Abstract: Provided herein are methods of producing extracellular matrix (ECM) that are superior to previously-described methods. Extracellular matrix (ECM) comprises protein that forms many structures in the body including tendons, ligaments, and sheets that support skin and internal organs. There remains a need in the art for ECM compositions that have improved cell attachment characteristics and methods of making such ECM compositions.

Abstract: Methods of treatment, diagnosis, and determining prognosis of subjects with cancer, generally comprising determining levels of glycine metabolism or a mitochondrial 1-carbon (1-C) pathway enzyme, e.g., SHMT2, MTHFD1L, or MTHFD2, and optionally administering an antifolate or an agent that inhibits a mitochondrial 1-carbon (1-C) pathway enzyme, e.g., SHMT2 or MTHFD2.

Abstract: A localized repair method in a network using a control plane includes, responsive to a failure on a local repair segment defined on a connection traversing the network, generating a release message in the control plane; attempting a local repair on the local repair segment; if the local repair is unsuccessful, transmitting the release message to redial the connection; and, if the local repair is successful, signaling a new sub-path based on the local repair. A controller and a network are also disclosed.

Abstract: A method, in an intermediate node in a control plane network, includes receiving a setup message from an originating node, wherein the setup message is sent towards a terminating node on a computed path in the control plane network, and the setup message indicates associated Layer 0 attributes; validating the associated attributes/constraints based on locally available resources; and performing one of: forwarding the setup message on the path towards the terminating node when validation is successful; forwarding the setup message on the path towards the terminating node with updated information indicating a rejection cause and additional information when the validation is unsuccessful, but a modification of the Layer 0 attributes/constraints is possible; and forwarding a release message on the path back to the originating node with updated information indicating a rejection cause and additional information when the validation is unsuccessful and no modifications of the Layer 0 attributes/constraints are possi

Abstract: Techniques for cloning, writing to, and reading from file system metadata. Cloning involves identifying a first set of pointers included in a first root node in a file system metadata tree structure that stores file system metadata in leaf nodes of the tree structure, creating a first copy of the first root node that includes the first set of pointers, creating a second copy of the first root node that includes the first set of pointers, associating the first copy with a first view, and associating the second copy with a second view. Reading generally involves traversing the tree structure towards a target leaf node that contains data to be read. Writing generally involves traversing the tree structure in the same manner, but also creating copies of any nodes to be modified if those nodes are deemed to have a different treeID than a particular root node.

Abstract: Methods and nodes are disclosed for OAM configuring one or more tandem connection monitoring layers through GMPLS signaling during GMPLS sub-network connection (SNC) establishment. Additionally, methods and nodes are disclosed for OAM configuring one or more tandem connection monitoring layers through GMPLS signaling after GMPLS sub-network connection establishment, that is, for existing connections.

Abstract: Systems and methods for accessing network configuration data identifying one or more working path(s) configured to transport data between source and destination nodes, wherein multiple working paths are prioritized, and including at least one first diversity weight of a first value indicative of at least one communication link in the working path(s), and at least one second diversity weight of a second value indicative of at least one communication link outside of the working path(s); calculating a disjoint protection path with the network configuration data, the first diversity weight, and the second diversity weight; the disjoint protection path including at least the source node and the destination node and at least one communication link that is mutually exclusive from the at least one communication link of the first set; and outputting at least one setup signal to configure the disjoint protection path within the mesh network.

Abstract: A method, a network element, and a network operating an Ethernet service include transmitting information related to an operational speed of a first connection to the second switch, wherein the first switch is connected to a first Customer Premises Equipment (CPE) device through the first connection and the second switch is connected to a second CPE device through a second connection; receiving information related to an operational speed of the second connection; and triggering a modification to the Ethernet service, responsive to a mismatch between the operational speed of the first connection and the operational speed of the second connection.

Abstract: New polymer compositions based on poly(2,6-dimethyl-1,4-phenylene oxide) and other high-softening-temperature polymers are disclosed. These materials have a microphase domain structure that has an ionically-conductive phase and a phase with good mechanical strength and a high softening temperature. In one arrangement, the structural block has a softening temperature of about 210° C. These materials can be made with either homopolymers or with block copolymers.

Abstract: Disclosed is an approach for implementing disaster recovery for virtual machines. Consistency groups are implemented for virtual machines, where the consistency group link together two or more VMs. The consistency group includes any set of VMs which need to be managed on a consistent basis in the event of a disaster recovery scenario.

Abstract: In various example embodiments, a system and method for using machine learning to define user controls for image adjustment is provided. In example embodiments, a new image to be adjusted is received. A weight is applied to reference images of a reference dataset based on a comparison of content of the new image to the reference image of the reference dataset. A plurality of basis styles is generated by applying weighted averages of adjustment parameters corresponding to the weighted reference images to the new image. Each of the plurality of basis styles comprises a version of the new image with an adjustment of at least one image control based on the weighted averages of the adjustment parameters of the reference dataset. The plurality of basis styles is provided to a user interface of a display device.

Abstract: Embodiments of the present invention provide systems, devices and methods for improving the efficient deployment and configuration of networking equipment within a network build-out. In certain embodiments of the invention, an iterative analysis of inter-node equipment placement and connectivity, and inter- and intra-node traffic flow is performed to identify a preferred deployment solution. This analysis of deployment optimization takes into account both configurations from a network node perspective as well as from a network system perspective. Deployment solutions are iteratively progressed and analyzed to determine a preferred solution based on both the cost of deployment and satisfaction of the network demands. In various embodiments of the invention, a baseline marker is generated from which the accuracy of the solution may be approximated that suggests to an engineer whether the deployment is approaching an optimal solution.

Abstract: Techniques are disclosed for allocating shared resources to nodes in a distributed computing network system. Nodes request a lock for each instance of a computing resource (e.g., a virtual IP address associated with a service provided by the distributed computing network system) from a distributed lock manager. The distributed lock manager maintains a queue of requests for each instance of the shared resource. Upon receiving a lock from the distributed lock manager, the receiving node performs a fairness allocation protocol to determine whether to accept the lock. If so determined, the shared computing resources associated with the lock is configured.

Abstract: Systems, methods, and computer program products for managing a consensus group in a distributed computing cluster, by determining that an instance of an authority module executing on a first node, of a consensus group of nodes in the distributed computing cluster, has failed; and adding, by an instance of the authority module on a second node of the consensus group, a new node to the consensus group to replace the first node. The new node is a node in the computing cluster that was not a member of the consensus group at the time the instance of the authority module executing on the first node is determined to have failed.

Abstract: A composite fuel tank, formed by winding filaments or strips around a plastic liner and binding the material with a curable binder. Embedded within the wrapped material at predetermined depths from the surface which provides a color indication of the level of damage due to tears, gashes, cuts and the like. The color indicator is part of a visual inspection method to determine tank damage and the extent of repair necessary.

Abstract: Embodiments of the invention are directed to systems, methods and computer program products for use in financial systems, where message are automatically generated based on message templates. An exemplary apparatus is configured to access a click to launch tool that is configured to automatically generate messages based at least partially on one or more message templates. After selecting a message type presented within the click to launch tool, the system may receive information via a message template associated with the selected message type and related to a financial agreement. A message comprising the received information is automatically generated and sent the message to one or more entities associated with the financial agreement.

Abstract: A method, a system, and a network for coordination between a data control plane and photonic control in a network include operating the data control plane with photonic control messaging included therein, wherein the data control plane is configured to at least establish end-to-end paths between a plurality of network elements at Layer 1; transmitting a photonic control message in or by the data control plane responsive to a requirement for photonic layer information; processing, via the data control plane, the photonic layer information received from photonic control responsive to the photonic control message, wherein the photonic control is configured to adjust photonic hardware responsive to a change at a photonic layer; and performing an action by the data control plane considering the photonic layer information.

Abstract: A processor-implemented method for a secure processing environment for protecting sensitive information is provided. The processor-implemented method may include receiving encrypted data and routing the encrypted data to the secure processing environment. Then the encrypted data may be decrypted and fields containing sensitive information may be found. The method may also include obfuscating the sensitive information and returning, by the secure processing environment, the decrypted data and obfuscated data.

Abstract: Intelligent markers and a card distribution error reduction system are disclosed. In one embodiment, the invention includes intelligent markers which are effectively “player acknowledgement” indicators. The markers preferably include a mechanism for signaling the receiving bettor to acknowledge receipt of the marker, which acknowledgement may turn off the indicating mechanism. The method of indication could be visual, audible or otherwise which would signal a bettor to interact with the marker. The intelligent markers communicate with table sensors and a shoe to monitor the status of games, and to signal alerts when a mistake occurs.

Abstract: A method, system and computer program product are disclosed for generating clock signals for a cycle accurate FPGA based hardware accelerator used to simulate operations of a device-under-test (DUT). In one embodiment, the DUT includes multiple device clocks generating multiple device clock signals at multiple frequencies and at a defined frequency ratio; and the FPG hardware accelerator includes multiple accelerator clocks generating multiple accelerator clock signals to operate the FPGA hardware accelerator to simulate the operations of the DUT. In one embodiment, operations of the DUT are mapped to the FPGA hardware accelerator, and the accelerator clock signals are generated at multiple frequencies and at the defined frequency ratio of the frequencies of the multiple device clocks, to maintain cycle accuracy between the DUT and the FPGA hardware accelerator. In an embodiment, the FPGA hardware accelerator may be used to control the frequencies of the multiple device clocks.