Abstract: Provided is an apparatus for culturing a cell and analyzing a cell reaction. The apparatus may include a plurality of cell culturing rooms, cell injection ports connected to the cell culturing rooms through cell injection channels, respectively, and used for injecting different cells from each other into the cell culturing rooms, the number of the cell injection ports being the same as that of the cell culturing rooms, and a reagent injection port to inject a reagent into the cell culturing rooms.

Abstract: Provided are a carbon ion generation target and a treatment apparatus including the same. The treatment apparatus includes a support member, a carbon ion generation target fixed to the support member, and a laser for irradiating laser beam into the carbon ion generation target to generate carbon ions from the carbon ion generation target, thereby projecting the carbon ions onto a tumor portion of a patient. Here, the carbon ion generation target includes a substrate and carbon thin films disposed on the substrate.

Abstract: Provided are a microfluidic device and a microfluidic analysis equipment. The microfluidic device includes guides disposed along both edges, a lower plate including a flow path defined between the guides, and a movable upper plate moved along the guides on the lower plate and having a length less than that the flow path. A fluid flow can be simply accurately controlled by adjusting a position of the movable upper plate. As a result, the fluid can sufficiently react in the detection part and the reaction part. Therefore, effective reaction and detection can be realized using only a small amount of fluid, thereby improving sensitivity. In addition, due to the improved sensitivity, a washing process for removing materials that are not consumed in the reaction can be omitted. Also, the movable upper plate can be manually moved using a user's finger.

Abstract: Provided is a method of manufacturing a hollow microneedle structure. The method includes coating a hollow core having a predetermined section and being long in a lengthwise direction with a coating solution, and solidifying the coating solution to form a coating layer, depositing a metal seed layer on the coating layer, plating the seed metal layer with a metal to form a plated layer, cutting the hollow core having the plated layer at an inclination angle with respect to the lengthwise direction for form a surface inclination, and removing the hollow core and the coating layer to form a hollow microneedle structure. Thus, the hollow microneedle structure can be manufactured to have such diameter, length, hardness, and inclination angle as to minimize pain. By use of the hollow core, the microneedle structure can have vertical microneedles with a uniform inner diameter.

Abstract: Provided is a lab-on-a-chip. The lab-on-a-chip includes a first region where a lower substrate and an upper substrate are bonded to each other, a second region where the lower and upper substrates are not bonded, and a gap adjusting member disposed at an end of the second region that is opposite to a boundary between the first and second regions, the gap adjusting member being configured to adjust a gap between the first and second substrates to control a capillary force.

Abstract: Provided are a multiple separation device and a method of separating cancer cells in blood using the device. In this device and method, twice magnetophoresis separation steps are performed. At a second magnetophoresis separation step, shapes of ferromagnetic patterns are changed to separate cancer cells into cancer kinds.

Abstract: Provided are a multiple analysis device and a method of analyzing cancer cells in blood using the device. In this device and method, it can analyze the cancer cells along cancer kinds by using the magnetic nanoparticles combined to the markers of the cancer cells and the difference of the magnetic fields of them.

Abstract: In the present invention, a nanoporous membrane having a columnar structure is manufactured through a deposition technology used in a semiconductor process, and the size of a nanopore is adjusted by etching the lower surface of the manufactured nanoporous membrane or using a seed layer and a nanobead layer so that scaling up is available at a lowered process temperature and the size of the nanopore can be easily adjusted when manufacturing the nanoporous membrane having a columnar structure.

Abstract: Disclosed is a microfluidic control device which may electrochemically and simply measure the value of glycosylated hemoglobin in blood on a chip, a method for manufacturing the same, and a method for operating the same.

Abstract: Provided are a carbon ion generating device and a tumor treatment apparatus using the same. The carbon ion generating device includes a carbon nanostructure, a carbon emitting structure, an ionizing structure, and an accelerator. The carbon emitting structure is configured to induce an emission of carbon atoms from one end of the carbon nanostructure. The ionizing structure is configured to ionize the emitted carbon atoms. The accelerator is configured to accelerate the ionized carbon atoms.

Abstract: A method for measuring the size of microparticles includes: measuring an extinction spectrum of a medium having microparticles dispersed therein; and calculating average size of the microparticles based on the measured extinction spectrum and the Mie scattering theory.

Abstract: The present invention relates to a portable digital reader for reading an analysis target chip including a plurality of test areas. The reader comprises: a light emitting section having light emitting elements for radiating light; an integral optical splitter for uniformly distributing the light from the light emitting section to each test area of the analysis target chip; a light receiving section for receiving light reflected from each test area so as to convert the same into electric signals; and a measuring section for measuring concentration according to the electric signals obtained from the light receiving section. Therefore, it is possible to prevent the generation of errors in signal measurement due to optical distribution failure by assembling branch sections of the optical splitter under the control of the number of the branch sections according to the number of test items in a test strip.

Abstract: The present invention relates to a portable digital reader for urinalysis. The portable digital reader for reading an analysis target chip including a plurality of test areas, comprises: a main body including a light emitting section having light emitting elements for radiating light, an integral optical splitter for uniformly distributing the light from the light emitting section to each test area of the analysis target chip, a light receiving section for receiving light reflected from the each test area so as to convert the same to electric signals, and a measuring section for measuring concentration according to the electric signals obtained from the light receiving section; a main supporting body having the analysis target chip and assembled with the main body; and an auxiliary supporting body assembled between the analysis target chip and the main supporting body, including a groove for assembling the analysis target chip, and assembled with the main supporting body to be exchanged after use.

Abstract: Provided is a method of manufacturing a hollow microneedle structure. The method includes forming an injection mold having a through hole, filling the injection mold with a photoresist formed of a viscous material, and extruding the photoresist from the injection mold through the through hole, solidifying the extruded photoresist to form a needle-type photoresist structure, forming a seed layer on the surface of the photoresist structure, forming a metal plated layer on the seed layer, inclining an end tip of the photoresist structure having the metal plated layer, and removing the photoresist from the metal plated layer to form a hollow. Thus, the hollow microneedle structure can be manufactured to have such diameter, length, hardness, and inclination angle as to minimize pain. The hollow microneedle structure can be combined with an apparatus for detecting a biomaterial or injecting cosmetic substances or medicines, and variously applied.

Abstract: A treatment apparatus using proton includes a proton generation unit and a magnet. The proton generation unit projects proton into a tumor site of a patient, and the magnet forms a magnetic field around the patient. The proton conducts a spiral motion due to collision with atom of the tumor site and Lorenz force generated by the magnetic field.

Abstract: Provided are a cell culture compartment unit and an array including the same. The cell culture compartment unit includes: a cell culture region and a bio material emission region including a cell culture fluid, which are separated with a porous membrane therebetween; a piezoelectric device on the porous membrane of the cell culture region; a thin layer for cell attachment being on the piezoelectric device and having at least one surface on which cells are attachable; and a first power supply applying a first electric field to the piezoelectric device.

Abstract: Provided is a disposable multi-layered filtration device for the separation of blood plasma which can be applied to a biochip and appropriate for disposal uses. The filtration device for the separation of blood plasma includes: an upper substrate including a blood inlet; an intermediate substrate including a filtering unit for extracting blood plasma from blood flowing through the blood inlet; and a lower substrate including an air outlet, wherein the upper substrate, the intermediate substrate, and the lower substrate are stacked and adhered.

Abstract: Provided are a plastic microfluid control device having a multi-step microchannel and a method of manufacturing the same. The device includes a lower substrate, and a fluid channel substrate contacting the lower substrate and having a multi-step microchannel having at least two depths in a side coupling to the lower substrate. Thus, the device can precisely control the fluid flow by controlling capillary force in a depth direction of the channel by controlling the fluid using the multi-step microchannel having various channel depths. A multi-step micropattern is formed by repeating photolithography and transferred, thereby easily forming the multi-step microchannel having an even surface and a precisely controlled height.

Abstract: A treatment apparatus using proton includes a proton generation unit and a magnet. The proton generation unit projects proton into a tumor site of a patient, and the magnet forms a magnetic field around the patient. The proton conducts a spiral motion due to collision with atom of the tumor site and Lorenz force generated by the magnetic field.