Abstract: The present invention discloses an asymmetric virtual-ground single-ended SRAM and a system thereof, wherein a first inverter is coupled to a high potential and a virtual ground, and wherein the first inverter and a second inverter form a latch loop, and wherein a third inverter is electrically connected with the second inverter, and wherein the third inverter and the second inverter are jointly coupled to the high potential and a ground. A write word line and a read word line control an access transistor and a pass transistor to undertake writing and reading of signals. A plurality of asymmetric virtual-ground single-ended SRAMs forms a memory system.