Abstract: The present disclosure provides methods and kits for diagnosing and assessing SAGE1-positive disorders, and compositions and methods for treating SAGE1-positive disorders. The present disclosure further provides SAGE1 complexes and methods and composition for inhibiting SAGE1 complexes and treating SAGE1-positive disorders.

Abstract: The present invention discloses a division method and system for distributed renewable-energy electricity generation clusters, where the method includes: obtaining electric power consumption-absorption data of the electricity-generation clusters; extracting and analyzing the absorbed electricity quantities of the corresponding target single electricity generators or the consumed electricity quantities of the corresponding target energy consumption nodes; constructing and determining consumption-absorption matching groups for a plurality of electricity generator sets and energy consumption districts according to distances from the target single electricity generators to the target energy consumption nodes, and executing division for the electricity-generation clusters. According to the present invention, energy waste can be avoided, and then management efficiency is increased.

Abstract: Disclosed in the present disclosure is an underground cable path tester, in which a first signal processing device is connected to a data port of a primary unit central control module, and a second signal processing device is connected to an output port of the first signal processing device; regarding the first signal processing device, data ports of a signal receiving module, a signal amplifying module, a phase-locked loop module, and a secondary unit central control module are sequentially connected; and regarding the second signal processing device, a probe, a filter module, an amplifier module, and an alarm module are sequentially connected.

Abstract: The present disclosure relates to the technical field of cable locating and pairing. Disclosed are a circuit for implementing cable locating and pairing applied to a cable maintenance equipment and a cable maintenance equipment. The circuit for implementing cable locating and pairing includes a cable locating signal processing circuit and a cable pairing signal transmission circuit. The cable locating signal processing circuit includes a cable locating signal buffer circuit and a cable locating signal transmission circuit. A first terminal of the cable pairing signal transmission circuit is electrically connected to a cable pairing control terminal of the first main control circuit and is configured to be grounded. It is evident that the circuit for implementing cable locating and pairing in the present disclosure is simple in structure and can effectively reduce power consumption of cable locating and pairing.

Abstract: The present invention discloses a method and a system for controlling an overvoltage in a photovoltaic court based on a floating neutral voltage, including: acquiring, by a controller, a voltage U of the photovoltaic court and a voltage U0 of a transformer neutral point; comparing acquired voltage data with a set threshold; generating control instructions of offsetting and compensation according to a comparison result; and receiving the instructions by a neutral voltage regulator, and controlling a voltage. The present invention introduces a floating neutral line between a photovoltaic power supply and a grid-connected transformer neutral point, and arranges a neutral voltage regulator on the floating neutral line. By adjusting its direction and size, the neutral voltage regulator can adapt to the voltage problem of the court in different states. Meanwhile, by adjusting the voltage on the grid-connected transformer neutral point side, the voltage of the grid-connected transformer neutral point is zero.

Abstract: Systems and methods are provided for performing customizable machine prediction using an extensible software tool. A specification including features of a trained machine learning model can be received and an interface for the trained machine learning model can be generated. The trained machine learning model can be loaded using the interface, the loaded machine learning model including a binary file configured to receive data as input and generate prediction data as output. Predictions can be generated using observed data that is stored according to a multidimensional data model, wherein a portion of the observed data is input to the loaded machine learning model to generate first data predictions, and a portion of the observed data is used by a generic forecast model to generate second data predictions. The first and second data predictions can be displayed in a user interface configured to display intersections of the multidimensional data model.

Abstract: Various approaches can be used to interrogate a surface such as a surface of a layered semiconductor structure on a semiconductor wafer. Certain approaches employ Second Harmonic Generation while other utilize four wave-mixing or multi-wave mixing. Corona discharge may be applied to the sample to provide additional information. Some approaches involve determining current flow from a sample illuminated with radiation.

Abstract: The present invention discloses coated ultrahigh-strength steel with low spot welding crack sensitivity, comprising a steel substrate and a zinc-containing coating on the surface of the steel substrate. The steel substrate contains Fe and inevitable impurity elements. The steel substrate further contains the following chemical elements in percentage by mass: 0.10-0.30% of C, 0.30-0.90% of Si, 1.00-2.20% of Mn, 0.001-0.003% of B, and 0.30-1.00% of Al. Correspondingly, the present invention further discloses a manufacturing method for the coated ultrahigh-strength steel. The coated ultrahigh-strength steel in the present invention can be effectively prepared by using the manufacturing method, the final yield strength is 600-850 MPa, the tensile strength is 980-1150 MPa, the uniform elongation is not less than 13%, and the elongation at break is not less than 15%.

Abstract: The invention provides compositions and methods for treating diseases associated with expression of CD20 or CD22. The invention also relates to chimeric antigen receptor (CAR) specific to CD20 or CD22, vectors encoding the same, and recombinant T or natural killer (NK) cells comprising the CD20 CAR or CD22 CAR. The invention also includes methods of administering a genetically modified T cell or NK cell expressing a CAR that comprises a CD20 or CD22 binding domain.

Abstract: A method for replacing at least one hardware assembly of a data processing apparatus includes managing, by a system management software, the data processing apparatus with a service processor and a plurality of hardware assemblies, obtaining, by the system management software, first system configuration data, first system vital product data (SVPD), and first server identity data of the data processing apparatus from the service processor or through the service processor, obtaining, by the system management software, second SVD and second server identity data of the data processing apparatus from the service processor or through the service processor, comparing, by the system management software, the first server identity data with the second server identity data, and configuring, by the system management software, the data processing apparatus based on the first system configuration data and the first SVPD according to a comparison result.

Abstract: In a device operable for determining a state of charge (SOC) of a battery, an acquisition circuit is configured to acquire state parameters of the battery. A processing circuit is configured to: determine a first SOC of the battery by using an AI model based on the state parameters; determine a second SOC of the battery by using a stored lookup table, where the lookup table stores at least a portion of the state parameters and an SOC of the battery in association with each other; and determine a third SOC of the battery by calculating a weighted average of the first SOC of the battery and the second SOC of the battery based on weights of the first SOC of the battery and the second SOC of the battery, where the third SOC represents the SOC of the battery.

Abstract: A multifunctional line finder for miniature circuit breaker includes an emitter and a receiver, in which the emitter includes an emitting module for emitting line-finding signal and an LNG line-order detection module, the emitting module includes a main control unit, a strong electricity line-finding emitting unit, and a network line-finding emitting unit, the receiver includes a receiving module, an operational amplifier module, a signal processing module, and an audio drive module, a line-finding signal output end of the emitting module is connected to a line-finding signal input end of the receiving module, a signal detecting output end of the LNG line-order detection module is connected to a signal detecting input end of the receiving module, a signal receiving output end of the receiving module is connected to a signal receiving input end of the operational amplifier module.

Abstract: The present invention relates to a process for producing a population of cells which comprises mature atrial cardiomyocytes. The process comprises the step of treating iPS cells according to a treatment regimen which comprises contacting the iPS cells with Gremlin2 and retinoic acid, such that at least a portion of the iPS cells differentiate into mature atrial cardiomyocytes.

Abstract: The present disclosure provides monoclonal and recombinant anti-CDH17 antibodies (including CDH17 biparatopic and CDH17xCD3 bispecific antibodies and CDH17-binding fragments. Such antibodies and binding fragments are useful for the treatment of cancer, cither alone or in combination with other agents.

Abstract: The present disclosure relates to the technical field of cable testing, disclosing a cable testing device for running lights wire pairing and tracing and a cable tester. By utilizing a main test circuit and a secondary test circuit, the device/tester jointly implements running lights wire pairing and tracing functions for a cable to be test: By implementing, at a first data processing module in the main test circuit, target signal generation and transmission down including a pairing signal and a tracing signal, the first pairing and tracing module cooperates with the first running lights module to respond to the target signal, while the second pairing and tracing module in the secondary test circuit cooperates with the second running lights module to respond to the target signal.

Abstract: The disclosure provides a method for treating a subject afflicted with a tumor comprising administering to the subject a therapeutically effective amount of an anti-PD-1 antibody or antigen-binding portion thereof or an anti-PD-L1 antibody or antigen-binding portion thereof, wherein the subject is identified as having a low stromal gene signature score. In some aspects, the low stromal gene signature score is determined by measuring the expression of a panel of stromal genes in a tumor sample obtained from the subject, wherein the stromal gene panel comprises at least four genes selected from CDH1, CDH2, MMP1, MMP2, ITGA1, ITGA2, ITGA3, ITGA5, ITGA7, ITGA11, TGFB1, and TGFB1; at least four genes selected from TGFB1, TGFBR2, ACTA2, COL4A1, TAGLN, SH3PXD2A, TWIST1, ZEB1, and ZEB2; or MMP2 and MMP9.

Abstract: The line-alignment indicator circuit includes at least one set of LED indicators, each set of LED indicators comprising an LED lamp, a diode, a filter capacitor respectively, wherein the LED lamp and the diode are connected in reverse parallel, the filter capacitor is connected in parallel to the LED lamp, and a capacitance of the filter capacitor is 100 nf-10 ?f. In the present disclosure, each line-alignment indicator is connected in parallel with a capacitor with a capacitance of 100 nf-10 ?f. Due to the characteristic of the capacitor blocking DC but passing AC, it filters out the influence of IF line-finding signal, and does not form voltage difference on the line indicator causing disorderly flashing of the line indicator, so as to achieve the compatibility of the two functions of line finding and line alignment, and to eliminate the interference of the line-finding signal on the line-alignment indicator.

Abstract: A method for creating an edge server connected to a cloud server with a tunnel connection includes creating a tunnel connection between a port of an edge server and a port on a cloud server. The cloud server is unable to establish a communication link with the edge server independent of the tunnel connection. The method includes initiating a proxy on the edge server. The cloud server initiates a proxy on the cloud server after creation of the tunnel connection. Each proxy is configured to receive a message from a port and to transmit, over the tunnel connection, a modified message with a port number and the message. The port number is for a destination and each proxy is configured to receive a modified message over the tunnel connection and to transmit the message of the modified message to the port identified by the port number in the modified message.

Abstract: A communications system may include first and second electronic devices. The first device may transmit an ultra-wideband (UWB) signal to the second device. The UWB signal may include pulses that represent a ranging frame. The pulses may include a series of pulses representing a physical layer (PHY) payload of the ranging frame. The second device may estimate a range to the first device and/or a location of the first device based on a correlation of the series of pulses representing the PHY payload of the ranging frame. The first device may apply a coding scheme to the PHY payload that reduces, or minimizes, a bit error rate of the correlation at the second device, may apply a cyclic redundancy check, may transmit the PHY payload using a spreading factor greater than one, and/or may apply encryption to the PHY payload for integrity check purposes.

Abstract: A method for estimating battery capacity of a battery, includes: sampling a series of voltages across a sensor resistor coupled to the battery when a current flows through the sensor resistor under conditions of default time and default temperature, and recording the voltages as sample voltages; calculating average filtering voltages by filtering white noise in the sample voltages; calculating median filtering voltages by removing impulse noise in the average filtering voltages; detecting data scope of the median filtering voltages in the data characteristic filed; calculating low-pass filtering voltages by using a low-pass filter formula according to the median filtering voltages domain in the data characteristic filed; and estimating the battery capacity of the battery according to the low-pass filtering voltages.