Abstract: A balloon catheter includes a shaft and a balloon having one or more fold lines. The balloon is disposed outside the shaft, and the balloon includes one or more first regions and one or more second regions. The first region retains medicine on an outer surface of the balloon. The second region retains less medicine than the first region or retains no medicine.

Abstract: A balloon catheter includes a shaft, and a balloon provided outside the shaft. A drug is provided on an outer surface of the balloon, and the balloon has at least a straight tube part. A change ratio of an outer diameter of the straight tube part, (D28?D24)/D24, is 1.1% or less. D24 is the outer diameter of the straight tube part when an internal pressure of 2.43 MPa (24 atm) is applied, and D28 is the outer diameter of the straight tube part when an internal pressure of 2.84 MPa (28 atm) is applied.

Abstract: A balloon catheter includes a shaft and a balloon having one or more fold lines. The balloon is disposed outside the shaft, and the balloon includes one or more first regions and one or more second regions. The first region retains medicine on an outer surface of the balloon. The second region retains less medicine than the first region or retains no medicine.

Abstract: A balloon catheter includes a shaft, and a balloon provided outside the shaft. A drug is provided on an outer surface of the balloon, and the balloon has at least a straight tube part. A change ratio of an outer diameter of the straight tube part, (D28?D24)/D24, is 1.1% or less. D24 is the outer diameter of the straight tube part when an internal pressure of 2.43 MPa (24 atm) is applied, and D28 is the outer diameter of the straight tube part when an internal pressure of 2.84 MPa (28 atm) is applied.

Abstract: A biosensor comprising: an electrically insulating base plate; an electrode system comprising a working electrode and a counter electrode formed on the base plate; a cover member which is joined to the base plate to form a sample solution supply pathway for supplying a sample solution to the electrode system between the cover member and the base plate; and a reagent system comprising at least an oxidoreductase and an electron mediator disposed in the sample solution supply pathway, wherein the electron mediator is provided on the base plate and the oxidoreductase is provided on the cover member such that the electron mediator and the oxidoreductase are not in contact with each other.

Abstract: A biosensor that is highly responsive and capable of rapid and highly sensitive quantification of a specific component contained in a sample is provided. The biosensor of this invention comprises: an electrically insulating base plate; an electrode system comprising a working electrode and a counter electrode disposed on the base plate; and a reagent system comprising an oxidoreductase which catalyzes the oxidation reaction of glucose, gluconolactonase and a buffer. The buffer is selected from the group consisting of phthalic acid and its salts, maleic acid and its salts, succinic acid and its salts, phospholic acid and its salts, acetic acid and its salts, boric acid and its salts, citric acid and its salts, glycine, tris(hydroxymethyl)aminomethane, piperazine-N,N?-bis(2-ethane sulfonic acid) and the like.

Abstract: The present invention provides a high-performance glucose sensor having excellent storage stability and an improved response characteristic. This sensor comprises: an electrically insulating base plate; an electrode system including at least a working electrode and a counter electrode formed on the base plate; and a reaction layer containing at least pyrrolo-quinoline quinone dependent glucose dehydrogenase, formed in contact with or in the vicinity of the electrode system, and the reaction layer contains at least one kind of additive selected from the group consisting of gluconic acid and salts thereof.

Abstract: A sensor including an insulating base plate; an electrode system, provided on the base plate, having a measuring electrode and a counter electrode; a reaction layer including at least an oxidoreductase and an electron mediator; a sample solution supply pathway including the electrode system and the reaction layer; and a sample supply unit, wherein the sensor is so structured that, between the sample supply unit and the sample solution supply pathway, there is provided a filter having a function to filter out hemocytes and having a cross-sectional area larger than an opening of the sample solution supply pathway, and that plasma of a blood with hemocytes thereof having been filtered out is sucked into the inside of the sample solution supply pathway owing to capillary phenomena.

Abstract: A dosage determination supporting apparatus, which is able to precisely determine a dosage in accordance with the health condition of a user, is provided with: a sensor (28) for measuring the blood sugar level obtained from the blood of the user; a memory (48) for storing an operation table showing a correspondence between the blood sugar level and the amount of insulin; a CPU (50) for calculating the amount of insulin corresponding to the blood sugar level, with reference to the operation table stored in the memory (48); a displaying unit (34) for displaying the amount of insulin; and a voice processing unit (52) for performing the voice processing on the amount of insulin and outputting the voice through a speaker (32).

Abstract: In order to provide a biosensor with high accuracy and excellent response where plasma obtained by filtration of blood rapidly arrives at an electrode system, in a biosensor comprising: an insulating base plate; an electrode system having a working electrode and a counter electrode which are provided on the base plate; a reaction layer including at least oxidoreductase and an electron mediator; a sample solution supply pathway which includes the electrode system and the reaction layer and has an inlet and an air aperture; a sample solution supply part for introducing a sample solution, which is in position apart from the sample solution supply pathway; and a first filter which is disposed between the sample solution supply pathway and the sample solution supply part for filtering the sample solution, where the filtrate filtered with the first filter is supplied into the sample solution supply pathway due to capillary action, the direction in which the sample solution passes through the first filter and the di

Abstract: A lancet device is provided capable of taking a sufficient amount of body fluid with less pain or readily healing wounds formed in the skin.

Abstract: Disclosed is a highly responsive biosensor comprising a cholesterol-oxidizing enzyme and cholesterol esterase. The biosensor comprises: an electrically insulating base plate; an electrode system including a working electrode and a counter electrode formed on the base plate; a cover member joined with the base plate to define a sample supply pathway through which a sample solution is introduced from a sample supply port to the electrode system, the sample supply pathway being formed between the cover member and the base plate; and a reagent layer formed in the sample supply pathway, wherein the reagent layer contains a cholesterol-oxidizing enzyme, cholesterol esterase, an electron mediator, and a buffer having a buffering capacity in an acidic pH range.

Abstract: The present invention provides a biosensor that enables highly-accurate measurement of a sample solution including a solid component like hemocytes and has a little variation in response. The biosensor includes: an insulating base plate, an electrode system having at least a working electrode and a counter electrode provided on the base plate, a cover member that is combined with the base plate to define a sample solution supply pathway for leading a sample solution from a sample supply unit to the electrode system, a reaction reagent system including at least an oxidation-reduction enzyme and an electron mediator, and a filter disposed between the electrode system and the sample supply unit in the sample solution supply pathway. The biosensor has a space that encircles surface of the filter in an area from one end of the filter close to the sample supply unit to the other end of the filter close to the electrode system.

Abstract: There is provided: a sensor capable of accurately and simply measuring LDL cholesterol by only a one-time supply of a sample; and a method of the above measurement. The biosensor is constituted such that cholesterol esterase, cholesterol oxidase or cholesterol dehydrogenase, a reagent for bringing a selective enzyme reaction with LDL, peroxidase, and a dye source, are carried on a substrate.

Abstract: The present disclosure relates to a method for determining cholesterol in low density lipoprotein comprising the steps of (a) measuring total cholesterol level in a sample containing at least high density lipoprotein, low density lipoprotein, very low density lipoprotein and chylomicron, and (b) measuring cholesterol levels in the high density lipoprotein, very low density lipoprotein and chylomicron in the sample, wherein the cholesterol level in the low density lipoprotein is determined by subtracting a value obtained in the step (b) from a value obtained in the step (a). The present invention enables concurrent determination of cholesterol level in low density lipoprotein and total cholesterol level, facilitating acquisition of two types of biological information at a time.

Abstract: A biosensor comprising an electrically insulating base plate, an electrode system containing a working electrode and a counter electrode disposed on the base plate, and a reagent system comprising at least an oxidoreductase, a hydrophilic polymer and an electron mediator, wherein the reagent system further comprises a substance having a function to convert an organic product generated by direct reaction of a substrate to be measured with the oxidoreductase to another compound.

Abstract: A biosensor comprising: an electrically insulating base plate; an electrode system comprising a working electrode and a counter electrode formed on the base plate; a cover member which is joined to the base plate to form a sample solution supply pathway for supplying a sample solution to the electrode system between the cover member and the base plate; and a reagent system comprising at least an oxidoreductase and an electron mediator disposed in the sample solution supply pathway, wherein the electron mediator is provided on the base plate and the oxidoreductase is provided on the cover member such that the electron mediator and the oxidoreductase are not in contact with each other.

Abstract: A biosensor includes: an insulating base plate; an electrode system which is provided on the base plate and has a measurement electrode and a counter electrode; a reaction layer including at least oxidoreductase and an electron mediator; a sample solution supply pathway which includes the electrode system and the reaction layer and has an air aperture on the termination side thereof; a sample supply portion; and a filter which is disposed between the sample solution supply pathway and the sample supply portion and filters hemocytes, where plasma with the hemocytes therein filtered with the filter is sucked into the sample solution supply pathway due to capillarity, the central part of a secondary side portion of the filter is protruded into the sample solution supply pathway more than both the right and left ends thereof.

Abstract: There is provided a cholesterol sensor with high-accuracy and excellent response, whose object to be measured is whole blood, where plasma with hemocytes therein filtered can rapidly reach an electrode system. In a biosensor where plasma with hemocytes therein filtered with a filter is sucked into a sample solution supply pathway due to capillarity, there are formed: a first pressing part for holding a primary side portion of the filter from the bottom; a second pressing part for holding a secondary side portion of the filter from the top and the bottom; a third pressing part for holding the central portion of the filter from the top; and a void for surrounding the filter between the second pressing part and third pressing part.

Abstract: There is provided a cholesterol sensor with high-accuracy and excellent response, whose object to be measured is whole blood, where plasma with which is obtained by filtering out hemocytes therein filtered in blood can rapidly reach an electrode system. In a biosensor where plasma with which is obtained by filtering out hemocytes therein filtered with by a filter is sucked into a sample solution supply pathway due to capillarity, there are formed: a first pressing part for holding a primary side portion of the filter from the bottom; a second pressing part for holding a secondary side portion of the filter from the top and the bottom; a third pressing part for holding the central portion of the filter from the top; and a void for surrounding the filter between the second pressing part and third pressing part.