Abstract: The present invention relates to certain amide derivatives that have the ability to inhibit 11-?-hydroxysteroid dehydrogenase type 1 (11?-HSD-1) and which are therefore useful in the treatment of certain disorders that can be prevented or treated by inhibition of this enzyme. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders. It is expected that the compounds of the invention will find application in the treatment of conditions such as non-insulin dependent type 2 diabetes mellitus (NIDDM), insulin resistance, obesity, impaired fasting glucose, impaired glucose tolerance, lipid disorders such as dyslipidemia, hypertension and as well as other diseases and conditions.

Abstract: A method and apparatus for detecting and engaging participants in an online course that are not likely to attend the online course, is presented herein. Participants in an online course are responsible for attending the course by downloading instructional material and completing assignments through an online forum. Attending the online course causes interaction data and/or performance data to be generated and stored for each participant. The interaction and performance data for a particular participant may be analyzed to determine whether the particular participant is likely to not attend the online course during a future period. If the particular participant is not likely to attend the online course during the future period, an alert is a counselor to intervene and engage the participant. A counselor may follow up with the particular participant to make sure the participant is on track to attend and complete the online course.

Abstract: A hand-held communication device capable of being configured as a pointing device employs a camera assembly for sensing movement of the device with respect to a surface, or movement of a user's finger over the camera assembly, allowing the hand-held communication device to be utilized as a pointing device, such as an optical mouse or a trackball, for controlling functions of a computer system in communication with the hand-held communication device or of the hand-held communication device.

Abstract: The present invention relates to antithrombotic compounds 2-alkyl aryl sulphonyl-1,2,3,4-tetrahydro-9H-pyrido(3,4-b) indole-3-carboxylic acid esters/amides, pharmaceutically acceptable salts and compositions thereof to be used in the treatment of intravascular thrombosis such as myocardial ischemia and stroke. The compound has the following general structure wherein R represents methyl ester or amide and R1 represents alkyl, aryl and heteroaryl moiety.

Abstract: Isolator assemblies and isolators between separate parts or components, and, particularly, multi stage isolators, especially, isolators useful in automotive applications are described. The isolators have a tubular cross section, made of the same material as the isolator body, which can flex when in a deflection stage, or can compress in a compression stage, thus allowing for reduced wear and/or longer life for both the isolator and the parts and components separated thereby.

Abstract: Isolator assemblies and isolators between separate parts or components, and, particularly, multi stage isolators, especially, isolators useful in automotive applications are described. The isolators have non perpendicular ribs, made of the same material as the isolator body, which can flex when in a deflection phase or stage, or can compress in a compression phase or stage, thus allowing for reduced wear and/or longer life for both the isolator and the parts and components separated thereby.

Abstract: Isolator assemblies and isolators between separate parts or components, and, particularly, multi stage isolators, especially, isolators useful in automotive applications are described. The isolators have a conical cross section, made of the same material as the isolator body, which can flex when in a deflection stage, or can compress in a compression stage, thus allowing for reduced vibration transmission and/or wear or longer life for both the isolator and the parts and components separated thereby.

Abstract: A system includes determination of a service to perform with respect to data stored in the device, determination of a plurality of sub-services corresponding to the service, determination of an execution sequence for the plurality of sub-services, communication of the execution sequence to each of a plurality of local external devices, each of the plurality of local external devices to perform at least one of the plurality of sub-services in accordance with the execution sequence, and transmission of the data to at least a first of the plurality of local external devices.

Abstract: A system for a mobile telephone includes query of a first local external device for first contact information, and reception of the first contact information from the first local external device. According to some aspects, a system for a mobile telephone includes reception of a query from a first local external device for first contact information stored in the mobile telephone, and transmission of the first contact information to the first local external device.

Abstract: In some embodiments, systems and methods for remote cross-platform instructions are provided. According to some embodiments, instructions defined at a first device may be translated and executed by a second device.

Abstract: A vehicle includes a communication unit for communicating with a wireless device including a selection portion and a command portion. The selection portion provides an interface for a user to select functions of the vehicle for control by the wireless device. The command portion of the communication unit receives user input from the selection portion. The command portion includes a controller that accepts the user input from the selection portion and generates the wireless communications to the wireless device. The wireless communications enable the wireless device to communicate with the command portion, which then controls the desired vehicle function.

Abstract: The present invention relates to antithrombotic compounds 2-alkyl aryl sulphonyl-1,2,3,4,-tetrahydro-9H-pyrido(3,4-b)indole-3-carboxylic acid esters/amides, pharmaceutically acceptable salts and compositions thereof to be used in the treatment of intravascular thrombosis such as myocardial ischemia and stroke. The compound has the following general structure wherein R represents methyl ester or amide and R1 represents alkyl, aryl and heteroaryl moiety.

Abstract: A hand-held communication device capable of being configured as a pointing device employs a camera assembly for sensing movement of the device with respect to a surface, or movement of a user's finger over the camera assembly, allowing the hand-held communication device to be utilized as a pointing device, such as an optical mouse or a trackball, for controlling functions of a computer system in communication with the hand-held communication device or of the hand-held communication device.

Abstract: An improved laryngoscope blade, where the lingual side of the blade, being the side that is presented against a patient's tongue during examination, defines a concave area which defines a cavity which allows the patient's tongue to be cradled during the examination, and where the curved descending sides of the blade proiaote and urge the tongue into the cavity area, and prevent the tongue from flattening out sufficiently so as to curve over onto the top side of the blade, where the view of the patient's airway would be obstructed.