Patents by Inventor Ming Lei

Ming Lei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12679890
    Abstract: Antibodies that specifically bind to the human tight junction molecule CLDN18.2 and have functional properties that make them suitable for use in antibody-based immunotherapies of a disease associated with aberrant expression of CLDN18.2 are disclosed.
    Type: Grant
    Filed: June 22, 2022
    Date of Patent: July 14, 2026
    Assignee: CSPC Megalith Biopharmaceutical Co., Ltd.
    Inventors: Han Li, Ming Lei, Yi Pei, Haichun Huang
  • Publication number: 20260196010
    Abstract: Methods, systems, and apparatuses are provided to track features across multiple images for use in various systems. For example, a computing device receives at least a first image and a second image captured by a camera, and detects a feature within each of the first image and the second image. The feature is located at a first feature position within the first image and at a second feature position within the second image. The computing device also receives a first sensor pose of the sensor used to capture the first image and a second sensor pose of the sensor used to capture the second image. The computing device determines a portion of third image based on the first sensor pose, the second sensor pose, the first feature position, and the second feature position. The computing device then generates feature detection data characterizing whether the feature is detected.
    Type: Application
    Filed: January 12, 2023
    Publication date: July 9, 2026
    Inventors: Ming LEI, Bo HU
  • Publication number: 20260197066
    Abstract: The present disclosure is related to an electronic device and method for reducing a number of coefficients for channel emulation. A method for reducing a number of coefficients for channel emulation comprises: determining multiple beams based on at least first set of channel coefficients for channel emulation; selecting at least one beam from the multiple beams; and determining second set of channel coefficients for channel emulation based on at least the selected at least one beam, the number of channel coefficients in the second set of channel coefficients being less than the number of channel coefficients in the first set of channel coefficients.
    Type: Application
    Filed: November 28, 2022
    Publication date: July 9, 2026
    Inventors: Hao ZHANG, Huaisong ZHU, Ming LEI, Fredrik HUSS, Guangyu YUAN, Chao LI
  • Publication number: 20260167240
    Abstract: The present invention relates to the field of camping equipment, and in particular to a camping vehicle. The camping vehicle comprises a vehicle body, wherein one side of the vehicle body is provided with cross beams, two ends of the cross beams are provided with vertical beams, a backrest is rotatably mounted on the cross beams, a sliding rod is vertically slidably mounted on the backrest, hinged rods are rotatably mounted on the vertical beams, and the hinged rods are rotatably connected to the sliding rod. The camping vehicle provided by the invention has the advantages of an adjustable backrest and comfortable riding.
    Type: Application
    Filed: August 7, 2025
    Publication date: June 18, 2026
    Inventor: MING LEI
  • Patent number: 12656350
    Abstract: The present disclosure provides methods and kits for diagnosing and assessing SAGE1-positive disorders, and compositions and methods for treating SAGE1-positive disorders. The present disclosure further provides SAGE1 complexes and methods and composition for inhibiting SAGE1 complexes and treating SAGE1-positive disorders.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: June 16, 2026
    Assignees: SHANGHAI NINTH PEOPLE'S HOSPITAL, SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE, SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Ming Lei, Wei Deng, Yanjie Zhang, Yang Song, Chao Zheng
  • Patent number: 12640569
    Abstract: The present invention discloses a division method and system for distributed renewable-energy electricity generation clusters, where the method includes: obtaining electric power consumption-absorption data of the electricity-generation clusters; extracting and analyzing the absorbed electricity quantities of the corresponding target single electricity generators or the consumed electricity quantities of the corresponding target energy consumption nodes; constructing and determining consumption-absorption matching groups for a plurality of electricity generator sets and energy consumption districts according to distances from the target single electricity generators to the target energy consumption nodes, and executing division for the electricity-generation clusters. According to the present invention, energy waste can be avoided, and then management efficiency is increased.
    Type: Grant
    Filed: January 2, 2025
    Date of Patent: May 26, 2026
    Inventors: Yu Zhang, Libo Zhang, Nan Mou, Julong Chen, Bin Wang, Jia Yin, Qingsheng Li, Ying Liu, Jierui Yang, Zhaofeng Zhang, Xueyong Tang, Ming Lei, Chao Lin, Yong Yuan, Yanle Liu, Changwen Li
  • Patent number: 12625197
    Abstract: Disclosed in the present disclosure is an underground cable path tester, in which a first signal processing device is connected to a data port of a primary unit central control module, and a second signal processing device is connected to an output port of the first signal processing device; regarding the first signal processing device, data ports of a signal receiving module, a signal amplifying module, a phase-locked loop module, and a secondary unit central control module are sequentially connected; and regarding the second signal processing device, a probe, a filter module, an amplifier module, and an alarm module are sequentially connected.
    Type: Grant
    Filed: July 19, 2024
    Date of Patent: May 12, 2026
    Assignee: Yongzhou Noyafa Electronic Co., Ltd.
    Inventors: Ming Lei, Jianping Zhang
  • Publication number: 20260121685
    Abstract: The present disclosure relates to the technical field of cable locating and pairing. Disclosed are a circuit for implementing cable locating and pairing applied to a cable maintenance equipment and a cable maintenance equipment. The circuit for implementing cable locating and pairing includes a cable locating signal processing circuit and a cable pairing signal transmission circuit. The cable locating signal processing circuit includes a cable locating signal buffer circuit and a cable locating signal transmission circuit. A first terminal of the cable pairing signal transmission circuit is electrically connected to a cable pairing control terminal of the first main control circuit and is configured to be grounded. It is evident that the circuit for implementing cable locating and pairing in the present disclosure is simple in structure and can effectively reduce power consumption of cable locating and pairing.
    Type: Application
    Filed: April 3, 2025
    Publication date: April 30, 2026
    Inventors: Ming Lei, Jianping Zhang
  • Publication number: 20260121404
    Abstract: The present invention discloses a method and a system for controlling an overvoltage in a photovoltaic court based on a floating neutral voltage, including: acquiring, by a controller, a voltage U of the photovoltaic court and a voltage U0 of a transformer neutral point; comparing acquired voltage data with a set threshold; generating control instructions of offsetting and compensation according to a comparison result; and receiving the instructions by a neutral voltage regulator, and controlling a voltage. The present invention introduces a floating neutral line between a photovoltaic power supply and a grid-connected transformer neutral point, and arranges a neutral voltage regulator on the floating neutral line. By adjusting its direction and size, the neutral voltage regulator can adapt to the voltage problem of the court in different states. Meanwhile, by adjusting the voltage on the grid-connected transformer neutral point side, the voltage of the grid-connected transformer neutral point is zero.
    Type: Application
    Filed: January 3, 2025
    Publication date: April 30, 2026
    Inventors: Yu ZHANG, Yan ZHANG, Julong CHEN, Xueyong TANG, Zhaofeng ZHANG, Jierui YANG, Jie WANG, Bin WANG, Leichen YANG, Xin YANG, Yongqing ZHU, Nan MOU, Chuan QIN, Ming LEI, Chao LIN, Qian CHEN
  • Patent number: 12614085
    Abstract: Systems and methods are provided for performing customizable machine prediction using an extensible software tool. A specification including features of a trained machine learning model can be received and an interface for the trained machine learning model can be generated. The trained machine learning model can be loaded using the interface, the loaded machine learning model including a binary file configured to receive data as input and generate prediction data as output. Predictions can be generated using observed data that is stored according to a multidimensional data model, wherein a portion of the observed data is input to the loaded machine learning model to generate first data predictions, and a portion of the observed data is used by a generic forecast model to generate second data predictions. The first and second data predictions can be displayed in a user interface configured to display intersections of the multidimensional data model.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: April 28, 2026
    Assignee: Oracle International Corporation
    Inventors: Ming Lei, Catalin Popescu, Wendy Lewenberg Etkind
  • Patent number: 12601778
    Abstract: Various approaches can be used to interrogate a surface such as a surface of a layered semiconductor structure on a semiconductor wafer. Certain approaches employ Second Harmonic Generation while other utilize four wave-mixing or multi-wave mixing. Corona discharge may be applied to the sample to provide additional information. Some approaches involve determining current flow from a sample illuminated with radiation.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: April 14, 2026
    Assignees: SK HYNIX INC., FEMTOMETRIX, INC.
    Inventors: Seongmin Ma, Sangmin Kim, Jonghoi Cho, Ming Lei
  • Publication number: 20260098327
    Abstract: The present invention discloses coated ultrahigh-strength steel with low spot welding crack sensitivity, comprising a steel substrate and a zinc-containing coating on the surface of the steel substrate. The steel substrate contains Fe and inevitable impurity elements. The steel substrate further contains the following chemical elements in percentage by mass: 0.10-0.30% of C, 0.30-0.90% of Si, 1.00-2.20% of Mn, 0.001-0.003% of B, and 0.30-1.00% of Al. Correspondingly, the present invention further discloses a manufacturing method for the coated ultrahigh-strength steel. The coated ultrahigh-strength steel in the present invention can be effectively prepared by using the manufacturing method, the final yield strength is 600-850 MPa, the tensile strength is 980-1150 MPa, the uniform elongation is not less than 13%, and the elongation at break is not less than 15%.
    Type: Application
    Filed: September 25, 2023
    Publication date: April 9, 2026
    Applicant: BAOSHAN IRON & STEEL CO., LTD.
    Inventors: Hua PAN, Ming LEI, Xinyan JIN, Tao GONG, Haomin JIANG
  • Patent number: 12594321
    Abstract: The invention provides compositions and methods for treating diseases associated with expression of CD20 or CD22. The invention also relates to chimeric antigen receptor (CAR) specific to CD20 or CD22, vectors encoding the same, and recombinant T or natural killer (NK) cells comprising the CD20 CAR or CD22 CAR. The invention also includes methods of administering a genetically modified T cell or NK cell expressing a CAR that comprises a CD20 or CD22 binding domain.
    Type: Grant
    Filed: December 5, 2023
    Date of Patent: April 7, 2026
    Assignees: Novartis AG, The Trustees of the University of Pennsylvania
    Inventors: Barbara Brannetti, Jennifer Brogdon, Boris Engels, Brian Walter Granda, Ming Lei, Jimin Zhang
  • Patent number: 12596672
    Abstract: A method for replacing at least one hardware assembly of a data processing apparatus includes managing, by a system management software, the data processing apparatus with a service processor and a plurality of hardware assemblies, obtaining, by the system management software, first system configuration data, first system vital product data (SVPD), and first server identity data of the data processing apparatus from the service processor or through the service processor, obtaining, by the system management software, second SVD and second server identity data of the data processing apparatus from the service processor or through the service processor, comparing, by the system management software, the first server identity data with the second server identity data, and configuring, by the system management software, the data processing apparatus based on the first system configuration data and the first SVPD according to a comparison result.
    Type: Grant
    Filed: October 11, 2023
    Date of Patent: April 7, 2026
    Assignee: LENOVO (BEIJING) LIMITED
    Inventors: Ming Lei, Fred Allison Bower, III, Caihong Zhang, Jihao Zhang
  • Publication number: 20260092975
    Abstract: In a device operable for determining a state of charge (SOC) of a battery, an acquisition circuit is configured to acquire state parameters of the battery. A processing circuit is configured to: determine a first SOC of the battery by using an AI model based on the state parameters; determine a second SOC of the battery by using a stored lookup table, where the lookup table stores at least a portion of the state parameters and an SOC of the battery in association with each other; and determine a third SOC of the battery by calculating a weighted average of the first SOC of the battery and the second SOC of the battery based on weights of the first SOC of the battery and the second SOC of the battery, where the third SOC represents the SOC of the battery.
    Type: Application
    Filed: September 15, 2025
    Publication date: April 2, 2026
    Inventors: Ming LEI, Jing CHE
  • Patent number: 12591022
    Abstract: A multifunctional line finder for miniature circuit breaker includes an emitter and a receiver, in which the emitter includes an emitting module for emitting line-finding signal and an LNG line-order detection module, the emitting module includes a main control unit, a strong electricity line-finding emitting unit, and a network line-finding emitting unit, the receiver includes a receiving module, an operational amplifier module, a signal processing module, and an audio drive module, a line-finding signal output end of the emitting module is connected to a line-finding signal input end of the receiving module, a signal detecting output end of the LNG line-order detection module is connected to a signal detecting input end of the receiving module, a signal receiving output end of the receiving module is connected to a signal receiving input end of the operational amplifier module.
    Type: Grant
    Filed: June 4, 2024
    Date of Patent: March 31, 2026
    Assignee: Yongzhou Noyafa Electronic Co., Ltd.
    Inventor: Ming Lei
  • Patent number: 12590294
    Abstract: The present invention relates to a process for producing a population of cells which comprises mature atrial cardiomyocytes. The process comprises the step of treating iPS cells according to a treatment regimen which comprises contacting the iPS cells with Gremlin2 and retinoic acid, such that at least a portion of the iPS cells differentiate into mature atrial cardiomyocytes.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: March 31, 2026
    Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Ming Lei, Derek Terrar, Faizzan Ahmad
  • Publication number: 20260078179
    Abstract: The present disclosure provides monoclonal and recombinant anti-CDH17 antibodies (including CDH17 biparatopic and CDH17xCD3 bispecific antibodies and CDH17-binding fragments. Such antibodies and binding fragments are useful for the treatment of cancer, cither alone or in combination with other agents.
    Type: Application
    Filed: July 17, 2025
    Publication date: March 19, 2026
    Inventors: Ming LEI, Han LI, Yi PEI, Haichun HUANG, Di SHEN, Puspa THAPA, Raymond YU
  • Publication number: 20260072100
    Abstract: The present disclosure relates to the technical field of cable testing, disclosing a cable testing device for running lights wire pairing and tracing and a cable tester. By utilizing a main test circuit and a secondary test circuit, the device/tester jointly implements running lights wire pairing and tracing functions for a cable to be test: By implementing, at a first data processing module in the main test circuit, target signal generation and transmission down including a pairing signal and a tracing signal, the first pairing and tracing module cooperates with the first running lights module to respond to the target signal, while the second pairing and tracing module in the secondary test circuit cooperates with the second running lights module to respond to the target signal.
    Type: Application
    Filed: July 25, 2025
    Publication date: March 12, 2026
    Inventors: Ming Lei, Jianping Zhang
  • Publication number: 20260042840
    Abstract: The disclosure provides a method for treating a subject afflicted with a tumor comprising administering to the subject a therapeutically effective amount of an anti-PD-1 antibody or antigen-binding portion thereof or an anti-PD-L1 antibody or antigen-binding portion thereof, wherein the subject is identified as having a low stromal gene signature score. In some aspects, the low stromal gene signature score is determined by measuring the expression of a panel of stromal genes in a tumor sample obtained from the subject, wherein the stromal gene panel comprises at least four genes selected from CDH1, CDH2, MMP1, MMP2, ITGA1, ITGA2, ITGA3, ITGA5, ITGA7, ITGA11, TGFB1, and TGFB1; at least four genes selected from TGFB1, TGFBR2, ACTA2, COL4A1, TAGLN, SH3PXD2A, TWIST1, ZEB1, and ZEB2; or MMP2 and MMP9.
    Type: Application
    Filed: April 7, 2023
    Publication date: February 12, 2026
    Applicants: Bristol-Myers Squibb Company, Celgene Corporation
    Inventors: Ming LEI, Xuya WANG, Elaine JOSEPH, Ke XU, Danielle Marie GREENAWALT, Peter M. SZABO, Alice M. WALSH, Michael CARLETON, Qu ZHANG, Jin YAO