Patents by Inventor Ming Hsieh

Ming Hsieh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180162933
    Abstract: The subject invention relates to isolated proteins, particularly monoclonal antibodies, which bind and neutralize RGM A protein. Specifically, these antibodies have the ability to inhibit the binding of RGM A to its receptor and/or coreceptors. These antibodies or portions thereof of the invention are useful for detecting RGM A and for inhibiting RGM A activity, for example in a human suffering from a disorder including but nor limited to multiple sclerosis, mammalian brain trauma, spinal cord injury, stroke, neurodegenerative diseases, and schizophrenia.
    Type: Application
    Filed: December 5, 2017
    Publication date: June 14, 2018
    Inventors: Bernhard K. Mueller, Martin Schmidt, Eve Barlow, Mary Leddy, Chung-Ming Hsieh, Philip Bardwell
  • Publication number: 20180159343
    Abstract: An integrated uninterruptible power supply (UPS) includes a UPS main board coupled with a controller and a battery pack. The UPS main board includes an AC (alternating current) input, a noise filtering surge protecting high voltage circuit breaker, a high power factor correction rectifier, a DC (direct current) bus, an inverter, a high power charger, a first battery contact, a second battery contact, a DC/DC convertor and an AC output. The present disclosure integrates a noise filter, a surge protector and a high voltage circuit breaker, and integrates a high power charger in the same circuit board. Therefore, the present disclosure lowers the material and production costs of UPS products, and decreases the circuit board size. In addition, the present disclosure decreases the total harmonic distortion, the ripples of input current, and the crosstalk between circuits, and increases the input power factor, the charging efficiency and the battery life.
    Type: Application
    Filed: February 2, 2017
    Publication date: June 7, 2018
    Inventors: MING-HSIEN CHEN, JUOR-MING HSIEH
  • Publication number: 20180143740
    Abstract: A cover window is provided and includes a substrate and a coating layer. The substrate has a thickness of 60 to 120 ?m. The substrate has a Re of 6000 to 12000. The coating layer is coated on the substrate. The cover window has a first direction and a second direction. The first direction is a machine direction of the cover window. The second direction is perpendicular to the first direction. A tensile stress of 50 to 130 MPa is exerted in the first direction. A tensile stress of 140 to 300 MPa is exerted in the second direction. Since the substrate has a Re of 6000 to 12000, a penetrating ray of an incident ray is uniformly distributed on a visible region of the cover window, so as to reduce the phase difference between reflected rays, reduce rainbow patterns, and enhance visibility under a polarizer.
    Type: Application
    Filed: May 18, 2017
    Publication date: May 24, 2018
    Inventors: Chun-Jen CHEN, Nan-Tsun Kuo, Chia-Ming Hsieh, Tzu-Hsiang Lin
  • Patent number: 9977722
    Abstract: The present disclosure illustrates a cabinet type on-site monitoring device, which comprises a monitoring module and a positioning mechanism, and monitoring method thereof. The monitoring module can automatically detect an electric apparatus installed inside a cabinet for monitoring, and a main body can be combined on a casing structure, or the casing structure is movably pivoted on a cabinet door by using a positioning component and hang holes or a through hole on a support. Manager can watch the monitoring device via window or directly to look over current operation status of respective electric apparatus without opening the cabinet door. A sound or visible warning action is performed when the monitoring module automatically detects and gets real-time status data of any of electric apparatus exceeding a setting normal range, so as to increase convenience and flexibility of on-site immediate management, and keep the electric apparatus operate more efficiently.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: May 22, 2018
    Assignee: CYBERPOWER SYSTEMS, INC.
    Inventors: Hung-Ming Hsieh, Hung-Chun Chien, Yung-Hao Peng
  • Publication number: 20180125999
    Abstract: The invention relates to anti-epidermal growth factor (EGFR) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
    Type: Application
    Filed: November 9, 2017
    Publication date: May 10, 2018
    Inventors: EDWARD B. REILLY, ANDREW C. PHILLIPS, LORENZO BENATUIL, FRITZ G. BUCHANAN, JONATHAN A. MEULBROEK, CHUNG-MING HSIEH, JENNIFER PEREZ
  • Publication number: 20180102767
    Abstract: Illustrated are a switched-capacitor DC-DC convertor and a control method thereof. The switched-capacitor DC-DC convertor includes a switched-capacitor circuit, a latched comparator and a clock generating module. The switched-capacitor circuit converts an input voltage into an output voltage through a phase switching operation. The latched comparator receives a clock signal, and compares the output voltage and a reference voltage according to the clock signal, to generate the control signal, which triggers a phase switching operation of the switched-capacitor circuit. The clock generating module generates the clock signal, and adjusts a frequency of the clock signal according to variation of the control signal.
    Type: Application
    Filed: February 1, 2017
    Publication date: April 12, 2018
    Inventors: Chung-Ming HSIEH, WEI-CHAN HSU
  • Patent number: 9915665
    Abstract: System and methods are disclosed for identifying and isolating antibodies with specific affinity with an antigen of interest. Multiple DNA libraries encoding antibodies or their fragments are designed such that the encoded antibodies from different libraries are tagged differently. These libraries may be transformed into yeast cells. The variants of the antibodies are displayed on the surface of the yeast cells and flow cytometry may be used to sort the cells based on antigen affinity and the different tags on the antibodies. By allowing multiple libraries to be screened simultaneously, the disclosed methods help improve the efficiency of affinity.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: March 13, 2018
    Assignee: ABBVIE INC.
    Inventors: Lorenzo Benatuil, Jennifer Perez, Chung-Ming Hsieh
  • Publication number: 20180061727
    Abstract: A semiconductor device package comprises an adhesive layer, a die on the adhesive layer, a first encapsulation layer encapsulating the die and the adhesive layer, and a second encapsulation layer adjacent to the first encapsulation layer and the adhesive layer. The second encapsulation layer has a first surface and a second surface different from the first surface. A contact angle of the first surface of the second encapsulation layer is different from a contact angle of the second surface of the second encapsulation layer.
    Type: Application
    Filed: August 11, 2017
    Publication date: March 1, 2018
    Applicant: Advanced Semiconductor Engineering, Inc.
    Inventors: Li-Hao LYU, Chieh-Ju TSAI, Yu-Kai LIN, Wei-Ming HSIEH, Yu-Pin TSAI, Man-Wen TSENG, Yu-Ting LU
  • Publication number: 20180061813
    Abstract: A semiconductor device package including a first encapsulation layer, a redistribution layer disposed on the first encapsulation layer, a first die disposed on the redistribution layer, a second encapsulation layer covering the first die and the redistribution layer, and an electrical connection terminal electrically connected to the redistribution layer. The first encapsulation layer has a first surface and a second surface different from the first surface. The first encapsulation layer surrounds a portion of the electrical connection terminal and exposes the electrical connection terminal.
    Type: Application
    Filed: August 11, 2017
    Publication date: March 1, 2018
    Applicant: Advanced Semiconductor Engineering, Inc.
    Inventors: Wei-Ming HSIEH, Yu-Pin TSAI, Man-Wen TSENG, Li-Hao LYU
  • Patent number: 9898021
    Abstract: The present disclosure illustrates a dual-mode regulator circuit comprising: a first output terminal; a second output terminal; a switching regulator circuit coupled to the first output terminal and comprising a first transistor coupled between the first output terminal and ground; a linear regulator circuit coupled to the second output terminal and comprising a second transistor coupled between the second output terminal and a power source; a detection circuit configured to turn on the first transistor in order to connect the first output terminal to ground, turn on the second transistor in order to connect the second output terminal to the power source, and then generate a detection signal indicating whether an inductor is connected between the first and second output terminals; and a logic circuit configured to activate the switching regulator circuit or the linear regulator circuit according to the detection signal.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: February 20, 2018
    Assignee: Nuvoton Technology Corporation
    Inventor: Chung-Ming Hsieh
  • Publication number: 20180048226
    Abstract: A DC-DC power converter circuit includes a switched-capacitor circuit, an error amplifier, a latched comparator and a switching controller. The error amplifier adjusts an error amplification signal of the error amplifier in response to an output voltage of the switched-capacitor circuit and a reference voltage. The error amplification signal is then fed to the latched comparator as a comparison reference, resulting in the DC-DC power converter circuit being able to more precisely maintain the output voltage within a predetermined range.
    Type: Application
    Filed: June 8, 2017
    Publication date: February 15, 2018
    Inventors: CHUNG-MING HSIEH, WEI-CHAN HSU
  • Patent number: 9888616
    Abstract: The instant disclosure relates to a chassis structure for industrial uninterruptible power supply system including: a chassis having a frame and a front side panel, left side panel, right side panel, rear side panel and top panel installed on the frame; the chassis has a plurality of spacer on the bottom thereof for lifting the chassis from the ground for a distance to forming a gas-intake space; a plurality of protective plates disposed around the gas-intake space, each protective plate has a plurality of gas-intake hole; a bottom plate structure disposed between the bottom of the chassis and the gas-intake space and has at least a gas-intake gap; at least a venting hole disposed on the top panel of the chassis, each venting hole has at least an exhaust fan for outputting a gas from the chassis.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: February 6, 2018
    Assignee: VOLTRONIC POWER TECHNOLOGY CORP.
    Inventors: Tung-Chen Yu, Xiao-Bo Wan, Juor-Ming Hsieh
  • Patent number: 9871405
    Abstract: Disclosed is a voltage regulating circuit, comprising an input end, an output end, a protecting switch, a first switch, a second switch, a third switch, a first coil and a second coil. The third switch comprises a first terminal and a second terminal. The second terminal of the third switch is connected to a third terminal of the first switch. One end of the first coil is connected to a second terminal of the first switch, and the other end of the first coil is connected to a third terminal of the first switch. One end of the second coil is connected to a first terminal of the third switch, and the other end of the second coil is connected to a fourth terminal of the protecting switch. Different connections between switches and the transformer provide various voltage adjustments to reduce power loss and to increase power transformation efficiency.
    Type: Grant
    Filed: March 8, 2016
    Date of Patent: January 16, 2018
    Assignee: VOLTRONIC POWER TECHNOLOGY CORP.
    Inventors: Wei-Jun Guo, Juor-Ming Hsieh
  • Patent number: 9827330
    Abstract: The invention relates to anti-epidermal growth factor (EGFR) antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: November 28, 2017
    Assignee: Abbvie Inc.
    Inventors: Edward B. Reilly, Andrew C. Phillips, Lorenzo Benatuil, Chung-Ming Hsieh, Jennifer Perez
  • Patent number: 9803009
    Abstract: Isolated binding proteins, e.g., antibodies or antigen binding portions thereof, which bind to tumor necrosis factor-alpha (TNF-?), e.g., human TNF-?, and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: October 31, 2017
    Assignee: AbbVie Inc.
    Inventors: Chung-Ming Hsieh, Lorenzo Benatuil, Yuliya Kutskova, John Memmott, Jennifer Perez, Suju Zhong, Carrie Goodreau, Anca Clabbers
  • Patent number: D795713
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: August 29, 2017
    Assignee: VivaLnk, Inc.
    Inventors: Matthew Griffin Pugmire, Gad Amit, Jinwoo Kim, Scott Michael Thibeault, Byron Ben Ming Hsieh
  • Patent number: D795714
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: August 29, 2017
    Assignee: VivaLnk, Inc.
    Inventors: Matthew Griffin Pugmire, Gad Amit, Jinwoo Kim, Scott Michael Thibeault, Byron Ben Ming Hsieh
  • Patent number: D802452
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: November 14, 2017
    Assignee: Fitbit, Inc.
    Inventors: Brian Dennis Paschke, Jonah Avram Becker, Susan Elizabeth McKinney, Ellise Noel Smolenyak, Byron Ben-Ming Hsieh, Anthony Joseph Smith, Gad Amit
  • Patent number: D802454
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: November 14, 2017
    Assignee: Fitbit, Inc.
    Inventors: Brian Dennis Paschke, Jonah Avram Becker, Susan Elizabeth McKinney, Ellise Noel Smolenyak, Byron Ben-Ming Hsieh, Anthony Joseph Smith, Gad Amit
  • Patent number: D803077
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: November 21, 2017
    Assignee: Fitbit, Inc.
    Inventors: Brian Dennis Paschke, Jonah Avram Becker, Susan Elizabeth McKinney, Ellise Noel Smolenyak, Byron Ben-Ming Hsieh, Anthony Joseph Smith, Gad Amit