Patents by Inventor Nao Funakoshi

Nao Funakoshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process of producing glutamate derivatives
    Patent number: 8563278
    Abstract: A process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin is described. This process entails converting a substituted ?-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
    Type: Grant
    Filed: August 10, 2010
    Date of Patent: October 22, 2013
    Assignee: Ajinomoto Co., Inc.
    Inventors: Masakazu Sugiyama, Kunihiko Watanabe, Nao Funakoshi, Yusuke Amino, Shigeru Kawahara, Tadashi Takemoto
  • Process for producing glutamate derivatives
    Patent number: 8535920
    Abstract: The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted ?-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: September 17, 2013
    Assignee: Ajinomoto Co., Inc.
    Inventors: Masakazu Sugiyama, Kunihiko Watanabe, Nao Funakoshi, Yusuke Amino, Shigeru Kawahara, Tadashi Takemoto
  • Process for producing glutamate derivatives
    Patent number: 8202711
    Abstract: The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted ?-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: June 19, 2012
    Assignee: Ajinomoto Co., Inc.
    Inventors: Masakazu Sugiyama, Kunihiko Watanabe, Nao Funakoshi, Yusuke Amino, Shigeru Kawahara, Tadashi Takemoto
  • PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES
    Publication number: 20120035373
    Abstract: The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products.
    Type: Application
    Filed: October 14, 2011
    Publication date: February 9, 2012
    Applicant: AJINOMOTO CO. INC
    Inventors: Shigeru KAWAHARA, Nao FUNAKOSHI
  • PROCESS FOR PRODUCING GLUTAMATE DERIVATIVES
    Publication number: 20110189738
    Abstract: The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted ?-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
    Type: Application
    Filed: March 10, 2011
    Publication date: August 4, 2011
    Applicant: Ajinomoto Co., Inc.
    Inventors: Masakazu SUGIYAMA, Kunihiko WATANABE, Nao FUNAKOSHI, Yusuke AMINO, Shigeru KAWAHARA, Tadashi TAKEMOTO
  • Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes
    Patent number: 7868187
    Abstract: The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products.
    Type: Grant
    Filed: June 23, 2009
    Date of Patent: January 11, 2011
    Assignee: Ajinomoto Co., Inc.
    Inventors: Shigeru Kawahara, Nao Funakoshi
  • PROCESS OF PRODUCING GLUTAMATE DERIVATIVES
    Publication number: 20100323411
    Abstract: The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted ?-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
    Type: Application
    Filed: August 10, 2010
    Publication date: December 23, 2010
    Applicant: AJINOMOTO CO., INC.
    Inventors: MASAKAZU SUGIYAMA, KUNIHIKO WATANABE, NAO FUNAKOSHI, YUSUKE AMINO, SHIGERU KAWAHARA, TADASHI TAKEMOTO
  • PROCESS FOR PRODUCING GLUTAMATE DERIVATIVES
    Publication number: 20100261234
    Abstract: The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted ?-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
    Type: Application
    Filed: April 27, 2010
    Publication date: October 14, 2010
    Applicant: Ajinomoto Co., Inc.
    Inventors: Masakazu SUGIYAMA, Kunihiko Watanabe, Nao Funakoshi, Yusuke Amino, Shigeru Kawahara, Tadashi Takemoto
  • PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES
    Publication number: 20100105924
    Abstract: The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products.
    Type: Application
    Filed: November 6, 2009
    Publication date: April 29, 2010
    Applicant: AJINOMOTO CO. INC.
    Inventors: Shigeru KAWAHARA, Nao FUNAKOSHI
  • Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes
    Patent number: 7678925
    Abstract: The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products.
    Type: Grant
    Filed: December 6, 2007
    Date of Patent: March 16, 2010
    Assignee: Ajinomoto Co., Inc.
    Inventors: Shigeru Kawahara, Nao Funakoshi
  • PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES
    Publication number: 20090259052
    Abstract: The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products.
    Type: Application
    Filed: June 23, 2009
    Publication date: October 15, 2009
    Applicant: AJINOMOTO CO. INC
    Inventors: Shigeru KAWAHARA, Yusuke AMINO, Kenichi MORI, Nao FUNAKOSHI, Tadashi TAKEMOTO
  • PROCESS FOR PRODUCING GLUTAMATE DERIVATIVES
    Publication number: 20080199921
    Abstract: The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted ?-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
    Type: Application
    Filed: April 24, 2008
    Publication date: August 21, 2008
    Applicant: Ajinomoto Co., Inc.
    Inventors: Masakazu Sugiyama, Kunihiko Watanabe, Nao Funakoshi, Yusuke Amino, Shigeru Kawahara, Tadashi Takemoto
  • Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes
    Patent number: 7390909
    Abstract: The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products.
    Type: Grant
    Filed: November 22, 2005
    Date of Patent: June 24, 2008
    Assignee: Ajinomoto Co., Inc.
    Inventors: Shigeru Kawahara, Yusuke Amino, Kenichi Mori, Nao Funakoshi, Tadashi Takemoto
  • PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES
    Publication number: 20080091032
    Abstract: The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products.
    Type: Application
    Filed: December 6, 2007
    Publication date: April 17, 2008
    Applicant: AJINOMOTO CO. INC
    Inventors: Shigeru KAWAHARA, Yusuke Amino, Kenichi Mori, Nao Funakoshi, Tadashi Takemoto
  • Process of producing glutamate derivatives
    Patent number: 7297800
    Abstract: The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted ?-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same
    Type: Grant
    Filed: June 28, 2004
    Date of Patent: November 20, 2007
    Assignee: Ajinomoto Co., Inc.
    Inventors: Masakazu Sugiyama, Kunihiko Watanabe, Nao Funakoshi, Yusuke Amino, Shigeru Kawahara, Tadashi Takemoto
  • PROCESS FOR PRODUCING GLUTAMATE DERIVATIVES
    Publication number: 20070072277
    Abstract: The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted ?-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
    Type: Application
    Filed: November 20, 2006
    Publication date: March 29, 2007
    Applicant: Ajinomoto Co., Inc.
    Inventors: Masakazu Sugiyama, Kunihiko Watanabe, Nao Funakoshi, Yusuke Amino, Shigeru Kawahara, Tadashi Takemoto
  • Process for producing cinnamaldehyde derivatives, use thereof and the like
    Patent number: 7141263
    Abstract: A process for conveniently and efficiently producing a highly pure cinnamaldehyde derivative, for example, (2E)-(3-hydroxy-4-methoxy)cinnamaldehyde, which comprises reacting a benzaldehyde derivative, such as isovanillin and the like, with acetaldehyde in the presence of an alkali, in particular preferably, dropping acetaldehyde little by little thereto in an aqueous solution at a low temperature for the reaction thereof. The cinnamaldehyde derivative thus obtained is selectively reduced to produce 3-(3-hydroxy-4-substituted (with methoxy group or the like)phenyl)propionaldehyde. Further, through a reductive alkylation reaction of the compound thus produced with an aspartame, N-[N-[3-(3-hydroxy-4-substituted (with methoxy group or the like)phenyl)propyl]-L-aspartyl]-L-phenylalanine 1-methyl ester, which is useful as a sweetener having a high sweetening potency, can be industrially and efficiently produced. The processes therefor are also provided.
    Type: Grant
    Filed: June 17, 2005
    Date of Patent: November 28, 2006
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kenichi Mori, Shinji Fujita, Nao Funakoshi, Tadashi Takemoto
  • Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes
    Patent number: 7064219
    Abstract: The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products.
    Type: Grant
    Filed: June 22, 2004
    Date of Patent: June 20, 2006
    Assignee: Ajinomoto Co., Inc.
    Inventors: Shigeru Kawahara, Yusuke Amino, Kenichi Mori, Nao Funakoshi, Tadashi Takemoto
  • Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes
    Publication number: 20060074249
    Abstract: The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products.
    Type: Application
    Filed: November 22, 2005
    Publication date: April 6, 2006
    Applicant: AJINOMOTO CO. INC
    Inventors: Shigeru Kawahara, Yusuke Amino, Kenichi Mori, Nao Funakoshi, Tadashi Takemoto
  • Process for producing cinnamaldehyde derivatives, use thereof and the like
    Patent number: 6965055
    Abstract: A process for conveniently and efficiently producing a highly pure cinnamaldehyde derivative, for example, (2E)-(3-hydroxy-4-methoxy)cinnamaldehyde, which comprises reacting a benzaldehyde derivative, such as isovanillin and the like, with acetaldehyde in the presence of an alkali, in particular preferably, dropping acetaldehyde little by little thereto in an aqueous solution at a low temperature for the reaction thereof. The cinnamaldehyde derivative thus obtained is selectively reduced to produce 3-(3-hydroxy-4-substituted (with methoxy group or the like)phenyl) propionaldehyde. Further, through a reductive alkylation reaction of the compound thus produced with an aspartame, N-[N-[3-(3-hydroxy-4-substituted (with methoxy group or the like)phenyl) propyl]-L-?-aspartyl]-L-phenylalanine 1-methyl ester, which is useful as a sweetener having a high sweetening potency, can be industrially and efficiently produced. The processes therefor are also provided.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: November 15, 2005
    Assignee: Ajinomoto Co., Ltd.
    Inventors: Kenichi Mori, Shinji Fujita, Nao Funakoshi, Tadashi Takemoto