Patents by Inventor Mitsuo Numata

Mitsuo Numata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-(Morpholinoalkoxyiminomethyl)cephem compounds
    Patent number: 4011214
    Abstract: Novel cephalosporin compounds of the formula ##STR1## wherein R.sup.1 is an acyl group and R.sup.2 is an alkylene group which may be substituted with a lower alkoxyl group, or pharmaceutically acceptable salt thereof, have strong inhibitory actions on broad spectra of gram-positive and gram-negative bacteria and, particularly against Esherichia coli and Klebsiella pneumoniae. Thus, the compounds are useful as therapeutic agent for various bacterial infections of animals including human beings.
    Type: Grant
    Filed: December 20, 1974
    Date of Patent: March 8, 1977
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Shinji Terao, Mitsuru Shiraishi, Toshio Miyawaki, Isao Minamida, Masayoshi Yamaoka, Mitsuo Numata
  • Process for producing lactol-type cephalosporins
    Patent number: 3984401
    Abstract: A 3-hydroxymethylcephalosporin which is not protected at the carboxyl group can be directly oxidized with a hexavalent chromium compound to give in good yield a lactol type cephalosporin represented by the general formula: ##SPC1##Wherein R.sup.1 is hydrogen or an alkoxy group and R.sup.2 is an acylamino, or imido group. The resulting compounds are very useful and important as intermediates for preparing, e.g. 3-alkoxyiminomethyl cephalosporins.
    Type: Grant
    Filed: December 7, 1973
    Date of Patent: October 5, 1976
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Shinji Terao, Mitsuru Shiraishi, Toshio Miyawaki, Isao Minamida, Masayoshi Yamaoka, Yoshio Imashiro, Mitsuo Numata