Patents by Inventor Nan-Horng Lin

Nan-Horng Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Filamin A binding anti-inflammatory and analgesic
    Patent number: 8653068
    Abstract: A compound or its pharmaceutically acceptable salt, composition and method are disclosed that can provide analgesia and reduce inflammation. A contemplated compound has a structure that corresponds to Formula A, wherein the R group substituents, d, e, f, k, n, m, D, E, F, K, G, P, Q, W, and Z are defined within.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: February 18, 2014
    Assignee: Pain Therapeutics, Inc.
    Inventors: Lindsay Burns Barbier, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • Filamin A binding anti-inflammatory and analgesic
    Patent number: 8614324
    Abstract: A compound or its pharmaceutically acceptable salt, optionally including both individual enantiomeric forms, a racemate, diastereomers and mixtures thereof, composition and method are disclosed that can provide analgesia and reduce inflammation. A contemplated compound has a structure that corresponds to Formula A, wherein the R group substituents, d, e, f, k, n, m, D, E, F, K, G, P, Q, W, and Z are defined within.
    Type: Grant
    Filed: March 8, 2010
    Date of Patent: December 24, 2013
    Assignee: Pain Therapeutics, Inc.
    Inventors: Lindsay Burns Barbier, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • Filamin A-binding anti-inflammatory analgesic
    Patent number: 8580809
    Abstract: A compound, its pharmaceutically acceptable salt, a composition containing the same and method of treatment that can provide analgesia and/or reduce inflammation are disclosed. A contemplated compound has a structure that corresponds to Formula A, wherein G, W, Q, Z, D, E, F, K, Y, d, e, f, k, n, m, and circle B and all R groups are defined within.
    Type: Grant
    Filed: March 8, 2010
    Date of Patent: November 12, 2013
    Assignee: Pain Therapeutics, Inc.
    Inventors: Lindsay Burns Barbier, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • Filamin A-binding anti-inflammatory analgesic
    Patent number: 8580808
    Abstract: A compound, its pharmaceutically acceptable salt, a composition containing the same and method of treatment that can provide analgesia and/or reduce inflammation are disclosed. A contemplated compound has a structure that corresponds to Formula A, wherein G, W, Q, Z, D, E, F, K, Y, d, e, f, k, n, m, and circle B and all R groups are defined within.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: November 12, 2013
    Assignee: Pain Therapeutic, Inc.
    Inventors: Lindsay Burns Barbier, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • Substituted thieno[3,2-d]pyrimidine PIM kinase inhibitors as cancer chemotherapeutics
    Patent number: 8148384
    Abstract: Compounds of formula I wherein A1, A2, and A3 are as defined herein are inhibitors of PIM kinase. The compounds of formula I are useful for the treatment of diseases such as cancer.
    Type: Grant
    Filed: December 6, 2007
    Date of Patent: April 3, 2012
    Assignee: Abbott Laboratories
    Inventors: Thomas D. Penning, Lisa A. Hasvold, Laura A. Hexamer, Vincent L. Giranda, Nan-horng Lin, Zhi-Fu Tao, Le Wang
  • Cyclobut-3-ene-1,2,-dione inhibitors of polo-like kinases
    Patent number: 7956185
    Abstract: Compounds of formula (I) where X1, C1, and D1 are defined herein, are inhibitors of polo-like kinases. The compounds of formula (I) are useful for treatment of diseases of cellular proliferation, such as, for example, cancer.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: June 7, 2011
    Assignee: Abbott Laboratories
    Inventors: Robert B. Diebold, Stevan W. Djuric, Vincent L. Giranda, Laura A. Hexamer, Nan-Horng Lin, Julie M. Miyashiro, Thomas D. Penning, Magdalena Przytulinska, Thomas J. Sowin, Gerard M. Sullivan, Zhi-Fu Tao, Yunsong Tong, Anil Vasudevan, Le Wang, Keith W. Woods, Zhiren Xia, Henry Q. Zhang
  • FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC
    Publication number: 20110105487
    Abstract: A compound or its pharmaceutically acceptable salt, composition and method are disclosed that can provide analgesia and reduce inflammation. A contemplated compound has a structure that corresponds to Formula A, wherein the R group substituents, d, e, f, k, n, m, D, E, F, K, G, P, Q, W, and Z are defined within.
    Type: Application
    Filed: October 30, 2009
    Publication date: May 5, 2011
    Inventors: LINDSAY BURNS BARBIER, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • FILAMIN A-BINDING ANTI-INFLAMMATORY ANALGESIC
    Publication number: 20110105547
    Abstract: A compound, its pharmaceutically acceptable salt, a composition containing the same and method of treatment that can provide analgesia and/or reduce inflammation are disclosed. A contemplated compound has a structure that corresponds to Formula A, wherein G, W, Q, Z, D, E, F, K, Y, d, e, f, k, n, m, and circle B and all R groups are defined within.
    Type: Application
    Filed: March 8, 2010
    Publication date: May 5, 2011
    Inventors: Lindsay Burns Barbier, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC
    Publication number: 20110105481
    Abstract: A compound or its pharmaceutically acceptable salt, optionally including both individual enantiomeric forms, a racemate, diastereomers and mixtures thereof, composition and method are disclosed that can provide analgesia and reduce inflammation. A contemplated compound has a structure that corresponds to Formula A, wherein the R group substituents, d, e, f, k, n, m, D, E, F, K, G, P, Q, W, and Z are defined within.
    Type: Application
    Filed: March 8, 2010
    Publication date: May 5, 2011
    Inventors: Lindsay Burns Barbier, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • FILAMIN A-BINDING ANTI-INFLAMMATORY ANALGESIC
    Publication number: 20110105484
    Abstract: A compound, its pharmaceutically acceptable salt, a composition containing the same and method of treatment that can provide analgesia and/or reduce inflammation are disclosed. A contemplated compound has a structure that corresponds to Formula A, wherein G, W, Q, Z, D, E, F, K, Y, d, e, f, k, n, m, and circle B and all R groups are defined within.
    Type: Application
    Filed: October 30, 2009
    Publication date: May 5, 2011
    Inventors: Lindsay Burns Barbier, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • NOVEL ANALGESIC THAT BINDS FILAMIN A
    Publication number: 20100279996
    Abstract: A compound, composition and method are disclosed that can provide analgesia. A contemplated compound has a structure that corresponds to Formula I, wherein R1 and R2 are substituents, and W is a ring structure that are defined within.
    Type: Application
    Filed: May 4, 2009
    Publication date: November 4, 2010
    Inventors: Lindsay Burns Barbier, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • ANALGESIC THAT BINDS FILAMIN A
    Publication number: 20100279997
    Abstract: A compound, composition and method are disclosed that can provide analgesia. A contemplated compound has a structure that corresponds to Formula A, wherein A, B, X, R1, R2, R7 and R8, and the dashed lines are defined within.
    Type: Application
    Filed: October 28, 2009
    Publication date: November 4, 2010
    Inventors: Lindsay Burns Barbier, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • NOVEL ANALGESIC THAT BINDS FILAMIN A
    Publication number: 20100280061
    Abstract: A compound, composition and method are disclosed that can bind to FLNA and provide analgesia. A contemplated compound has a structure that corresponds to Formula I, wherein R1 and R2 are substituents on W that is a ring structure, R3 and R4 are substituents on the depicted nitrogen atom, m, n and the dotted lines are all defined within.
    Type: Application
    Filed: May 4, 2009
    Publication date: November 4, 2010
    Inventors: Lindsay Burns Barbier, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • NOVEL ANALGESIC THAT BINDS FILAMIN A
    Publication number: 20100280057
    Abstract: A compound, composition and method are disclosed that can provide analgesia. A contemplated compound has a structure that corresponds to Formula I, wherein R1 and R2 are substituents, and n, W, X and Y are defined within.
    Type: Application
    Filed: May 4, 2009
    Publication date: November 4, 2010
    Inventors: Lindsay Burns Barbier, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • Heterocyclic kinase inhibitors
    Patent number: 7456169
    Abstract: Compounds having the formula are useful for inhibiting protein kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: August 23, 2006
    Date of Patent: November 25, 2008
    Assignee: Abbott Laboratories Inc.
    Inventors: Lisa A. Hasvold, Laura Hexamer, Gaoquan Li, Nan-Horng Lin, Hing Sham, Thomas J. Sowin, Gerard M. Sullivan, Le Wang, Ping Xia
  • PIM KINASE INHIBITORS AS CANCER CHEMOTHERAPEUTICS
    Publication number: 20080161559
    Abstract: Inhibitors of Pim kinases, ways to make them and methods of treating patients using them are disclosed.
    Type: Application
    Filed: December 6, 2007
    Publication date: July 3, 2008
    Applicant: ABBOTT LABORATORIES
    Inventors: Thomas D. Penning, Lisa A. Hasvold, Laura A. Hexamer, Vincent L. Giranda, Nan-horng Lin, Zhi-Fu Tao, Le Wang
  • Farnesyltransferase inhibitors
    Patent number: 7323570
    Abstract: Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.
    Type: Grant
    Filed: July 25, 2006
    Date of Patent: January 29, 2008
    Assignee: Abbott Laboratories
    Inventors: Akiyo K. Claiborne, Stephen L. Gwaltney, II, Lisa A. Hasvold, Qun Li, Tongmei Li, Nan-Horng Lin, Robert A. Mantei, Todd W. Rockway, Hing L. Sham, Gerard M. Sullivan, Yunsong Tong, Gary Wang, Le Wang, Xilu Wang, Wei-Bo Wang
  • Fused tri and tetra-cyclic pyrazole kinase inhibitors
    Patent number: 7320986
    Abstract: Compounds having the formula (I) are useful for inhibiting protein kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: March 3, 2004
    Date of Patent: January 22, 2008
    Assignee: Abbott Labortories
    Inventors: Yunsong Tong, Akiyo K. Claiborne, Gaoquan Li, Nan-Horng Lin, Hing L. Sham, Thomas J. Sowin, Zhi-Fu Tao
  • INHIBITORS OF POLO-LIKE KINASES
    Publication number: 20080015192
    Abstract: Compounds that inhibit Plk1, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
    Type: Application
    Filed: May 24, 2007
    Publication date: January 17, 2008
    Inventors: Robert Diebold, Stevan Djuric, Vincent Giranda, Laura Hexamer, Nan-Horng Lin, Julie Miyashiro, Thomas Penning, Magdalena Przytulinska, Thomas Sowin, Gerard Sullivan, Zhi-Fu Tao, Yunsong Tong, Anil Vasudevan, Le Wang, Keith Woods, Zhiren Xia, Henry Zhang
  • Heterocyclic Kinase Inhibitors
    Publication number: 20070254867
    Abstract: Compounds having the formula are useful for inhibiting protein kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: August 23, 2006
    Publication date: November 1, 2007
    Inventors: Lisa Hasvold, Laura Hexamer, Gaoquan Li, Nan-Horng Lin, Hing Sham, Thomas Sowin, Gerard Sullivan, Le Wang, Ping Xia