Patents by Inventor Mona Patel

Mona Patel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7928246
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: April 19, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Hiayan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang, Mary Pat Beavers, Maud Urbanski, Min (Amy) Xiang, Roxanne Zeck
  • Patent number: 7825111
    Abstract: The invention is directed to nonpeptide substituted spiroheterobenzazepine of Formula I, which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.
    Type: Grant
    Filed: September 19, 2007
    Date of Patent: November 2, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Min A. Xiang, Mona Patel, Philip Rybczynski, Joseph Gunnet, Keith T. Demarest, Richard Look, Bruce Maryanoff, Michael J. Costanzo, Stephen C. Yabut
  • Patent number: 7825110
    Abstract: The invention is directed to nonpeptide substituted spiroheterobenzazepine of Formula I, which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal insufficiency, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.
    Type: Grant
    Filed: September 19, 2007
    Date of Patent: November 2, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Min A. Xiang, Mona Patel, Philip Rybczynski, Joseph Gunnet, Keith T. Demarest, Richard Look, Bruce Maryanoff, Michael J. Costanzo, Stephen C. Yabut
  • Patent number: 7820630
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: October 26, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Patent number: 7816331
    Abstract: Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: October 19, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mona Patel, Philip J. Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Patent number: 7687494
    Abstract: The invention is directed to nonpeptide substituted benzazepines of Formula I, which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension, among others disclosed. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.
    Type: Grant
    Filed: April 13, 2007
    Date of Patent: March 30, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mona Patel, Philip J. Rybczynski, Min Amy Xiang
  • Publication number: 20100062971
    Abstract: Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Application
    Filed: September 22, 2009
    Publication date: March 11, 2010
    Inventors: Mona Patel, Philip J. Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Publication number: 20100009900
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Application
    Filed: September 22, 2009
    Publication date: January 14, 2010
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Publication number: 20090202525
    Abstract: The present invention relates to compounds of Formula (1), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Application
    Filed: April 15, 2009
    Publication date: August 13, 2009
    Inventors: Haiyan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang, Mary Pat Beavers, Maud Urbanski, Min (Amy) Xiang, Roxanne Zeck
  • Patent number: 7531671
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: May 12, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Hiayan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang
  • Publication number: 20090105164
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Application
    Filed: December 18, 2008
    Publication date: April 23, 2009
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Publication number: 20090099104
    Abstract: Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Application
    Filed: December 18, 2008
    Publication date: April 16, 2009
    Inventors: Mona Patel, Philip J. Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Patent number: 7511022
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Grant
    Filed: June 15, 2006
    Date of Patent: March 31, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Patent number: 7511021
    Abstract: Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: March 31, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Mona Patel, Philip J. Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Publication number: 20080076754
    Abstract: The invention is directed to nonpeptide substituted spiroheterobenzazepine of Formula I, which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.
    Type: Application
    Filed: September 19, 2007
    Publication date: March 27, 2008
    Inventors: Min Xiang, Mona Patel, Philip Rybczynski, Joseph Gunnet, Keith Demarest, Richard Look, Bruce Maryanoff, Michael Costanzo, Stephen Yabut
  • Publication number: 20080076753
    Abstract: The invention is directed to nonpeptide substituted spiroheterobenzazepine of Formula I, which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal insufficiency, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.
    Type: Application
    Filed: September 19, 2007
    Publication date: March 27, 2008
    Inventors: Min Xiang, Mona Patel, Philip Rybczynski, Joseph Gunnet, Keith Demarest, Richard Look, Bruce Maryanoff, Michael Costanzo, Stephen Yabut
  • Publication number: 20070179128
    Abstract: The invention is directed to nonpeptide substituted benzazepines of Formula I, which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension, among others disclosed. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.
    Type: Application
    Filed: April 13, 2007
    Publication date: August 2, 2007
    Inventors: Mona Patel, Philip Rybczynski, Min Xiang
  • Publication number: 20070099936
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Application
    Filed: October 30, 2006
    Publication date: May 3, 2007
    Inventors: Hiayan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang
  • Patent number: 7129220
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: October 31, 2006
    Assignee: Janssen Pharmaceutica N.V
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Publication number: 20060217323
    Abstract: Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Application
    Filed: June 2, 2006
    Publication date: September 28, 2006
    Inventors: Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang