 23, 2024
    Applicant: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Chenghua Liu, Xiaochu Li, Min Luo, Xiaolong Yan
  • Publication number: 20240122982
    Abstract: A chimeric antigen receptor fusion protein co-expressing IL-7 and CCR2b, and application thereof are provided. The fusion protein includes a chimeric antigen receptor, a 2A peptide, IL-7, a 2A peptide and CCR2b which are sequentially linked in series.
    Type: Application
    Filed: March 30, 2021
    Publication date: April 18, 2024
    Inventors: Guangchao LI, Min LUO, Wen DING, Xuejun WANG
  • Publication number: 20240059776
    Abstract: Provided are an anti-B7H3 chimeric antigen receptor and an application thereof. The anti-B7H3 chimeric antigen receptor comprises an antigen binding domain, a hinge region, a transmembrane domain and a signaling transfer structural domain. The antigen binding domain is an anti-human B7H3 antibody. The anti-B7H3 chimeric antigen receptor has a specific targeting effect on B7H3-positive tumor cells, T cells that express the anti-B7H3 chimeric antigen receptor have significant killing effects in vitro and in vivo, can effectively remove the B7H3-positive tumor cells, and having important significance in the field of tumor therapy.
    Type: Application
    Filed: December 22, 2020
    Publication date: February 22, 2024
    Applicant: GUANGZHOU BIO-GENE TECHNOLOGY CO., LTD
    Inventors: Guangchao Li, Min Luo, Wen Ding, Zhao Zhou, Xuejun Wang
  • Publication number: 20240050472
    Abstract: Provided are an anti-Claudin 18.2 antigen-binding fragment or antibody, and the use thereof. CDR3 of a heavy chain variable region of the antigen-binding fragment comprises an amino acid sequence shown in SEQ ID NO. 3. CDR3 of a light chain variable region of the antigen-binding fragment comprises an amino acid sequence shown in SEQ ID NO. 6. The provided antigen-binding fragment and anti-Claudin 18.2 antibody can specifically bind to a variety of sources of Claudin 18.2 proteins, have no binding effect on other proteins, and have a high specificity. In addition, a chimeric antigen receptor and a CAR-T cell prepared by means of the antibody have obvious cytotoxicity on cells stably expressing the Claudin 18.2 protein.
    Type: Application
    Filed: December 22, 2020
    Publication date: February 15, 2024
    Applicant: GUANGZHOU BIO-GENE TECHNOLOGY CO., LTD
    Inventors: Min Luo, Guangchao Li, Wen Ding, Zhao Zhou, Xuejun Wang
  • Patent number: 11898267
    Abstract: Crystalline NH4Be2BO3F2 or Be2BO3F (abbreviated as BBF) has nonlinear optical effect, is not deliquescent in the air, is chemically stable. They can be used in a variety of nonlinear optical fields and will pioneer the nonlinear optical applications in the deep UV band.
    Type: Grant
    Filed: November 11, 2020
    Date of Patent: February 13, 2024
    Assignee: FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCES
    Inventors: Ning Ye, Guang Peng, Min Luo, Ge Zhang, Yu Chen
  • Patent number: 11797084
    Abstract: This application discloses a method for training a gaze tracking model, including: obtaining a training sample set; processing the eye sample images in the training sample set by using an initial gaze tracking model to obtain a predicted gaze vector of each eye sample image; determining a model loss according to a cosine distance between the predicted gaze vector and the labeled gaze vector for each eye sample image; and iteratively adjusting one or more reference parameters of the initial gaze tracking model until the model loss meets a convergence condition, to obtain a target gaze tracking model. According to the solution provided in this application, a gaze tracking procedure is simplified, a difference between a predicted value and a labeled value can be better represented by using the cosine distance as a model loss to train a model, to improve prediction accuracy of the gaze tracking model.
    Type: Grant
    Filed: May 18, 2021
    Date of Patent: October 24, 2023
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Zheng Zhou, Xing Ji, Yitong Wang, Xiaolong Zhu, Min Luo
  • Patent number: 11763677
    Abstract: An approach is provided for dynamically identifying a danger zone for a predicted traffic accident and generating a warning about the accident. From a monitoring device at a first location, information about traffic conditions for vehicles at time T0 and at least one subsequent time T0+t is received. Based on speeds of the vehicles and a fixed distance from the first location, a response time is calculated. Within the response time, a dual artificial intelligence (AI) model using shallow and deep learners applied on historical accident data is employed. Based on the dual AI model and the traffic conditions, an accident involving vehicle(s) in the traffic is predicted to occur in a zone. A warning about the accident is generated and sent to device(s) in the vehicle(s). The warning is presented to driver(s) of the vehicle(s).
    Type: Grant
    Filed: December 2, 2020
    Date of Patent: September 19, 2023
    Assignee: International Business Machines Corporation
    Inventors: Kuo-Liang Chou, Min Luo, Der-Joung Wang, Xiang Yu Yang, Ci-Wei Lan
  • Publication number: 20230287418
    Abstract: Disclosed is a modified siRNA with a reduced off-target activity. The siRNA comprises a sense strand and an antisense strand, wherein the antisense strand contains a chemical modification as represented by formula (I) or a tautomeric modification thereof in at least one nucleotide position from position 2 to position 8 of 5? region thereof. A conjugate, a pharmaceutical composition, a cell or a kit containing the siRNA, and the medical use of the siRNA, the conjugate and/or the pharmaceutical composition thereof are also disclosed. Further disclosed are compounds as represented by formula (II) and formula (III) or tautomers thereof, and preparation methods therefor.
    Type: Application
    Filed: August 4, 2021
    Publication date: September 14, 2023
    Inventors: Jinyu HUANG, Min LUO, Ke YIN
  • Patent number: 11749262
    Abstract: A keyword detection method includes: obtaining an enhanced speech signal of a to-be-detected speech signal, the enhanced speech signal corresponding to a target speech speed; performing speed adjustment on the enhanced speech signal to obtain a first speed-adjusted speech signal having a first speech speed, the first speech speed being different from the target speech speed; obtaining a first speech feature signal according to the first speed-adjusted speech signal; obtaining a detection result according to a first keyword detection result corresponding to the first speech feature signal, the detection result indicating whether a target keyword exists in the to-be-detected speech signal; and performing an operation corresponding to the target keyword in response to determining that the target keyword exists according to the detection result.
    Type: Grant
    Filed: June 10, 2021
    Date of Patent: September 5, 2023
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Yi Gao, Ian Ernan Liu, Min Luo
  • Patent number: 11715497
    Abstract: A video editing method, apparatus and storage medium are provided. The method includes obtaining an object, the object including one or more images; determining a content element of the object for video editing, the content element having a content type identifier; determining a material set identifier corresponding to the content type identifier according to a first behavior tree logic; determining a video editing material set corresponding to the material set identifier; and obtaining an edited video according to the content element and the video editing material set.
    Type: Grant
    Filed: May 7, 2021
    Date of Patent: August 1, 2023
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Xiao Long Zhu, Shenghui Huang, Lijian Mei, Wei Dong Chen, Shao Bin Lin, Yi Tong Wang, Xing Ji, Jie Fan, Min Luo, Wanyu Huang, Yuan Fang, Ren Jian Chen
  • Patent number: 11542318
    Abstract: The present disclosure provides use of chemokine receptor CXCR5, wherein CAR-T cells with enhanced chemotaxis are obtained by modifying chimeric antigen receptor T cells (CAR-T cells) utilizing the chemotactic signal between CXCR5 and its ligand CXCL13. The chemokine receptor CXCR5 can guide CAR-T cells to migrate to tumors. It has an excellent ability to enhance the chemotaxis of CAR-T cells, can specifically clear tumor cells, and effectively solve the problem of poor efficacy of the existing CAR-T therapy for solid tumors, thereby exhibiting broad application prospects and great market value.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: January 3, 2023
    Assignee: GUANGZHOU BIO-GENE TECHNOLOGY CO., LTD.
    Inventors: Guangchao Li, Min Luo, Jintao Guo, Wenjun Mo, Wen Ding
  • Publication number: 20220396626
    Abstract: Provided is an anti-CLL1 antibody and an application thereof. The variable region of the anti-CLL1 antibody includes the CDRs of SEQ ID NO: 1 to 6, SEQ ID NO: 5, and SEQ ID NO: 7 to 11 or SEQ ID NO: 12 to 17. The anti-CLL1 antibody of the present application has significant binding ability to both free and cell surface CLL1. After humanization, the affinity of the antibody to CLL1 is further improved, and it has important application prospect in the clinical diagnosis and/or treatment of tumors.
    Type: Application
    Filed: December 22, 2020
    Publication date: December 15, 2022
    Inventors: Min Luo, Guangchao Li, Wen Ding, Zhao Zhou, Xuejun Wang
  • Patent number: 11507975
    Abstract: A method of generating content information that matches at least one stored keyword is described. At least one keyword associated with content information is stored. At least one previously searched keyword in a search record is matched with the at least one stored keyword associated with the content information. First-category mapping data is generated based on a first mapping between the matched at least one stored keyword and the at least one previously searched keyword. Second-category mapping data is generated based on the content information and the at least one stored keyword. A received target keyword is determined to be included in the first-category mapping data. In response to the received target keyword, which is included in the first-category mapping data, circuitry of a terminal searches for the content information associated with the target keyword in the second-category mapping data and displays the content information.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: November 22, 2022
    Assignee: Tencent Technology (Shenzhen) Company Limited
    Inventors: Bing Gong, Min Luo, Jianchen Zhu, Li Huang
  • Publication number: 20220299528
    Abstract: A reagent, test paper, a reagent kit, and a test paper kit for detecting a sulfhydryl compound, and a preparation method thereof are provided. The reagent is obtained by mixing a phosphotungstic acid (PTA) reagent, an acetate buffer, and a shield reagent in a specified ratio. The test paper is composed of porous water-absorbent paper and a dry detection reagent dispersed thereon. The reagent is based on principle innovation. When in use, the reagent is directly mixed with urine to be tested in a volume ratio of 2:1, a resulting mixture is allowed to stand for 10 min to 15 min, and then a result can be directly determined by naked eyes. The reagent overcomes the shortcoming of requiring a control sample to assist in the determination of a result in existing methods, and has the advantages of simple operation, safety and non-toxicity, and rapid detection.
    Type: Application
    Filed: August 19, 2020
    Publication date: September 22, 2022
    Applicant: HANGZHOU AOGO MEDICAL CO., LTD.
    Inventors: Min LUO, Zhijian HUANG, Junfeng ZHANG
  • Patent number: D979550
    Type: Grant
    Filed: April 26, 2022
    Date of Patent: February 28, 2023
    Assignee: Guizhou Chuyi Electronic Commerce Co., Ltd
    Inventor: Min Luo