Abstract: A system and method for enabling remote management of data of devices using wireless communications. The system and method provides direct access to devices such as sensors from wireless devices having an integrated wireless transceiver and controller that are user programmable such a separate remote host controller is not required for managing the sensors. In one embodiment, a broadcast mode is provided wherein the wireless devices transmits a response for its corresponding sensors according to a predetermined sequence during a predetermined time slot according to a predetermined sequence.

Abstract: This invention provides compounds of Formula (1a)-(1f), II wherein: X, m, n, q, R1, R2, R3, R4, R5, R6, R7, R8, R9, Y, Q, Z, Z?, Z??, Z? and J are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, myocardial infarction, neuropathic pain, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.

Abstract: A system for multiplexing photodetector signals from a scintillation detector. The system includes a detector module having a number of scintillator blocks, each scintillator block having a number of photosensors, and a number of multiplexing circuits. Each multiplexing circuit includes a number of inputs, a signal polarity inverter and at least one differential output attached to the signal polarity inverter. The multiplexing system inverts the polarity of preselected signals from the photosensors and selectively combines signals of different polarities to calculate event positioning and total energy.

Abstract: This invention relates to certain 6-aryl-7-halo-imidazo[1,2-a]pyrimidines or pharmaceutically acceptable salts thereof, and compositions containing said compounds or pharmaceutically acceptable salts thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals by promotion of microtubule polymerization. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or pharmaceutically acceptable salts thereof.

Abstract: This invention provides compounds of Formula (1a)–(1f), II wherein: X, m, n, q, R1, R2, R3, R4, R5, R6, R7, R8, R9, Y, Q, Z, Z?, Z??, Z? and J are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, myocardial infarction, neuropathic pain, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.

Abstract: APD-based PET modules are provided for use in combined PET/MR imaging. Each module includes a number of independent, optically isolated detectors. Each detector includes an array of scintillator (e.g. LSO) crystals read out by an array of APDs. The modules are positioned in the tunnel of a MR scanner. Simultaneous, artifact-free images can be acquired with the APD-based PET and MR system resulting in a high-resolution and cost-effective integrated PET/MR system.

Abstract: This invention provides compounds of formula 1, having the structure which are useful as inhibitors of protein tyrosine kinase and are antiproliferative agents.

Abstract: This invention provides compounds of formula 1, having the structure which are useful as inhibitors of protein tyrosine kinase and are antiproliferative agents.

Abstract: This invention relates to novel pyrazolo[1,5-a]pyrimidine compounds and the therapeutically acceptable salts thereof. These compounds are useful as anti-proliferative agents in mammals, including humans.

Abstract: This invention relates to novel methods of use of certain pyrazolo[1,5-a]pyrimidine compounds and the therapeutically acceptable salts thereof. This invention also relates to novel methods of using these compounds as anti-proliferative agents in mammals, including humans.

Abstract: This invention provides compounds of Formula (1a)-(1f) wherein: X, R1, and R2 are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.

Abstract: The present invention provides for a 1×N optical switch having a switching component, an input, and a plurality of outputs formed in a single substrate. The switching component includes a pair of mirrors which are operated such that by changing the position of at least one of the mirrors, the output of the switch changes.

Abstract: This invention relates to certain 6-[(substituted)phenyl]triazolopyrimidine compounds or pharmaceutically acceptable salts thereof, and compositions containing said compounds or pharmaceutically acceptable salts thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or pharmaceutically acceptable salts thereof.

Abstract: This invention relates to certain 5-arylpyrimidine compounds or a pharmaceutically acceptable salt thereof, and compositions containing said compounds or a pharmaceutically acceptable salt thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or a pharmaceutically acceptable salt thereof.

Abstract: This invention relates to certain 6-aryl-7-halo-imidazo[1,2-a]pyrimidines or pharmaceutically acceptable salts thereof, and compositions containing said compounds or pharmaceutically acceptable salts thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals by promotion of microtubule polymerization. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or pharmaceutically acceptable salts thereof.

Abstract: This invention provides compounds of Formula (1a)-(1f), II 1

Abstract: A MEMS-based latching device is described. In accordance with one embodiment, a micro electromechanical system is formed on a substrate. The system includes a positionable member capable of being moved between at least two positions relative to the substrate. An actuator such as a comb drive actuator is provided which may include a stationary comb mounted on the substrate, a moveable comb interleaved with the stationary comb, and a beam connected between the substrate and the moveable comb. The comb drive actuator is coupled to a latching member so that the latching member can be moved between a first position and a second position. In the first position, the latching member engages the positionable member to prevent the positionable member from moving. In the second position, the latching member is disengaged from the positionable member to allow movement of the positionable member. The combs of the comb drive actuator deflect the beam to move the latching member from the first to the second position.

Abstract: This invention provides compounds of Formula (I), having the structure 1

Abstract: This invention provides compounds of Formula (Ia)-(If) 1

Abstract: This invention provides compounds of formula 1, having the structure 1