Abstract: A compound represented by general formula (I) (wherein all symbols are as defined in the description) or a salt, solvate, N-oxide form or prodrug thereof is a potent FXIa inhibitor, has excellent oral absorption properties and kinetics in blood, can exert a potent anti-coagulation activity over a long period of time after being administered orally, and has a discrepancy between the anti-coagulation activity thereof and the CYP-inhibiting activity thereof. Therefore, the compound or the salt, solvate, N-oxide form or prodrug thereof can be used as an efficient prophylactic and/or therapeutic agent for vascular occlusive diseases.

Abstract: A light source includes: a mounting substrate; and a side-view type light-emitting device including: a substrate; through holes; a front electrode; a rear electrode; side electrodes; and a light-emitting element, wherein: land patterns are formed on a front surface of the mounting substrate, in positions corresponding to the through holes, each land pattern having an inverted “T” shape composed of a narrow region and a wide region; the light-emitting device is arranged such that the cross sectional shape of the through hole in the long side direction of the substrate is aligned with the shape of the narrow region of the land pattern, in a plan view; and solder members are formed in a wall shape on the mounting substrate, are formed in the through holes on the mounting substrate, and connects the rear electrode and the side electrode to the wide region and the narrow region, respectively.

Abstract: A light source includes: a mounting substrate; and a side-view type light-emitting device including: a substrate; through holes; a front electrode; a rear electrode; side electrodes; and a light-emitting element, wherein: land patterns are formed on a front surface of the mounting substrate, in positions corresponding to the through holes, each land pattern having an inverted “T” shape composed of a narrow region and a wide region; the light-emitting device is arranged such that the cross sectional shape of the through hole in the long side direction of the substrate is aligned with the shape of the narrow region of the land pattern, in a plan view; and solder members are formed in a wall shape on the mounting substrate, are formed in the through holes on the mounting substrate, and connects the rear electrode and the side electrode to the wide region and the narrow region, respectively.

Abstract: To suppress misalignment when a light-emitting element is mounted on a substrate. On the substrate of a light-emitting device, a through hole is formed passing through so as to notch the side surface of the substrate, and a side surface electrode is formed on the side surface of the through hole. The pattern of a front surface electrode has a first region, a second region being connected to the first region, and a third region being connected to the first region and the second region. The shape of the first region is a rectangle coinciding with the electrode of the light-emitting element, and the longitudinal direction of the rectangle is aligned with the longitudinal direction of the substrate. The second region is formed in a lid shape so as to cover the top of the through hole. The shape of the second region is a trapezoid.

Abstract: A method of manufacturing a light emitting device includes injecting liquid or pasty transparent resin into a sheet forming mold, adding a phosphor to the resin in the mold, centrifugally rotating the mold so as to settle the phosphor included in the resin toward one surface side of the resin, thermally curing the resin so as to form a phosphor sheet, the phosphor sheet including a phosphor layer formed on the one surface side of the resin and a transparent layer formed on an other surface side of the resin, overlaying the phosphor sheet on a light emitting element such that the phosphor layer of the phosphor sheet contacts with a light emitting surface of the light emitting element, mounting the light emitting element with the phosphor sheet overlaid on a board, and flattening a surface of the transparent layer of the phosphor sheet on the light emitting element.

Abstract: A compound represented by general formula (I) (wherein all symbols are as defined in the description) or a salt, solvate, N-oxide form or prodrug thereof is a potent FXIa inhibitor, has excellent oral absorption properties and kinetics in blood, can exert a potent anti-coagulation activity over a long period of time after being administered orally, and has a discrepancy between the anti-coagulation activity thereof and the CYP-inhibiting activity thereof. Therefore, the compound or the salt, solvate, N-oxide form or prodrug thereof can be used as an efficient prophylactic and/or therapeutic agent for vascular occlusive diseases.

Abstract: A method of manufacturing a light emitting device includes injecting liquid or pasty transparent resin into a sheet forming mold, adding a phosphor to the resin in the mold, centrifugally rotating the mold so as to settle the phosphor included in the resin toward one surface side of the resin, thermally curing the resin so as to form a phosphor sheet, the phosphor sheet including a phosphor layer formed on the one surface side of the resin and a transparent layer formed on an other surface side of the resin, overlaying the phosphor sheet on a light emitting element such that the phosphor layer of the phosphor sheet contacts with a light emitting surface of the light emitting element, mounting the light emitting element with the phosphor sheet overlaid on a board, and flattening a surface of the transparent layer of the phosphor sheet on the light emitting element.

Abstract: A method of manufacturing a light emitting element includes forming a resin film including a phosphor containing layer on a transparent board side surface of a wafer including a transparent board and a plurality of light emitting parts formed on the transparent board, forming a scribing line along a scheduled separation surface in a surface of the transparent board by scribing before or after forming the resin film, cutting the resin film along the scheduled separation surface before or after forming the scribing line, and separating the transparent board along the scheduled separation surface by breaking after forming the scribing line and cutting the resin film.

Abstract: A side view type surface mounted light-emitting device includes a submount substrate that includes a mounting surface on one side surface and end through-holes formed at both edges of the mounting surface, a light-emitting element mounted on the submount substrate, first and second flat terminals formed on the mounting surface, and first and second through-hole terminals respectively formed on inner surfaces of the end through-holes at both edges of the mounting surface. At least one of the first flat terminal and the first through-hole terminal is electrically connected to one of n-side and p-side electrodes of the light-emitting element, and at least one of the second flat terminal and the second through-hole terminal is electrically connected to the other of the n-side and p-side electrodes of the light-emitting element.

Abstract: A manufacturing method of a side view type light emitting device including a package body made of a synthetic resin material, the manufacturing method includes: providing an injection molding mold, for injection-molding the package body, including: a first mold provided with a first convex part for forming an upper surface side flat part on an upper surface of the package body; and a second mold provided with a first concave part for forming the upper surface side flat part; and fitting the first concave part around the first convex part so as to enter a liquid tight state with no space, injecting the synthetic resin material into each of the first and second molds so as to be filled therein, and hardening the synthetic resin material to form the package body in a state in which the first mold and the second mold are aligned with each other.

Abstract: A vehicle-body front structure that is able to secure collision performance for a collision with a small overlap amount of a collision object with respect to a bumper frame portion is obtained. A vehicle-body front structure includes: paired frame members elongated in a vehicle front-rear direction and arranged side by side in a vehicle width direction; a bumper frame portion elongated in the vehicle width direction and provided over front ends of the paired frame members in the vehicle front-rear direction; and a load transmission member. The load transmission member is placed on an inner side in the vehicle width direction relative to at least one of the frame members so as to be opposed to a load receiving portion placed between the paired frame members from at least one of a front side in the vehicle front-rear direction and an outer side in the vehicle width direction within a range where the load transmission member overlaps with the frame member in a vehicle up-down direction.

Abstract: The disclosed device includes: housing which has opening; protective panel arranged in the housing and which closes opening; O ring which is arranged on one face of protective panel in a direction perpendicular to an opening plane of opening; sliding plate which is arranged on the other face of protective panel in a direction perpendicular to the opening plane of opening and which holds protective panel in such a way that protective panel can slide in a direction parallel to the opening plane of opening; and spring member which is arranged in the state of making contact with an end portion of protective panel and which supports protective panel in such a way that protective panel can be displaced in a direction parallel to the opening plane of opening. Protective panel is supported by housing in the state in which protective panel is sandwiched between O ring and sliding plate.

Abstract: A vehicle-body front structure that is able to secure collision performance for a collision with a small overlap amount of a collision object with respect to a bumper frame portion is obtained. A vehicle-body front structure includes: paired frame members elongated in a vehicle front-rear direction and arranged side by side in a vehicle width direction; a bumper frame portion elongated in the vehicle width direction and provided over front ends of the paired frame members in the vehicle front-rear direction; and a load transmission member. The load transmission member is placed on an inner side in the vehicle width direction relative to at least one of the frame members so as to be opposed to a load receiving portion placed between the paired frame members from at least one of a front side in the vehicle front-rear direction and an outer side in the vehicle width direction within a range where the load transmission member overlaps with the frame member in a vehicle up-down direction.

Abstract: In a vehicle front structure, a spacer protruding outwardly in a vehicle width direction from a front end of a side rail portion of a suspension member is extended toward a vehicle-width outer side relative to a front side member. Accordingly, when a vehicle has a short overlap collision with a barrier, it is possible to disperse a collision load from the barrier to the suspension member via the spacer. Besides, since the side rail portion of the suspension member is placed on the vehicle-width outer side relative to the power unit, it is possible to disperse the collision load to a power-unit side via the suspension member.

Abstract: The present invention relates to a compound represented by formula (I): wherein all symbols are as defined here, a salt thereof, a solvate thereof, or a prodrug thereof. The compound of the present invention has an antagonistic activity against CXCR4 and is therefore useful as a preventive and/or therapeutic agent for CXCR4-mediated diseases, for example, inflammatory and immune diseases (for example, rheumatoid arthritis, arthritis, retinopathy, pulmonary fibrosis, rejection of transplanted organ, etc.), allergic diseases, infections (for example, human immunodeficiency virus infection, acquired immunodeficiency syndrome, etc.), psychoneurotic diseases, cerebral diseases, cardiovascular disease, metabolic diseases, and cancerous diseases (for example, cancer, cancer metastasis, etc.), or an agent for regeneration therapy.

Abstract: The present invention relates to a compound represented by formula (I): wherein all symbols are as defined here, a salt thereof, a solvate thereof, or a prodrug thereof. The compound of the present invention has an antagonistic activity against CXCR4 and is therefore useful as a preventive and/or therapeutic agent for CXCR4-mediated diseases, for example, inflammatory and immune diseases (for example, rheumatoid arthritis, arthritis, retinopathy, pulmonary fibrosis, rejection of transplanted organ, etc.), allergic diseases, infections (for example, human immunodeficiency virus infection, acquired immunodeficiency syndrome, etc.), psychoneurotic diseases, cerebral diseases, cardiovascular disease, metabolic diseases, and cancerous diseases (for example, cancer, cancer metastasis, etc.), or an agent for regeneration therapy.

Abstract: The present invention relates to a compound represented by formula (I): wherein all symbols are as defined here, a salt thereof, a solvate thereof, or a prodrug thereof. The compound of the present invention has an antagonistic activity against CXCR4 and is therefore useful as a preventive and/or therapeutic agent for CXCR4-mediated diseases, for example, inflammatory and immune diseases (for example, rheumatoid arthritis, arthritis, retinopathy, pulmonary fibrosis, rejection of transplanted organ, etc.), allergic diseases, infections (for example, human immunodeficiency virus infection, acquired immunodeficiency syndrome, etc.), psychoneurotic diseases, cerebral diseases, cardiovascular disease, metabolic diseases, and cancerous diseases (for example, cancer, cancer metastasis, etc.), or an agent for regeneration therapy.

Abstract: The disclosed device includes: housing which has opening; protective panel arranged in the housing and which closes opening; O ring which is arranged on one face of protective panel in a direction perpendicular to an opening plane of opening; sliding plate which is arranged on the other face of protective panel in a direction perpendicular to the opening plane of opening and which holds protective panel in such a way that protective panel can slide in a direction parallel to the opening plane of opening; and spring member which is arranged in the state of making contact with an end portion of protective panel and which supports protective panel in such a way that protective panel can be displaced in a direction parallel to the opening plane of opening. Protective panel is supported by housing in the state in which protective panel is sandwiched between O ring and sliding plate.