Patents by Inventor Nan Hui

Nan Hui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF MENIN-MLL INTERACTION
    Publication number: 20240124467
    Abstract: Disclosed herein are heterocyclic compounds that inhibit the binding of menin and MLL or MLL fusion proteins. Also described are specific irreversible inhibitors of menin-MLL interaction. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the menin-MLL irreversible inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, leukemia and other diseases or conditions dependent on menin-MLL interaction.
    Type: Application
    Filed: December 16, 2021
    Publication date: April 18, 2024
    Inventors: Thomas Butler, James T. PALMER, Thorsten KIRSCHBERG, Nan-Homg LIN, Hon HUI, Ravindra UPASANI, Solomon B. UNGASHE, David SPERANDIO
  • Pleuromulin lipoic acid ester with antibacterial activity and a method of preparing the same
    Patent number: 11597714
    Abstract: A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Grant
    Filed: December 19, 2020
    Date of Patent: March 7, 2023
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan Liang, Cong Du, Qianqian Zhao, Liang Xin, Jingyi Li, Dan Yang, Nan Hui, Guaiping Qiao, Han Li, Yanjun Li, Liang Qi, Wenbo Yao, Gennian Mao
  • Pleuromulin 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid ester with antibacterial activity and a method of preparing the same
    Patent number: 11555016
    Abstract: A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. The methods of preparing the compound of formula (I) are also disclosed.
    Type: Grant
    Filed: January 25, 2021
    Date of Patent: January 17, 2023
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Yongbo Wang, Han Li, Gennian Mao, Bin Tian, Dan Yang, Chengyuan Liang, Xiuding Yang, Wenbo Yao, Guaiping Qiao, Nan Hui, Juan Li, Liang Xin, Jingyi Li, Ruina Bian
  • PLEUROMULIN 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID ESTER WITH ANTIBACTERIAL ACTIVITY AND A METHOD OF PREPARING THE SAME
    Publication number: 20220235008
    Abstract: A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. The methods of preparing the compound of formula (I) are also disclosed.
    Type: Application
    Filed: January 25, 2021
    Publication date: July 28, 2022
    Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Wenbo YAO, Guaiping QIAO, Nan HUI, Juan LI, Liang XIN, Jingyi LI, Ruina BIAN, Han LI, Gennian MAO, Bin TIAN, Dan YANG, Chengyuan LIANG
  • Lilac ginkgo brick tea and method of preparing the same
    Patent number: 11376299
    Abstract: A method of preparing a Lilac Ginkgo Brick Tea includes the following steps: (1) mixing and drying fresh Lilac leaves and Ginkgo leaves to obtain a Lilac Ginkgo Tea; (2) fermenting the Lilac Ginkgo Tea to obtain a Fermented Lilac Ginkgo Tea; (3) mixing the Fermented Lilac Ginkgo Tea with a black tea to obtain a Fermented Lilac Ginkgo Tea Mixture; and (4) processing the Fermented Lilac Ginkgo Tea Mixture to obtain the Lilac Ginkgo Brick Tea.
    Type: Grant
    Filed: October 20, 2019
    Date of Patent: July 5, 2022
    Assignee: XI'AN KANGYUANSHENG BIOMEDICAL TECHNOLOGY CO., LTD.
    Inventors: Jia Wan, Chunchun Kong, Chengyuan Liang, Nan Hui, Chunyang Shi, Han Li, Bin Tian, Gennian Mao, Qianqian Zhao, Qiao Zeng
  • PLEUROMULIN LIPOIC ACID ESTER WITH ANTIBACTERIAL ACTIVITY AND A METHOD OF PREPARING THE SAME
    Publication number: 20220194918
    Abstract: A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Application
    Filed: December 19, 2020
    Publication date: June 23, 2022
    Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Qianqian ZHAO, Liang XIN, Jingyi LI, Dan YANG, Nan HUI, Guaiping QIAO, Han LI, Yanjun LI, Liang QI, Wenbo YAO, Gennian MAO, Chengyuan LIANG
  • METHOD OF PREPARING HYDROXYTYROSOL CINNAMIC ACID ESTER WITH ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES
    Publication number: 20220089518
    Abstract: A method of preparing a compound of formula (I): is disclosed. The compound of formula (I) can be used as an antioxidant agent. The compound can also be used as an antibacterial agent to inhibit Staphylococcus aureus MRSA 18-222 and Pseudomonas aeruginosa MDR-PA 18-1774.
    Type: Application
    Filed: September 19, 2020
    Publication date: March 24, 2022
    Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Han LI, Nan HUI, Guaiping QIAO, Juan LI, Wenbo YAO, Yongbo WANG, Gennian MAO, Bin TIAN, Yanjun LI, Qiaoqiao ZHAO, Jingwen XU, Dan YANG, Chengyuan LIANG
  • Method for extracting herbal medicine
    Patent number: 11219652
    Abstract: A method for extracting herbal medicine includes: step one, spray extraction; step two, pressure filtration and concentration; step three, spray and countercurrent precipitation; and step four, concentrating reduced pressure and drying.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: January 11, 2022
    Assignee: SHAANXI PANLONG PHARMACEUTICAL GROUP LIMITED BY SHARE LTD.
    Inventors: Xiaolin Xie, Dezhu Zhang, Jianguo Meng, Yu Wang, Xuhua Zhou, Zhong Meng, Nan Hui, Juan Li
  • Pleuromutilin ursodeoxycholic acid ester with antibacterial activity and a method of preparing the same
    Patent number: 11186607
    Abstract: A compound with antibacterial activity having the following formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Grant
    Filed: December 25, 2020
    Date of Patent: November 30, 2021
    Assignee: Xi'an Taikomed Pharmaceutical Technology Co., Ltd.
    Inventors: Yonghong Tang, Bin Tian, Lei Tian, Yanjun Li, Qiao Zeng, Dan Yang, Liang Xin, Jingyi Li, Qianqian Zhao, Minghui Chang, Huafeng Qi, Zhuanmei Yuan, Wenbo Yao, Guaiping Qiao, Juan Li, Nan Hui, Han Li
  • Pleuromulin acitretin ester with antibacterial activity and a method of preparing the same
    Patent number: 11155514
    Abstract: A compound with anti-drug resistant bacteria activity having the following formula (I) is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Grant
    Filed: December 19, 2020
    Date of Patent: October 26, 2021
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Bin Tian, Juan Li, Nan Hui, Guaiping Qiao, Liang Xin, Jingyi Li, Dan Yang, Han Li, Yanjun Li, Liang Qi, Wenbo Yao, Chengyuan Liang
  • Security system and method of stored data
    Patent number: 11010312
    Abstract: A security system and a security method of stored data are provided. In the security system and the security method, a central processing unit performs hashing operation on a seed code to generate a data access code, which is then compared with a password stored in a storage device. If there is no password in the storage device, the data access code is written into the storage device as the password. On the other hand, if the data access code does not match the password, the storage device denies the access request from the central processing unit.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: May 18, 2021
    Assignee: VIA TECHNOLOGIES, INC.
    Inventors: Nan Hui Li, Neng-An Kuo
  • Hydroxytyrosol ursolic acid ester with antioxidant activity and methods of preparing the same
    Patent number: 10995053
    Abstract: A compound having the formula (I): is disclosed. Methods of preparing the compound of formula (I) are also disclosed. The compound of formula (I) can be prepared by reacting a compound of formula (II) with a compound of formula (III) in an organic solvent with EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide). The compound of formula (I) can also be prepared by reacting the compound of formula (II) with the compound of formula (III) in 1-ethyl-3-methylimidazolium hexafluorophosphate as a solvent with silicomolybdic acid as a catalyst.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: May 4, 2021
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Han Li, Nan Hui, Bin Tian, Xingke Ju, Yuzhi Liu, Dan Yang, Jingwen Xu, Liang Qi, Qianqian Zhao, Yongbo Wang
  • Cinnamyl alcohol cassic acid ester with antibacterial activity and a method of preparing the same
    Patent number: 10947182
    Abstract: A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Grant
    Filed: June 27, 2020
    Date of Patent: March 16, 2021
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Han Li, Nan Hui, Chengyuan Liang, Xingke Ju, Guaiping Qiao, Juan Li, Yuanyuan He, Bin Tian, Yongbo Wang, Jingwen Xu, Liang Qi, Dan Yang, Qiangian Zhao, Yanjun Li, Qiao Zeng, Gennian Mao, Limei Wang
  • 6-aminouracil cassic acid ester with antibacterial activity and a method of preparing the same
    Patent number: 10941120
    Abstract: A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: March 9, 2021
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Han Li, Nan Hui, Chengyuan Liang, Xingke Ju, Guaiping Qiao, Juan Li, Yuanyuan He, Bin Tian, Yongbo Wang, Jingwen Xu, Liang Qi, Dan Yang, Qianqian Zhao, Yanjun Li, Qiao Zeng, Gennian Mao, Limei Wang
  • Hydroxytyrosol 4-methoxycinnamic acid ester with antibacterial activity and a method of preparing the same
    Patent number: 10906863
    Abstract: A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: February 2, 2021
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Gennian Mao, Limei Wang, Bin Tian, Xingke Ju, Nan Hui, Juan Li, Guaiping Qiao, Dan Yang, Jingwen Xu, Liang Qi, Wenbo Yao, Han Li, Chengyuan Liang
  • METHOD FOR EXTRACTING HERBAL MEDICINE
    Publication number: 20200376056
    Abstract: A method for extracting herbal medicine includes: step one, spray extraction; step two, pressure filtration and concentration; step three, spray and countercurrent precipitation; and step four, concentrating reduced pressure and drying.
    Type: Application
    Filed: August 14, 2020
    Publication date: December 3, 2020
    Applicant: SHAANXI PANLONG PHARMACEUTICAL GROUP LIMITED BY SHARE LTD.
    Inventors: Xiaolin XIE, Dezhu ZHANG, Jianguo MENG, Yu WANG, Xuhua ZHOU, Zhong MENG, Nan HUI, Juan LI
  • A LILAC GINKGO BRICK TEA WITH LIPID LOWERING AND LIVER PROTECTION ACTIVITIES AND A METHOD OF PREPARING THE SAME
    Publication number: 20200353027
    Abstract: A method of preparing a Lilac Ginkgo Brick Tea includes the following steps: (1) mixing and drying fresh Lilac leaves and Ginkgo leaves to obtain a Lilac Ginkgo Tea; (2) fermenting the Lilac Ginkgo Tea to obtain a Fermented Lilac Ginkgo Tea; (3) mixing the Fermented Lilac Ginkgo Tea with a black tea to obtain a Fermented Lilac Ginkgo Tea Mixture; and (4) processing the Fermented Lilac Ginkgo Tea Mixture to obtain the Lilac Ginkgo Brick Tea.
    Type: Application
    Filed: October 20, 2019
    Publication date: November 12, 2020
    Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan LIANG, Nan HUI, Chunyang SHI, Han LI, Bin TIAN, Gennian MAO, Qianqian ZHAO, Qiao ZENG
  • Device for high pressure spray and counter-current precipitation extraction of herbal medicine and a method for extracting herbal medicine using the same
    Patent number: 10772921
    Abstract: A device for high pressure spray and counter-current precipitation extraction of herbal medicine is disclosed. A method for extracting herbal medicine using the device is also disclosed.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: September 15, 2020
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chengyuan Liang, Nan Hui, Juan Li, Guaiping Qiao, Yonghong Tang, Gennian Mao, Han Li, Bin Tian, Qianqian Zhao, Yongbo Wang, Dan Yang, Hanyang Liu
  • Hydroxytyrosol ursodeoxycholic acid ester with antioxidant activity and a method of preparing the same
    Patent number: 10738077
    Abstract: A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: August 11, 2020
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Wenbo Yao, Guaiping Qiao, Juan Li, Nan Hui, Qiao Zeng, Han Li, Bin Tian, Yongbo Wang, Dan Yang, Jingwen Xu, Liang Qi, Yanjun Li, Chengyuan Liang
  • Crotonyl alcohol cassic acid ester with antibacterial activity and a method of preparing the same
    Patent number: 10717699
    Abstract: A compound having the formula (I): (I) is disclosed. A method of preparing the compound of formula (I) is also disclosed.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: July 21, 2020
    Assignee: SOUTHWEST UNIVERSITY
    Inventors: Lei Luo, Shinan Jiang, Yonghuang Luo, Han Li, Nan Hui