Abstract: The present disclosure provides bispecific binding proteins and fragments thereof which bind to human CD137 and a tumor associated antigen (e.g., Claudin-6, Claudin 18.2, or Nectin-4), to polynucleotide sequences encoding these antibodies and to cells producing them. The disclosure further relates to therapeutic compositions comprising these antibodies, and to methods of their use for cancer detection, prognosis and antibody-based immunotherapy.

Abstract: The present disclosure provides a direct current (DC) transformer error detection apparatus for a pulsating harmonic signal, including a DC and pulsating harmonic current output module and an external detected input module, where the DC and pulsating harmonic current output module outputs a DC and a DC superimposed pulsating harmonic current to an internal sampling circuit and a self-calibrated standard resistor array; and the internal sampling circuit converts the input DC and the input DC superimposed pulsating harmonic current into a voltage signal, and sends the voltage signal to an analog-to-digital (AD) sampling and measurement component through a front-end conditioning circuit and a detected input channel. The DC transformer error detection apparatus can complete self-calibration for measurement of the DC and the pulsating harmonic signal on a test site.

Abstract: The present disclosure provides a collaborative robot arm and a joint module. The joint module includes a housing, a driving assembly, and a multi-turn absolute encoder. The joint module detects the angular position of the output shaft and records a number of rotating revolutions of the output shaft only by means of the multi-turn absolute encoder. The multi-turn absolute encoder includes a base, a bearing, a rotating shaft, an encoding disk, and a circuit board, the encoding disk is rotatably connected with the base by the rotating shaft and the bearing, the circuit board is fixedly connected with the base, and the reading head on the circuit board detects the angular position of the output shaft cooperatively with the encoding disk, making the multi-turn absolute encoder be an integrated structure. The base and the rotating shaft are detachably connected with the housing and the output shaft respectively.

Abstract: A system uses a machine learning model trained using multitask learning for processing audio signals of different types. The system may be used in a device such as a headset, smart glasses, or a smart watch, and may be used to make predictions based on different types of audio signals, for example, for classifying acoustic events based on audio signal or for keyword spotting to detect wake words. The use of a single machine learning model for analyzing different types of audio signals improves storage efficiency as well as energy efficiency of devices compared to systems that use a different machine learning model for processing each type of audio signal.

Abstract: A computer program product, a method and a baseboard management controller for performing the operations of computer program product or method. The operations include identifying a current utilization level of the processor of the baseboard management controller, obtaining hardware performance data for hardware devices installed in a server that includes the baseboard management controller, running an application program that performs hardware failure prediction, and controlling an amount of the hardware performance data that is used by the application program to perform the hardware failure prediction, wherein the amount of the hardware performance data is controlled as a function of the current utilization level of the processor.

Abstract: A baseboard management controller (BMC) may obtain hardware performance data for hardware devices installed in a server that includes the BMC, provide the hardware performance data to a smart network interface controller (Smart NIC) in the server, and receive from the Smart NIC a hardware failure alert that identifies a hardware device predicted to experience a failure based on the hardware performance data. Optionally, the BMC may access a container stored in firmware of the BMC, wherein the container includes a software application such as an artificial intelligence engine trained for hardware failure prediction. The BMC may copy the container to the Smart NIC for running the software application to analyze the hardware performance data and generate a hardware failure alert. The BMC may receive the alert and output a user notification identifying the hardware device that is subject to the alert.

Abstract: Methods and systems of tool-free adjustment of torque used to maintain the viewing angle of a display stand are performed. In one exemplary embodiment, a method is performed by a device having a platform hingedly coupled to a base. A bar rotatably supported by the base includes a left-hand threaded portion, a right-hand threaded portion, and a grip configured to enable simultaneous rotation of both threaded portions. A first nut is in threaded engagement with the left-hand threaded portion, and a second nut is in threaded engagement with the right-hand threaded portion. A first spring is coupled to the first nut and the platform, and a second spring is coupled to the second nut and the platform. When the bar is rotated via the grip, the first and second nuts move in opposing directions to enable simultaneous tension adjustment of the first and second springs.

Abstract: A fabrication method for a steel thin-walled tailor-welded part and a hot-stamped part prepared by using the tailored welded part, the method comprising: using steel plates (10, 10, 20) to be welded which have an aluminum or aluminum alloy coating (12, 12?, 22, 22?) is used; by means of adjusting the composition of a shielding gas (50) and the composition of a welding wire (30) during a welding process, in combination with the control of the welding speed and wire-feeding speed, controlling the content of free aluminum in a weld seam to be 0.1 to 4.0 wt. %, which prevents the production of iron-aluminum intermetallic compounds in the weld seam during a tailor welding process while ensuring that an appropriate amount of ferrite which is distributed in a dispersed manner is produced in the weld seam. The weld seam structure of the obtained tailor-welded part is +1 to 15 vol. % martensite, +0 to 5 vol. % ferrite which is distributed in a dispersed manner, and the remainder is austenite.

Abstract: A method, computer system, and a computer program product are provided for a restoring missing content to a user that was absent during a portion of a live event. The process will identify the absence period and that is being participated by a user and obtains extracted information relating to the user that was previously gathered from a variety of sources including past user interactions and a user profile. This information is further analyzed and prioritized according to user interest priority determined by the extracted information. This information is categorized into a first set of domains. Information provided during the absence of the user will also be captured and categorized into a second set of domain categories. An intersection between the first and second set of domain categories will be found and prioritized by user interest. This will be presented to the user upon user's return.

Abstract: Apparatuses, methods, systems, and program products are disclosed for dynamic baseboard management controller memory use. A method includes determining, by use of a processor, presence of main memory of a computing device, in response to determining that the main memory is not present in the computing device, preparing at least a portion of a memory device of a baseboard management controller for use by the processor, and making the at least a portion of the memory device of the BMC available to the processor.

Abstract: The present disclosure provides for antibodies and antigen-binding fragments thereof that bind to human CD3, a pharmaceutical composition comprising said antibody or antigen-binding fragments thereof, and use of the antibody or antigen-binding fragments thereof or the composition for treating a disease, such as cancer.

Abstract: The present disclosure provides for multi-specific antibodies and antigen-binding fragments thereof that bind to human CLDN6 and CD3, a pharmaceutical composition comprising said antibody or antigen-binding fragments thereof, and use of the multi-specific antibody or antigen-binding fragments thereof or the composition for treating a disease, such as cancer.

Abstract: The present disclosure provides for antibodies and antigen-binding fragments thereof that bind to human CLDN6, a pharmaceutical composition comprising said antibody or antigen-binding fragments thereof, and use of the antibody or antigen-binding fragments thereof or the composition for treating a disease, such as cancer.

Abstract: A semiconductor device includes a transistor, a semiconductor layer, an active region and a conductive layer. The active region is in the semiconductor layer. The conductive layer is configured to maintain a channel in the active region when the transistor is triggered to be conducted.

Abstract: Methods and systems of tool-free adjustment of torque used to maintain the viewing angle of a display stand are performed. In one exemplary embodiment, a method is performed by a device having a platform hingedly coupled to a base. A bar rotatably supported by the base includes a left-hand threaded portion, a right-hand threaded portion, and a grip configured to enable simultaneous rotation of both threaded portions. A first nut is in threaded engagement with the left-hand threaded portion, and a second nut is in threaded engagement with the right-hand threaded portion. A first spring is coupled to the first nut and the platform, and a second spring is coupled to the second nut and the platform. When the bar is rotated via the grip, the first and second nuts move in opposing directions to enable simultaneous tension adjustment of the first and second springs.

Abstract: A firmware protection method includes monitoring an access request to a storage device and obtaining access request data. The storage device is configured to store firmware. The method further includes, in response to the access request data, when determining that the access request is a denial-of-service (DOS) attack, performing write protection on a first region of the storage device, maintaining the power supply to the storage device, and allowing the storage device to be accessible by the firmware.

Abstract: The invention provides compositions and methods for treating diseases associated with expression of CD20 or CD22. The invention also relates to chimeric antigen receptor (CAR) specific to CD20 or CD22, vectors encoding the same, and recombinant T or natural killer (NK) cells comprising the CD20 CAR or CD22 CAR. The invention also includes methods of administering a genetically modified T cell or NK cell expressing a CAR that comprises a CD20 or CD22 binding domain.

Abstract: A circuit package may comprise (1) a substrate, (2) at least one radio frequency (RF) circuit disposed on the substrate, and (3) a plurality of screw holes that are incorporated into the substrate and configured to support mounting the substrate to an enclosure, wherein at least one of the screw holes is further configured to provide at least one supplemental function in connection with the RF circuit. Various other apparatuses, systems, and methods are also disclosed.

Abstract: A replacement node replaces a failed node and a baseboard management controller (BMC) for the replacement node generates a nonce code that is accessible to an authenticated user. An edge management node receives the nonce code from the user and sends a maintenance token to a BMC of a peer node in an edge cluster, wherein the peer nodes BMCs within the cluster are in a BMC federation that included the failed node BMC and have access to a BMC configuration for the failed node. The management node sends the token and the nonce code to the replacement node BMC for authentication of the token. The peer node BMC sends the token received from the management node to the replacement node BMC for authentication of the peer node BMC. The authenticated peer node BMC may then deploy the BMC configuration to the replacement node BMC.