Abstract: Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.

Abstract: Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.

Abstract: The present invention relates to tricyclic 2-pyridone compounds of formula (I): or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.

Abstract: Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.

Abstract: The invention is directed to nonpeptide substituted benzazepines of Formula I, which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension, among others disclosed. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.

Abstract: A system (100) and method (10) for automated collection of data from a transportation vehicle (14) having a wireless transmitter (12) connected to a diagnostic service bus (16). The wireless transmitter (12) is in communication with a server (22) for processing and displaying the collected data.

Abstract: A system (100) and method (10) for automated collection of data from a transportation vehicle (14) having a wireless transmitter (12) connected to a diagnostic service bus (16). The wireless transmitter (12) is in communication with a server (22) for processing and displaying the collected data.

Abstract: A method of inventory control at a service area site for transportation vehicles having an active RF transmitter connected to a service bus, whereby the service area site has a server in communication with the transmitter on the vehicle. The server automatically collects information from the vehicles relative to inventory management without the need for manual intervention. In another embodiment the inventory management method is expanded to include service management at a fleet or rental vehicle site.

Abstract: The present invention relates to tricyclic 2-pyridone compounds of formula (I): 1

Abstract: The present invention relates to tricyclic compounds of formula (I): 1

Abstract: The present invention relates to tricyclic 2-pyridone compounds of formula (I): or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

Abstract: The present invention relates to tricyclic compounds of formula (I): or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

Abstract: The present invention relates to benzoxazinones of formula I: or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, methods of using the same for treating viral infection or as an assay standard or reagent, and intermediates and processes for making the same.

Abstract: The present invention relates to tricyclic 2-pyridone compounds of formula (I): 1

Abstract: The present invention relates to benzoxazinones of formula I: 1

Abstract: The present invention relates to benzoxazinones of formula I: or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, methods of using the same for treating viral infection or as an assay standard or reagent, and intermediates and processes for making the same.

Abstract: This invention relates generally to quinolin-2(1H)-ones and derivatives thereof of Formula (I): or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, pharmaceutical compositions and diagnostic kits comprising the same, methods of using the same for treating viral infection or as assay standards or reagents, and intermediates and processes for making the same.

Abstract: The potent reverse transcriptase inhibitor (−)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-3,4-dihydro-2(1H)-quinazolinone is produced in solvate and crystalline form. These forms are designated Forms 1 and 2, and are characterized by x-ray powder diffraction and differential scanning calorimetry. Pharmaceutical compositions and methods are useful for the treatment of the human immunodeficiency virus (HIV).

Abstract: An intra-luminal device comprises a flow retainer and/or modulator for maintaining an embolic mass within an aneurysm and, optionally, for diverting or modulating fluid flow, and an anchoring element for fixating the retainer within a lumen in a patient's body. The retainer is introduced into the body lumen and positioned with the retainer across the entrance to a body cavity or a body lumen with an embolic mass disposed within to prevent the embolic mass from migrating into the patient's vasculature. The retainer may also be a diverter or modulator used to divert or modulate the luminal fluid flow to the entrance to the body cavity or lumen. The anchoring element, which may be attached to the retainer, is deployed to permanently secure the retainer within the body lumen in the desired position.