Abstract: A CD47 single-domain antibody and use thereof, and in particularly, a blocking type single-domain antibody for integrin-related protein (CD47) and derivative proteins thereof. In particular, disclosed are an integrin-related protein (CD47) binding molecule and use thereof, particularly in the treatment and/or prevention, or diagnosis of CD47-associated diseases, such as tumors. The CD47 single-domain antibody involved can effectively block the interaction between CD47 and a ligand SIRPa thereof, has good binding activity, blocking activity, affinity and stability, can effectively enhance the phagocytosis of tumor cells by macrophages, and shows significant anti-tumor activity in both a human lymphoma model and a human ovarian cancer model. In addition, the antibody does not cause hemoagglutination in vitro, and shows excellent safety in cynomolgus monkeys.

Abstract: The present invention discloses a high-reliability copper alloy bonding wire for electronic packaging and a preparation method therefor; the bonding wire comprises the following raw material components in percentage by weight: a copper content being 99.75%-99.96%, a tungsten content being 0.01-0.1%, a silver content being 0.01%-0.03%, a scandium content being 0.01%-0.02%, a titanium content being 0.001%-0.03%, a chromium content being 0.001%-0.03%, and an iron content being 0.001%-0.02%. The preparation method therefor comprises: extracting high-purity copper with a purity greater than 99.99%, preparing same as copper alloy ingots, and further preparing same as as-cast copper alloy crude bars, drawing the crude bars to form copper alloy wires, subjecting same to a heat treatment, and then precise drawing, a heat treatment, and cleaning to obtain copper alloy bonding wires of different specifications.

Abstract: The present disclosure provides a system and method of implementing a security algorithm using a reconfigurable processor, the method including: determining a plurality of sub-algorithms for constructing the security algorithm; and configuring the reconfigurable processor to implement the security algorithm according to a first configuration information of each sub-algorithm of the plurality of sub-algorithms and a first combination configuration information indicating a combination connection relationship of each of the sub-algorithms. The present disclosure also provides a system and method of implementing a decryption algorithm using a reconfigurable processor.

Abstract: The present disclosure relates to an electronic device, a wireless communication method and a computer-readable medium. According to one embodiment, an electronic device for wireless communication comprises a processing circuit, wherein the processing circuit is configured to conduct control so as to send a reference signal for a direct link to the other user equipment or to receive same from the other user equipment; the processing circuit is also configured to conduct control so as to carry out beamforming-based direct link communication with the other user equipment; and at least one of a sending beam and a receiving beam for direct link communication is determined based on the measurement of the reference signal.

Abstract: Generating plasma by using dielectric barrier discharge and introducing a dielectric barrier discharge electrode bar into a high-speed vibrating ball milling tank requires that, on one hand, a solid insulation medium on the outer layer of the electrode bar can simultaneously bear high-voltage discharge and mechanical shock failure of the grinding ball, and on the other hand, the high-speed vibrating ball milling device can uniformly process the powder. The discharge space pressure is set to a non-thermal equilibrium discharge state with a pressure of about 102 to 106 Pa, discharge plasmas are introduced to input another kind of effective energy to the processed powder, so as to accelerate refinement of the powder to be processed and promote the alloying process and improve the processing efficiency and the effect of the ball mill.

Abstract: A pharmaceutical composition can include a plurality of liposomes comprising docetaxel and doxorubicin. In various embodiments, a liposome can include (i) an active pharmaceutical ingredient (API) comprising docetaxel and doxorubicin; (ii) a lipid layer comprising an unsaturated phospholipid, a cholesterol, a cationic lipid, and preferably a pegylated phospholipid; and (iii) an aqueous interior, wherein the docetaxel is in the lipid layer and the doxorubicin is crystallized in the aqueous interior. The liposomes can be used to treat a subject, for example, a human subject having cancer. The cancer can be, for example, a lung cancer, preferably non-small cell lung cancer (NSCLC), colon cancer, breast cancer, or liver cancer.

Abstract: An apparatus and method in a wireless communication system, and a computer-readable storage medium. The method comprises: determining, based on at least one or more of resource set configuration information, physical channel information, and service type information, configuration information of one or more parameter sets for a sidelink communication; and controlling a base station to send the determined configuration information of the one or more parameter sets to a user equipment so that the user equipment performs sidelink communication on the basis of the one or more parameter sets, the parameter set comprising at least a subcarrier interval and a cyclic prefix type. The method can flexibly configure the parameter set used for the sidelink communication in NR so as to improve the communication performance of the sidelink communication and meet higher requirements on a series of indicators in an NR scene such as the delay and the system stability.

Abstract: A task allocating method for a reconfigurable processing system is provided by the present disclosure. The method includes determining a use status of a hardware processing resource of the reconfigurable processing system. The hardware processing resource includes m task channels and a reconfigurable computing array, and one task channel controls at least one operator in the reconfigurable computing array at a time to process one task. The number m is a positive integer and allocating a first task in n tasks to be processed according to the use status of the hardware processing resource, so that at least one task channel in the m task channels controls the reconfigurable computing array to process simultaneously at least one task which includes the first task, where the number n is a positive integer. A task allocating system for a reconfigurable processing system is also provided by the present disclosure.

Abstract: Provided is a cardiac virtualization test tank and testing system and method. A test tank is provided that includes a physical heart model representing the structure of the heart and a plurality of electrodes that output simulated biopotential signals based on an EP model representing the electrophysiological activity of the heart. The test system can be used for training, teaching, or validating a cardiac mapping, diagnosis, and/or treatment system, as examples.

Abstract: The invention discloses a preparation method of a WC cemented carbide with adjustable alignment of plate-shape grains. According to the theoretical composition of the cemented carbide, the weighed W powder is composed of two raw W materials with significantly different particle sizes in a certain mass ratio. Also graphite powder and Co powder are weighed. W—C—Co powder is subjected to planetary ball milling with controlled process parameters; then, after plasma-assisted ball milling, W—C—Co composite powder composed of small-sized lamellar W sheets and large-sized lamellar W sheet is obtained; Finally dense cemented carbide containing plate-shape WC grains is obtained by press molding of the ball milled power and in-situ carbonization through sintering at a high temperature. The invention not only provides simple preparation process with low energy consumption, but also can regulate the degree of orientated alignment of the plate-shape WC in the sintered block.

Abstract: Provided is a fluorinated polymer that can impart excellent washing durability and water- and oil-repellency to fibers, said fluorinated polymer having a repeating unit derived from a fluorinated monomer (a) that comprises a first fluorinated monomer (a1) represented by the formula: CH2?C(—X1)—C(?O)—Y1—Z1—Rf1 [wherein X1 represents a halogen atom; Y1 represents —O— or —NH—; Z1 represents a direct bond or a bivalent organic group; and Rf1 represents a fluoroalkyl group having 1 to 20 carbon atoms] and a second fluorinated monomer (a2) represented by the formula: CH2?C(—X2)—C(?O)—Y2—Z2—Rf2 [wherein X2 represents a monovalent organic group or a hydrogen atom; Y2 represents —O— or —NH—; Z2 represents a direct bond or a bivalent organic group; and Rf2 represents a fluoroalkyl group having 1 to 20 carbon atoms].

Abstract: Docetaxel and doxorubicin can be formulated in liposomal pharmaceutical compositions. In various embodiments, the pharmaceutical compositions include (i) a first liposome type comprising a first lipid layer comprising an unsaturated phospholipid, cholesterol or a cholesterol derivative, DC-cholesterol, a cationic lipid, and preferably a pegylated phospholipid, and a first active pharmaceutical ingredient (API) comprising docetaxel in the first lipid layer; and (ii) a second liposome type comprising a second lipid layer, an aqueous interior, and a second API comprising doxorubicin crystallized in the aqueous interior, (iii) where the first liposome type does not comprise doxorubicin and the second liposome type does not comprise docetaxel. The pharmaceutical composition can be used to treat a subject, for example, a human subject having cancer.

Abstract: The present disclosure provides a system and method of implementing a security algorithm using a reconfigurable processor, the method including: determining a plurality of sub-algorithms for constructing the security algorithm; and configuring the reconfigurable processor to implement the security algorithm according to a first configuration information of each sub-algorithm of the plurality of sub-algorithms and a first combination configuration information indicating a combination connection relationship of each of the sub-algorithms. The present disclosure also provides a system and method of implementing a decryption algorithm using a reconfigurable processor.

Abstract: The present invention discloses a nanoporous copper-zinc-aluminum shape memory alloy and a preparation method and an application thereof. According to the method, firstly a pure Cu block, a pure Zn block and a pure Al block are proportioned in a certain mass ratio before being smelted to obtain a copper-zinc-aluminum alloy ingot; the obtained copper-zinc-aluminum alloy ingot is melt spun using a copper roller rapid quenching method under vacuum protection to obtain an ultrathin strip CuZnAl master alloy which is then subjected to an etching treatment with a solution containing chloride ions at a temperature of 0˜80° C. for 10˜300 minutes to obtain a nanoporous Cu/CuZnAl material; and finally the nanoporous CuZnAl material is sealed in a high vacuum quartz tube for a heat treatment to obtain a nanoporous copper-zinc-aluminum shape memory alloy having a superelastic single ? phase at room temperature.

Abstract: Provided are a localization system and method useful in the acquisition and analysis of cardiac information. The localization system and method can be used with systems that perform cardiac mapping, diagnosis and treatment of cardiac abnormalities, as examples, and in the retrieval, processing, and interpretation of such types of information. The localization system and method use high impedance inputs, improved isolation, and relatively high drive currents for pairs of electrodes used to establish a multi-axis coordinate system. The axes can be rotated and scaled to improve localization.

Abstract: A cardiac information dynamic display system comprises: one or more electrodes configured to record sets of electric potential data representing cardiac activity at a plurality of time intervals; and a cardiac information console, comprising: a signal processor configured to: calculate sets of cardiac activity data at the plurality of time intervals using the recorded sets of electric potential data, wherein the cardiac activity data is associated with surface locations of one or more cardiac chambers; and a user interface module configured to display a series of images, each image comprising: a graphical representation of the cardiac activity. Methods of providing cardiac activity data are also provided.

Abstract: A set of multidimensional data is obtained. At least a portion of the set of multidimensional data is processed to generate a set of formatted data, wherein the set of formatted data comprises at least one of attributes, attribute values and statistics on attribute values. A user is enabled to select, on a graphical user interface, an analysis task to be performed on at least a portion of the set of formatted data. One or more visualizations are generated from a set of visualization types for presentation on a graphical user interface to the user. The set of visualization types comprises a first visualization type representing a relationship between two attributes whereby attribute value pairs are represented by varying colors, a second visualization type representing thematic variations over time with respect to values of at least one attribute; and a third visualization type representing values of three attributes comprising one or more histograms.

Abstract: An Sb—Te—Ti phase-change thin-film material applicable to a phase-change memory and preparation thereof. The Sb—Te—Ti phase-change memory material is formed by doping an Sb—Te phase-change material with Ti, Ti forms bonds with both Sb and Te, and the Sb—Te—Ti phase-change memory material has a chemical formula SbxTeyTi100?x?y, where 0<x<80 and 0<y<100?x. When the Sb—Te—Ti phase-change memory material is a Ti—Sb2Te3 phase-change memory material, Ti atoms replace Sb atoms, and phase separation does not occur. The crystallization temperature of the Sb—Te—Ti phase-change memory material is significantly risen, retention is improved, and thermal stability is enhanced; meanwhile, the amorphous state resistance decreases, and the crystalline state resistance increases; and the Sb—Te—Ti phase-change memory material has wide application in phase-change memories.

Abstract: Disclosed are methods for testing the presence and/or activity of glutathione system components and thioredoxin system components during the manufacturing process of disulfide bond-containing proteins. Also disclosed are methods for mitigating reduction of disulfide bonds during the manufacturing process, and for lowering the reduction potential of disulfide bond-containing proteins. Provided are compositions, kits, and methods for mitigating reduction and diminishing reduction potential of disulfide bond-containing proteins during protein manufacturing processes.

Abstract: A task allocating method for a reconfigurable processing system is provided by the present disclosure. The method includes determining a use status of a hardware processing resource of the reconfigurable processing system. The hardware processing resource includes m task channels and a reconfigurable computing array, and one task channel controls at least one operator in the reconfigurable computing array at a time to process one task. The number m is a positive integer and allocating a first task in n tasks to be processed according to the use status of the hardware processing resource, so that at least one task channel in the m task channels controls the reconfigurable computing array to process simultaneously at least one task which includes the first task, where the number n is a positive integer. A task allocating system for a reconfigurable processing system is also provided by the present disclosure.