Abstract: Disclosed herein are methods for the isolation and purification of antibodies wherein the use of an affinity chromatographic step results in an antibody composition sufficiently pure for pharmaceutical uses. The methods described herein comprise pH viral reduction/inactivation, ultrafiltration/diafiltration, affinity chromatography, preferably Protein A affinity, ion exchange chromatography, and hydrophobic chromatography. Further, the present invention is directed toward pharmaceutical compositions comprising one or more antibodies of the present invention.

Abstract: An apparatus and method for controlling a velocity of a cooling fan using a timer and a temperature sensor in a set-top box (STB) are provided. An apparatus for controlling a velocity of a cooling fan in an STB may include a temperature sensor unit to change a resistor to be in inverse proportion to an internal temperature, using a thermistor, a timer unit to generate a pulse signal using a capacitor and the resistor of the temperature sensor unit, a switching unit to turn on/off applied voltage, using the generated pulse signal, and a power source unit to apply the voltage to the switching unit.

Abstract: A nonvolatile memory device and a method of manufacturing thereof are provided. The method includes forming a floating gate on a substrate, forming a dielectric layer to conform to a shape of the floating gate, forming a conductive layer to form a control gate on the substrate, the control gate covering the floating gate and the dielectric layer, forming a photoresist pattern on one side of the conductive layer, forming the control gate in the form of a spacer to surround sides of the floating gate, the forming of the control gate including performing an etch-back on the conductive layer until a portion of the dielectric layer on the floating gate is exposed, and forming a poly pad, to which a plurality of contact plugs are connected, on one side of the control gate, the forming of the poly pad including removing the photoresist pattern.

Abstract: Embodiments of the present invention disclose a method and an apparatus for detecting an ONU, and a passive optical network system. The method includes detecting an identity code of an ONU in an open uplink empty window or an empty timeslot, and determining that an ONU corresponding to the identity code of the ONU is a rogue ONU according to the identity code of the ONU. A corresponding apparatus and passive optical network system are also provided in the embodiments of the present invention. In the passive optical network system, a rogue ONU is detected and determined quickly and efficiently, and an effect on an uplink service is reduced.

Abstract: The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.

Abstract: The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.

Abstract: A nonvolatile memory device and a method of manufacturing thereof are provided. The method includes forming a floating gate on a substrate, forming a dielectric layer to conform to a shape of the floating gate, forming a conductive layer to form a control gate on the substrate, the control gate covering the floating gate and the dielectric layer, forming a photoresist pattern on one side of the conductive layer, forming the control gate in the form of a spacer to surround sides of the floating gate, the forming of the control gate including performing an etch-back on the conductive layer until a portion of the dielectric layer on the floating gate is exposed, and forming a poly pad, to which a plurality of contact plugs are connected, on one side of the control gate, the forming of the poly pad including removing the photoresist pattern.

Abstract: The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.

Abstract: A vertical transistor includes a gate isolating layer flanking a stack of a source layer, a resilient active unit and a drain layer, and a gate layer formed on the gate isolating layer. The active unit includes an active layer formed between first and second barrier layers each having a thickness ranging from 4 nm to 40 nm. When an input voltage including a DC component and a ripple component is applied to the source layer, the active unit periodically vibrates as a result of the ripple component of the input voltage such that an induced AC current is generated based on a control voltage applied to the gate layer to flow to the drain layer. The induced AC current flowing to the drain layer serves as an AC output generated by the vertical transistor based on the input voltage. A method of enabling a vertical transistor to generate an AC output is also disclosed.

Abstract: A vertical transistor includes a gate isolating layer flanking a stack of a source layer, a resilient active unit and a drain layer, and a gate layer formed on the gate isolating layer. The active unit includes an active layer formed between first and second barrier layers each having a thickness ranging from 4 nm to 40 nm. When an input voltage including a DC component and a ripple component is applied to the source layer, the active unit periodically vibrates as a result of the ripple component of the input voltage such that an induced AC current is generated based on a control voltage applied to the gate layer to flow to the drain layer. The induced AC current flowing to the drain layer serves as an AC output generated by the vertical transistor based on the input voltage. A method of enabling a vertical transistor to generate an AC output is also disclosed.

Abstract: Surface coverings, such as floor coverings, with an interlocking design are described. Methods of making the surface coverings are further described.

Abstract: The present invention generally relates to novel processes for protein purification in high salt solutions such as cell culture broth by increasing the dynamic binding capacity of a resin with the addition of polyethylene glycol.

Abstract: The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.

Abstract: The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.

Abstract: A nonvolatile memory cell and a method for fabricating the same can secure stable operational reliability as well as reducing a cell size. The nonvolatile memory cell includes a drain region formed in a substrate, a source region formed in the substrate to be separated from the drain region, a floating gate formed over the substrate between the drain region and the source region, a halo region formed in the substrate in a direction that the drain region is formed, a dielectric layer formed on sidewalls of the floating gate, and a control gate formed over the dielectric layer to overlap with at least one sidewall of the floating gate.

Abstract: Disclosed herein are methods for the isolation and purification of antibodies wherein the use of an affinity chromatographic step results in an antibody composition sufficiently pure for pharmaceutical uses. The methods described herein comprise pH viral reduction/inactivation, ultrafiltration/diafiltration, affinity chromatography, preferably Protein A affinity, ion exchange chromatography, and hydrophobic chromatography. Further, the present invention is directed toward pharmaceutical compositions comprising one or more antibodies of the present invention.

Abstract: A method and system for generating wrappers for hierarchically organized documents by jointly optimizing template detection and wrapper generation is provided. A wrapper generation system generates a wrapper for documents with similar templates by identifying a cluster of document trees and generating a wrapper tree for the cluster. A wrapper tree defines the wrapper for documents that match the template of the cluster. The wrapper generation system clusters document trees by generating a wrapper tree for the cluster based on an initial document tree. The wrapper generation system then repeatedly determines whether any other document tree matches or nearly matches the wrapper tree for the cluster and, if so, adds the document tree to the cluster and adjusts the wrapper tree as appropriate so that all the document trees, including the newly added one, match the wrapper tree.

Abstract: Surface coverings, such as floor coverings, with an interlocking design are described. Methods of making the surface coverings are further described.

Abstract: The present invention generally relates to non-ethylene diamine like compounds that prevent and/or delay carbamylation of peptides.

Abstract: A method and system for generating wrappers for hierarchically organized documents by jointly optimizing template detection and wrapper generation is provided. A wrapper generation system generates a wrapper for documents with similar templates by identifying a cluster of document trees and generating a wrapper tree for the cluster. A wrapper tree defines the wrapper for documents that match the template of the cluster. The wrapper generation system clusters document trees by generating a wrapper tree for the cluster based on an initial document tree. The wrapper generation system then repeatedly determines whether any other document tree matches or nearly matches the wrapper tree for the cluster and, if so, adds the document tree to the cluster and adjusts the wrapper tree as appropriate so that all the document trees, including the newly added one, match the wrapper tree.