Abstract: Implantable biocompatible polymeric medical devices include a substrate with an acid or base-modified surface which is subsequently modified to include click reactive members.

Abstract: Implantable biocompatible polymeric medical devices include a substrate with an acid or base-modified surface which is subsequently modified to include click reactive members.

Abstract: Implantable biocompatible polymeric medical devices include a substrate with an acid or base-modified surface which is subsequently modified to include click reactive members.

Abstract: Implantable biocompatible polymeric medical devices include a substrate with a plasma-modified surface which is subsequently modified to include click reactive members.

Abstract: Implantable biocompatible polymeric medical devices include a substrate with an acid or base-modified surface which is subsequently modified to include click reactive members.

Abstract: A composite fixation device is described herein which includes a first and second biodegradable material. The first and second biodegradable materials degrade at different rates thereby permitting tissue ingrowth into the device prior to degradation of the entire device.

Abstract: The present disclosure relates to an apparatus and process for forming medical devices from an injectable composition. The apparatus includes a supply assembly, a mixing assembly, and at least one source of microwave energy. The supply assembly is configured to maintain and selectively dispense a first precursor functionalized with a first reactive member and a second precursor functionalized with a second reactive member. The mixing assembly is configured to mix the first and second precursors within a mixing cavity defined therein. The microwave energy source is configured and adapted to irradiate the mixed first and second precursors within the mixing cavity.

Abstract: Novel biodegradable phosphoester polyamines are disclosed. The biodegradable phosphoester polyamines may be utilized as cross-linkers for sprayable compositions which may be used as tissue adhesives or sealants.

Abstract: Implantable biocompatible polymeric medical devices include a substrate with an acid or base-modified surface which is subsequently modified to include click reactive members.

Abstract: Implantable biocompatible polymeric medical devices include a substrate with an acid or base-modified surface which is subsequently modified to include click reactive members.

Abstract: A composite fixation device is described herein which includes a first and second biodegradable material. The first and second biodegradable materials degrade at different rates thereby permitting tissue ingrowth into the device prior to degradation of the entire device.

Abstract: A composite fixation device is described herein which includes a first and second biodegradable material. The first and second biodegradable materials degrade at different rates thereby permitting tissue ingrowth into the device prior to degradation of the entire device.

Abstract: Biocompatible macromer compositions are provided including an isocyanate-functional polyalkylene oxide combined with at least one multi-functional isocyanate as a first component, and a multi-amino functional compound possessing multiple primary amines as a second component. The isocyanate-functional polyalkylene oxide has pendant polyalkylene oxide groups. The resulting biocompatible macromer composition can be employed as an adhesive or sealant for medical/surgical uses.

Abstract: Methods for producing biocompatible compositions are provided. The biocompatible compositions include an aliphatic polyester macromer produced without the use of solvents or catalysts. The resulting aliphatic polyester macromer may be reacted with a polyisocyanate to form an end-capped aliphatic polyester macromer which, in turn, may be reacted with a polyol to produce a polyurethane. The polyurethane, in turn, may be reacted with a second polyisocyanate to produce an isocyanate-functional polyurethane. The compositions prepared by the methods of the present disclosure may be used as adhesives or sealants for medical/surgical uses.

Abstract: Novel biodegradable phosphoester polyamines are disclosed. The biodegradable phosphoester polyamines may be utilized as cross-linkers for sprayable compositions which may be used as tissue adhesives or sealants.

Abstract: Packaging materials for medical devices are provided. The packaging is formed of a biodegradable material which permits disposal by conventional methods, including landfills, composting, and the like. Use of the packaging avoids undesirable disposal methods such as incineration and the like.

Abstract: Novel biodegradable phosphoester polyamines are disclosed. The biodegradable phosphoester polyamines may be utilized as cross-linkers for sprayable compositions which may be used as tissue adhesives or sealants.

Abstract: The present disclosure relates to an apparatus and process for forming medical devices from an injectable composition. The apparatus includes a supply assembly, a mixing assembly, and at least one source of microwave energy. The supply assembly is configured to maintain and selectively dispense a first precursor functionalized with a first reactive member and a second precursor functionalized with a second reactive member. The mixing assembly is configured to mix the first and second precursors within a mixing cavity defined therein. The microwave energy source is configured and adapted to irradiate the mixed first and second precursors within the mixing cavity.

Abstract: An implantable orthopedic medical device is disclosed. The medical devices is formed from a biodegradable polymer stereocomplex comprising a biodegradable polymer including a first enantiomer and a second enantiomer, wherein the implantable medical device initially degrades at a first degradation rate and subsequently degrades at a second degradation rate that is faster than the first degradation rate.

Abstract: Biocompatible macromer compositions are provided including an isocyanate-functional polyalkylene oxide combined with at least one multi-functional isocyanate as a first component, and a multi-amino functional compound possessing multiple primary amines as a second component. The isocyanate-functional polyalkylene oxide has pendant polyalkylene oxide groups. The resulting biocompatible macromer composition can be employed as an adhesive or sealant for medical/surgical uses.