Abstract: An anti-IL5 nanoantibody, and a coding sequence for coding the anti-IL5 nanoantibody, a corresponding expression vector, a host cell capable of expressing the anti-IL5 nanoantibody, and a method for producing the anti-IL5 nanoantibody are provided. The nanoantibody can specifically recognize IL5 from humans and cynomolgus monkeys, does not recognize IL5 from mice, and has a good binding activity. The nanoantibody has a good IL5/IL5R blocking activity. The blocking activity is obviously superior to that of a control antibody Nucala. The nanoantibody can effectively inhibit the proliferation of TF-1 cells induced by IL5, and the inhibition activity thereof is superior to that of the control antibody Nucala. The expression yield of the nanoantibody in Pichia pastoris can reach 13 g/L, and the purity of target protein expressed in the supernatant is high.

Abstract: An iron-potassium-cerium-based composite oxide catalyst, its preparation and application thereof are provided. The catalyst has metal elements Fe, K and Ce, as well as a metal element M that is at least one selected from the group consisting of Group IIA metal elements, Group VIB metal elements other than Cr and Group IVA metal elements. The catalyst has a total alkali content of 0.32-0.46 mmol/g, and a strong alkali content of 0.061-0.082 mmol/g. When used for dehydrogenation of alkyl aromatics, the catalyst shows high selectivity, high catalytic activity and high stability, provides less by-products, and has the characteristics of low material consumption and low power consumption, even at a low dehydrogenation temperature and an ultralow steam-to-oil ratio.

Abstract: The present disclosure relates to an electronic device, a wireless communication method and a computer-readable medium. According to one embodiment, an electronic device for wireless communication comprises a processing circuit, wherein the processing circuit is configured to conduct control so as to send a reference signal for a direct link to the other user equipment or to receive same from the other user equipment; the processing circuit is also configured to conduct control so as to carry out beamforming-based direct link communication with the other user equipment; and at least one of a sending beam and a receiving beam for direct link communication is determined based on the measurement of the reference signal.

Abstract: This disclosure provides methods for treating cancer and for ameliorating cytokine release syndrome in a subject with a tumor. The methods include administering to a subject in need thereof a bispecific anti-CD20/anti-CD3 antibody before administering to the subject an anti-PD-1 antibody. The disclosed methods represent effective therapies for cancer, e.g, B-cell malignancies, with mitigation of the potential life-threatening effects of cytokine release syndrome (CRS).

Abstract: A method for preparing lithium borohydride by means of room temperature solid phase ball milling, comprising the following steps: uniformly mixing a magnesium-containing reducing agent and a lithium metaborate-containing reducing material under a non-oxidizing atmosphere at room temperature, performing solid phase ball milling, isolating and purifying to obtain lithium borohydride. The method has the advantages of having a simple process, having a controllable and adjustable reaction procedure, having mild reaction conditions, energy consumption being low, costs being low, and output being high, while creating no pollution, being safe and cyclically using boron resources, having important practical significance.

Abstract: A power tool includes a power tool body. The power tool body is configured to be adapted to at least a first battery pack having a first nominal voltage and a first output terminal set and a second battery pack having a second nominal voltage and a second output terminal set, where the first nominal voltage is different from the second nominal voltage. The power tool body includes a first input terminal set configured to be selectively electrically connected to one of the first output terminal set and the second output terminal set to supply power to the power tool body.

Abstract: A foldable weighing scale includes first and second steel frames, connecting rods fastened at bottoms of the first and second steel frames, first pressure sensors fastened at ends of the connecting rods away from the first frame, second pressure sensors fastened at ends of the connecting rods away from the second frame, a display fastened on the first steel frame, and a power supply box fastened on the first steel frame. The display and the first and second pressure sensors are battery powered. There is further provided a switch button connected to a power supply box, and a rotating connection component between the first steel frame and second steel frame. The rotating connection component includes a first connector for rotating in the first steel frame and a second connector fastened on the second steel frame. Part between the first connector and second connector can rotate and is detachable.

Abstract: The present invention provides methods for treating, reducing the severity, or inhibiting the growth of cancer (e.g., recurrent ovarian cancer). The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a bispecific antibody that specifically binds Mucin 16 (MUC16) and CD3 alone, or in combination with a therapeutically effective amount of an antibody or antigen-binding fragment thereof that specifically binds to programmed death 1 (PD-1) receptor.

Abstract: The present disclosure relates to an electronic device, a method, and a storage medium for a wireless communication system. Various embodiments of mobility management for multiple transmission and reception points (multi-TRP) are described. In an embodiment, an electronic device for a first TRP includes a processing circuit, where the processing circuit is configured to: in response to that the first TRP and the second TRP are a master TRP and a secondary TRP respectively serving a terminal device, provide measurement configuration information to the terminal device, receive a measurement report from the terminal device, and update TRPs serving the particular terminal device based at least on measurement quality of the first TRP and the second TRP.

Abstract: A composition comprising an amount of one or more agents comprising a hydroxy(C1-10)(COOH) or salt thereof, wherein C1-10 can be substituted or form a ring, a dicarboxylic acid, a purine nucleoside or analog thereof, a pyrimidine nucleoside or an analog thereof, or an amino acid or analog thereof, effective to inhibit inflammation, and methods of using the composition, are provided.

Abstract: Administration regimens for anti-CD3 x anti-CD20 bispecific antibodies that mitigate cytokine release syndrome and infusion-related reaction are disclosed. The methods employ fractional dosing over several weeks of treatment along with administration of a steroid and an antihistamine.

Abstract: The present invention provides a selector material, a selector unit and a preparation method thereof and a memory structure, wherein the selector material comprises at least one of Te, Se and S, that is, the selector material is selected from a simple substance such as Te, Se and S or compounds composed of any of these elements, further, the performance can be improved by doping with elements such as O, N, Ga, In, As and the like, or oxides, nitrides and carbides or other dielectric materials. The selector material in the present invention has the advantages of high turn-on current, simple material, fast switching speed, good repeatability and low toxicity when the selector material is used in the selector unit, which is beneficial to achieving high-density three-dimensional information storage.

Abstract: A turnable headrest includes a headrest body and a headrest rod. The headrest body is wrapped around and hinged to a horizontal rod of the headrest rod, and two vertical rods of the headrest rod are inserted into a seat. The turnable headrest further includes a fixed tooth, a torsion spring, a rotary tooth, and a reset tension spring. A headrest body locking portion, a headrest body rotary tooth portion, and a turned headrest body locking portion are disposed on the fixed tooth. A rotary tooth portion is disposed on the rotary tooth. When the rotary tooth portion is mated with the headrest body locking portion on the fixed tooth, the headrest body is locked at an initial use position. When the rotary tooth portion is mated with the headrest body rotary tooth portion on the fixed tooth, the headrest body is at a turnable position. When the rotary tooth portion is mated with the turned headrest body locking portion on the fixed tooth, the headrest body is locked at a flat position.

Abstract: A method for preparing a static/dynamic three-dimensional (3D) microcrack propagation sensor, a sensor and equipment, belongs to the field of sensor technology.

Abstract: The disclosure provides methods for the isolation, separation, and purification of antibodies. The method comprises an affinity chromatography capture step, anion exchange chromatography polishing step, and cation exchange chromatography polishing step.

Abstract: The present disclosure relates to an electronic device, a wireless communication method and a computer-readable medium. According to one embodiment, an electronic device for wireless communication comprises a processing circuit, wherein the processing circuit is configured to conduct control so as to send a reference signal for a direct link to the other user equipment or to receive same from the other user equipment; the processing circuit is also configured to conduct control so as to carry out beamforming-based direct link communication with the other user equipment; and at least one of a sending beam and a receiving beam for direct link communication is determined based on the measurement of the reference signal.

Abstract: Expanded polypropylene beads are prepared from composite particles using a high-temperature and high-pressure kettle type foaming method. The composite particles include a core layer and a skin layer. The core layer includes one or more of the following components, for example in percentage by mass: 20-40% of polypropylene A, 60-80% of polypropylene B, 0-20% of polypropylene C and 0-10% of a thermal-conductive additive. The skin layer includes one or more of the following components, for example in percentage by mass: 40-80% of polypropylene D and 20-60% of polypropylene E. The composite particles are of a multi-layer structure with the skin layer covering the core layer. A resin of the skin layer is easy to sinter at low temperature and in compatibility with a main substrate resin of the core layer. The core layer resin adopts a selected mixture, which promotes molding expansibility.

Abstract: A construction monitoring method and system for a V-shaped column in an underground foundation pit, a terminal and a storage medium can include the following steps: acquiring different stress-related data at a plurality of preset positions of stand columns in real time; and analyzing and judging whether the change rate of the stress-related data exceeds a preset change rate range or not or whether the stress-related data exceeds a preset stress-related data range or not.

Abstract: The present application relates to a synchronous rectification sampling control circuit, method and chip. The control circuit includes a withstand voltage switch tube Q2, a power supply switch tube Q3, a positive phase power supply driving module, a detection control module, and a negative phase power supply module. The withstand voltage switch tube Q2 includes a withstand voltage source, a withstand voltage grid and a withstand voltage drain, in which the withstand voltage drain is configured to connect a secondary winding power supply circuit in a synchronous rectification circuit of a transformer to obtain a supply voltage and output a positive or negative sampling voltage at the withstand voltage source.