Abstract: A mist generator device (400) for delivering a mist to a user, the mist generator device (400) for use with a driver device (202). The mist generator device (400) comprises a housing (204) comprising a liquid chamber (218) for containing a liquid to be atomised, a sonication assembly (425) coupled to the housing (204) the sonication assembly (425) comprising an ultrasonic transducer (215), a first assembly portion (426) and a second assembly portion (428) coupled to the first assembly portion (426). At least one of the first assembly portion (426) and the second assembly portion (428) comprises a resiliently deformable section that forms a seal between the first assembly portion (426) and the second assembly portion (428) which minimises or prevents a fluid from leaking between the first assembly portion (426) and the second assembly portion (428).

Abstract: A mist generator device (400) for delivering a mist to a user, the mist generator device (400) for use with a driver device (202). The mist generator device (400) comprises a housing (204) comprising a liquid chamber (218), the liquid chamber containing a liquid to be atomised, the liquid comprising a therapeutic. A sonication assembly (425) is coupled to the housing (204) the sonication assembly (425) comprising an ultrasonic transducer (215), a first assembly portion (426) and a second assembly portion (428) coupled to the first assembly portion (426). At least one of the first assembly portion (426) and the second assembly portion (428) comprises a resiliently deformable section that forms a seal between the first assembly portion (426) and the second assembly portion (428) which minimises or prevents a fluid from leaking between the first assembly portion (426) and the second assembly portion (428).

Abstract: Improved flow indwelling urinary catheters are disclosed in which inflow openings at a distal end of a catheter are distally biased and in proximity to a distal end of a catheter balloon resulting in greater urine outflow volume and velocity, greater urine emptying volume from the bladder and patent urine outflow as the catheter is withdrawn from the bladder.

Abstract: A dialog tree generation system is provided, including a processor, and a memory storing instructions that, when executed by the processor, cause the system to receive documents, parse the documents into raw blocks, extract visual design elements from the raw blocks, generate a content structure from the extracted visual design elements, generate at least a dialog decision tree based on the extracted content structure, the dialog decision tree comprising a plurality of nodes organized into a hierarchy, and output the dialog decision tree.

Abstract: A peptide that binds to the Si spike protein of Middle East Respiratory syndrome coronavirus or MERS-CoV and a method for inhibiting infection of a subject exposed to or having MERS-CoV by administering the peptide.

Abstract: A catalyst gauze for an ammonia oxidation process is described, containing a first layer of knitted first wire material, whereby said first wire material is made from a platinum-rhodium alloy, characterized in that said first layer contains an activator in the form of a second wire material which is knitted among the first wire material and which is made from un-alloyed platinum.

Abstract: System for the purpose of realizing wellness and wellbeing that enables users to define personal wellness and wellbeing objectives that establish the scope of contextualizing user specific condition. The system collects and co-analyzes ambient pollution and physiological biomarkers data that include ambient airborne pollution, electric field radiation pollution, magnetic field radiation pollution, RF signal radiation pollution, temperature changes, relative humidity, and users' physiological biomarkers. The system operates in three modes: interactive, passive, and physical mode, and it uses range extender remote ambient pollution monitors to cover any desired indoor-space. The system is built on a universal holder that expands and retracts both vertical and horizontal dimensions to fit as a protective case and sleeve for various sizes of smartphone and handheld devices.

Abstract: Aspects of the present application provide methods and devices for using a combined QAM and APSK modulation scheme in a hybrid modulation form in order to benefit from advantages of each respective modulation scheme. The proposed hybrid modulation scheme is less sensitive to phase noise and has lower PAPR than QAM and has very similar performance as QAM with respect to AWGN.

Abstract: The present invention relates to composition, formulations and devices for preventing vasovagal syncope attack, and in particular to the use of combinations of capsaicin, caffeine, and/or ?-agonists to prevent syncope.

Abstract: Aspects of the present application provide methods and devices for using a combined QAM and APSK modulation scheme in a hybrid modulation form in order to benefit from advantages of each respective modulation scheme. The proposed hybrid modulation scheme is less sensitive to phase noise and has lower PAPR than QAM and has very similar performance as QAM with respect to AWGN.

Abstract: Improved flow indwelling urinary catheters are disclosed in which inflow openings at a distal end of a catheter are distally biased and in proximity to a distal end of a catheter balloon resulting in greater urine outflow volume and velocity, greater urine emptying volume from the bladder and patent urine outflow as the catheter is withdrawn from the bladder.

Abstract: A tissue harvesting device (1), comprising a rotary cutting tool (10) adapted to cut soft tissue and a collection container (20) including a central bore (21) extending in a longitudinal direction and with a distal opening (22), wherein the cutting tool is arranged in the central bore of the collection container and adapted to pass through the distal opening and draw harvested soft tissue fragments into the collection container, and a housing (30) accommodating the cutting tool and the collection container, wherein the collection container is axially movable with respect to the housing.

Abstract: A peptide that binds to the Si spike protein of Middle East Respiratory syndrome coronavirus or MERS-CoV and a method for inhibiting infection of a subject exposed to or having MERS-CoV by administering the peptide.

Abstract: A transdermal delivery device (10, 10?) includes at least one of a backing layer (14) and a removable release liner (16). An active layer (12, 12?) is supported by the backing layer and/or release liner. The active layer includes a polymer matrix, a therapeutically/cosmetically effective amount of an active agent dispersed in the polymer matrix, and a pressure sensitive adhesive, incorporated in the polymer matrix and/or adhered thereto. The polymer matrix includes a thermoplastic polyurethane polymer and optionally, a poly(meth)acrylate polymer. The thermoplastic polyurethane polymer includes the reaction product of: a first polyether polyol A having a molecular weight of at least 3000 daltons and/or a second polyether polyol B having a molecular weight of no more than 2500 daltons; a third polyol C having a molecular weight of up to 800 daltons and/or a chain extender; a polyisocyanate; and optionally a catalyst.

Abstract: Provided herein are methods of treating acute myeloid leukemia (AML) and multiple myeloma (MM) by administering an effective amount of a cell population comprising natural killer cells, wherein the cell population comprising natural killer cells is produced by a three-stage method comprising culturing a population of hematopoietic stem or progenitor cells in media comprising stem cell mobilizing factors, e.g., three-stage methods of producing NK cells in media comprising stem cell mobilizing factors starting with hematopoietic stem or progenitor cells from cells of the placenta, for example, from placental perfusate (e.g., human placental perfusate) or other tissues, for example, umbilical cord blood or peripheral blood. Further provided herein are methods of using the NK cells produced by the three-stage methods provided herein to suppress the proliferation of acute myeloid leukemia cells.

Abstract: A tissue harvesting device (1), comprising a rotary cutting tool (10) adapted to cut soft tissue and a collection container (20) including a central bore (21) extending in a longitudinal direction and with a distal opening (22), wherein the cutting tool is arranged in the central bore of the collection container and adapted to pass through the distal opening and draw harvested soft tissue fragments into the collection container, and a housing (30) accommodating the cutting tool and the collection container, wherein the collection container is axially movable with respect to the housing.

Abstract: Methods of treating, preventing and/or managing multiple myeloma are disclosed. Specific methods encompass the administration of an immunomodulatory compound, e.g., lenalidomide or pomalidomide with an anti-CS1 antibody, e.g., elotuzumab in patients who have received autologous stem cell transplantation.

Abstract: A terminal holder is provided for connecting a cable to a connector or another cable. The terminal holder includes a base plate configured to be held proximate an end of the cable. The base plate includes an edge. Terminal sleeves extend from the edge of the base plate for holding cable terminals of the cable and connector terminals of the connector or of the other cable. The terminal sleeves have internal passages extending from a cable end to a connector end. The internal passage is configured to receive a corresponding cable terminal therein through the cable end. The internal passage is configured to receive a corresponding connector terminal therein through the connector end such that the corresponding cable terminal and the corresponding connector terminal are engaged in electrical contact with each other within the internal passage.

Abstract: A terminal holder is provided for connecting a cable to a connector or another cable. The terminal holder includes a base plate configured to be held proximate an end of the cable. The base plate includes an edge. Terminal sleeves extend from the edge of the base plate for holding cable terminals of the cable and connector terminals of the connector or of the other cable. The terminal sleeves have internal passages extending from a cable end to a connector end. The internal passage is configured to receive a corresponding cable terminal therein through the cable end. The internal passage is configured to receive a corresponding connector terminal therein through the connector end such that the corresponding cable terminal and the corresponding connector terminal are engaged in electrical contact with each other within the internal passage.

Abstract: Methods of treating, preventing and/or managing multiple myeloma are disclosed. Specific methods encompass the administration of an immunomodulatory compound, e.g., lenalidomide or pomalidomide with an anti-CS1 antibody, e.g., elotuzumab in patients who have received autologous stem cell transplantation.