Patents by Inventor Ming C. Wu
Ming C. Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9227200Abstract: Microfluidic devices in which electrokinetic mechanisms move droplets of a liquid or particles in a liquid are described. The devices include at least one electrode that is optically transparent and/or flexible.Type: GrantFiled: June 1, 2012Date of Patent: January 5, 2016Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Pei-Yu E. Chiou, Kuo-Wei Huang, Igor Y. Khandros, Ming C. Wu
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Publication number: 20150306598Abstract: A microfluidic apparatus can comprise a dielectrophoresis (DEP) configured section for holding a first liquid medium and selectively inducing net DEP forces in the first liquid medium. The microfluidic apparatus can also comprise an electrowetting (EW) configured section for holding a second liquid medium on an electrowetting surface and selectively changing a wetting property of the electrowetting surface. The DEP configured section can be utilized to select and move a micro-object in the first liquid medium. The EW configured section can be utilized to pull a droplet of the first liquid medium into the second liquid medium.Type: ApplicationFiled: April 25, 2014Publication date: October 29, 2015Applicant: Berkeley Lights, Inc.Inventors: Igor Y. Khandros, J. Tanner Nevill, Steven W. Short, Ming C. Wu
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Publication number: 20150306599Abstract: A structure for providing a boundary for a chamber in a microfluidic apparatus can comprise dielectrophoresis (DEP) configurations each having an outer surface and electrowetting (EW) configurations each having an electrowetting surface. The DEP configurations can facilitate generating net DEP forces with respect to the outer surfaces of the DEP configurations to move micro-objects on the outer surfaces, and the EW configurations can facilitate changing wetting properties of the electrowetting surfaces to move droplets of liquid medium on the electrowetting surfaces.Type: ApplicationFiled: April 25, 2014Publication date: October 29, 2015Applicant: Berkeley Lights, Inc.Inventors: Igor Y. Khandros, Daniele Malleo, J. Tanner Nevill, Steven W. Short, Ming C. Wu
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Publication number: 20140124370Abstract: A microfluidic optoelectronic tweezers (OET) device can comprise dielectrophoresis (DEP) electrodes that can be activated and deactivated by controlling a beam of light directed onto photosensitive elements that are disposed in locations that are spaced apart from the DEP electrodes. The photosensitive elements can be photodiodes, which can switch the switch mechanisms that connect the DEP electrodes to a power electrode between an off state and an on state.Type: ApplicationFiled: October 10, 2013Publication date: May 8, 2014Applicant: Berkeley Lights, Inc.Inventors: Steven W. Short, Ming C. Wu
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Publication number: 20140116881Abstract: Individual biological micro-objects can be deterministically selected and moved into holding pens in a micro-fluidic device. A flow of a first liquid medium can be provided to the pens. Physical pens can be structured to impede a direct flow of the first medium into a second medium in the pens while allowing diffusive mixing of the first medium and the second medium. Virtual pens can allow a common flow of medium to multiple ones of the pens.Type: ApplicationFiled: October 22, 2013Publication date: May 1, 2014Applicant: Berkeley Lights, Inc.Inventors: Kevin T. Chapman, Igor Y. Khandros, Gaetan L. Mathieu, J. Tanner Nevill, Ming C. Wu
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Publication number: 20140017791Abstract: Two or more biological micro-objects can be grouped in a liquid medium in a chamber. Grouping can comprise bringing into and holding in proximity or contact the micro-objects in a group, breaching the membrane of one or more of the micro-objects in a group, subjecting one or more of the micro-objects in a group to electroporation, and/or tethering to each other the micro-objects in a group. The micro-objects in the group can then be combined into a single biological object.Type: ApplicationFiled: July 12, 2013Publication date: January 16, 2014Inventors: Kevin T. Chapman, Igor Y. Khandros, Gaetan L. Mathieu, Steven W. Short, Ming C. Wu
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Publication number: 20130319861Abstract: A micro-fluidic device can include a processing mechanism for processing micro-objects in a liquid medium and an outputting mechanism for expressing from the device a droplet of the medium containing one or more of the micro-objects. The outputting mechanism can include an expressing mechanism having a reservoir for holding a quantity of the liquid medium and a striking mechanism for striking and compressing the expressing mechanism to express a droplet of the medium from the expressing mechanism.Type: ApplicationFiled: April 4, 2013Publication date: December 5, 2013Applicant: Berkeley Lights, Inc.Inventors: Igor Y. Khandros, Gaetan L. Mathieu, J. Tanner Nevill, Ming C. Wu
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Publication number: 20120325665Abstract: Microfluidic devices in which electrokinetic mechanisms move droplets of a liquid or particles in a liquid are described. The devices include at least one electrode that is optically transparent and/or flexible.Type: ApplicationFiled: June 1, 2012Publication date: December 27, 2012Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Pei-Yu E. Chiou, Kuo-Wei Huang, Igor Y. Khandros, Ming C. Wu
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Publication number: 20110150502Abstract: Apparatus and method for increasing optical transmission bandwidth in response to chaining, in cascade, one or more slave lasers onto a master laser. Each laser is configured for optical injection locking (OIL) and each slave laser is locked onto the master laser. The first and each subsequent slave laser are detuned to tailor frequency characteristics of apparatus output. The transmitter can be scaled up by cascading additional injection-locked lasers together. The invention supports multiple compatible modulation formats, such as amplitude modulation (AM), phase modulation (PM), and frequency modulation (FM), for tailoring the output to the application of interest, while any type of laser can be used for the master and slave lasers.Type: ApplicationFiled: September 17, 2009Publication date: June 23, 2011Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Xiaoxue Zhao, Erwin K. Lau, Ming C. Wu, Connie Chang-Hasnain, Hyuk-Kee Sung, Devang Parekh
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Patent number: 7727771Abstract: The invention is related to methods and apparatus that manipulate droplets in a microfluidic environment. Advantageously, embodiments of the invention manipulate droplets by controlling the electro-wetting characteristics of a surface with light, thereby inducing a gradient in the surface tension of a droplet. The gradient in the surface tension propels the droplet by capillary force. A variety of operations, such as transporting, joining, cutting, and creating can be performed. Advantageously, embodiments of the invention obviate the need to create a relatively large and complex control electrode array. A plurality of photoconductive cells or a layer of a photoconductive material selectively couples an electrode carrying an electrical bias to otherwise floating conductive cells in response to a beam of light. The electrical bias applied to the conductive cell generates a localized electric field, which can change the contact angle of the droplet, thereby permitting the droplet to be propelled.Type: GrantFiled: August 22, 2005Date of Patent: June 1, 2010Assignee: The Regents of the University of CaliforniaInventors: Pei Yu Chiou, Ming C. Wu
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Patent number: 7378655Abstract: A method for manufacturing a sensing device, such as a bolometer device or other devices. The method includes providing a substrate, e.g., silicon wafer. The method includes forming a first reflection layer overlying the substrate and forming a first electrode layer overlying the substrate. The method includes forming a sacrificial layer overlying a portion of the first reflection layer and a portion of the first electrode layer. The sacrificial layer is patterned using photolithography techniques. The patterned sacrificial layer corresponds to a cavity region. The method also forms a second electrode layer overlying the sacrificial layer and forms an elastic layer overlying the patterned sacrificial layer. The elastic layer encloses the cavity region corresponding to the patterned sacrificial layer. The method releases the sacrificial layer to form an opening in the cavity region.Type: GrantFiled: April 9, 2004Date of Patent: May 27, 2008Assignee: California Institute of TechnologyInventors: Yu-Chong Tai, Matthieu Liger, Ming C. Wu, Jui-che Tsai
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Patent number: 7085122Abstract: A MEMS tunable capacitor with angular vertical comb-drive (AVC) actuators is described where high capacitances and a wide continuous tuning range is achieved in a compact space. The comb fingers rotate through a small vertical angle which allows a wider tuning range than in conventional lateral comb drive devices. Fabrication of the device is straightforward, and involves a single deep reactive ion etching step followed by release and out-of-plane assembly of the angular combs.Type: GrantFiled: May 21, 2004Date of Patent: August 1, 2006Assignee: The Regents of the University of CaliforniaInventors: Ming C. Wu, Hung D. Nguyen, Doo-Young Hah, Pamela R. Patterson
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Patent number: 6958132Abstract: The invention is related to methods and apparatus that manipulate droplets in a microfluidic environment. Advantageously, embodiments of the invention manipulate droplets by controlling the electro-wetting characteristics of a surface with light, thereby inducing a gradient in the surface tension of a droplet. The gradient in the surface tension propels the droplet by capillary force. A variety of operations, such as transporting, joining, cutting, and creating can be performed. Advantageously, embodiments of the invention obviate the need to create a relatively large and complex control electrode array. A plurality of photoconductive cells or a layer of a photoconductive material selectively couples an electrode carrying an electrical bias to otherwise floating conductive cells in response to a beam of light. The electrical bias applied to the conductive cell generates a localized electric field, which can change the contact angle of the droplet, thereby permitting the droplet to be propelled.Type: GrantFiled: May 31, 2002Date of Patent: October 25, 2005Assignee: The Regents of the University of CaliforniaInventors: Pei Yu Chiou, Ming C. Wu
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Publication number: 20030224528Abstract: The invention is related to methods and apparatus that manipulate droplets in a microfluidic environment. Advantageously, embodiments of the invention manipulate droplets by controlling the electro-wetting characteristics of a surface with light, thereby inducing a gradient in the surface tension of a droplet. The gradient in the surface tension propels the droplet by capillary force. A variety of operations, such as transporting, joining, cutting, and creating can be performed. Advantageously, embodiments of the invention obviate the need to create a relatively large and complex control electrode array. A plurality of photoconductive cells or a layer of a photoconductive material selectively couples an electrode carrying an electrical bias to otherwise floating conductive cells in response to a beam of light. The electrical bias applied to the conductive cell generates a localized electric field, which can change the contact angle of the droplet, thereby permitting the droplet to be propelled.Type: ApplicationFiled: May 31, 2002Publication date: December 4, 2003Inventors: Pei Yu Chiou, Ming C. Wu
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Patent number: 6526198Abstract: In at least one embodiment, a MEMS optomechanical switch in accordance with the present invention includes a substrate, a signal source capable of transmitting a radiation signal, an electrode coupled to the substrate, and a micromachined plate rotatably coupled to the substrate about a pivot axis. The switch further includes a micromirror having an orientated reflective surface, mounted to the micromachined plate and an electrical source coupled to at least one of the electrode and the micromachined plate.Type: GrantFiled: January 17, 2002Date of Patent: February 25, 2003Assignee: OMM, Inc.Inventors: Ming C. Wu, Li Fan, Anis Husain
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Patent number: 6449301Abstract: External cavity semiconductor lasers using a saturable Bragg reflector as an external reflector are mode locked and produce output pulses of 1.9 ps from a semiconductor lasers without dispersion compensation. By coupling the output to a standard single mode fiber with a length of 35 m to compensate the linear chirp, the mode-locked pulse duration as short as 880 fs is achieved.Type: GrantFiled: June 22, 1999Date of Patent: September 10, 2002Assignee: The Regents of the University of CaliforniaInventors: Ming C. Wu, Ji-Lin Shen
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Patent number: 5646928Abstract: A monolithically integrated optical disk pickup head is comprised of three-dimensional collimating focusing lenses, a beam splitter and 45-degree reflectors that define an optical axis in free-space using surface micromachining technology to fabricate hinged vertical optical structures.Type: GrantFiled: June 22, 1995Date of Patent: July 8, 1997Assignee: The Regents of the University of CaliforniaInventors: Ming C. Wu, Lih-Yuan Lin
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Patent number: 5028445Abstract: The forming of simulated crustacean meat includes the steps of:a) forming a mixture D of the following components:1) surimi paste A2) pieces B of cooked surimi paste3) pieces C of a mixture of surimi paste, starch, protein, and konnyaku powder, the mixture having been gelled, frozen, thawed and then shredded, andb) cooking the mixture D in a crustacean-shaped mold cavity to set.Type: GrantFiled: May 8, 1989Date of Patent: July 2, 1991Assignee: Jac Creative Foods, Inc.Inventors: Ming C. Wu, Teisuke Suzuki
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Patent number: 4994366Abstract: The preparation of a shrimp-like product, which includes: providing a surimi paste; providing an aqueous mixture B in paste form which contains both glucomannan and carrageenan, and protein and starch; forming a mixture C which contains the paste and the aqueous mixture B; extruding the mixture C to form an extrudate, cutting the extrudate to form pieces; and contacting the pieces with hot water for a time between 1 and 30 minutes to cook the pieces, and thereafter with cold water to thereby form gelled product pieces.Type: GrantFiled: November 7, 1989Date of Patent: February 19, 1991Assignee: JAC Creative Foods, Inc.Inventor: Ming C. Wu
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Patent number: D360221Type: GrantFiled: June 24, 1994Date of Patent: July 11, 1995Inventor: Ming C. Wu