Patents by Inventor Monica Garcia Lopez

Monica Garcia Lopez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100197939
    Abstract: The invention provides a new enantioselective process for the preparation of (S)-pregabalin, or a pharmaceutical acceptable addition acid salt comprising: acid hydrolysis of the dioxolan ring of a chiral compound of general formula (I) to obtain compound of general formula (II); oxidation of compound (II) to obtain a compound of general formula (III) and transforming compound (III) into compound of general formula (IV); subjecting compound (IV) to basic hydrolysis to obtain a compound of general formula (V) which is reduced to obtain enantiomerically pure S-pregabalin. The invention also provides new chiral intermediates involved in the process.
    Type: Application
    Filed: July 17, 2008
    Publication date: August 5, 2010
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Rosa M. Ortuno, Sandra Izquierdo, Helmut Heinrich Buschmann, Antoni Torrens Jover, Monica Garcia Lopez
  • Publication number: 20100152252
    Abstract: The present invention relates to heterocyclyl-substituted-ethylamino-phenyl compounds of general formula (I), wherein K-L-M-N, Z and R1, R2, R3, R4 are as described in the claims methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans or animals.
    Type: Application
    Filed: December 21, 2007
    Publication date: June 17, 2010
    Applicant: LABORATORIOS DEL DR. ESTEVE,S.A.
    Inventors: Mónica Garcia-López, Antonio Torrens-Jover, Luz Romero-Alonso, Helmut H. Buschmann
  • Publication number: 20100105684
    Abstract: The present invention relates to heterocyclyl-substituted-tetrahydro-naphthalen-amine compounds of general formula (I) and compositions thereof, methods for their preparation, and the use of said compounds for the treatment or prophylaxis of various disorders of humans or animals.
    Type: Application
    Filed: March 28, 2008
    Publication date: April 29, 2010
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Monica Garcia-Lopez, Antonio Torrens-Jover, Helmut Buschmann
  • Publication number: 20100099703
    Abstract: The present invention relates to phenylamino-substituted piperidine compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans or animals.
    Type: Application
    Filed: October 31, 2007
    Publication date: April 22, 2010
    Inventors: Mónica Garcia-López, Josep Mas-Prio, Antonio Torrens-Jover
  • Publication number: 20100035936
    Abstract: The present invention relates to heterocyclyl-substituted-tetrahydro-naphthalen compounds of general formula (I), methods for their preparation, and compositions comprising these compounds as well as their use for the treatment or prophylaxis of various disorders in humans or animals.
    Type: Application
    Filed: February 6, 2008
    Publication date: February 11, 2010
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Monica Garcia-Lopez, Antonio Torrens-Jover, Helmut Buschmann
  • Publication number: 20090163542
    Abstract: The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline substituted sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.
    Type: Application
    Filed: August 18, 2005
    Publication date: June 25, 2009
    Inventors: Antoni Torrens Jover, Josep Mas Prio, Susana Yenes Minguez, Monica Garcia Lopez, Alberto Dordal Zueras, Luz Romero Alonso, Helmut Henrich Buschmann
  • Publication number: 20090088450
    Abstract: The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline propyl sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.
    Type: Application
    Filed: August 18, 2005
    Publication date: April 2, 2009
    Inventors: Antoni Torrens Jover, Josep Mas Prio, Susana Yenes Minguez, Monica Garcia Lopez, Albert Dordal Zueras, Lus Romero Alonso, Hulmut Henrich Buschmann
  • Patent number: 7211585
    Abstract: The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline substituted sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.
    Type: Grant
    Filed: August 18, 2004
    Date of Patent: May 1, 2007
    Assignee: Laboratorios del Dr. Esteve, S.A.
    Inventors: Antoni Torrens Jover, Josep Mas Prio, Susana Yenes Minguez, Monica Garcia Lopez, Alberto Dordal Zueras, Luz Romero Alonso, Helmut H. Buschmann
  • Patent number: 7211584
    Abstract: The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline propyl sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.
    Type: Grant
    Filed: August 18, 2004
    Date of Patent: May 1, 2007
    Assignee: Laboratorios del Dr. Esteve, S.A.
    Inventors: Antoni Torrens Jover, Josep Mas Prio, Susana Yenes Minguez, Monica Garcia Lopez, Alberto Dordal Zueras, Luz Romero Alonso, Helmut H. Buschmann
  • Publication number: 20060040978
    Abstract: The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline substituted sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.
    Type: Application
    Filed: August 18, 2004
    Publication date: February 23, 2006
    Inventors: Antoni Torrens Jover, Josep Mas Prio, Susana Yenes Minguez, Monica Garcia Lopez, Alberto Dordal Zueras, Luz Romero Alonso, Helmut Buschmann
  • Publication number: 20060040977
    Abstract: The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline propyl sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.
    Type: Application
    Filed: August 18, 2004
    Publication date: February 23, 2006
    Inventors: Antoni Torrens Jover, Josep Mas Prio, Susana Yenes Minguez, Monica Garcia Lopez, Alberto Dordal Zueras, Luz Romero Alonso, Helmut Buschmann